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2013

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Prey Indices And Behaviors At A Gray Fox Den In San Mateo County, California, L. Mark Elbroch, Maximilian L. Allen Jul 2013

Prey Indices And Behaviors At A Gray Fox Den In San Mateo County, California, L. Mark Elbroch, Maximilian L. Allen

Western North American Naturalist

The gray fox (Urocyon cinereoargenteus) is an under-studied species in North America. Here we provide data gathered through observations over 17 d at a gray fox den in San Mateo County, California. We recorded prey indices through direct observation, as well as through indirect observation with photos recorded by motion-triggered cameras. The largest prey was a mule deer fawn, which we determined was killed by a gray fox. This finding is the first record of gray fox predation on mule deer. Lagomorphs and rodents formed the majority of prey items. We also recorded behavior that both contradicted and …

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Front Matter, Vol. 73 No. 2 Jul 2013

Front Matter, Vol. 73 No. 2

Western North American Naturalist

No abstract provided.

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Synthesis, Testing And Crystallographic Studies Of Allosteric Modifiers Of Hemoglobin, Tanvi Deshpande Jul 2013

Synthesis, Testing And Crystallographic Studies Of Allosteric Modifiers Of Hemoglobin, Tanvi Deshpande

Theses and Dissertations

The major physiological function of hemoglobin (Hb) is to bind, transport and deliver oxygen to tissues; made efficient by endogenous effectors, such as protons and 2,3-diphosphoglycerate. Synthetic allosteric effectors of Hb (AEHs) are also known to modulate Hb oxygen affinity, showing potential for the treatment of sickle cell disease (SCD) and ischemic-related diseases. In this project, AEHs which increase Hb affinity for oxygen, including derivatives of the anti-sickling compounds, 5HMF and benzaldehydes, as well as an AEH that decreases Hb affinity for oxygen, RSR-13, were synthesized for their effects on Hb oxygen binding property and their capability to release NO …

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The Plastid Genome Of Najas Flexilis: Adaptation To Submersed Environments Is Accompanied By The Complete Loss Of The Ndh Complex In An Aquatic Angiosperm, Elena L. Peredo, Ursula M. King, Donald H. Les Jul 2013

The Plastid Genome Of Najas Flexilis: Adaptation To Submersed Environments Is Accompanied By The Complete Loss Of The Ndh Complex In An Aquatic Angiosperm, Elena L. Peredo, Ursula M. King, Donald H. Les

Open Access Author Fund Awardees' Articles

The re-colonization of aquatic habitats by angiosperms has presented a difficult challenge to plants whose long evolutionary history primarily reflects adaptations to terrestrial conditions. Many aquatics must complete vital stages of their life cycle on the water surface by means of floating or emergent leaves and flowers. Only a few species, mainly within the order Alismatales, are able to complete all aspects of their life cycle including pollination, entirely underwater. Water- pollinated Alismatales include seagrasses and water nymphs ( Najas ), the latter being the only freshwater genus in the family Hydrocharitaceae with subsurface water-pollination. We have determined the complete …

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Kniola A Trip To The Bernheim Fire Tower, Ohio University College Of Arts & Sciences Jul 2013

Kniola A Trip To The Bernheim Fire Tower, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Individual Differences In Emotion-Cognition Interactions: Emotional Valence Interacts With Serotonin Transporter Genotype To Influence Brain Systems Involved In Emotional Reactivity And Cognitive Control, Melanie Stollstorff, Yuko Munakata, Arielle P.C. Jensen, Ryan M. Guild, Harry R. Smolker, Joseph M. Devaney, Marie T. Banich Jul 2013

Individual Differences In Emotion-Cognition Interactions: Emotional Valence Interacts With Serotonin Transporter Genotype To Influence Brain Systems Involved In Emotional Reactivity And Cognitive Control, Melanie Stollstorff, Yuko Munakata, Arielle P.C. Jensen, Ryan M. Guild, Harry R. Smolker, Joseph M. Devaney, Marie T. Banich

Genomics and Precision Medicine Faculty Publications

The serotonin transporter gene (5-HTTLPR) influences emotional reactivity and attentional bias toward or away from emotional stimuli, and has been implicated in psychopathological states, such as depression and anxiety disorder. The short allele is associated with increased reactivity and attention toward negatively-valenced emotional information, whereas the long allele is associated with increased reactivity and attention towardpositively-valenced emotional information. The neural basis for individual differences in the ability to exert cognitive control over these bottom-up biases in emotional reactivity and attention is unknown, an issue investigated in the present study. Healthy adult participants were divided into two groups, either homozygous …

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Dietary Selenium Deficiency Exacerbates Dss-Induced Epithelial Injury And Aom/Dss-Induced Tumorigenesis., C. W. Barrett, K. Singh, A. K. Motley, M. K. Lintel, E. Matafonova, A. M. Bradley, W. Ning, Shenika Poindexter Toliver Jul 2013

Dietary Selenium Deficiency Exacerbates Dss-Induced Epithelial Injury And Aom/Dss-Induced Tumorigenesis., C. W. Barrett, K. Singh, A. K. Motley, M. K. Lintel, E. Matafonova, A. M. Bradley, W. Ning, Shenika Poindexter Toliver

Faculty and Staff Publications

Selenium (Se) is an essential micronutrient that exerts its functions via selenoproteins. Little is known about the role of Se in inflammatory bowel disease (IBD). Epidemiological studies have inversely correlated nutritional Se status with IBD severity and colon cancer risk. Moreover, molecular studies have revealed that Se deficiency activates WNT signaling, a pathway essential to intestinal stem cell programs and pivotal to injury recovery processes in IBD that is also activated in inflammatory neoplastic transformation. In order to better understand the role of Se in epithelial injury and tumorigenesis resulting from inflammatory stimuli, we examined colonic phenotypes in Se-deficient or …

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Paediatric Mri Research Ethics: The Priority Issues, Nuala Kenny, Jocelyn Downie, Ryan D'Arcy, Jennifer Marshall, Matthias Schmidt, Michael Hadskis Jul 2013

Paediatric Mri Research Ethics: The Priority Issues, Nuala Kenny, Jocelyn Downie, Ryan D'Arcy, Jennifer Marshall, Matthias Schmidt, Michael Hadskis

Research Papers, Working Papers, Conference Papers

In this paper we first briefly describe neuroimaging technology our reasons for studying magnetic resonance imaging MRI technology and then provide a discussion of what we have identified as priority issues for paediatric MRI research We examine the issues of respectful involvement of children in the consent process as well as privacy and confidentiality for this group of MRI research participants In addition we explore the implications of unexpected findings for paediatric MRI research participants Finally we explore the ethical issues concerning advances in functional MRI This paper aims to provide a clear description of priority paediatric MRI research ethics …

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Circulating Tumor Dna To Monitor Metastatic Breast Cancer., Massimo Cristofanilli, Paolo Fortina Jul 2013

Circulating Tumor Dna To Monitor Metastatic Breast Cancer., Massimo Cristofanilli, Paolo Fortina

Kimmel Cancer Center Faculty Papers

No abstract provided.

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Pharmacological Interventions For Somatoform Disorders In Adults [Protocol], Maria Kleinstäuber, Michael Witthöft, Andrés Steffanowski, Michael Lambert, Günter Meinhardt, Klaus Lieb, Wolfgang Hiller Jul 2013

Pharmacological Interventions For Somatoform Disorders In Adults [Protocol], Maria Kleinstäuber, Michael Witthöft, Andrés Steffanowski, Michael Lambert, Günter Meinhardt, Klaus Lieb, Wolfgang Hiller

Psychology Faculty Publications

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of pharmacological interventions for somatoform disorders (specifically somatisation disorder, undifferentiated somatoform disorder, somatoform autonomic dysfunction, and pain disorder) in adults.

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Horner's Syndrome Secondary To Neuroblastoma, Roberto A. Cruz, T. K. Tran, Nicky R. Holdeman, Christian Cajavilca, Rosa A. Tang Jul 2013

Horner's Syndrome Secondary To Neuroblastoma, Roberto A. Cruz, T. K. Tran, Nicky R. Holdeman, Christian Cajavilca, Rosa A. Tang

School of Medicine Publications

Horner’s syndrome is classically characterized by a triad of miosis, partial ptosis and anhidrosis. The etiology is due to an interruption in the sympathetic innervation to the eye. A prompt diagnosis is crucial, given that Horner’s syndrome could be a manifestation of a life-threatening condition. A thorough case history and clinical evaluation must be employed to arrive at the diagnosis. An important means for confirming Horner’s syndrome is pharmacological testing, which is also used to localize the level where the sympathetic chain is compromised. Following the diagnosis and localization of the lesion, an algorithm should be followed to determine the …

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Characterization Of Freshwater Natural Dissolved Organic Matter (Dom): Mechanistic Explanations For Protective Effects Against Metaltoxicity And Direct Effects On Organisms, Hassan A. Al-Reasi, Chris M. Wood, D. Scott Smith Jul 2013

Characterization Of Freshwater Natural Dissolved Organic Matter (Dom): Mechanistic Explanations For Protective Effects Against Metaltoxicity And Direct Effects On Organisms, Hassan A. Al-Reasi, Chris M. Wood, D. Scott Smith

Chemistry Faculty Publications

Dissolved organic matter (DOM) exerts direct and indirect influences on aquatic organisms. In order to better understand how DOM causes these effects, potentiometric titration was carried out for a wide range of autochthonous and terrigenous freshwater DOM isolates. The isolates were previously characterized by absorbance and fluorescence spectroscopy. Proton binding constants (pKa) were grouped into three classes:acidic (pKa ≤ 5), intermediate (5 < pKa ≤ 8.5) and basic (pKa > 8.5). Generally, the proton site densities (LT) showed maximum peaks at the acidic and basic ends around pKa values of 3.5 and 10, respectively. More …

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An Integrative Framework For Bayesian Variable Selection With Informative Priors For Identifying Genes And Pathways, Bin Peng, Dianwen Zhu, Bradley P. Ander, Xiaoshuai Zhang, Fuzhong Xue, Frank R. Sharp, Xiaowei Yang Jul 2013

An Integrative Framework For Bayesian Variable Selection With Informative Priors For Identifying Genes And Pathways, Bin Peng, Dianwen Zhu, Bradley P. Ander, Xiaoshuai Zhang, Fuzhong Xue, Frank R. Sharp, Xiaowei Yang

Publications and Research

The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of subjects. Traditional gene-wise selection methods using univariate analyses face difficulty to incorporate correlational, structural, or functional structures amongst the molecular measures. For microarray gene expression data, we first summarize solutions in dealing with ‘large p, small n’ problems, and then propose an integrative Bayesian variable selection (iBVS) framework for simultaneously identifying causal …

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Prospectus, July 3, 2013, Ted Sutterlund, Matthew Jackson, Mace Mackiewicz, Alex Wallner Jul 2013

Prospectus, July 3, 2013, Ted Sutterlund, Matthew Jackson, Mace Mackiewicz, Alex Wallner

Prospectus 2013

"SUPERIOR DONUTS" BRINGS LAUGHS AND TEARS; Study habits hindered by everyday distractions; The next phase in the drone wars; Presenting yourself to employers: How to build a professional online image; Snowden's punishment should be calculated carefully; Who gets admitted to college?; "The Last of Us" a once in a generation game; Parkland Golf wins national championship; New consoles showcased at E3 2013

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An Inverted Repeat In The Ospc Operator Is Required For Induction In Borrelia Burgdorferi, Dan Drecktrah, Laura S. Hall, Laura L. Hoon-Hanks, D. Scott Samuels Jul 2013

An Inverted Repeat In The Ospc Operator Is Required For Induction In Borrelia Burgdorferi, Dan Drecktrah, Laura S. Hall, Laura L. Hoon-Hanks, D. Scott Samuels

Biological Sciences Faculty Publications

Borrelia burgdorferi, the spirochete that causes Lyme disease, differentially regulates synthesis of the outer membrane lipoprotein OspC to infect its host. OspC is required to establish infection but then repressed in the mammal to avoid clearance by the adaptive immune response. Inverted repeats (IR) upstream of the promoter have been implicated as an operator to regulate ospC expression. We molecularly dissected the distal inverted repeat (dIR) of the ospC operator by site-directed mutagenesis at its endogenous location on the circular plasmid cp26. We found that disrupting the dIR but maintaining the proximal IR prevented induction of OspC synthesis by …

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Isolation And Molecular Characterization Of Leptospira Interrogans And Leptospira Borgpetersenii Isolates From The Urban Rat Populations Of Kuala Lumpur, Malaysia, D. Benacer, M.Z. Siti Nursheena, A. Fairuz, R.L. Galloway, Kwai Lin Thong Jul 2013

Isolation And Molecular Characterization Of Leptospira Interrogans And Leptospira Borgpetersenii Isolates From The Urban Rat Populations Of Kuala Lumpur, Malaysia, D. Benacer, M.Z. Siti Nursheena, A. Fairuz, R.L. Galloway, Kwai Lin Thong

Research Publications (2011 to 2015)

Rats are considered the principal maintenance hosts of Leptospira. The objectives of this study were isolation and identification of Leptospira serovars circulating among urban rat populations in Kuala Lumpur. Three hundred urban rats (73% Rattus rattus and 27% R. norvegicus) from three different sites were trapped. Twenty cultures were positive for Leptospira using dark-field microscopy. R. rattus was the dominant carrier (70%). Polymerase chain reaction (PCR) confirmed that all isolates were pathogenic Leptospira species. Two Leptospira serogroups, Javanica and Bataviae, were identified using microscopic agglutination test (MAT). Pulsed-field gel electrophoresis (PFGE) identified two serovars in the urban rat populations: L. …

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The Role Of Nuclear Bmp2 In The Cell Cycle And Tumorigenesis, Brandt Alan Nichols Jul 2013

The Role Of Nuclear Bmp2 In The Cell Cycle And Tumorigenesis, Brandt Alan Nichols

Theses and Dissertations

Bone morphogenetic protein 2 (BMP2) is a secreted growth factor that is essential for proper embryonic development and proliferation. Our laboratory discovered a nuclear variant of BMP2 (nBMP2) which is produced when translation is initiated at an alternative start codon within the BMP2 gene. When translation occurs at the downstream start codon, the resulting protein lacks the ER signal peptide, thereby allowing cytoplasmic translation and nuclear localization. Our aim is to distinguish the role of this nuclear localized variant from secreted BMP2. Overexpression of nBMP2 in HEK293 and HT29 cell lines resulted in a higher percentage of cells in proliferative …

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New Tool To Help Define Role Of Mystery Appendage, Greg Williams Jul 2013

New Tool To Help Define Role Of Mystery Appendage, Greg Williams

Browse All News

No abstract provided.

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Film Features Mcclintock's Prose, Voice Of Harrison Ford, Reporter Staff Jul 2013

Film Features Mcclintock's Prose, Voice Of Harrison Ford, Reporter Staff

Browse All News

No abstract provided.

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Variation In Salamander Tail Regeneration Is Associated With Genetic Factors That Determine Tail Morphology, Gareth J. Voss, D. Kevin Kump, John A. Walker, S. Randal Voss Jul 2013

Variation In Salamander Tail Regeneration Is Associated With Genetic Factors That Determine Tail Morphology, Gareth J. Voss, D. Kevin Kump, John A. Walker, S. Randal Voss

Biology Faculty Publications

Very little is known about the factors that cause variation in regenerative potential within and between species. Here, we used a genetic approach to identify heritable genetic factors that explain variation in tail regenerative outgrowth. A hybrid ambystomatid salamander (Ambystoma mexicanum x A. andersoni) was crossed to an A. mexicanum and 217 offspring were induced to undergo metamorphosis and attain terrestrial adult morphology using thyroid hormone. Following metamorphosis, each salamander’s tail tip was amputated and allowed to regenerate, and then amputated a second time and allowed to regenerate. Also, DNA was isolated from all individuals and genotypes were …

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Volume 50, Number 46: July 03, 2013, University Of North Dakota Jul 2013

Volume 50, Number 46: July 03, 2013, University Of North Dakota

University Letter Archive

No abstract provided.

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Rapid Biodiversity Assessment Grid Sampling (Citizen Science) In The White Mountains, Northern Alaska, Usa, June 2013, Falk Huettmann Jul 2013

Rapid Biodiversity Assessment Grid Sampling (Citizen Science) In The White Mountains, Northern Alaska, Usa, June 2013, Falk Huettmann

Faculty

This data set consists of a Rapid Biodiversity Sampling from a non-intrusive citizen science GRID (5*5 geo-referenced sampling + 5 random plots = 30 plots overall). It includes raw count data for 305 bird observations of 14 identified bird species, and plants from the 25+5 survey sampling plots (3m radius), as well as insects from four trapping webs (3m radius, 25 traps each, 3 repeats; mostly spiders were detected). The survey was done between 25th of June and 27th of June in 2013 at the White Mountains (north to the NorthForkBirch and Twelvemile Creeks - near the Steese Hgw 6) …

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The Bg News July 03, 2013, Bowling Green State University Jul 2013

The Bg News July 03, 2013, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. July 03, 2013. Volume 92-Issue 104.

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Subtle Paranodal Injury Slows Impulse Conduction In A Mathematical Model Of Myelinated Axons., Charles F. Babbs, Riyi Shi Jul 2013

Subtle Paranodal Injury Slows Impulse Conduction In A Mathematical Model Of Myelinated Axons., Charles F. Babbs, Riyi Shi

Weldon School of Biomedical Engineering Faculty Publications

This study explores in detail the functional consequences of subtle retraction and detachment of myelin around the nodes of Ranvier following mild-to-moderate crush or stretch mediated injury. An equivalent electrical circuit model for a series of equally spaced nodes of Ranvier was created incorporating extracellular and axonal resistances, paranodal resistances, nodal capacitances, time varying sodium and potassium currents, and realistic resting and threshold membrane potentials in a myelinated axon segment of 21 successive nodes. Differential equations describing membrane potentials at each nodal region were solved numerically. Subtle injury was simulated by increasing the width of exposed nodal membrane in nodes …

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Development And Validation Of The Abstinence Motivation Scale, Natalie Johnson Jul 2013

Development And Validation Of The Abstinence Motivation Scale, Natalie Johnson

Theses and Dissertations

The purpose of this study was to design the Abstinence Motivation Scale-Sex (AMS-Sex), a scale to assess adolescent motivations for sexual abstinence using the self-determination theory (SDT) motivation continuum as a framework. Previous sexual abstinence research, SDT measurement studies, pilot study data, and expert panel feedback were used to develop the initial 77-item AMS-Sex. The sample consisted of 695 adolescents (aged 15 to 18; M age = 16.49, SD = 1.08; 50.8% male) recruited online from the across the U.S. Participants completed an online survey. The sample was randomly split into two samples. Independent samples t-tests indicated that sample 1 …

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The Role Of Smpb In Licensing Tmrna Entry Into Stalled Ribosomes, Mickey R. Miller Jul 2013

The Role Of Smpb In Licensing Tmrna Entry Into Stalled Ribosomes, Mickey R. Miller

Theses and Dissertations

Ribosomes translate the genetic information contained in mRNAs into protein by linking together amino acids with the help of aminoacyl-tRNAs. In bacteria, protein synthesis stalls when the ribosome reaches the 3'-end of truncated mRNA transcripts lacking a stop codon. Trans-translation is a conserved bacterial quality control process that rescues stalled ribosomes. Transfer-messenger RNA (tmRNA) and its protein partner SmpB mimic a tRNA by entering the A site of the ribosome and accepting the growing peptide chain. The ribosome releases the truncated mRNA and resumes translation on the tmRNA template. The open reading frame found on tmRNA encodes a peptide tag …

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Comparison Of Systemic And Mucosal Immunization Withhelper-Dependent Adenoviruses For Vaccination Against Mucosal Challenge With Shiv, Eric A. Weaver, Pramod N. Nehete, Bharti P. Nehete, Guojun Yang, Stephanie J. Buchl, Patrick W. Hanley, Donna Palmer, David C. Montefiori, Guido Ferrari, Philip Ng, K. Jagannadha Sastry, Michael A. Barry Jul 2013

Comparison Of Systemic And Mucosal Immunization Withhelper-Dependent Adenoviruses For Vaccination Against Mucosal Challenge With Shiv, Eric A. Weaver, Pramod N. Nehete, Bharti P. Nehete, Guojun Yang, Stephanie J. Buchl, Patrick W. Hanley, Donna Palmer, David C. Montefiori, Guido Ferrari, Philip Ng, K. Jagannadha Sastry, Michael A. Barry

School of Biological Sciences: Faculty Publications

Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To test this, rhesus macaques were vaccinated by intramuscular (i.m.) or intravaginal (ivag.) routes with helperdependent adenoviral (HD-Ad) vectors expressing HIV-1 envelope. Macaques were first immunized intranasally with species C Ad serotype 5 (Ad5) prior to serotype-switching with species C HD-Ad6, Ad1, Ad5, and Ad2 vectors expressing env followed by rectal challenge with CCR5-tropic SHIV-SF162P3. Vaccination by the systemic route generated stronger systemic CD8 T …

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The Birds Of Nebraska, Revised Edition 2013, Paul A. Johnsgard Jul 2013

The Birds Of Nebraska, Revised Edition 2013, Paul A. Johnsgard

Zea E-Books Collection

This summary of the birds of Nebraska has been restricted to those species that have been convincingly reported at least once in Nebraska from historic time to the present. It has also been modified in its current revision to conform very closely in that regard to the most recent Nebraska Ornithologists’ Union’s “Official List of the Birds of Nebraska” (Brogie, 2010; NOU Records Committee, 2011 and annual updates). The N.O.U.’s official state list of birds (455 species as of 2013, including 329 “regular” species, 42 of “casual” occurrence, 68 accidentals, and six extinct or extirpated species) is based on actual …

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S3-S4 Linker Modulation Of Voltage Sensor Relaxation In Voltage Gated Potassium Channels, W. Everett Fox Jul 2013

S3-S4 Linker Modulation Of Voltage Sensor Relaxation In Voltage Gated Potassium Channels, W. Everett Fox

Theses and Dissertations

It is commonly assumed that the voltage dependence for activation of voltage-gated channels is an intrinsic characteristic of the protein that remains unchanged during electrical activity. However, sporadic reports have suggested otherwise by showing that voltage dependence changes in a use-dependent manner resulting in a voltage dependence shift towards negative potentials (Bezanilla et al., 1982; Bruening-Wright and Larsson, 2007; Kuzmenkin et al., 2004; Labro et al., 2012; Larsson and Elinder, 2000; Olcese et al., 1997; Piper et al., 2003; Shirokov et al., 1992). Although the mechanism underlying the shift in voltage dependence remains unclear, this process seems to have two …

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Attentional Guiding Through Embodied And Image Cues In An Intelligent Tutoring System, Whitney Layne Cade Jul 2013

Attentional Guiding Through Embodied And Image Cues In An Intelligent Tutoring System, Whitney Layne Cade

Electronic Theses and Dissertations Archive

While the impact of pedagogical agent pointing and dynamic visual aids in intelligent tutoring systems has been evaluated by many researchers, there remains a question as to how the combination of the two can impact a student's learning and agent perceptions. In this study, 34 university students were exposed to four Biology lectures delivered by a lifelike agent. The impact of two attentional guiding techniques (agent pointing and sequential image display) on students' opinions of the agent, learning, and gaze behavior were investigated. Agent pointing had no effect on perception of the agent or learning. Sequential display was found to …

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