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Review Of "Translational Stem Cell Research: Issues Beyond The Debate On The Moral Status Of The Human Embryo" Edited By K. Hug And G. Hermerén, John B. Jenkins

Biology Faculty Works

No abstract provided.

Contents, Anon

Washington Journal of Environmental Law & Policy

No abstract provided.

Gota A Gota, No. 2, 2013, Toni Pérez Fernández

KIP Articles

Portada de GOTA A GOTA nº 2 (2013) -- Editorial y datos de publicación -- Sima de Tinguatón (La Sima del Diablo) / Diego Serantes Vergara y Cristina Peña Muiño -- Nematodos monónquidos (Nematoda, Mononchida) de la Cueva del Jabalí (Jaén, España) / Joaquín Abolafia Cobaleda y Juana Isabel Martín Martínez -- Exploraciones inéditas en la provincia de Jaén. "Los primeros espeleólogos realmente fueron franceses" / Antonio Pérez Ruiz -- Anomalías morfológicas en Onychiurus gevorum, el Onychiurus de los miembros del G.E.V., nuevo nombre para Onychiurus gevi Arbea, 2012 (Collembola, Onychiuridae) / Javier I. Arbea -- Exploraciones en el Nacimiento …

A Simple Assay To Screen Antimicrobial Compounds Potentiating The Activity Of Current Antibiotics, Junaid Iqbal, Ruqaiyyah Siddiqui, Shahana Urooj Kazmi, Naveed Ahmed Khan

Department of Biological & Biomedical Sciences

Antibiotic resistance continues to pose a significant problem in the management of bacterial infections, despite advances in antimicrobial chemotherapy and supportive care. Here, we suggest a simple, inexpensive, and easy-to-perform assay to screen antimicrobial compounds from natural products or synthetic chemical libraries for their potential to work in tandem with the available antibiotics against multiple drug-resistant bacteria. The aqueous extract of Juglans regia tree bark was tested against representative multiple drug-resistant bacteria in the aforementioned assay to determine whether it potentiates the activity of selected antibiotics. The aqueous extract of J. regia bark was added to Mueller-Hinton agar, followed by …

Association Of Body Iron Status With The Risk Of Premature Acute Myocardial Infarction In A Pakistani Population, Mohammadl Perwaiz Iqbal, Naseema Mehbooi Ali, Asal Khan Tareen, Mohsin Yakub, Saleeml Perwaizl Iqbal, Khalida Iqbal, Ghulam Haider

Department of Biological & Biomedical Sciences

Background

Coronary artery disease is very common in Pakistani population. Some of the studies carried out on Western populations have shown a relationship between body iron status as determined by the ratio of concentrations of serum soluble transferrin receptor (sTfR) to ferritin and the risk of acute myocardial infarction (AMI). In order to investigate whether increased body iron status has any relationship with the risk of premature AMI in Pakistani population, a case-control study was carried out.

Methodology/Principal findings

In this case-control study, 203 consecutive AMI patients [146 males and 57 females; age range 18–45 years] admitted to the National …

The Conduit, Volume 13, No. 1, June 2013, Annette Summers Engel

The KWI Conduit

Contents: Welcome to The Conduit -- KWI Happenings -- Nicole Ridlen: 2013 Wilson Scholarship Recipient -- Upcoming 2014 Conference – Hypogene Cave Morphologies -- Research Focus: Long-term Instrumentation for Omega Cave -- The 13th Sinkhole Conference Did Not Sink Expectations! -- Carbon and Boundaries in Karst Meeting -- Upcoming Conferences

Brovine: Mammary Gland Gene Database, Therin C. Irwin

Computer Science and Software Engineering

Brovine is used by the Animal Science department at Cal Poly to catalog and analyze genetic information. Brovine, or the Mammary Gland Gene Database, is a system used to store and categorize genetic information which is gathered through experimentation and through TESS, a web application that lets users search through catalogs of similar genetic information. This document describes the purpose, use, and maintenance of Brovine.

Gene Patents In Australia: A Game Theory Approach, Kate M. Mead

Washington International Law Journal

Gene patent validity is one of the most controversial issues in patent law. In Australia, the question of whether to eliminate human gene patents has reached both Parliament and the federal courts. Opponents of gene patents argue that gene patents increase the cost of healthcare and impede progress in genetic research. Proponents respond that gene patents are essential incentives for the biotech industry, and that Australia has an obligation to recognize them under the WTO-administered Treaty on Trade-Related Aspects of Intellectual Property Rights (“TRIPS”). Because patents require inventors to publically disclose their discoveries, Australia’s rejection of the gene patent system …

The New Wave Of Florida Energy: The Regulatory Path To Harnessing Marine Hydrokinetic Power, Andrew Thornquest

Public Land & Resources Law Review

No abstract provided.

Raised Eyebrow Test Produces Further Head-Scratching: Punitive Damages In Ondrisek V. Hoffman, The, Valerie Shands

Missouri Law Review

Ondrisek reveals that although the Eighth Circuit uses the same test as the Supreme Court, it certainly applies it differently. When comparing Ondrisek and other Eighth Circuit cases, one sees a subtle pattern that diverges from the Supreme Court’s jurisprudence. However, these differences are not yet distinct enough for the Supreme Court to have granted certiorari to resolve the inconsistencies.

Potential Oversummering And Overwintering Regions For The Wheat Stripe Rust Pathogen In The Contiguous United States, Dipak Sharma-Poudyal, Xianming Chen, Richard Alan Rupp

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Epidemics of wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), are more frequent in the regions where Pst can oversummer and overwinter. Regions for potential oversummering and overwintering of Pst were determined in the contiguous United States using a survival index (SI) ranging from 0 (most unfavorable) to 10 (most favorable) developed based on long-term weather data. The pathogen can survive in cool summer in the most regions north of latitude 40°N, particularly Washington, Idaho, Montana, Oregon and California. Due to limiting high temperatures, it survives marginally during summer in Arkansas, Delaware, Georgia, Iowa, Illinois, …

Distorted And Diminished Tort Claims For Women, Jamie Abrams

Scholarly Articles in Law Reviews & Journals

Childbirth is distinctly characterized in tort law by the literal emergence of a potential putative plaintiff. This Article seeks to position the birthing woman — distinct from the pregnant woman or the parent — squarely within the negligence framework and, in doing so, to challenge prevailing assumptions dominating obstetric medical decision-making. The existence of two patients and two putative plaintiffs is unique to childbirth, yet largely unexamined in tort. This Article examines how the dominant focus on fetal harms in modern childbirth overshadows the birthing woman in tort and distorts the normative dualities of childbirth.

While theoretically childbirth falls within …

''Get Your Asphalt Off My Ancestors!'': Reclaiming Richmond's African Burial Ground, Mai-Linh Hong

Faculty Journal Articles

By treating spatial conflict as one way communities wrestle with the memory and legacy of slavery, this article unites critical landscape analysis, a tool of legal geography, with legal and cultural analysis and recent scholarship on African American reparations. A slave cemetery lay beneath a parking lot in Shockoe Bottom, a neighborhood of downtown Richmond that was once a major slave-trading hub. In recent years, controversy arose over the site’s use, generating racially charged local debate and two failed lawsuits seeking to preserve the site. This article examines the significance of the African Burial Ground controversy by analyzing its symbolic, …

Spread Spectrum Jamming - Part 2, Casey Burke, Christian Hume, Javier Meza

Electrical Engineering

Direct-sequence spread spectrum (DSSS) is a special modulation technique used in many telecommunication devices which uses a wide bandwidth relative to single-frequency carrier modulation techniques. Like the name suggests, the spectral content of wireless signals are spread across a range of frequencies to increase the security of transmitted signals by reducing the potential impact of outside interference (i.e. noise, jamming). This resistance against outside interference and jamming has particular application in the field of electronic warfare where spread spectrum jamming techniques may prove to be an effective way of shutting down remotely controlled enemy vehicles.

Last year, a group of …

Antipsychotic Prescribing Pathways, Polypharmacy, And Clozapine Use In Treatment Of Schizophrenia, Jessica L. Gören, Meterko, Sandra Williams, Gary J. Young, Errol Baker, Chia-Hung Chou, Amy M. Kilbourne, Mark S. Bauer

Pharmacy Practice and Clinical Research Faculty Publications

Objective

To ensure optimal care for patients with schizophrenia, antipsychotic medications must be appropriately prescribed and used. Therefore, the primary objectives of this study were to identify and describe pathways for antipsychotic prescribing, assess the consistency of observed pathways with treatment guidelines, and describe variability across facilities.

Methods

Data from Veterans Affairs administrative data sets from fiscal year (FY) 2003 to FY 2007 were gathered for analysis in this retrospective cohort study of antipsychotic prescribing pathways among 13 facilities across two regional networks. Patients with a new episode of care for schizophrenia or schizoaffective disorder in FY 2005 were identified, …

Exploring Volatile General Anesthetic Binding To A Closed Membrane-Bound Bacterial Voltage-Gated Sodium Channel Via Computation., S G Raju, Annika F Barber, David N Lebard, Michael L Klein, Vincenzo Carnevale

Department of Neuroscience Faculty Papers

Despite the clinical ubiquity of anesthesia, the molecular basis of anesthetic action is poorly understood. Amongst the many molecular targets proposed to contribute to anesthetic effects, the voltage gated sodium channels (VGSCs) should also be considered relevant, as they have been shown to be sensitive to all general anesthetics tested thus far. However, binding sites for VGSCs have not been identified. Moreover, the mechanism of inhibition is still largely unknown. The recently reported atomic structures of several members of the bacterial VGSC family offer the opportunity to shed light on the mechanism of action of anesthetics on these important ion …

Acetylation Of The Cell-Fate Factor Dachshund Determines P53 Binding And Signaling Modules In Breast Cancer., Ke Chen, Kongming Wu, Michael Gormley, Adam Ertel, Jing Wang, Wei Zhang, Jie Zhou, Gabriele Disante, Zhiping Li, Hallgeir Rui, Andrew A Quong, Steven B Mcmahon, Haiteng Deng, Michael P Lisanti, Chenguang Wang, Richard G Pestell

Department of Cancer Biology Faculty Papers

Breast cancer is a leading form of cancer in the world. The Drosophila Dac gene was cloned as an inhibitor of the hyperactive epidermal growth factor (EGFR), ellipse. Herein, endogenous DACH1 co-localized with p53 in a nuclear, extranucleolar compartment and bound to p53 in human breast cancer cell lines, p53 and DACH1 bound common genes in Chip-Seq. Full inhibition of breast cancer contact-independent growth by DACH1 required p53. The p53 breast cancer mutants R248Q and R273H, evaded DACH1 binding. DACH1 phosphorylation at serine residue (S439) inhibited p53 binding and phosphorylation at p53 amino-terminal sites (S15, S20) enhanced DACH1 binding. DACH1 …

The Deadliest School Shooting In American History: A Dramatistic Analysis Of The Virginia Tech Massacre, Natalie Susanne Zafis

Communication Studies

No abstract provided.

The Virtual Bulletin Board: A Feminist Critique Of Pinterest, Alexandra B. Davila

Communication Studies

No abstract provided.

General Catalog 2013-2014 (Summer, Fall 2013), Utah State University

University Catalogs

This catalog contains information on the Academic Departments and Programs as well as Course Descriptions for the above school year at Utah State University. To avoid large file downloads, the Academic Departments and Programs information is located in this file. The Course Description information is located in the secondary file.

Sexual Dimorphisms In Habitat-Specific Morphology And Behavior In The Green Anole Lizard, A K. Dill, T J. Sanger, Andrew C. Battles, Michele A. Johnson

Biology Faculty Research

Species that occur in variable environments often exhibit morphological and behavioral traits that are specific to local habitats. Because the ability to move effectively is closely associated with structural habitat, locomotor traits may be particularly sensitive to fine-scale habitat differences. Anolis lizards provide an excellent opportunity to study the relationship between locomotion and natural perch use in the field, as laboratory studies have demonstrated that lizards that use broader perches develop longer limbs and have higher sprint speeds. We examined Anolis carolinensis (the green anole) in three habitats in close proximity. Our goals were to determine whether habitat-specific differences in …

Use Of Image Cytometry For Quantification Of Pathogenic Fungi In Association With Host Cells, Charlotte A. Berkes, Leo Li-Ying Chan, Alisha Wilkinson, Benjamin Paradis

Biology Faculty Publications

Studies of the cellular pathogenesis mechanisms of pathogenic yeasts such as Candida albicans, Histoplasma capsulatum, and Cryptococcus neoformans commonly employ infection of mammalian hosts or host cells (i.e. macrophages) followed by yeast quantification using colony forming unit analysis or flow cytometry. While colony forming unit enumeration has been the most commonly used method in the field, this technique has disadvantages and limitations, including slow growth of some fungal species on solid media and low and/or variable plating efficiencies, which is of particular concern when comparing growth of wild-type and mutant strains. Flow cytometry can provide rapid quantitative information regarding yeast …

Diversity Of Plant Methionine Sulfoxide Reductases B And Evolution Of A Form Specific For Free Methionine Sulfoxide, Dung Tien Le, Lionel Tarrago, Yasuko Watanabe, Alaattin Kaya, Byung Cheon Lee, Uyen Tran, Rie Nishiyama, Dmitri E. Fomenko, Vadim N. Gladyshev, Lam-Son Phan Tran

Department of Biochemistry: Faculty Publications

Methionine can be reversibly oxidized to methionine sulfoxide (MetO) under physiological conditions. Organisms evolved two distinct methionine sulfoxide reductase families (MSRA & MSRB) to repair oxidized methionine residues. We found that 5 MSRB genes exist in the soybean genome, including GmMSRB1 and two segmentally duplicated gene pairs (GmMSRB2 and GmMSRB5, GmMSRB3 and GmMSRB4). GmMSRB2 and GmMSRB4 proteins showed MSRB activity toward protein-based MetO with either DTT or thioredoxin (TRX) as reductants, whereas GmMSRB1 was active only with DTT. GmMSRB2 had a typical MSRB mechanism with Cys121 and Cys 68 as catalytic and resolving residues, respectively. Surprisingly, this enzyme also possessed …

Near-Infrared Optical Imaging For Monitoring The Regeneration Of Osteogenic Tissue-Engineered Constructs., Elizabeth A. Cowles, Joy L. Kovar, Evan T. Curtis, Huihui Xu, Shadi F. Othman

All Faculty Articles - School of Engineering and Computer Science

Millions of cases of bone injury or loss due to trauma, osteoporosis, and cancer occur in the United States each year. Because bone is limited in its ability to regenerate, alternative therapy approaches are needed. Bone tissue engineering has the potential to correct musculoskeletal disorders through the development of cell-based substitutes for osteogenic tissue replacement. Multiple medical imaging techniques such as magnetic resonance microscopy (MRM) were investigated recently; these techniques are able to provide useful information on the anatomical and structural changes of developing bone. However, there is a need for noninvasive approaches to evaluate biochemical constituents and consequent compositional …

The Junco Called Cassiar, Rick Wright

Nebraska Bird Review

A well-marked male Cassiar Junco is subtly distinctive. In its overall grayness, the bird closely recalls a Slate-colored Junco, but the darkness of the head, breast, and nape approaches that of a male Oregon Junco, creating a more striking contrast between the "hood" and the rest of the upperparts than is visible in any but the very blackest of male Slate-coloreds. More significant than the colors themselves is their distribution: the blackish nape is sharply set off from the grayer or brownish back, and the dark of the breast meets the paler gray of the flank and the white of …

Contributions Of Stocked And Naturally Reproduced Rainbow Trout In The Deerfield Reservoir System, Jacob L. Davis, Jerry W. Wilhite, Greg Simpson, Michael E. Barnes, Kaite N. Bertrand, David W. Willis

The Prairie Naturalist

Deerfield Reservoir in the Black Hills of South Dakota and its tributary system are managed as hatchery supplemented rainbow trout (Oncorhynchus mykiss) fisheries. Three genetically unique strains of rainbow trout (Shasta, Erwin and McConaughy) are stocked into the system. Recently, juvenile rainbow trout of unknown origin were collected in the tributary system above Deerfield Reservoir, indicating potential natural reproduction. Understanding the genetic origins and ability of these rainbow trout to contribute to the fishery is essential in determining the proper management strategy for these waters. Our objectives were to 1) evaluate the genetic origins of potentially naturally reproduced rainbow trout …

Generalized Simulated Annealing For Global Optimization: The Gensa Package, Yang Xiang, Sylvain Gubian, Brain Suomela, Julia Hoeng

The R Journal

Many problems in statistics, finance, biology, pharmacology, physics, mathematics, economics, and chemistry involve determination of the global minimum of multidimensional functions. R packages for different stochastic methods such as genetic algorithms and differential evolution have been developed and successfully used in the R community. Based on Tsallis statistics, the R package GenSA was developed for generalized simulated annealing to process complicated non-linear objective functions with a large number of local minima. In this paper we provide a brief introduction to the R package and demonstrate its utility by solving a non-convex portfolio optimization problem in finance and the Thomson problem …

News From The Bioconductor Project, Bioconductor Team

The R Journal

Bioconductor 2.12 was released on 3 October 2012. It is compatible with R 3.0.1, and consists of 671 software packages and more than 675 up-to-date annotation packages. The release includes 65 new software packages, and enhancements to many others. Descriptions of new packages and updated NEWS files provided by current package maintainers are at http://bioconductor.org/news/bioc_2_12_release/.

Possible Directions For Improving Dependency Versioning In R, Jeroen Ooms

The R Journal

One of the most powerful features of R is its infrastructure for contributed code. The built-in package manager and complementary repositories provide a great system for development and exchange of code, and have played an important role in the growth of the platform towards the de-facto standard in statistical computing that it is today. However, the number of packages on CRAN and other repositories has increased beyond what might have been foreseen, and is revealing some limitations of the current design. One such problem is the general lack of dependency versioning in the infrastructure. This paper explores this problem in …

Beadarrayfilter: An R Package To Filter Beads, Anyiawung Chiara Forcheh, Geert Verbeke, Adetayo Kasim, Dan Lin, Ziv Shkedy, Willem Talloen, Hinrich W.H. Göhlmann, Lieven Clement

The R Journal

Microarrays enable the expression levels of thousands of genes to be measured simultaneously. However, only a small fraction of these genes are expected to be expressed under different experimental conditions. Nowadays, filtering has been introduced as a step in the microarray pre-processing pipeline. Gene filtering aims at reducing the dimensionality of data by filtering redundant features prior to the actual statistical analysis. Previous filtering methods focus on the Affymetrix platform and can not be easily ported to the Illumina platform. As such, we developed a filtering method for Illumina bead arrays. We developed an R package, beadarrayFilter, to implement …