Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2013

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 301 - 330 of 29556

Full-Text Articles in Entire DC Network

Hotline Press Newspaper- December 2013 Vol 29 No 32, Hotline Press Newspaper Dec 2013

Hotline Press Newspaper- December 2013 Vol 29 No 32, Hotline Press Newspaper

Hotline Press Newspaper 2013

No abstract provided.


Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Jim Bakken Dec 2013

Newly Identified Immune Receptor May Activate B Cells In Autoimmunity, Jim Bakken

Browse All News

No abstract provided.


Water Vapor Movement In Freezing Aggregate Base Materials, Maile Anne Rogers Dec 2013

Water Vapor Movement In Freezing Aggregate Base Materials, Maile Anne Rogers

Theses and Dissertations

The objectives of this research were to 1) measure the extent to which water vapor movement results in water accumulation in freezing base materials; 2) evaluate the effect of soil stabilization on water vapor movement in freezing base materials; 3) determine if the corresponding changes in water content are sufficient to cause frost heave during winter; 4) determine if the corresponding changes in water content are sufficient to cause reductions in stiffness during spring; 5) evaluate relationships between selected material properties, freezing conditions, and the occurrence and impact of water vapor movement; and 6) numerically simulate heat and water movement …


Mechanisms Of Dietary Protein-Induced Changes In Calcium Absorption Efficiency, Jessica D. Bihuniak Dec 2013

Mechanisms Of Dietary Protein-Induced Changes In Calcium Absorption Efficiency, Jessica D. Bihuniak

Doctoral Dissertations

We undertook a randomized, double-blind, crossover study in 14 healthy women who were required to ingest a 6-day low protein diet supplemented with CaSR-AAA (calcium-sensing receptor-activating amino acids), DAA (dibasic amino acids) or methylcellulose capsules (control). All subjects ingested all three diets in random order. Prior to each experimental diet subjects consumed an 11 day adjustment diet. Calcium absorption was measured on day 5 of each dietary intervention using dual-stable calcium isotopes. The clinical trial tested the hypothesis that dietary protein affects the efficiency of intestinal calcium absorption by activating the calcium sensing receptor (CaSR). Supplementation with CaSR-AAA did not …


Collective Modes In Light Nuclei From First Principles, T. Dytrych, K. D. Launey, J. P. Draayer, P. Maris, J. P. Vary, E. Saule, U. Catalyurek, M. Sosonkina, D. Langr, M. A. Caprio Dec 2013

Collective Modes In Light Nuclei From First Principles, T. Dytrych, K. D. Launey, J. P. Draayer, P. Maris, J. P. Vary, E. Saule, U. Catalyurek, M. Sosonkina, D. Langr, M. A. Caprio

Faculty Publications

Results for ab initio no-core shell model calculations in a symmetry-adapted SU(3)-based coupling scheme demonstrate that collective modes in light nuclei emerge from first principles. The low-lying states of Li6, Be8, and He6 are shown to exhibit orderly patterns that favor spatial configurations with strong quadrupole deformation and complementary low intrinsic spin values, a picture that is consistent with the nuclear symplectic model. The results also suggest a pragmatic path forward to accommodate deformation-driven collective features in ab initio analyses when they dominate the nuclear landscape. © 2013 American Physical Society.


Best In Class Dec 2013

Best In Class

News Releases

No abstract provided.


Emu Today, December 18, 2013, Eastern Michigan University Dec 2013

Emu Today, December 18, 2013, Eastern Michigan University

EMU Today

No abstract provided.


On The Origin Of Phenotypic Variation: Novel Technologies To Dissect Molecular Determinants Of Phenotype, Francesco Vallania Dec 2013

On The Origin Of Phenotypic Variation: Novel Technologies To Dissect Molecular Determinants Of Phenotype, Francesco Vallania

All Theses and Dissertations (ETDs)

This thesis describes the conception, design, and development of novel computational tools, theoretical models, and experimental techniques applied to the dissection of molecular factors underlying phenotypic variation. The first part of my work is focused on finding rare genetic variants in pooled DNA samples, leading to the development of a novel set of algorithms, SNPseeker and SPLINTER, applied to next-generation sequencing data. The second part of my work describes the creation of a reporter system for DNA methylation for the purpose of dissecting the genetic contribution of tissue-specific patterns of DNA methylation across the genome. Finally the last part of …


Volume 51, Number 18: December 18, 2013, University Of North Dakota Dec 2013

Volume 51, Number 18: December 18, 2013, University Of North Dakota

University Letter Archive

No abstract provided.


Divergent Antibody Subclass And Specificity Profiles But Not Protective Hla-B Alleles Are Associated With Variable Antibody Effector Function Among Hiv-1 Controllers, Jennifer I. Lai, Anna F. Licht, Anne-Sophie Dugast, Todd Suscovich, Ickwon Choi, Chris Bailey-Kellogg, Galit Alter, Margaret E. Ackerman Dec 2013

Divergent Antibody Subclass And Specificity Profiles But Not Protective Hla-B Alleles Are Associated With Variable Antibody Effector Function Among Hiv-1 Controllers, Jennifer I. Lai, Anna F. Licht, Anne-Sophie Dugast, Todd Suscovich, Ickwon Choi, Chris Bailey-Kellogg, Galit Alter, Margaret E. Ackerman

Dartmouth Scholarship

Understanding the coordination between humoral and cellular immune responses may be the key to developing protective vaccines, and because genetic studies of long-term HIV-1 nonprogressors have associated specific HLA-B alleles with spontaneous control of viral replication, this subject group presents an opportunity to investigate relationships between arms of the adaptive immune system. Given evidence suggesting that cellular immunity may play a role in viral suppression, we sought to determine whether and how the humoral immune response might vary among controllers. Significantly, Fc-mediated antibody effector functions have likewise been associated with durable viral control. In this study, we compared the effector …


The Murray Ledger And Times, December 18, 2013, The Murray Ledger And Times Dec 2013

The Murray Ledger And Times, December 18, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.


Battery Energy Storage Systems To Mitigate The Variability Of Photovoltaic Power Generation, Heath Alan Gurganus Dec 2013

Battery Energy Storage Systems To Mitigate The Variability Of Photovoltaic Power Generation, Heath Alan Gurganus

Dissertations and Theses

Methods of generating renewable energy such as through solar photovoltaic (PV) cells and wind turbines offer great promise in terms of a reduced carbon footprint and overall impact on the environment. However, these methods also share the attribute of being highly stochastic, meaning they are variable in such a way that is difficult to forecast with sufficient accuracy. While solar power currently constitutes a small amount of generating potential in most regions, the cost of photovoltaics continues to decline and a trend has emerged to build larger PV plants than was once feasible. This has brought the matter of increased …


A Dynamic Optimization Framework With Model Predictive Control Elements For Long Term Planning Of Capacity Investments In A District Energy System, Jose Luis Mojica Velazquez Dec 2013

A Dynamic Optimization Framework With Model Predictive Control Elements For Long Term Planning Of Capacity Investments In A District Energy System, Jose Luis Mojica Velazquez

Theses and Dissertations

The capacity expansion of a district heating system is studied with the objective of evaluating the investment decision timing and type of capacity expansion. District energy is an energy generation system that provides energy, such as heat and electricity, generated at central locations and distributed to the surrounding area. The study develops an optimization framework to find the optimal investment schedule over a 30 year horizon with the options of investing in traditional heating sources (boilers) or a next-generation combined heat and power (CHP) plant that can provide heat and electricity. In district energy systems, the investment decision on the …


Which Biomarkers Reveal Neonatal Sepsis?, Kun Wang, Vineet Bhandari, Sofya Chepustanova, Greg Huber, Stephen O′Hara, Corey S. O′Hern, Mark D. Shattuck, Michael Kirby Dec 2013

Which Biomarkers Reveal Neonatal Sepsis?, Kun Wang, Vineet Bhandari, Sofya Chepustanova, Greg Huber, Stephen O′Hara, Corey S. O′Hern, Mark D. Shattuck, Michael Kirby

Publications and Research

We address the identification of optimal biomarkers for the rapid diagnosis of neonatal sepsis. We employ both canonical correlation analysis (CCA) and sparse support vector machine (SSVM) classifiers to select the best subset of biomarkers from a large hematological data set collected from infants with suspected sepsis from Yale-New Haven Hospital's Neonatal Intensive Care Unit (NICU). CCA is used to select sets of biomarkers of increasing size that are most highly correlated with infection. The effectiveness of these biomarkers is then validated by constructing a sparse support vector machine diagnostic classifier. We find that the following set of five biomarkers …


A Content Analysis Of Advertisements In The Fra And Craftsman Magazines, 1908-1916, Kathryn Runyan Dec 2013

A Content Analysis Of Advertisements In The Fra And Craftsman Magazines, 1908-1916, Kathryn Runyan

Theses

The present study used content analysis to examine advertisements appearing in Elbert Hubbard's The Fra and Gustav Stickley's The Craftsman magazines from 1908 through 1916. A total of 599 ads were analyzed to determine what type of advertisements dominated this period and to discover differences in the persuasive and informative appeals used by two creative forces in American business at the beginning of the 20th century, Elbert Hubbard and Gustav Stickley. The purpose of this study is to understand the advertising strategies appearing in The Craftsman and The Fra magazines.


Midcentury Planning In San Juan, Puerto Rico: Rexford Guy Tugwell, Henry Klumb, And Design For "Modernization", Linda Levin Moreen Dec 2013

Midcentury Planning In San Juan, Puerto Rico: Rexford Guy Tugwell, Henry Klumb, And Design For "Modernization", Linda Levin Moreen

Graduate School of Architecture & Urban Design Theses & Dissertations

No abstract provided.


Congress Easily Approves Energy Reform Plan; Pri, Pan Majorities Key To Passage, Carlos Navarro Dec 2013

Congress Easily Approves Energy Reform Plan; Pri, Pan Majorities Key To Passage, Carlos Navarro

SourceMex

No abstract provided.


Students With Blindness Explore Chemistry At ‘Camp Can Do’, Cary A. Supalo, H. David Wohlers, Jennifer R. Humphrey Dec 2013

Students With Blindness Explore Chemistry At ‘Camp Can Do’, Cary A. Supalo, H. David Wohlers, Jennifer R. Humphrey

Journal of Science Education for Students with Disabilities

Students with blindness or low vision are often discouraged from full participation in laboratory science classes due to the inadequacy of current methodological approaches and the lack of sophisticated adaptive technologies. Consequently, these students rarely go on to pursue advanced studies and employment in the sciences. In response to his own frustrations as a scientist with blindness, Supalo conceived, co-founded, and managed the Independent Laboratory Access for the Blind (ILAB) project for his doctoral research in chemistry. Numerous multisensory tools, technologies, and methodologies for teaching the sciences to students with visual impairments were developed and evaluated by the ILAB team. …


A Program Like Any Other…Like None Other: Sustaining A Laboratory Science Technology Program For Deaf And Hard-Of-Hearing Students, Todd Pagano, Annemarie D. Ross Dec 2013

A Program Like Any Other…Like None Other: Sustaining A Laboratory Science Technology Program For Deaf And Hard-Of-Hearing Students, Todd Pagano, Annemarie D. Ross

Journal of Science Education for Students with Disabilities

A goal of the Laboratory Science Technology program at the National Technical Institute for the Deaf, a college of Rochester Institute of Technology, is to produce graduates with strong foundations in applied science, hands-on laboratory applications, and “soft skills” necessary for competitive employment as laboratory technicians. Graduates of the program earn Associate degrees, and if qualified, transition to related baccalaureate programs. Those who finish either an Associates of Occupational Science or Associates of Applied Science degree programs tend to go to work in the chemical, biological, biotechnology, pharmaceutical, environmental, forensic, industrial, and food analysis fields. At first glance, the LST …


Ambiguity And Inconsistencies In Mathematics Spoken In The Classroom: The Need For Teacher Training And Rules For Communication Of Mathematics, M.D. Isaacson, S. Srinivasan, Lyle Lloyd Dec 2013

Ambiguity And Inconsistencies In Mathematics Spoken In The Classroom: The Need For Teacher Training And Rules For Communication Of Mathematics, M.D. Isaacson, S. Srinivasan, Lyle Lloyd

Journal of Science Education for Students with Disabilities

Mathematics has the potential for being spoken ambiguously. This is problematic for many students, in particular those who have disabilities that inhibit processing of printed material. This paper documents the magnitude of potential ambiguity arising from textbooks and provides a measure of the degree to which potential ambiguity is actualized through teachers’ speech. Inconsistency among teachers in speaking mathematics is also documented. Evidence is provided that teachers are not adequately aware of ambiguity in speaking mathematics and that they believe that they should have training regarding ambiguity in communication of mathematics and how to speak mathematics non-ambiguously.


Engaging Students Through A Virtual Live Case, John M. Zych Dec 2013

Engaging Students Through A Virtual Live Case, John M. Zych

Atlantic Marketing Journal

Students are motivated to engage in their education when they understand how mastery of course content will translate to practical skills needed in the job market. In marketing education, live cases often are used to help students make a clear connection between course content and its application to real-world business problems. There are times, however, when a live case is not feasible or available. For these circumstances, the author has developed an innovative approach which approximates a live case. The approach combines components of a live case with historical analysis to have students perform an in-depth market strategy analysis of …


Parsons To Support Cal Poly Initiative To Produce Future Cybersecurity Professionals, Public Affairs Office Dec 2013

Parsons To Support Cal Poly Initiative To Produce Future Cybersecurity Professionals, Public Affairs Office

Press Releases

No abstract provided.


Reflectance And Ultrastructure Of The Retinal Nerve Fiber Layer In Normal And Glaucomatous Retinas, Ye Spector Dec 2013

Reflectance And Ultrastructure Of The Retinal Nerve Fiber Layer In Normal And Glaucomatous Retinas, Ye Spector

Open Access Dissertations

Glaucomatous damage to the RNFL usually precedes detectable visual field loss; clinical assessment of RNFL optical properties has been valuable in diagnosis of glaucoma and other neuropathic diseases. In this dissertation, we aimed to improve the understanding of the changes of RNFL reflectance and its underlying ultrastructure under the development of glaucoma. We used simultaneous immunohistochemical labeling and both en face and in-depth confocal imaging to study axonal cytoskeletal alteration of F-actin, MTs and NFs across the retina in the context of glaucoma. We have found that alteration of each cytoskeletal components is different from each other, and different degree …


An Inverse Relationship Between Resistance To 2-Deoxy-D-Glucose And Glucose Starvation In Tumor Cells Under Normoxia, Katherine Beth Philips Dec 2013

An Inverse Relationship Between Resistance To 2-Deoxy-D-Glucose And Glucose Starvation In Tumor Cells Under Normoxia, Katherine Beth Philips

Open Access Dissertations

A distinguishing feature of tumor cells is their upregulation of glucose metabolism. This metabolic change from oxidative phosphorylation to aerobic glycolysis creates a selective window that can be exploited for anticancer therapy. Here we investigate mechanisms by which pancreatic cancer cells respond to therapeutic (2-deoxy-D-glucose, 2-DG) and physiologic (glucose starvation, GS) forms of glucose restriction. 2-Deoxy-d-Glucose (2-DG) is a sugar analog of both glucose and mannose and thus has established activities inhibiting glycolysis and interfering with glycosylation, respectively. Due to 2-DG’s dual functions, it has classically been thought of as a glucose deprivation mimetic. Additionally, these roles render 2-DG an …


Order Fitting Policies For Service Systems With Pricing And Inventory Decisions, Salvador Romo-Fragoso Dec 2013

Order Fitting Policies For Service Systems With Pricing And Inventory Decisions, Salvador Romo-Fragoso

Open Access Dissertations

The present work is the foundation for our line of research, looking for policy solutions for: order acceptance, capacity management with interruptions, pricing, and trade-offs between different assets. The first model represents an organization choosing order fitting and pricing policies for a service company selecting between deals and regular jobs with poisson arrivals. The prices for regular jobs are exogenous, whereas winning the deals depends on pricing bids. We derived and compared optimal pricing for two distinct order acceptance policies under a setting where the server had no queue. We investigated the impact of the system parameters on the optimal …


Rewind 2013: An Education Year That Was Unlucky For Some, Louise Holden Dec 2013

Rewind 2013: An Education Year That Was Unlucky For Some, Louise Holden

Media

No abstract provided.


Pcc Quarterly For December 2013, Office Of The President, Rollins College Dec 2013

Pcc Quarterly For December 2013, Office Of The President, Rollins College

PCC Quarterly

No abstract provided.


Plc Quarterly For December 2013, Office Of The President, Rollins College Dec 2013

Plc Quarterly For December 2013, Office Of The President, Rollins College

PLC Quarterly

No abstract provided.


Radical Purpose: The Critical Reference Dialogue At A Progressive Urban College, Kate Adler Dec 2013

Radical Purpose: The Critical Reference Dialogue At A Progressive Urban College, Kate Adler

Urban Library Journal

Abstract: Metropolitan College of New York pioneered “Purpose-Centered Education,” a pedagogical model that blends theory and practice in students’ jobs and lives to produce graduates with a guiding vision of social justice. This paper explores critical information literacy and the reference dialog in the context of the Purpose-Centered Education.


Reductions In Serum Igf-1 During Aging Impair Health Span, Zhenwei Gong, Oran Kennedy, Hui Sun, Yingjie Wu, Garry A. Williams, Laura Klein, Luis Cardoso, Ronald W. Matheny Jr, Gene B. Hubbard, Yuji Ikeno, Roger P. Farrar, Mitchell B. Schaffler, Martin L. Adamo, Radhika H. Muzumdar, Shoshana Yakar Dec 2013

Reductions In Serum Igf-1 During Aging Impair Health Span, Zhenwei Gong, Oran Kennedy, Hui Sun, Yingjie Wu, Garry A. Williams, Laura Klein, Luis Cardoso, Ronald W. Matheny Jr, Gene B. Hubbard, Yuji Ikeno, Roger P. Farrar, Mitchell B. Schaffler, Martin L. Adamo, Radhika H. Muzumdar, Shoshana Yakar

Publications and Research

In lower or simple species, such as worms and flies, disruption of the insulin-like growth factor (IGF)-1 and the insulin signaling pathways has been shown to increase lifespan. In rodents, however, growth hormone (GH) regulates IGF-1 levels in serum and tissues and can modulate lifespan via/or independent of IGF- 1. Rodent models, where the GH/IGF-1 axis was ablated congenitally, show increased lifespan. However, in contrast to rodents where serum IGF-1 levels are high throughout life, in humans, serum IGF-1 peaks during puberty and declines thereafter during aging. Thus, animal models with congenital disruption of the GH/ IGF-1 axis are unable …