Digital Commons Network^™

Dyslipidemia And Serum Mineral Profiles In Patients With Thyroid Disorders, Abdelgayoum A. Abdel-Gayoum

Saudi Medical Journal

OBJECTIVES: To investigate changes in serum lipid profile, levels of serum minerals associated with thyroid disorders, and to compare these with the serum lipid and mineral profiles in hypothyroid patients receiving thyroxine therapy. METHODS: A cross-sectional study was conducted in King Khaled Hospital, Hail, Saudi Arabia. The patient database was searched for new patients with thyroid dysfunction between January 2011 and June 2012. They were classified into 5 groups: 1) subclinical-hypothyroid (SHY), 2) overt-hypothyroid (OHY), 3) subclinical-hyperthyroid (SHE), 4) overt-hyperthyroid (OHE), 5) patients under thyroxine therapy (EU), and normal controls. RESULTS: The OHY group showed impaired renal function; whereas, the …

Molecular Mechanisms Of Anti-Hyperglycemic Effects Of Costus Speciosus Extract In Streptozotocin-Induced Diabetic Rats, Haytham A. Ali, Omar A. Almaghrabi, Mohamed E. Afifi

Saudi Medical Journal

OBJECTIVES: To investigate the mechanisms of the anti-hyperglycemic effect of Costus speciosus (C. speciosus) root ethanolic extracts (CSREt) by assessing its action on insulin synthesis and glucose catabolic enzyme gene expression and activities in streptozotocin (STZ) diabetic rats. METHODS: This study was carried out at the Biochemical Laboratory, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt between July and August 2013. Sixty male albino rats (120 +/- 20 g weight, and 6 months old) were used and divided into 6 groups (n=10). Two groups served as diabetic and nondiabetic controls. Four groups of STZ diabetic animals were given oral C. …

Speed Kills: Ineffective Avian Escape Responses To Oncoming Vehicles, Travis L. Devault, Bradley F. Blackwell, Thomas W. Seamans, Steven L. Lima, Esteban Fernandez-Juricic

United States Department of Agriculture Wildlife Services: Staff Publications

Animal–vehicle collisions cause high levels of vertebrate mortality worldwide, and what goes wrong when animals fail to escape and ultimately collide with vehicles is notwell understood.We investigated alert and escape behaviours of captive brown-headed cowbirds (Molothrus ater) in response to virtual vehicle approaches of different sizes and at speeds ranging from 60 to 360 km h^-1. Alert and flight initiation distances remained similar across vehicle speeds, and accordingly, alert and flight initiation times decreased at higher vehicle speeds. Thus, avoidance behaviours in cowbirds appeared to be based on distance rather than time available for escape, particularly …

Montclair Magazine (Fall/Winter 2014), Montclair State University

Montclair: The magazine of Montclair State University

No abstract provided.

Service-Learning, Sustainability, And The Need For Cosmopolitan Experiences In Undergraduate Education: A View From Anthropology, David Syring

eJournal of Public Affairs

To become citizens of the world, students must understand with their heads, hands, and hearts the complex realities that people live within in a globalizing but nonetheless richly diverse world. A short-term study-abroad program, while brief in duration, may profoundly affect student learning and, indeed, transform life paths by providing students real experiences of cosmopolitan consciousness. The program described below and represented by the accompanying videos focuses on immersive, service-based learning in Costa Rica for the purpose of exploring sustainability in its multiple registers—social, environmental, and economic. Student reflection and commentary from our Costa Rican host institution confirm that programs …

The Predicts Database: A Global Database Of How Local Terrestrial Biodiversity Responds To Human Impacts, Lawrence N. Hudson, Tim Newbold, Sara Contu, Samantha L.L. Hill, Igor Lysenko, Adriana De Palma, Helen R.P. Phillips, Rebecca A. Senior, Dominic J. Bennett, Hollie Booth, Argyrios Choimes, David L.P. Correia, Julie Day, Susy Echeverría-Londoño, Morgan Garon, Michelle L.K. Harrison, Daniel J. Ingram, Martin Jung, Victoria Kemp, Lucinda Kirkpatrick, Callum D. Martin, Yuan Pan, Hannah J. White, Job Aben, Stefan Abrahamczyk, Gilbert B. Adum, Virginia Aguilar-Barquero, Marcelo A. Aizen, Marc Ancrenaz, Enrique Arbeláez-Cortés, Inge Armbrecht, Badrul Azhar, Christopher A. Williams

Geography

Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species' threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that support computation of a range of biodiversity indicators, is necessary to enable better understanding of historical declines and to project - and avert - future declines. We describe and assess a new database of more than 1.6 million samples from 78 countries representing over 28,000 species, collated from existing spatial …

Developing The Modern Heroine Of Fantasy Literature: An Examination Of Lyra From "His Dark Materials" And Clary From "The Mortal Instruments", Diana Aileen Borghols Herrera

Theses and Dissertations - UTB/UTPA

This work looks at the figure of the heroine as present through the characters of Lyra Belacqua in His Dark Materials and Clary Fairchild in The Mortal Instruments. The characters will be analysed within the fantasy genre and the tradition of the heroic figure. By defining the hero and the heroine, two types of characters with different traits, I will show that the heroic archetype for the female is not entirely set. Lyra and Clary share some similarities but their relation to their respective role is perceived and fulfilled through varying degrees of commitment. The analysis will be contained to …

La Intencion Pictorica En Tres Novelas De Corte Realista De Ana Maria Matute, Viviana Carvajal

Theses and Dissertations - UTB/UTPA

This thesis proposes a study about the profound relationship existing in the literary production of the Spanish author, Ana María Matute, between the poetic language found in her narrative and the Visual Arts. While a number of critics and researchers have analyzed in depth the works of this author, there is no abundance of studies that explore the pictorial intention found in them. Likewise, there are scarce or marginal contributions focused on the notion of ekphrasis in connection to her narrative. In order to analyze the rhetoric structure in Matute’s narrative, a definition of “space” as a literary category is …

A Comparative Study Of Domestic And Hospital Environmental Microbial Populations In Al-Ain (Uae), Amna Ali Jaffal

Theses

This is the first attempt to estimate biological indoor pollution in the environment of AI-Ain city. The numbers and types of bacteria and fungi in the air and on the surfaces were measured in AI-Ain hospital and three different types of domestic environments.

Five different types of wards at AI-Ain hospital, medical, surgical, pediatrics, operating theater, and intensive care unit were studied. Their estimated indoor bioaerosols were compared to indoor bioaerosols in three types of dwelling houses, very good, average, and poor quality houses in AI-Ain city. A bacteriological mechanical air sampler, MK2 (Casella London) was used in this study. …

Orchestrating Service Innovation Using Design Moves: The Dynamics Of Fit Between Service And Enterprise It Architectures, Narayan Ramasubbu, Charles Jason Woodard, Sunil Mithas

Research Collection School Of Computing and Information Systems

Service science perspectives highlight the central role of information technology (IT) in transforming the design and delivery of services. To discern the mechanisms through which IT impacts service innovation, we explore the dynamics of the relationship between enterprise IT and service architectures, and how these dynamics influence the performance of service innovation projects. We conducted six case studies to investigate how firms orchestrated service innovation, focusing on the design of the service architecture and its relationship to enterprise systems. We synthesize the case findings to develop a set of propositions on the antecedents and consequences of fit (or misfit) between …

Feed Efficiency: An Assessment Of Current Knowledge From A Voluntary Subsample Of The Swine Industry, Josh R. Flohr, Mike D. Tokach, Joel M. Derouchey, Robert D. Goodband, Steve S. Dritz, Jim L. Nelssen, John F. Patience

Journal of Extension

A voluntary sample of pork producers and advisers to the swine industry were surveyed about feed efficiency. The questionnaire was designed to accomplish three objectives: (a) determine the level of knowledge related to feed efficiency topics, (b) identify production practices used that influence feed efficiency, and (c) identify information gaps requiring additional knowledge to further improve feed efficiency. Results suggest that many practices that improve feed efficiency are used in production, but gaps in information and knowledge exist across demographics of respondents. Extension education should be expanded to provide more information in an easy-to-access format for the swine industry.

4-H And Aquatic Robotics, Brian Mcneill, Patrick Jirik, Bradley Rugg

Journal of Extension

4-H is positioned to engage youth in the areas of environment and engineering. This article shares how Minnesota is engaging youth and adults to identify and solve community issues with the use of an aquatic remotely operated vehicle (ROV). After creating a new program design, the team has attracted new skilled volunteers and new youth to create youth-adult partnerships to take action in the community.

Effect Of Thermal Treatments On Mechanical Properties And Bioactivity Of Third Generation Of Bioactive Glass. A Step For Commercialization Success Of Third Generation Bioactive Glasses, Rajan Pandya

Theses and Dissertations

Unavailability of donors for transplanting bone to help people with orthopedic imparities gave rise to the metal implants that could be made in factories. This seemed like a good solution as it was available to all the people who needed it. It came with limitations such as restricted movement, infection, wear and tear of the surrounding tissue, and rejection. Biologically active implants were introduced by Dr. Larry Hench in 1960s [12]. The field of regenerative medicine has been changing rapidly since then. Biologically active implants facilitate bone regeneration and do not harm the surrounding tissue in any way. The bioactive …

Metamorphosis Of Limulus Polyphemus Trilobite Larvae: Role Of Chemical And Structural Cues, Competency, And The Cost Of Delayed Metamorphosis, Stephanie Marie Kronstadt

Theses and Dissertations

Many marine and estuarine arthropods exhibit complex life cycles that include planktonic larval stages and benthic juvenile and adult phases. Chemical and structural cues associated with juvenile habitats often induce settlement and metamorphosis, thereby shortening the duration of the larval phase. These cues can trigger metamorphosis only after larvae reach competency, or developmental maturity. The point at which larvae reach this competency period and the ability to retain competency is highly species specific. Once competency is attained, a decrease in the time to metamorphosis (TTM) can decrease dispersal potential but may increase the chance of settling in a suitable habitat. …

The Conservation Genetics Of Two Emydid Turtles: Emydoidea Blandingii And Malaclemys Terrapin, Charlotte Lizana Petre

Master's Theses

Conservation of turtles is complicated by their sensitivity to habitat degradation and overexploitation. I used microsatellites and standard population genetic analyses to explore genetic diversity, population structure, paternity and demographic history in two emydid turtles that are currently experiencing threats to their survival. The Blanding’s turtle, Emydoidea blandingii, has experienced habitat fragmentation throughout its range, and this study focuses on a population in Massachusetts where hatchlings from one population are being translocated to establish a new population. I found evidence of multiple paternity within clutches and found no significant reduction in genetic diversity when comparing the source population and …

Modeling The Evolution Of Generativity And The Emergence Of Digital Ecosystems, C. Jason Woodard, Eric K. Clemons

Research Collection School Of Computing and Information Systems

Recent literature on sociotechnical systems has employed the concept of generativity to explain the remarkable capacity for digital artifacts to support decentralized innovation and the emergence of rich business ecosystems. In this paper, we propose agent-based computational modeling as a tool for studying the evolution of generativity, and offer a set of building blocks for constructing agent-based models in which generativity evolves. We describe a series of models that we have created using these building blocks, and summarize the results of our computational experiments to date. We find in several different settings that key features of generative systems can themselves …

Screening For Novel Inhibitors Of Αlpha-Ynuclein Seeded Nucleation-Dependent Aggregation And Toxicity As A Potential Therapeutic Strategy For Parkinson’S Disease, Mustafa Taleb Ardeh

Dissertations

α-Synuclein aggregation is the key pathogenic event in several important neurological disorders including Parkinson’s Disease, dementia with Lewy bodies and multiple system atrophy, giving rise to a distinct group of neurodegenerative diseases known as synucleinopathies. Although the molecular basis of α-syn toxicity has not been precisely elucidated, recent studies indicate that α-syn toxicity is mediated by a nucleation-dependent aggregation process. To elucidate the structural basis of α-synuclein mediated toxicity, we developed various methods to prepare different α-synuclein species of a defined size and morphology distribution, and we investigated their toxicity in different human dopaminergic cell lines. We observed that crude …

Lights Out In The Bakken: A Review And Analysis Of Flaring Regulation And Its Potential Effects On North Dakota Shale Oil Production, Monika U. Ehrman

West Virginia Law Review

No abstract provided.

Neuroprotective Effect Of An Α-7 Nicotinic Acetylcholine Receptor Agonist And A Positive Allosteric Modulator In An In Vitro Model Of Glaucoma, Leah Lyons

Masters Theses

Glaucoma is one of several neurodegenerative diseases of the central nervous system for which a pharmacologic cure is yet to be discovered. In previous studies acetylcholine (ACh) has provided neuroprotection for retinal ganglion cells (RGC) in the mammalian retina under glaucomatous conditions (Wehrwein et al., 2004). More specifically, an α7 nicotinic ACh receptor (nAChR) agonist has demonstrated neuroprotection for RGCs in both in vitro and in vivo models of glaucoma (Iwamoto et al., 2014). In this study, this α7 nAChR agonist was combined with a positive allosteric modulator (PAM) in dissociated adult porcine retinas to evaluate its effect on isolated …

Bacteriophage Host-Range Expansion To Include Two Strains Of Clostridium Sporogenes, Kevin K. Crown

Biology ETDs

Bacteriophages are viruses that infect bacteria, which have been used to treat bacterial infections in people for decades. They are also now being used as FDA approved preservatives as a means to prevent the growth of spoiling bacteria in many ready-to-eat foods. Bacteriophages tend to infect a very narrow range of bacterial hosts, some only a single sub-strain. When used for therapeutics or food treatment however, it is desirable to use phages that are promiscuous in their host range. This has led to attempts to broaden the host range of the most useful phages. By passaging phages in co-cultures of …

Effect Of Teriparatide On Bone Regenerate After Distraction Osteogenesis, Masood Umer, Tashfeen Ahmad, Sadia Habib, Rasham Rehman, Mahmood Ahmed, Irfan Qadir

Department of Surgery Docs

Abstract

OBJECTIVE:

To determine the effect of teriparatide on new bone formation in a rat model of distraction osteogenesis.

METHODS:

The experimental study was conducted at the Aga Khan University Hospital, Karachi, in November-December 2010, and comprised male Sprague-Dawley rats weighing 250gm each who were allocated to two treatment groups, teriparatide and saline, both given subcutaneously for 7 weeks. Femoral distraction was done for 3 weeks at the rate of 0.4mm/day, followed by a further 4 weeks for consolidation. New bone formation was assessed using X-ray scoring system, bone densitometry and histology.

RESULTS:

The 12 rats in the study were …

“Historically As Certain As Our Revolution Itself”: The Nullifiers And History, William E. Hopchak

Senior Honors Theses

Despite the common defamation of the states’ rights theories acted upon in the Nullification Crisis of 1832, there exists a great deal of historical support for the nullifiers’ positions. Nullifiers believed in a decentralized constitutional system, while nationalists believed in a centralized constitutional system. This tension between central and decentralized positions had been at issue in the American struggle for independence though the exact manner in which these problems manifested themselves was different in the two events. The states’ rights ideas championed primarily by John C. Calhoun were consistent with American political tradition. At the most basic level, the Nullification …

Cal Poly India Project, Derek Babine, Austen Hibler, Alex Hernandez

Mechanical Engineering

This report documents the research, ideation, and development of a solution, implemented by the Cal Poly India Sanitation Team per the request of Mr. Harish Bhutani, to solve the problem of hazardous human waste management in poor villages in India. The sponsor envisioned a universal design that would give each household in those villages access to a private toilet system because the current solution is open defecation in water sources and farming fields. The initial constraints required the project be low cost, not use of electricity or water, have the ability to cater to an 8-10 person household, and be …

Printed Electronics Applications For Publications, Abel Marquez

Graphic Communication

The purpose of this research was to demonstrate that the printing industry can potentially benefit from the incorporation of printed electronics into the publications and packaging fields. Taking advantage of this technology would attract more consumers, especially younger generations who are immersed in the digital world and feel more engaged with products that offer user interactivity.

Experts in the field were interviewed to get information and feedback about the project. Also, a survey was conducted. Cal Poly students, from different areas and departments were included to see if they would be interested in subscribing or buying a magazine that incorporates …

Compositing Brought To Life, Anika Morris

Liberal Arts and Engineering Studies

No abstract provided.

Aquaponics Art, Alexander Horton

Liberal Arts and Engineering Studies

Aquaponics has enormous potential to change the way we farm. I wanted to connect more people to Cal Poly's first aquaponics club by creating a functioning aquaponics art installation that allows people to plant their own plants. This paper is catalog of the design process as a reflection of what this project hopes to accomplish.

Developing A Tool For Site-Specific Gene Inactivation In Chlamydia, Cayla Marie Johnson

Theses

Chlamydia trachomatis is an obligate intracellular bacterial pathogen that infects both humans and domestically important animals. Research in the field has until more recently been hindered by a lack of genetic tools. We have modified Sigma's TargeTron^TM Gene Knockout System, which utilizes a mobile group II intron for site-specific insertion and gene inactivation, for use in C. trachomatis. As proof of principle, we used the system to inactivate incA, creating mutant strains DFCT3 and DFCT4 (independent clones both carrying incA::GII[bla]). IncA is a chlamydial inclusion membrane protein involved in homotypic fusion of inclusions when cells are infected with more …

Effect Of Different Extrusion Processing Parameters On Physical Properties Of Soy White Flakes And High Protein Distillers Dried Grains-Based Extruded Aquafeeds, Sushil Kumar Singh, Kasiviswanathan Muthukumarappan

Agricultural and Biosystems Engineering Publications

Nutritionally balanced ingredient blends for catla (Catla catla), belonging to the family Cyprinidae, were extruded using single screw extruder. The extrusion was carried out at five levels of soy white flakes content (21%, 29%, 40%, 52%, and 59% db), five levels of moisture content (15, 19, 25, 31, and 35% db) and five levels of barrel temperature (100, 110, 125, 140, and 150 ºC) using three different die nozzles (having L/D ratios 3.33, 5.83, and 7.25). Blends with net protein content of 32.5% contains soy white flakes, along with high protein distillers dried grains (HP-DDG), corn flour, corn gluten meal, …

Functional Morphology Of The Connective Tissue Of The Clavicular System Of The Domestic Cat, Felis Catus, Amanda N. Cooper

Honors Capstones

No abstract provided.

An Exploration Of Cell Cycle Regulation In Arabidopsis Thaliana Trichomes, Ashley Willis

Honors Capstones

No abstract provided.