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Mrp4-Dependent Regulation Of Fibroblast Migration, Chandrima Sinha

Theses and Dissertations (ETD)

Roles of cyclic nucleotides and cyclic nucleotide-dependent signaling molecules in regulating several signaling pathways including cell migration have long been known. However, the new and revolutionary concept is that it is not just the absence or presence of cyclic nucleotides, but a highly coordinated balance between these molecules regulates cell migration. Multi-drug resistance protein 4 (MRP4), is a member of the large family of ATP binding cassette (ABC) transporter proteins, that localizes to the plasma membrane and functions as a nucleotide efflux transporter and thus plays a pivotal role in the regulation of intracellular cyclic nucleotide dynamics. In our study …

Downregulation Of Prdm16 Is Critical For Hoxb4-Mediated Benign Hsc Expansion In Vivo, Hui Yu

Theses and Dissertations (ETD)

Overexpression of HOXB4 in hematopoietic stem cells (HSCs) leads to increased self-renewal without causing hematopoietic malignancies in transplanted mice. The molecular basis of HOXB4-mediated benign HSC expansion in vivo is not well understood. To gain further insight into the molecular events underlying HOXB4-mediated HSC expansion, we analyzed gene expression changes at multiple time points in Lin-Sca1+c-kit+ (LSK) cells from mice transplanted with bone marrow (BM) cells transduced with a MSCV-HOXB4-ires-YFP vector. A distinct HOXB4 transcriptional program was reproducibly induced and stabilized by 12 weeks after transplant. Dynamic expression changes were observed in genes critical for HSC self- renewal as well …

An Examination Of The Instability And Exploitation In Congo From King Leopold Ii's Free State To The 2nd Congo War, Baldwin Beal

HIM 1990-2015

This thesis will analyze the Congo from King Leopold II's Free State to the 2nd Congo War. After a thorough investigation of the colonial period, this thesis will analyze the modern period. This thesis contends that the underdevelopment of the Congo, and its continuing warfare and poverty are the consequences of an exploitative colonial history. To be sure, King Leopold II of Belgium created the template for administering the Congo through the installation of concessionary companies that were more interested in harvesting huge profits than creating the conditions for a self-sustaining Congolese economy. Indeed, the policies implemented by King Leopold …

An Empire On The Brink Of Destruction: The Stability Of The Seleucid Empire Under Antiochus Iv (175 B.C. - 164 B.C.), Tyler Campbell

HIM 1990-2015

The Seleucid Empire expanded its territory to stretch from Thrace to India under the leadership of Antiochus III, making it one of the most expansive empires in the Hellenistic World. Antiochus III's subsequent loss at the Battle of Magnesia to Rome in 190 B.C. caused some of the satrapies of the empire to begin to rebel, and has led some historians to believe that the empire began an unrecoverable decline. In this investigation I will argue that the myth of decline in the post-Antiochus III era is invalid through analyzing the stability brought to the empire during the reign of …

Libertarian, Liberal, And Socialist Concepts Of Disributive Justice, Daniel Kassebaum

HIM 1990-2015

What makes for a just society constitutes one of the most intensely debated subject among political philosophers. There are many theorists striving to identify principles of justice and each believes his/hers theory to be the best. The literature on this subject is much too voluminous to be canvassed in its entirety here. I will, however, examine the stances and arguments of three key schools of thought shaping the modern discussion of social justice: libertarianism (particularly Robert Nozick and Milton and Rose Friedman), liberal egalitarianism (John Rawls and Ronald Dworkin), and socialism (Karl Marx and John Roemer). Each of these schools …

Madama Butterfly: The Mythology; Or How Imperialism And The Patriarchy Crushed Butterfly's Wings, Adriana Nieves

HIM 1990-2015

As a popular historic work with constant and worldwide performances, the sexist and racist narratives disseminated by Giacomo Puccini's opera Madama Butterfly causes harmful social and political ramifications. Many scholars point to this opera specifically when discussing the fetishization of Asian females, and mention the title character as the quintessential example of damaging stereotypes. Thus, I conduct a postcolonial and feminist reading of Madama Butterfly, through analysis of the opera's libretto, the libretto sources, and the opera's score. I unravel the Orientalist assumptions that make up the foundation of the Butterfly narrative, and trace them as they make their way …

Elementary Pre-Service Teachers' Perceptions Of Thematic Unit Instruction Versus Single-Subject Instruction, Shana Shea

HIM 1990-2015

The focus of this research project was to determine whether thematic unit instruction or traditional, single-subject instruction was perceived to be the more effective and engaging way of teaching as decided by pre-service teachers. Research has shown that incorporating multiple subjects into one unit or topic of study helps to create more engagement and connections to which students can relate. In creating these connections, students can relate the content to their real life and in turn, better comprehend and retain the material. The pre-service teachers attend the University of Central Florida's College of Education and Human Performance. They voluntarily participated …

Classifying Corruption, Yasmin Dawood

Duke Journal of Constitutional Law & Public Policy

No abstract provided.

The Unified-Fft Method For Fast Solution Of Integral Equations As Applied To Shielded-Domain Electromagnetics, Brian J. Rautio

Dissertations - ALL

Electromagnetic (EM) solvers are widely used within computer-aided design (CAD) to improve and ensure success of circuit designs. Unfortunately, due to the complexity of Maxwell's equations, they are often computationally expensive. While considerable progress has been made in the realm of speed-enhanced EM solvers, these fast solvers generally achieve their results through methods that introduce additional error components by way of geometric approximations, sparse-matrix approximations, multilevel decomposition of interactions, and more. This work introduces the new method, Unified-FFT (UFFT). A derivative of method of moments, UFFT scales as O(N log N), and achieves fast analysis by the unique combination of …

An Evaluation Of The Effectiveness Of E-Learning, Mobile Learning, And Instructor-Led Training In Organizational Training And Development, Tyechia Paul

College of Business and Economics

Employee training is a strategic investment. While workforce training has depended on traditional, face-to-face, classroom delivery, new methods have emerged. Electronic learning (e-learning) is training via electronic medium. Mobile learning (m-learning) is a subset of e-learning modalities and specifically refers to electronic delivery of training via mobile devices such as smartphones, tablets, and laptops. The new generation of e-learning is delivered in a mobile environment. Yet, there has been little research to establish the efficacy of the newer training methods.

This study was among the first to fill this research gap through an experiment that tested the comparative effectiveness of …

The Effects Of Ipad Apps On Student Achievement In Literacy For Children In 2nd And 3rd Grade, Deena M. Reyes

Dissertations, Masters Theses, Capstones, and Culminating Projects

Many educators consider using educational iPad apps to supplement literacy curriculum and facilitate greater student engagement. Student literacy achievement is crucial at the lower elementary level. Students who do not progress through the grade level literacy standards of the Common Core State Standards need intervention instruction to achieve mastery. The purpose of this paper is to examine the effectiveness of using iPad apps based instruction in reading intervention programs for second and third grade students.

This study followed a mixed method approach, a pretest, post-test quasi experimental design where students enrolled in an after school reading intervention program used iPad …

Research: South Dakota State University, Winter 2014, Christie Delfanian, Eric Landwehr

State of Discovery South Dakota State University's Research Magazine

CONTENTS:

Weeds influence gene expression, growth in corn [Page] 2
Graduate research targets childhood obesity [Page] 3
Transmammary drug delivery system for early-stage breast cancer may reduce side effects [Page] 5
Biochemical pathways may be key to scab resistance [Page] 7
New filtration system saves water, money for City of Sioux Falls [Page] 8
Doulas ease stress, increase satisfaction with the birthing experience [Page] 9
Structure lab evaluates strength, durability of structural components [Page] 10
Device gives sunflower producers reprieve from combine fires [Page] 12
Graduate scholarship winner works on renewable energy storage [Page] 12

Wildlife Deterrence Method Test Device, Garrett Tietz, Adam Webb, Dane Knutson

Mechanical Engineering

The objective of the Deer Busters team is to design and build a device or system of devices that will be used to determine which method, or methods, are most effective at deer deterrence. JumpSport suspects that a method which gives the appearance of approach to the deer in an aggressive or startling manner but also changes the way it attacks so that the deer do not get used to the device will be most effective. Deer Busters is committed to the completion of the deer deterrent testing device by the end of the fall quarter of 2014.

The Influences Of Brand-Consumer And Cause-Congruence On Consumer Responses To Cause Related Marketing, Ronald E. Goldsmith, Zhu Yimin

Journal of Applied Marketing Theory

Cause Related Marketing (CRM) is a widely used type of brand alliance in which companies donate a portion of their sales to social causes with whom they ally. Researchers have studied many aspects of CRM to learn why these programs are effective and how to enhance their success. An overlooked component in CRM research is the extent to which consumers identify with the brand and with the cause. The present study presented 604 U.S. college students with CRM campaigns for two brands (M&Ms and Crest) partnered with the World Wildlife Fund to assess whether brand-cause congruence, brand-consumer congruence, cause-consumer congruence, …

An Examination Of The Effects Of Atorvastatin And Parathyroid Hormone On Osteoblast Activity, Inlok Lam, Andrea Traina, Melinda E. Lull

Doctoral External Publications

HMG-CoA reductase inhibitors, also known as statins, are a ubiquitous class of medication used for lowering cholesterol. In-vitro and animal studies have suggested that statins can activate osteoblast differentiation and have anabolic effects on bones; however, observational and experimental studies in humans have shown conflicting results.1-5 The exact mechanism of statins on bone growth is unknown; however, there are several hypotheses. The “Lipid Hypothesis” (Figure 1) suggests that lipid oxidation leads to activation of PPARγ, and production of isoprostanes including isoPGF2α and isoPGEα. PPARγ is associated with inhibition of osteoblast differentiation, while isoprostanes markers are associated with the induction of …

Docam 2014 Founders Lecture: Photocutionary Acts, Selfies And Public Knowledge, Brian C. O'Connor

Proceedings from the Document Academy

This paper is drawn from the DOCAM 2014 Founders Lecture Selfies and Public Knowledge: DOCAM 2014 Founders Lecture, "Selfies and Public Knowledge: Technology & Situational Documents"

Ecological, Physiological, And Molecular Characterization Of Annual Bluegrass (Poa Annua L.) Herbicide Resistance And Its Control On Golf Courses, Robert Cross

All Dissertations

Annual bluegrass (Poa annua L.) is one of the most pervasive, adaptable, and variable plant species in the world and is the most problematic winter annual weed in managed turfgrass. Its prolific seedhead production regardless of mowing height, clumping growth habit, and lack of tolerance to stress reduces turfgrass aesthetic quality and playability on golf courses. Its ability to germinate almost year-round influences cultural practices and herbicide use. Herbicides are an integral part of a weed control program for all weeds that invade a desirable turfgrass stand. However, inappropriate use of herbicides results in herbicide resistance issues. In recent years, …

Immigrants And Cultural Continuance In The Liturgy: Celebrating The Nigerian Igbo Mass In The United States, M. Reginald Anibueze D.D.L.

Journal of the Black Catholic Theological Symposium

The dynamics of the celebration of the Igbo Mass in the United States reveals a cultural nostalgia inherent among Igbo immigrants, one that aims at preserving the Igbo identity and culture, even in the diaspora. Convinced to maintain their cultural heritage on foreign soil, Nigerian Igbo Catholic immigrants established faith communities where liturgical worship is performed and expressed in ways that are consistent and meaningful to Igbo indigenous ways of worship. This essay studies the liturgical life of Nigerian Igbo Catholics in the United States, and how a people's cultural and religious heritage is preserved, sustained, and promoted in the …

The Black Community And The Call For Vatican Council Ii (1962-1965), Kathleen Dorsey Bellow

Journal of the Black Catholic Theological Symposium

Even as the Church celebrates the 50th anniversary of Vatican Council II (1962-65), the people of God have not unfolded much of its meaning for Catholic pastoral practice and teaching. In the excitement of Council developments, many updates were implemented in the life of the church without proper catechesis, leaving many of the faithful – proponents and opponents of the Council - wholly uninformed about the continuity of Council reforms with Catholic tradition. The dialogue between the Church and contemporary society formally endorsed in Vatican II is ongoing. A review of the world’s situation in the 1950s and 60s provides …

Building A Story Together: The Challenge Of Conversion In A Plural Age; A Narrative Interpretation, Nathaniel Samuel

Journal of the Black Catholic Theological Symposium

If Christian conversion is understood as conversion-in-history, then how does our present culture of fear, distrust and indifference to the ‘other’ animate discipleship as an ongoing process of conversion? This essay develops a narrative hermeneutic as a viable conceptual and theological framework for engaging this question. Describing the conversion process as an unfolding story of our lived “yes” to God’s self-gift, it argues that saying “yes” to God today means, among other things, welcoming the (often demanding) story of the other. The “yes” of conversion entails nurturing a narrative hospitality. The essay offers two ways to practice a spatially and …

Review: 'More Desired Than Our Owne Salvation: The Roots Of Christian Zionism', William Vance Trollinger

History Faculty Publications

The degree of American “affinity with the State of Israel,” to use Robert O. Smith’s language in his enlightening book, is simply remarkable. As Smith documents, polling results over the last few decades make abundantly clear that American Christians — led by white evangelicals — consistently and overwhelmingly side with Israelis and against Palestinians. Regarding U.S. policies in the Middle East, while polls show that a majority of people throughout the rest of the world — including, as revealed in a 2003 poll, Israelis themselves — believe that American foreign policy is unfairly tilted toward Israel, Americans maintain that U.S. …

Vascular Reactivity In Newly-Formed And Mature Arterialized Collateral Capillaries, Sara K. Hellstrom

Master's Theses

Peripheral arterial occlusive disease (PAOD) is a globally-prevalent cardiovascular disease in which atherosclerotic plaques narrow arterial lumen diameters and restrict blood flow to downstream tissues. The impact of these occlusions can be mitigated by collateral vessels that connect parallel arterial branches and act as natural bypasses to maintain perfusion. In animal models that lack collateral arterioles, capillaries that connect terminal arteriolar segments can arterialize and form functional collaterals following an ischemic event; however, in the early stages of development, vasodilation is impaired. We explored the mechanism of impaired vasodilation in arterialized collateral capillaries (ACCs) and pre-existing collaterals (PECs) by evaluating …

Gene Electro Transfer Of Plasmid Encoding Vascular Endothelial Growth Factor For Enhanced Expression And Perfusion In The Ischemic Swine Heart, Barbara Y. Hargrave, Robert Strange Jr., Sagar Navare, Michael Stratton, Niculina Burcus, Len Murray, Cathryn Lundberg, Anna A. Bulysheva, Fanying Li, Richard Heller

Bioelectrics Publications

Myocardial ischemia can damage heart muscle and reduce the heart's pumping efficiency. This study used an ischemic swine heart model to investigate the potential for gene electro transfer of a plasmid encoding vascular endothelial growth factor for improving perfusion and, thus, for reducing cardiomyopathy following acute coronary syndrome. Plasmid expression was significantly greater in gene electro transfer treated tissue compared to injection of plasmid encoding vascular endothelial growth factor alone. Higher gene expression was also seen in ischemic versus non-ischemic groups with parameters 20 Volts (p

Risk And Emergency Communications: How To Be Heard When The Message Counts Most, Heather N. Kolich

Journal of Extension

To cope with disasters and emergencies, agricultural producers need specific information addressing livestock care, disease containment, secure storage of volatile chemicals, and other unique concerns. Effective risk and emergency communications result from a time- and resource-intensive process that begins well before emergencies occur. To influence our agricultural clients to engage in risk-mitigation and emergency-preparedness behaviors, Extension agents must build trust with the community, provide information through a variety of channels, and convey an image of professional emergency response competency.

Three Steps Forward: Shared Regulatory Space, Deference, And The Role Of The Court, Amanda Shami

Fordham Law Review

When a party files suit challenging the legitimacy of an agency’s interpretation of its governing statute, Chevron U.S.A. Inc. v. Natural Resources Defense Council, Inc. instructs courts to defer to the agency’s interpretation where (1) the court has found that Congress had not foreclosed the agency’s interpretation, and (2) the agency’s interpretation was a reasonable or permissible exercise of its authority. However, sometimes Congress enacts statutes delegating authority over a given regulatory space to more than one agency. When two agencies have shared authority under the same regulatory scheme, those agencies may disagree regarding the interpretation of certain provisions that …

Rediscovering Trespass: Towards A Regulatory Approach To Defining Fourth Amendment Scope In A World Of Advancing Technology, Martin R. Gardner

Buffalo Law Review

No abstract provided.

Identifying Topographic Controls Of Terrestrial Vegetation Using Remote Sensing Data In A Semiarid Mountain Watershed, Idaho, Usa, Ricci Loughridge

Boise State University Theses and Dissertations

Global climate change is a significant research focus area in contemporary Earth science. Changes in climatic patterns have already resulted in shifting energy flows with associated changes in hydrologic and ecologic systems. More specifically, changes in vegetation distribution and abundance are one of the most visible and potentially significant effects of a changing climatic regime. However, to monitor and predict future changes in vegetation, the initial conditions must be well characterized. This thesis examines the distribution of vegetation in a semiarid mountain watershed in three important ways: (1) quantifying the factors affecting the distribution of broad classes of vegetation at …

Between Access And Influence: Building A Record For The Next Court, Renata E. B. Strause, Daniel P. Tokaji

Duke Journal of Constitutional Law & Public Policy

No abstract provided.

Passive Takings: State Inaction And The Duty To Protect Property, Christopher Serkin

Vanderbilt Law School Faculty Publications

As conventionally understood, regulatory takings doctrine protects property owners from the most significant costs of legal transitions. Legal change has therefore always been central to regulatory takings claims. This Article argues that it does not need to be, and that governments can violate the Takings Clause by failing to act in the face of a changing world. This is much more than a minor refinement of takings law because government liability for failing to act means that, in at least some circumstances, the Takings Clause imposes an affirmative obligation on the government to protect property. This liability runs counter to …

Changing Lead Into Gold: Examining Agency Attempts To Use The Clean Water Act To Solve Ecosystem Degradation Issues, N. Lindsay Simmons

William & Mary Environmental Law and Policy Review

No abstract provided.