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2013

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Pittsburg State University Annual Commencement, May 2013, Pittsburg State University May 2013

Pittsburg State University Annual Commencement, May 2013, Pittsburg State University

Commencement, 1903-Present

Program of undergraduate and graduate commencement exercises at Pittsburg State University on May of 2013

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Biopiracy And Vaccines: Indonesia And The World Health Organization’S New Pandemic Influenza Plan, Shawn C. Smallman Ph.D. May 2013

Biopiracy And Vaccines: Indonesia And The World Health Organization’S New Pandemic Influenza Plan, Shawn C. Smallman Ph.D.

Journal of International and Global Studies

Viral samples of avian influenza are essential to preparing pre-pandemic vaccines. In 2007, the conflicting interests of the developed and developing nations led Indonesia to briefly stop sharing viral samples. The result was a struggle in which the two blocs argued for different paradigms for viral sample sharing. The first paradigm, articulated by the developed world, depicted the issue as one of health security, in which international law mandated the sharing of viral samples. The second paradigm, advanced by the developing world, depicted viral sample sharing as a form of biopiracy, which violated countries’ sovereign control of their biological resources. …

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Not Quite Out On The Streets: Examining Protective And Risk Factors For Housing Insecurity Among Low-Income Urban Fathers, Colleen E. Wynn May 2013

Not Quite Out On The Streets: Examining Protective And Risk Factors For Housing Insecurity Among Low-Income Urban Fathers, Colleen E. Wynn

Masters Theses & Specialist Projects

It has long been acknowledged that housing is essential for access to employment, social services, healthcare, and other forms of assistance that help move people out of poverty. Through identifying dimensions of housing insecurity, policymakers, as well as researchers, will have a better understanding of the protective factors that make families more secure and the risk factors that raise their level of insecurity. These analyses use resident and non-resident, low-income, urban fathers’ responses to the five publicly available waves of the Fragile Families and Child Wellbeing (n = 4378) dataset to examine the relationship between protective and risk factors and …

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Effect Of Leaving Ligands Of Platinum(Ii) Diamine Complexes On Dna And Protein Residues, Ramya Kolli May 2013

Effect Of Leaving Ligands Of Platinum(Ii) Diamine Complexes On Dna And Protein Residues, Ramya Kolli

Masters Theses & Specialist Projects

Platinum compounds are widely used drugs in cancer treatments. Although DNA is the biological target, reaction of platinum compounds with proteins is also potentially significant. Our objective is to study the effects of leaving ligands on the relative reactivity between 5'-GMP (guanosine 5' phosphate), a key DNA target, and N-Acetyl - L-Methionine (N-AcMet), a key protein target. We have used NMR spectroscopy to monitor reactions with N-AcMet and 5'-GMP added to a platinum complex to see which products are formed preferentially. Previous research showed that both a non-bulky complex such as [Pt(en)(D2O)2]2+ [en=ethylenediamine], and a …

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Communication Among Emerging Adult Siblings, Jessica Leigh Paulsen May 2013

Communication Among Emerging Adult Siblings, Jessica Leigh Paulsen

Masters Theses & Specialist Projects

The study sought to explore the emerging adult sibling dyad through qualitative
inquiry. By doing so, the collected data bring new meaning to why and how emerging adult siblings communicate. Also, by including both siblings, this study sought to highlight a different perspective of sibling communication. Extant research on the emerging adulthood stage of life is limited. The current study explored the sibling dyad during this phase of life, and three themes emerged: siblings become friends, changes during emerging adulthood, conflict negotiation, and taking a parental role.

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Forensic Investigation Of Stamped Markings Using A Large-Chamber Scanning Electron Microscope And Computer Analysis For Depth Determination, Eric Douglas Jones May 2013

Forensic Investigation Of Stamped Markings Using A Large-Chamber Scanning Electron Microscope And Computer Analysis For Depth Determination, Eric Douglas Jones

Masters Theses & Specialist Projects

All firearms within the United States are required by the Gun Control Act to be physically marked with a serial number; which is at least 0.003” in depth and 1/16” in height. The purpose of a serial number is to make each firearm uniquely identifiable and traceable. Intentional removal of a serial number is a criminal offense and is used to hide the identity and movements of the involved criminal parties. The current standard for firearm serial number restoration is by chemical etching; which is time & labor intensive as well as destructive to the physical evidence (firearm). It is …

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The Effects Of Fire On The Vernal Herbs Of An Eastern Mesic Forest, David Randolph Kem May 2013

The Effects Of Fire On The Vernal Herbs Of An Eastern Mesic Forest, David Randolph Kem

Masters Theses & Specialist Projects

The effects of fire on vernal herbs of the mesic forests of eastern North America are poorly understood. I studied the influence of prescribed fire on species richness, abundance of rare and common species, and density of exotics in the vernal herbaceous layer. To determine these effects, three sites in central Kentucky were surveyed prior to and following one of three treatments: spring burn, winter burn, or negative control. I conducted low-intensity spring burns in April 2010 and winter burns in February 2011. I used chi square analyses to test for changes in species richness, abundance of rare species, abundance …

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The Influence Of Children's Affective Ties On The Goal Clarification Step Of Social Information Processing, Amanda C. Thorn May 2013

The Influence Of Children's Affective Ties On The Goal Clarification Step Of Social Information Processing, Amanda C. Thorn

Masters Theses & Specialist Projects

Previous studies have shown that children’s social goals are influenced by
emotion and that emotions can be manipulated using relationships. The present study combines these previous findings by examining the effect of children’s relationships on social goals. Social goals were examined in second and fifth grade children using hypothetical ambiguous provocation situations in which the relationship between the participant and the provocateur was manipulated by inserting the name of a friend, enemy, or a neutral peer into the story. After each situation, children rated the importance of four different social goals, indicating which of the four would be the most …

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Food Defense Among Meat Processing And Food Service Establishments In Kentucky, Morgan Webb-Yeates May 2013

Food Defense Among Meat Processing And Food Service Establishments In Kentucky, Morgan Webb-Yeates

Masters Theses & Specialist Projects

Agroterrorism is the deliberate introduction of a plant or animal disease with the
goal of causing fear, economic instability, illness, or death. After the 2002 terrorist
attacks on the World Trade Center, the security of the food supply is of increasing
concern to the United States. A major incidence of agroterrorism or food tampering would have far reaching impacts on the economy and public health. The first objective of this project was to determine knowledge and concern of agroterrorism in meat processing facilities in Kentucky, and to determine knowledge and concern of food tampering and food defense in food service …

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Effects Of Cisplatin Analog Size On The Reaction With Dna Bases, Swathi Nandala May 2013

Effects Of Cisplatin Analog Size On The Reaction With Dna Bases, Swathi Nandala

Masters Theses & Specialist Projects

Cancer is the second leading cause of death in the United States. Cisplatin is one of the well-known anti-cancer agents used to treat testicular and ovarian cancers. It mainly binds to the DNA bases, which leads to cell death. The cytotoxic activity of the cisplatin analogs is due to the interaction of platinum with nucleotides like adenine at N7 or N1 position and guanine at N7 position. Guanine is the primary target for cisplatin analogs whereas adenine is the secondary target. Cisplatin analogs, [Pt(Me5dien)(D2O)]2+[Me5dien = N,N,N’,N’,N’’-pentamethyl diethylene triamine] and …

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The Early Dissemination Defect Attributed To Disruption Of Decorin-Binding Proteins Is Abolished In Chronic Murine Lyme Borreliosis, Denise M. Imai, D. Scott Samuels, Sunlian Feng, Emir Hodzic, Kim Olsen, Stephen W. Barthold May 2013

The Early Dissemination Defect Attributed To Disruption Of Decorin-Binding Proteins Is Abolished In Chronic Murine Lyme Borreliosis, Denise M. Imai, D. Scott Samuels, Sunlian Feng, Emir Hodzic, Kim Olsen, Stephen W. Barthold

Biological Sciences Faculty Publications

The laboratory mouse model of Lyme disease has revealed that Borrelia burgdorferi differentially expresses numerous outer surface proteins that influence different stages of infection (tick-borne transmission, tissue colonization, dissemination, persistence, and tick acquisition). Deletion of two such outer surface proteins, decorin-binding proteins A and B (DbpA/B), has been documented to decrease infectivity, impede early dissemination, and, possibly, prevent persistence. In this study, DbpA/B-deficient spirochetes were confirmed to exhibit an early dissemination defect in immunocompetent, but not immunodeficient, mice, and the defect was found to resolve with chronicity. Development of disease (arthritis and carditis) was attenuated only in the early stage …

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On Ideals In Romantic Relationships, Paul Hjellming, Lori Bergstrom, Bo Johnson, Erica Osmondson May 2013

On Ideals In Romantic Relationships, Paul Hjellming, Lori Bergstrom, Bo Johnson, Erica Osmondson

Communication Studies Student Works

Being in relationships is inseparable from being human. Humans are communicators and naturally form connections with other humans around them. Relationships help individuals assess who they are and who they would like to be. Individuals use relationships to satisfy emotional, physical, and instrumental needs. Some of these needs are best met by romantic relationships between two individuals. Romantic relationships, which many people often expect to partake in throughout their lives, are intimately affected by standards, assumptions, and ideals. Though some deny it, everyone has standards for the person with whom they could potentially be romantically involved. This study will focus …

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The Genre Of The Meme, Thomas Monson May 2013

The Genre Of The Meme, Thomas Monson

Communication Studies Student Works

The development and proliferation of the Internet has led to numerous discoveries in the study of media and communication. Such a recent development in online communication is the rise of the online meme. The traditional meaning of meme has been transformed and has developed a new meaning within the sphere of online communication. The meme as defined by its new meaning has recurred in myriads, which have provided enough reason and data to develop a rhetorical genre for the subject. The first half of this study—the background—will begin with an orientation to the meme, an explanation of generic criticism, and …

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Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At Α1 Subunit-Containing Gabaa Receptor Subtypes In Midazolam- But Not Cocaine-Experienced Rhesus Monkeys., Nina M Shinday, Eileen K Sawyer, Bradford D Fischer, Donna M Platt, Stephanie C Licata, John R Atack, Gerard R Dawson, David S Reynolds, James K Rowlett May 2013

Reinforcing Effects Of Compounds Lacking Intrinsic Efficacy At Α1 Subunit-Containing Gabaa Receptor Subtypes In Midazolam- But Not Cocaine-Experienced Rhesus Monkeys., Nina M Shinday, Eileen K Sawyer, Bradford D Fischer, Donna M Platt, Stephanie C Licata, John R Atack, Gerard R Dawson, David S Reynolds, James K Rowlett

Cooper Medical School of Rowan University Departmental Research

Benzodiazepines are prescribed widely but their utility is limited by unwanted side effects, including abuse potential. The mechanisms underlying the abuse-related effects of benzodiazepines are not well understood, although α1 subunit-containing GABAA receptors have been proposed to have a critical role. Here, we examine the reinforcing effects of several compounds that vary with respect to intrinsic efficacy at α2, α3, and α5 subunit-containing GABAA receptors but lack efficacy at α1 subunit-containing GABAA receptors ('α1-sparing compounds'): MRK-623 (functional selectivity for α2/α3 subunit-containing receptors), TPA023B (functional selectivity for α2/α3/α5 subunit-containing receptors), and TP003 (functional selectivity for α3 subunit-containing receptors). The reinforcing effects …

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Medicalization Of Mental Disorders: 1970- To The Present, W. Joseph Wyatt May 2013

Medicalization Of Mental Disorders: 1970- To The Present, W. Joseph Wyatt

Psychology Faculty Research

A thirty-five year escalation of emphasis on biological causation has rendered, for many, medications as the treatment of choice for mental disorders. Non-drug treatment may be cast aside, as a result.

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Molecular Mechanisms Underlying Rb Protein Function, Frederick A. Dick, Seth M. Rubin May 2013

Molecular Mechanisms Underlying Rb Protein Function, Frederick A. Dick, Seth M. Rubin

Paediatrics Publications

Inactivation of the RB protein is one of the most fundamental events in cancer. Coming to a molecular understanding of its function in normal cells and how it impedes cancer development has been challenging. Historically, the ability of RB to regulate the cell cycle placed it in a central role in proliferative control, and research focused on RB regulation of the E2F family of transcription factors. Remarkably, several recent studies have found additional tumour-suppressor functions of RB, including alternative roles in the cell cycle, maintenance of genome stability and apoptosis. These advances and new structural studies are combining to define …

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University Magazine Spring 2013, University News Service, Office Of Alumni Relations May 2013

University Magazine Spring 2013, University News Service, Office Of Alumni Relations

University Publications

This is the official magazine for RIT Alumni. Issued thrice a year in spring, fall and winter. Printing began in 1999.

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Regulation Of Succinate-Fuelled Mitochondrial Respiration In Liver And Skeletal Muscle Of Hibernating Thirteen-Lined Ground Squirrels., Jason C L Brown, Dillon J Chung, Alex N Cooper, James F Staples May 2013

Regulation Of Succinate-Fuelled Mitochondrial Respiration In Liver And Skeletal Muscle Of Hibernating Thirteen-Lined Ground Squirrels., Jason C L Brown, Dillon J Chung, Alex N Cooper, James F Staples

Biology Publications

Hibernating ground squirrels (Ictidomys tridecemlineatus) alternate between two distinct metabolic states throughout winter: torpor, during which metabolic rate (MR) and body temperature (Tb) are considerably suppressed, and interbout euthermia (IBE), during which MR and Tb briefly return to euthermic levels. Previous studies showed suppression of succinate-fuelled respiration during torpor in liver and skeletal muscle mitochondria; however, these studies used only a single, saturating succinate concentration. Therefore, they could not address whether mitochondrial metabolic suppression occurs under physiological substrate concentrations or whether differences in the kinetics of mitochondrial responses to changing substrate concentration might also contribute to mitochondrial metabolic regulation during …

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Analysis Of Time-Dependent Integrodifference Population Models, Taylor J. Mcadam May 2013

Analysis Of Time-Dependent Integrodifference Population Models, Taylor J. Mcadam

HMC Senior Theses

The population dynamics of species with separate growth and dispersal stages can be described by a discrete-time, continuous-space integrodifference equation relating the population density at one time step to an integral expression involving the density at the previous time step. Prior research on this model has assumed that the equation governing the population dynamics remains fixed over time, however real environments are constantly in flux. We show that for time-varying models, there is a value Λ that can be computed to determine a sufficient condition for population survival. We also develop a framework for analyzing persistence of a population for …

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Mathematical Knowledge For Teaching And Visualizing Differential Geometry, Nathan Pinsky May 2013

Mathematical Knowledge For Teaching And Visualizing Differential Geometry, Nathan Pinsky

HMC Senior Theses

In recent decades, education researchers have recognized the need for teachers to have a nuanced content knowledge in addition to pedagogical knowledge, but very little research was conducted into what this knowledge would entail. Beginning in 2008, math education researchers began to develop a theoretical framework for the mathematical knowledge needed for teaching, but their work focused primarily on elementary schools. I will present an analysis of the mathematical knowledge needed for teaching about the regular curves and surfaces, two important concepts in differential geometry which generalize to the advanced notion of a manifold, both in a college classroom and …

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A Comparison And Catalog Of Intrinsic Tumor Growth Models, Elizabeth A. Sarapata May 2013

A Comparison And Catalog Of Intrinsic Tumor Growth Models, Elizabeth A. Sarapata

HMC Senior Theses

Determining the dynamics and parameter values that drive tumor growth is of great interest to mathematical modelers, experimentalists and practitioners alike. We provide a basis on which to estimate the growth dynamics of ten different tumors by fitting growth parameters to at least five sets of published experimental data per type of tumor. These timescale tumor growth data are also used to determine which of the most common tumor growth models (exponential, power law, logistic, Gompertz, or von Bertalanffy) provides the best fit for each type of tumor. In order to compute the best-fit parameters, we implemented a hybrid local-global …

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Cost-Benefit Analysis Of Farmer Training In Ghanaian Cocoa Farming, Michael Norton May 2013

Cost-Benefit Analysis Of Farmer Training In Ghanaian Cocoa Farming, Michael Norton

Agricultural Economics and Agribusiness Undergraduate Honors Theses

While billions of dollars flow into low-income countries each year to help alleviate poverty, assessing the effectiveness of these dollars is a challenging task. The literature is rich in studies that measure the benefits of rural development programs. However, many of these studies lack a temporal dimension because they measure cost and benefits for only capital investments and for only a single, static year, while not accounting for skill enhancement. By only measuring net producer benefits during the life of the development program, the cost-benefit analyses (CBA) may not truly capture the full net benefits of a given program. In …

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Transition To Psychosis In Cannabis Abusers, Amresh Srivastava May 2013

Transition To Psychosis In Cannabis Abusers, Amresh Srivastava

Data and Test Instruments

Transition to psychosis in Cannabis abusersSchizophrenia is a debilitating disease of major public health importance, the incidence of which shows prominent worldwide variation (up to fivefold) and is about 40% greater in men than in women. Furthermore, epidemiological studies have shown that the incidence is higher among those who grow up in urban areas and among migrants. Recent evidence indicates that, although the neurochemical origins of schizophrenia do not necessarily lie in dopamine dysregulation, this operates as the final common pathway underlying positive psychotic symptoms and may also play a role in negative and cognitive symptoms. The last few years …

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Ua45/6 Commencement Program, Wku Registrar May 2013

Ua45/6 Commencement Program, Wku Registrar

WKU Administration Documents

Commencement program listing graduates.

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The Effects Of Intestinal Microbial Community Structure On Disease Manifestation In Il-10-/- Mice Infected With Helicobacter Hepaticus, Courtney Robinson May 2013

The Effects Of Intestinal Microbial Community Structure On Disease Manifestation In Il-10-/- Mice Infected With Helicobacter Hepaticus, Courtney Robinson

Department of Biology Faculty Publications

BackgroundThe aberrant inflammation that is the hallmark of the inflammatory bowel diseases (IBD) is associated with several factors, including changes in the intestinal microbiota. Here, we confirmed that an intestinal microbiota is needed for development of typhlocolitis in Helicobacter hepaticus infected IL-10-/- C57BL/6 mice, and investigated the role of the microbiota in modulating disease.ResultsWe altered the murine microbiota by treatment with the antibiotics vancomycin or cefoperazone prior to H. hepaticus infection. Through surveys of the 16S rRNA encoding-gene, analyses of histology and changes in expression of host mediators, we correlated alterations in the microbiota with host responses. We found that …

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Interpersonal (Re)Relating: Investigating The Experience Of Refriending, Paul Edgerton Stafford May 2013

Interpersonal (Re)Relating: Investigating The Experience Of Refriending, Paul Edgerton Stafford

Dissertations

This study reveals findings from qualitative research investigating the relational experience of friends reconnecting after a long period of disconnect. Borrowed from the lexicon of social networking terminology, this particular process is conceptualized here as a process of refriending: when two individuals whose interactive behavior and shared lived experiences that once characterized their friendship have reestablished contact and are interacting after an extended period of communication dormancy. A content analysis of 15 participant interviews about their refriending experiences resulted in a typology of 12 thematic categories related to identity, disclosure, motivation, and communication competence. Aspects of relational continuity as well …

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Gardens Are A Physical Manifestation Of Culture: Postmodern Public Parks Of The Twenty-First Century Will Be Built On The Infrastructure Of The Industrial Age, Steven W. Grant May 2013

Gardens Are A Physical Manifestation Of Culture: Postmodern Public Parks Of The Twenty-First Century Will Be Built On The Infrastructure Of The Industrial Age, Steven W. Grant

Master of Liberal Studies Theses

Gardens are not simply arranged trees, lawns, walkways, fountains and ponds. They are a physical expression of the values and beliefs of culture. Adapting industrial age infrastructure into public parks is a reflection of culture in the postmodern age as much as the cloister garden expressed theology in the middle-ages, the sensuous garden expressed the humanism of the Renaissance, the Baroque garden expressed autocratic power, the neo-classical garden expressed reason, and the picturesque garden expressed awe of nature. The postmodern postindustrial public park of today is being built on the infrastructure of the industrial age; it is an expression of …

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Science’S Harmful Power, Rochelle Thomas May 2013

Science’S Harmful Power, Rochelle Thomas

Master of Liberal Studies Theses

The focus of this thesis is to address and acknowledge issues identifying how applied science’s progressive impact can harm people in any society. The advancement of scientific technology can cause detrimental results to the general public. A few examples are dropping of the atomic bomb; prescription medications dispensed to patients before adequate testing studies have been completed; and scientific fraud. The scientific community promotes the scientist based on their research without thoroughly testing the theory or discovery. The scientist will go to extreme lengths to achieve specific results can cause damaging effects on society. Scientists can falsely influence society and …

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Reborn In Adversity - Memoir Excerpt And Review Of Resiliency Research: Risks And Traits, Alina Patterson May 2013

Reborn In Adversity - Memoir Excerpt And Review Of Resiliency Research: Risks And Traits, Alina Patterson

Master of Liberal Studies Theses

Reborn in Adversity describes the journey one young girl makes as she seeks to self-actualize amidst multiple risk factors or packages. Raised in an abusive, hypocritical, and assaultive family, the author is faced with crisis after crises along each milestone of life. Once she leaves her abusive family, the risks and crises multiply in magnitude and number. In this journey she exhibits multiple resiliency traits that allow at risk children to rebound from adversity. She does more than rebound, as she is convinced that she has become a “better person” than she would have been had she not been tested …

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Effect Of Ph And Temperature On The Binding Interactions Of Caffeine And Chlorogenic Acid With Sodium Caseinate, Emily S. Kong May 2013

Effect Of Ph And Temperature On The Binding Interactions Of Caffeine And Chlorogenic Acid With Sodium Caseinate, Emily S. Kong

Master's Theses

Coffee is a popular and well-loved beverage consumed worldwide by millions of people every day. While most patrons of coffee do so because of its unique and satisfying taste, consumers may be unaware of the potential beneficial health effects it also imparts. The antioxidants found in green coffee beans collectively known as chlorogenic acids (CGA) and caffeine are two of the most abundant bioactive compounds present in coffee. Both these bioactive compounds have been implicated in many studies to impart a wide range of health benefits, from reducing the risk of Type 2 diabetes, to their use as aides in …

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