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2013

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Photothermal Desorption Of Toluene From Single Walled Carbon Nanotube And Activated Carbon Sorbents, Evan Lee Floyd Jan 2013

Photothermal Desorption Of Toluene From Single Walled Carbon Nanotube And Activated Carbon Sorbents, Evan Lee Floyd

All ETDs from UAB

Millions of workers are occupationally exposed to volatile organic compounds (VOC) annually, requiring exposure assessments through air sampling. Reducing time to knowledge while maintaining adequate sensitivity and affordability is a constant struggle. Sorbent sampling is the preferred technique for VOC exposure assessments. Chemical desorption of sorbents is the most common desorption technique, but sensitivity is limited due to the small injection fraction. Thermal desorption has excellent sensitivity, but provides only one analysis per sample and is cost prohibitive. The goal of this dissertation was to develop a desorption technique that bridges the sensitivity gap between chemical desorption (0.1%) and thermal …

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The Development Of An In Vitro Surrogate Assay For Screening Protective Antibodies Against Pneumococcal Surface Protein A (Pspa), Kristopher Ruben Genschmer Jan 2013

The Development Of An In Vitro Surrogate Assay For Screening Protective Antibodies Against Pneumococcal Surface Protein A (Pspa), Kristopher Ruben Genschmer

All ETDs from UAB

PCV13 is the current pneumococcal protein conjugated vaccine made up of the 13 most clinically relevant capsular polysaccharides. While protective, it is limited to a small portion of the overall serotypes of Streptococcus pneumoniae. The possibility of "serotype replacement" by serotypes not covered by the vaccine and the high cost of producing this conjugated polysaccharide vaccine stress the need for a protein based vaccine, one that is more broad in its protection. Pneumococcal surface protein A (PspA) has been shown to be both immunogenic and protective in mice and is a promising protein vaccine candidate. However, there are no current …

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Predictors Of Physical Activity In Child And Adolescent Survivors Of Cancer, Margaux Barnes Gilliam Jan 2013

Predictors Of Physical Activity In Child And Adolescent Survivors Of Cancer, Margaux Barnes Gilliam

All ETDs from UAB

Childhood cancer survivors are at increased risk for future health problems. As such, physical activity (PA) has been targeted as a health promotion priority in child and adolescent cancer survivors. Despite research suggesting PA has protective health benefits, a large proportion of survivors do not meet PA recommendations. Development of effective interventions to increase PA in pediatric cancer survivors requires an understanding of the processes that determine survivor PA. Research on the determinants of PA in child and adolescent survivors is sparse, with most research focusing on late adolescent, young adult, and adult survivors of childhood cancer. The following papers …

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Suicide And Eating Disorders: The Role Of Religiosity, Spirituality And Religious Coping Style, Natalie Goodwin Jan 2013

Suicide And Eating Disorders: The Role Of Religiosity, Spirituality And Religious Coping Style, Natalie Goodwin

All ETDs from UAB

Suicide is a leading cause of death in persons diagnosed with an eating disorder. Religious factors have been demonstrated to be protective against many negative outcomes, including suicidality. Research has demonstrated that religious factors may be important in both the development and treatment of an eating disorder. The present study examines whether religiosity, spirituality, positive and negative religious coping style are protective against suicidal ideation and retrospective report of suicide attempts. The study included 91 mostly White, female participants from a residential treatment center for eating disorders. Participants were diagnosed with either anorexia nervosa (AN), bulimia nervosa (BN) or eating …

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Eye Gaze Patterns During Live Social Interactions In Children With Autism Spectrum Disorders, Michael Warren Gower Jan 2013

Eye Gaze Patterns During Live Social Interactions In Children With Autism Spectrum Disorders, Michael Warren Gower

All ETDs from UAB

Children with autism have been shown to demonstrate deficits in their facial processing skills and are known to make less eye contact than typically developing children. It has also been assumed that children with autism are more anxious during social interactions than typically developing children. It has been hypothesized that these deficits manifest themselves as the use of a localized facial processing style in which children with autism focus primarily on the mouth and miss much of the pertinent social information conveyed by the eyes. More recent research, however, has found contradictory evidence. Specifically, some studies have shown that children …

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Prevalence Of Overweight And Obesity In Classic Rett Syndrome., Kathrine Clova Grigsby Jan 2013

Prevalence Of Overweight And Obesity In Classic Rett Syndrome., Kathrine Clova Grigsby

All ETDs from UAB

Introduction: Rett syndrome (RTT) is a genetic, neurodevelopmental disorder that displays high incidence of growth failure, variations in body composition, feeding/gastrointestinal complications, and undernutrition. The ongoing Rare Diseases Clinical Research Network (RDNCRN) Rett Syndrome Natural History Research Project has yielded observations regarding the less recognized occurrence of overnutrition in adult females with classic Rett syndrome. The purpose of this study was the determine the prevalence of overweight/obesity in children and young adults with classic Rett syndrome, the percent overweight and obese among adults with classic Rett syndrome, and to determine if the prevalence of overnutrition increases after the puberty years …

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The Burden Of Chronic Conditions On Self Reported Health Status In A Medicare Advantage Plan Population, Barbara Ann Guerard Jan 2013

The Burden Of Chronic Conditions On Self Reported Health Status In A Medicare Advantage Plan Population, Barbara Ann Guerard

All ETDs from UAB

THE BURDEN OF CHRONIC CONDITIONS ON SELF REPORTED HEALTH STATUS IN A MEDICARE ADVANTAGE PLAN POPULATION BARBARA GUERARD ADMINISTRATION-HEALTH SERVICES ABSTRACT This dissertation was a multi-staged research study with two goals. The first goal was to assess survey respondents' characteristics to better understand the influence of the characteristics on the validity of self-reported survey responses. Second, the study analyzed the relationship between certain chronic conditions and survey participants' responses to questions related to their overall physical health and mental health to further understand the burden of chronic conditions on self- reported survey responses. Secondary data derived from a patient satisfaction …

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Socioeconomic Status, Social Relationships, And Higher Weight Status, Anthony David Campbell Jan 2013

Socioeconomic Status, Social Relationships, And Higher Weight Status, Anthony David Campbell

All ETDs from UAB

This thesis serves two main research objectives. The first objective is to examine the extent to which higher weight status is patterned by indicators of socioeconomic status. The second objective is to explore the involvement of social relationships in the association between socioeconomic status and weight status. I use a theoretical framework incorporating aspects of fundamental cause theory and insights from the literature on social relationships and health. Data for this study were obtained from the 2003-2008 National Health and Nutrition Examination Survey (n = 3,957). The analytic sample focused on Black and White respondents over the age of 40. …

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Experience-Dependent Synaptic Integration Of Adult-Generated Dentate Granule Cells, Jessica Hotard Chancey Jan 2013

Experience-Dependent Synaptic Integration Of Adult-Generated Dentate Granule Cells, Jessica Hotard Chancey

All ETDs from UAB

The dentate gyrus (DG) contains neural stem cells that continually generate new neurons throughout life. The contribution of adult neurogenesis to hippocampal function is not well understood, but ablation or silencing of adult-generated neurons in the DG disrupts learning and memory, and neurogenesis is altered in many pathologies associated with impaired cognition including Alzheimer's Disease, epilepsy, and schizophrenia. Neurogenesis in the DG is a stepwise process in which neural stem cells leave the cell cycle and undergo an approximately two month long maturation process to form fully functional dentate granule cells (GCs) that are indistinguishable from those formed during development. …

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Targeting Ovarian Cancer Through Epigallocatechin Gallate And Sulforaphane Combinational Treatment, Huaping Chen Jan 2013

Targeting Ovarian Cancer Through Epigallocatechin Gallate And Sulforaphane Combinational Treatment, Huaping Chen

All ETDs from UAB

The cellular development of resistance to chemotherapy contributes to the high mortality noted in patients affected by ovarian cancer. Novel compounds that can enhance efficacy of conventional chemotherapy or target both drug-sensitive and -resistant ovarian cancers directly are highly desired. Previous epidemiological studies indicate that consumption of green tea and cruciferous vegetables is inversely associated with occurrence of ovarian cancer. Therefore, revealing the effects and mechanisms of major components of green tea (epigallocatechin gallate, EGCG) and cruciferous vegetables (sulforaphane, SFN) on ovarian cancer cells will provide necessary knowledge for developing potential novel treatments for the disease. Since drug resistance generation …

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Hospital Financial Performance: A Look At Governance And Hit Strategies, Taleah Collum Jan 2013

Hospital Financial Performance: A Look At Governance And Hit Strategies, Taleah Collum

All ETDs from UAB

Taken together, the purpose of the three papers included in this dissertation is to provide empirical evidence on the relationship between strategies employed by hospital managers and hospital financial performance. The findings of these studies are important to managers as they search for ways to sustain and improve hospital financial performance in light of environmental changes that have taken place over the last three decades. The results of this dissertation suggest that to improve financial performance hospital leaders (e.g. management, board of directors) should choose strategies that are more amenable to their control. Specifically, having BOD members that are independent …

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Cortical Thickness In Amnestic Mild Cognitive Impairment And Its Relationships With Neuropsychological Functioning And Financial Capacity, Jacquelynn Nicosia Copeland Jan 2013

Cortical Thickness In Amnestic Mild Cognitive Impairment And Its Relationships With Neuropsychological Functioning And Financial Capacity, Jacquelynn Nicosia Copeland

All ETDs from UAB

Diagnostic criteria for amnestic mild cognitive impairment (aMCI) include subjective memory complaint, objective memory impairment, preserved general cognitive function, intact functional abilities, and absence of dementia diagnosis (Petersen, 2004). However, there is evidence to suggest that some aMCI patients show declines in complex instrumental activities of daily living. Under the conceptual model proposed in this study, neuropathological changes occurring in the brain of aMCI and Alzheimer's disease (AD) patients underlie specific forms of neurocognitive dysfunction, which in turn drive decline in everyday functional skills such as financial capacity. The current study examined the relationships between structural brain changes in aMCI, …

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Blood Pressure Control And Perceived Stress, Job Satisfaction, Life Satisfaction, And Perceived Health Status In Municipal Workers, Debra D. Baldwin Jan 2013

Blood Pressure Control And Perceived Stress, Job Satisfaction, Life Satisfaction, And Perceived Health Status In Municipal Workers, Debra D. Baldwin

All ETDs from UAB

Although hypertension is highly prevalent, associated with serious health consequences and treatable, fewer than half of those with hypertension have achieved blood pressure control (Centers for Disease Control and Prevention [CDC], 2011b). Limited studies have examined the influence of perceived stress, job satisfaction, life satisfaction, and perceived health status may have on blood pressure control, although epidemiological evidence reveals psychological factors can mediate and negatively influence health behavior leading to hypertension (Blanchflower & Oswald, 2008; Kulkarni, Farrel, Erasi, & Kochar, 1998; Walcott-McQuigg, 2000). The purpose of this study was to explore the prevalence of hypertension, obesity, and blood pressure control …

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The Relationship Of Maternal Depressive Symptoms Among First Time Adolescent And Adult Mothers And Their Safe Parenting Practices And Child Injuries, Angela Warren Baumann Jan 2013

The Relationship Of Maternal Depressive Symptoms Among First Time Adolescent And Adult Mothers And Their Safe Parenting Practices And Child Injuries, Angela Warren Baumann

All ETDs from UAB

Maternal depressive symptoms have been associated with deficits in parenting practices that protect children from injuries; however, few studies have been conducted to examine these relationships. Using data from a multisite longitudinal study of 252 first-time mothers, the relationships between the use of safe parenting practices and maternal depressive symptoms was examined, taking into account mother's resources (as defined by age and education level) and race at five time points during the first 3 years of the child's life. Depressive symptoms were assessed using the Beck Depression Inventory. Measures of maternal depressive symptoms, safe parenting practices (use of car seat, …

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The Molecular Basis Of Male Sex Determination During Temperature-Dependent Sex Determination, Kayla Bieser Jan 2013

The Molecular Basis Of Male Sex Determination During Temperature-Dependent Sex Determination, Kayla Bieser

All ETDs from UAB

The red-eared slider turtle (Trachemys scripta) possesses temperature-dependent sex determination (TSD) in which the incubation temperature of the developing embryo determines gonadal sex. Although a number of mammalian gene homologues have been identified in the sex determination/differentiation cascade of reptiles with TSD, the exact trigger(s) is not well understood. As such, this dissertation research addresses the mRNA expression profiles of putative sex-determining/differentiation genes (Dmrt1, Sox9, Amh, Lhx9, and Foxl2) with an emphasis on the male cascade in embryonic gonads of T. scripta. Additionally, this research addresses the influence of exogenous estrogen and aromatase inhibitors on gene expression. Lastly, this dissertation …

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Resonances And Inverse Scattering, Matthew Bledsoe Jan 2013

Resonances And Inverse Scattering, Matthew Bledsoe

All ETDs from UAB

Inverse scattering problems for Sturm-Liouville differential equations find numerous applications in physics, in particular, quantum mechanics. While the theory of these problems has been developed over a number of decades, a more recent concern has been the use of resonances, important phenomena in physics, as data — the inverse resonance problem. In this dissertation, we address this problem in a variety of cases. First, we investigate the full-line Schroedinger equation where the data for the inverse problem include the eigenvalues and resonances. We prove that any two potentials that have enough data points sufficiently close together must also be close …

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The Role Of Il-21 And Il-17 In Regulating Follicular T Helper Cells In Germinal Center Response Of Autoimmunity, Yanna Ding Jan 2013

The Role Of Il-21 And Il-17 In Regulating Follicular T Helper Cells In Germinal Center Response Of Autoimmunity, Yanna Ding

All ETDs from UAB

Overreactivity of the germinal center (GC) is a central feature of autoantibody-mediated autoimmune diseases. Follicular T helper (Tfh) cells are the primary T helper subset that migrates to the incipient GC and forms close contacts with GC-B cells to promote GC formation and help GC-B cell differentiation, resulting in high-affinity antibody production. Increased levels of interleukin (IL)-21 and aberrant accumulation or function of Tfh cells have been associated with autoimmune disease severity in humans and lupus-prone mice. Follicular regulatory T (Tfr) cells are the regulatory T cell subset that also localizes in the GC and inhibits GC B cell differentiation. …

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The Evolution And Phylogeography Of A Glade-Restricted Species Of Prairie Clover (Dalea Cahaba J. Allison) From Bibb County, Alabama: A Molecular Approach, James Diggs Jan 2013

The Evolution And Phylogeography Of A Glade-Restricted Species Of Prairie Clover (Dalea Cahaba J. Allison) From Bibb County, Alabama: A Molecular Approach, James Diggs

All ETDs from UAB

The Cahaba prairie clover (Dalea cahaba) is one of eight species endemic to the dolomitic glades of Bibb County, Alabama. The evolutionary history of this species is currently unknown. This study tests the hypothesis that the species is a result of adaptive radiation from a widespread congener. The phylogenetic histories of several eastern species of Dalea are reconstructed using two genes that have previously been informative in plant molecular systematic studies: the internal transcribed spacer (ITS) and the matK gene. Morphological similarities between D. cahaba and a Texas-endemic species, D. tenuis, have prompted questions of whether similar traits imply common …

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Development Of Skin Hypopigmentation In A Patient With Metastatic Papillary Carcinoma Thyroid Treated With Sorafenib., Syed Zubair Hussain, Ali Asghar, Mubasher Ikram, Najmul Islam Jan 2013

Development Of Skin Hypopigmentation In A Patient With Metastatic Papillary Carcinoma Thyroid Treated With Sorafenib., Syed Zubair Hussain, Ali Asghar, Mubasher Ikram, Najmul Islam

Section of Otolaryngology, Head & Neck Surgery

Background: Sorafenib can be considered as the effective option of treatment in patients with metastatic radioiodine refractory differentiated thyroid cancers. The cutaneous manifestations of Sorafenib include rash, desquamation, hand foot skin reactions, pruritus, alopecia and erythema. We report the first case of hypopigmentation related to sorafenib therapy. Case presentation: We report the case of a middle aged gentleman with metastatic papillary carcinoma of thyroid diagnosed in 2005. He was managed with total thyroidectomy, radioactive iodine and TSH suppressive therapy. Despite receiving radioactive iodine 530 mci cumulative dose, patient had persistant disease with lung metastasis. Therefore a TKI, sorafenib, was started. …

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Tuberculosis Verrucosa Cutis In A Patient With Keloid Over Ear Lobule, Muhammad Sohail Halim, Sadaf Qadeer Ahmed, Montasir Junaid, Muhammad Rizwan Bashir Jan 2013

Tuberculosis Verrucosa Cutis In A Patient With Keloid Over Ear Lobule, Muhammad Sohail Halim, Sadaf Qadeer Ahmed, Montasir Junaid, Muhammad Rizwan Bashir

Section of Otolaryngology, Head & Neck Surgery

Tuberculosis (TB) is a global health problem with predominance in resource-poor countries. Extrapulmonary TB constitutes approximately 10% of the cases and can present as different forms depending on the route of entry. Cutaneous TB is a small subset of the extrapulmonary TB. Cutaneous TB can either be of primary origin or secondary origin or it can be a part of a systemic infection. TB verrucosa cutis (TBVC) is the exogenous reinfection of TB in a previously sensitised patient. Routine cultures do not have a high yield in TBVC due to the paucibacillary nature of the organism. Here we are presenting …

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Harnessing The Power Of The Grassroots To Conduct Public Health Research In Sub-Saharan Africa: A Case Study From Western Kenya In The Adaptation Of Community-Based Participatory Research (Cbpr) Approaches, Allan Kamanda, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Peter Gisore, Samuel Ayaya, Rachel Vreeman, Paula Braitstein Jan 2013

Harnessing The Power Of The Grassroots To Conduct Public Health Research In Sub-Saharan Africa: A Case Study From Western Kenya In The Adaptation Of Community-Based Participatory Research (Cbpr) Approaches, Allan Kamanda, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Peter Gisore, Samuel Ayaya, Rachel Vreeman, Paula Braitstein

Internal Medicine, East Africa

Background: Community-based participatory research (CBPR) is a collaborative approach to research that involves the equitable participation of those affected by an issue. As the field of global public health grows, the potential of CBPR to build capacity and to engage communities in identification of problems and development and implementation of solutions in sub-Saharan Africa has yet to be fully tapped. The Orphaned and Separated Children’s Assessments Related to their Health and Well-Being (OSCAR) project is a longitudinal cohort of orphaned and non-orphaned children in Kenya. This paper will describe how CBPR approaches and principles can be incorporated and adapted into …

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Neural Substrates That Mediate Learning-Related Changes In The Emotional Response To A Threat, Joshua Richard Shumen Jan 2013

Neural Substrates That Mediate Learning-Related Changes In The Emotional Response To A Threat, Joshua Richard Shumen

All ETDs from UAB

Recognizing cues that predict a threat allows one to react more effectively under threatening conditions, attenuating or potentiating the response to the threat depending on the circumstances. This is demonstrated during Pavlovian fear conditioning when the unconditioned response (UCR) to a predictable unconditioned stimulus (UCS) is diminished compared to the UCR of an unpredictable UCS (Dunsmoor, Bandettini, & Knight, 2008; Wood, Ver Hoef, & Knight, 2012). In the current study skin conductance, electromyography (orbicularis oculi), UCS expectancy, and blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) were assessed during a Pavlovian temporal fear conditioning paradigm. Right-handed volunteers were …

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Determining Whether Sequence Differences In Gfa Gene Cause Alexander Disease, Lital Nehama Silverman Webster Jan 2013

Determining Whether Sequence Differences In Gfa Gene Cause Alexander Disease, Lital Nehama Silverman Webster

All ETDs from UAB

Alexander disease (AxD) is a fatal astrogliopathy usually caused by mutations in the GFA gene, which encodes glial fibrillary acidic protein (GFAP). In this document, two unusual sequence differences in GFA that are associated with AxD are characterized. The first difference is the only reported case of an AxD-causing mutation occurring in a non-coding region of GFA, c.(619-3C>G), resulting in the largest known in-frame deletion in GFAP due to abnormal splicing in a small fraction of the GFA transcripts. The second difference is the farthest reported C-terminal point mutation in GFAP, g.1277A-->T, which produces a Q426L coding change. …

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Progressive Forming Of Thermoplastic Composite Laminates, John Robert Smith Jan 2013

Progressive Forming Of Thermoplastic Composite Laminates, John Robert Smith

All ETDs from UAB

Composite materials display excellent specific strength and stiffness, light-weighting benefits, and are effective replacements for metals which are typically heavy and susceptible to corrosion. Next generation transportation, military, infrastructure, and marine sectors are extensively using fiber reinforced composite materials for part replacement and structural applications. Producing these advanced composite structures can often result in extensive development time and material wastage. There is a need to understand composite laminate formability and implement predictive methodology during product design to minimize manufacturing costs. The overall objective of this research was to predict the formability of thick section, plain woven, thermoplastic matrix composite laminates …

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Ultrasound And Microbubbles: A Role In Cancer, Anna Sorace Jan 2013

Ultrasound And Microbubbles: A Role In Cancer, Anna Sorace

All ETDs from UAB

Successful cancer treatment relies on the sensitivity to monitor cancer response to therapy and the ability to efficiently deliver drugs to the tumor. Cancer research has continuously improved patient outcomes over the last decades; however, it is still the second leading cause of death in the United States. It is essential to improve methods to progress all areas of cancer treatment, including monitoring and drug delivery. Ultrasound (US) is a popular clinical imaging modality due to its low levels of radiation, portability, and cost effective imaging. These advantageous characteristics have allowed for novel research advancements in the US field including …

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The Role Of Gadd45b In Hippocampus-Dependent Cognition, Synaptic Plasticity And Activity-Associated Transcriptional Dynamics, Faraz Sultan Jan 2013

The Role Of Gadd45b In Hippocampus-Dependent Cognition, Synaptic Plasticity And Activity-Associated Transcriptional Dynamics, Faraz Sultan

All ETDs from UAB

An expanding body of literature argues for a pivotal role of molecular epigenetic mechanisms in memory. Defined as mechanisms that regulate gene expression in the absence of DNA sequence modifications, these regulate various stages of memory-associated transcription. These phenomena are present at diverse anatomical subregions of the central nervous system (CNS) and regulate corresponding behaviors. Epigenetic mechanisms comprise a unique category of behavioral and physiological modulators because of their potential to modify the cellular phenotype in a stable manner. Hence, epigenetics offers a novel potential solution to a central paradox in memory retention: the finding that most putative molecular substrates …

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Lightweight Data Location Services For Exascale Storage Systems, Zhiwei Sun Jan 2013

Lightweight Data Location Services For Exascale Storage Systems, Zhiwei Sun

All ETDs from UAB

In order to satisfy the storage demands of Exascale computing by 2018 (a stated goal of the US government and the HPC research community), a number of Exascale storage systems have begun to be designed and explored to facilitate application checkpointing and parallel file storage. Nondeterministic storage systems (which weaken the assumptions of Terascale and Petascale predecessors) can provide useful capabilities that are difficult to implement in today's parallel file systems, such as high-performance writes, dynamic load-balancing, enriched flexibility of moving data and creating replicas, and potentially other features. However, locating data and reading data back from nondeterministic storage systems …

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The Role Of O-Glcnacylation In Synaptic Function, Erica Wynette Taylor Jan 2013

The Role Of O-Glcnacylation In Synaptic Function, Erica Wynette Taylor

All ETDs from UAB

O-GlcNAcylation is a dynamic protein posttranslational modification that adds the monosaccharide ß-N-acetylglucosamine (GlcNAc) to specific serine and threonine residues on nucleocytoplasmic proteins. The hippocampus is a part of brain that has been shown to play a crucial role in learning and memory. Hippocampal neurons have high expression of O-GlcNAc transferase and O-GlcNAcase, which catalyze the addition and removal of GlcNAc from proteins respectively. Moreover, synaptic plasticity which is the strengthening or weakening of synaptic function on short- and long-term time scales is believed to be a cellular correlate of learning and memory. Several forms of synaptic plasticity have been characterized …

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Mid - Infrared Solid State Lasers For Spectroscopic Applications, Yuri Terekhov Jan 2013

Mid - Infrared Solid State Lasers For Spectroscopic Applications, Yuri Terekhov

All ETDs from UAB

This work is devoted to study of novel high power middle-infrared (Mid-IR) laser sources enabling development of portable platform for sensing of organic molecules with the use of recently discovered Quartz Enhanced Photo Acoustic Spectroscopy (QEPAS). The ability to detect small concentrations is beneficial to monitor atmosphere pollution as well for biomedical applications such as analysis of human breath to detect earlier stages of cancer or virus activities. A QEPAS technique using a quartz tuning fork (QTF) as a detector enables a strong enhancement of measured signal when pump laser is modulated with a frequency coinciding with a natural frequency …

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Understanding The Predictors Of Patient Trust And Its Role In Utilization And Outcomes, Sheikilya Lewis Thomas Jan 2013

Understanding The Predictors Of Patient Trust And Its Role In Utilization And Outcomes, Sheikilya Lewis Thomas

All ETDs from UAB

The purpose of this dissertation is to examine patient-related factors that predict trust in one's physician, and subsequently identify the role of patient trust in health care utilization and clinical outcomes among African Americans with hypertension. Three separate studies are conducted using an adapted version of the Interaction Model for Client Health Behavior (IMCHB). The first paper is a three-step review of quantitative studies investigating the (a) patient characteristics that influence trust; (b) impact of trust on health care utilization; and (c) impact of trust on outcomes. Based on the predictors identified, the second study examines the significance of these …

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