Digital Commons Network^™

Dysfunctional Gene Regulation Of The Meiotic Program In An Interspecific Yeast Hybrid, Devjanee Swain Lenz

Arts & Sciences Graduate Student Theses and Dissertations

Speciation, the evolutionary process by which species arise, is a fundamental biological concept. One of the major goals of evolutionary genetics is to understand the genetic basis of reproductive isolation (RI), a collection of barriers that prevents two species from forming viable or fertile hybrids. Given the lack of viable or fertile hybrid progeny, identifying genes that impact RI as well as their functions has been difficult. Thus we lack a view of the total genetic contribution to RI. Recently the budding yeast Saccharomyces has served as an evolutionary model, as abundant sequence, expression, and phenotypic data exist for the …

Faculty Guidebook, August 2013, Lindenwood University

Employee Handbooks

Information and guidelines for Lindenwood University faculty.

Multicultural Students Enrich Their Summer, Hannah Dhue

News and Events (Discontinued Series)

No abstract provided.

Connect 202 - August 2013

Connect

Click on the DOWNLOAD button to obtain a PDF of this issue.

Source Assessment Of Deposited Particles In A Slovenian Show Cave (Postojnska Jama): Evidence Of Long-Lasting Anthropogenic Impact, Gregor Muri, Aleksandra Jovičić, Andrej Mihevc

International Journal of Speleology

Postojnska jama (Postojna Cave) is one of the most famous karst caves in the world and has been a well-known tourist attraction for nearly 200 years. It is particularly famous for its unique double-track railway. Eight heavy metals – aluminium (Al), chromium (Cr), copper (Cu), iron (Fe), lead (Pb), manganese (Mn), strontium (Sr), and zinc (Zn) – were determined in dust deposits by ICP-MS in order to assess sources of deposited particles on the cave walls. The samples were collected along the main passage in the cave, at different horizontal and vertical levels, in order to test horizontal homogeneity and …

Forty Years Of Epikarst: What Biology Have We Learned?, Tanja Pipan, David Culver

International Journal of Speleology

Epikarst is not only an important component of the hydrogeology of karst and an active site of speleogenesis, it is habitat for a number of species adapted to subterranean life. Water in epikarst, with a residence time of days to months, is a highly heterogeneous habitat, and the animals are primarily sampled from continuously sampling dripping water or collecting from residual drip pools. While the subterranean fauna of cracks and crevices has been known for over 100 years, it is only in the past several decades that epikarst has been recognized as a distinct habitat, with reproducing populations of stygobionts. …

Spatial And Temporal Changes In Invertebrate Assemblage Structure From The Entrance To Deep-Cave Zone Of A Temperate Marble Cave, Benjamin W. Tobin, Benjamin T. Hutchins, Benjamin F. Schwartz

International Journal of Speleology

Seasonality in surface weather results in seasonal temperature and humidity changes in caves. Ecological and physiological differences among trogloxenes, troglophiles, and troglobionts result in species-dependent responses to this variability. To investigate these responses, we conducted five biological inventories in a marble cave in the Sierra Nevada Range, California, USA between May and December, 2010. The cave was divided into six quadrats and temperature was continuously logged in each (humidity was logged at the entrance and in the deep cave). With increasing distance from the entrance, temperature changes were increasingly attenuated and lagged relative to surface temperature. Linear regressions were created …

Student Success Strategies In The Stem Fields As A Diversity Practice, Thomas Kling

Leading for Change

No abstract provided.

Errata, Human Biology Editors

Human Biology

"Commentary on Chen et al.'s 'Worldwide Analysis of Genetic and Linguistic Relationships of Human Populations' (1995)," by Paul Heaggerty, Human Biology 84(5):573-580 (October 2012).

Paul Heggarty is the correct spelling for the author of "Commentary on Chen et al.'s 'Worldwide Analysis of Genetic and Linguistic Relationships of Human Populations' (1995)," which was published in the October 2012 issue of Human Biology. With deepest apologies to the author and readers, the spelling of Dr. Heggarty's name has been corrected in all digital versions of the article.

2013 Fall Convocation Program, Office Of Communications & Marketing, Morehead State University.

Communications and Marketing Publications Archive

Fall convocation program held on August 14, 2017.

Immunopathology Of Cd4+ T Cell-Mediated Autoimmune Responses To Central Nervous System Antigens: Role Of Il-16, Harley Y. Tse, Dusanka S. Skundric, William W. Cruikshank, Paul C. Montgomery, Robert P. Lisak

Neurology Faculty Publications

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating and degenerative disease of the central nervous system (CNS). While etiology of the disease remains unknown, genetic susceptibility and autoimmune mechanisms in the initiation and progression of the disease have been strongly suggested. Experimental autoimmune encephalomyelitis (EAE) is commonly used to study immune regulation of MS. Infiltration by CD4⁺ T cells, through blood-brain barrier (BBB), precedes the onset and relapses of MS. CNS migration and homing patterns of T cells are tightly synchronized by astrocyte and microglia derived cytokines and chemokines. Autoimmune, CNS antigenreactive, infiltrating T cells produce and locally release …

We Are...Marshall, August 14, 2013, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Brian Steele V. Aramark Corp

2013 Decisions

USDC for the District of New Jersey

Volume 50, Number 52: August 14, 2013, University Of North Dakota

University Letter Archive

No abstract provided.

Proceedings Of The 2013 Berry Summer Thesis Institute, University Of Dayton. University Honors Program

Proceedings of the Berry Summer Thesis Institute (2013-Present)

Thanks to a gift from the Berry Family Foundation and the Berry family, the University Honors Program launched the Berry Summer Thesis Institute in 2012. The institute introduces students in the University Honors Program to intensive research, scholarship opportunities and professional development. Each student pursues a 12-week summer thesis research project under the guidance of a UD faculty mentor. This contains the product of the students' research.

Frontiers, Opportunities, And Challenges In Biochemical And Chemical Catalysis Of Co2 Fixation, Aaron M. Appel, John E. Bercaw, Andrew B. Bocarsly, Holger Dobbek, Daniel L. Dubois, Michel Dupuis, James G. Ferry, Etsuko Fujita, Russ Hille, Paul J.A. Kenis, Cheryl A. Kerfeld, Robert H. Morris, Charles H.F. Peden, Archie R. Portis, Stephen W. Ragsdale, Thomas B. Rauchfuss, Joost N.H. Reek, Lance C. Seefeldt, Rudolf K. Thauer, Grover L. Waldrop

Faculty Publications

The article discusses opportunities and challenges in biochemical and chemical catalysis of carbon dioxide fixation. All biological systems must extract energy from their environments to carry out the metabolic processes associated with life itself. Living organisms have evolved to exist in an amazing variety of environments, and they can use and interconvert energy from a variety of sources. The enzymes required to carry out these important metabolic pathways have evolved over billions of years, and they use readily abundant materials from the environment to achieve these important energy conversion processes. All of these metabolic pathways involve the storage and utilization …

Effect Of Architecture And Porosity On Mechanical Properties Of Borate Glass Scaffolds Made By Selective Laser Sintering, Krishna C. R. Kolan, Ming-Chuan Leu, Greg Hilmas, Taylor Comte

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The porosity and architecture of bone scaffolds, intended for use in bone repair or replacement, are two of the most important parameters in the field of bone tissue engineering. The two parameters not only affect the mechanical properties of the scaffolds but also aid in determining the amount of bone regeneration after implantation. Scaffolds with five different architectures and four porosity levels were fabricated using borate bioactive glass (13-93B3) using the selective laser sintering (SLS) process. The pore size of the scaffolds varied from 400 to 1300 μm. The compressive strength of the scaffolds varied from 1.7 to 15.5 MPa …

Synthesis And Characterization Of Electrodeposited Nanocrystalline Ferromagnetic Cobalt-Iron-Platinum Alloy Films / Teh Seoh Hian, Seoh Hian Teh

Student Works (2010-2019)

In this present work, cobalt-iron, cobalt-platinum, iron-platinum and cobalt-iron-platinum systems were synthesized and characterized. Pure Co film was electrodeposited on brass substrates from sulfate plating baths containing sodium saccharin. The compositions of the electrodeposits were found depended on the concentration of Fe in the electrolytic bath. By alloying Co and Fe, binary Co-Fe alloy film was deposited successfully with various composition of Fe in the electrodeposits. Sodium saccharin was added into plating bath as a grain refining agent to improve the quality of the deposits. The crystallite sizes were calculated from the broadening of X-ray diffraction peak and the sizes …

Bridge To Biology Program Premieres At Morris, University Relations

Campus News Archive

A new program for incoming biology students premieres at Morris this summer.

Biofuel From Microalgae – A Review On The Current Status And Future Trends, Rajee Olaganathan, May Zaw Htet, Lim Yan Ling, Sek Hui Yun

Publications

The constant reliance on fossil fuel energy resources is unsustainable, due to both depleting world reserves and increasing green house gas emissions associated with their use and thus there are dynamic research at the global level envisioned at developing alternative renewable and potentially carbon neutral solid, liquid and gaseous biofuels as alternative energy resources. The contemporary knowledge and technology predictions have proved that among the third generation biofuels especially those derived from microalgae are considered the best reasonable alternative energy resource compared to undeniable drawbacks of first and second generation biofuels. Moreover, its efficiency to sequester carbon from the atmosphere …

Power Of Shame: The Moderating Effects Of Parental And Peer Connection On The Relationship Between Adolescent Shame And Depression, Self-Esteem, And Hope, Alexander L. Hsieh

Theses and Dissertations

Past research and views on shame have indicated that shame has detrimental effects for adolescent development. Little research has focused on the pathways in which shame may affect adolescent traits. Even less studies examine what variables may moderate the effects of shame. Using adolescent self-report questionnaires, this study examined the relationship between adolescent shame and depression, self-esteem, and hope. In addition, this study examined the moderating effect maternal, paternal, and best friend relationships have between shame and adolescent outcome variables. A structural equation moderation model analysis was fit to data from 307 two-parent families. The average age of adolescents for …

Structure Of Octahedral Polyomavirus, Robert Swenson, Dr. David Belnap

Journal of Undergraduate Research

Polyomaviruses (PVs) are viruses that can cause tumors in mammals and fatal diseases in birds. Knowles et al. (2) estimated that over 90% of the human population is infected with a polyomavirus, but these infections are usually dormant, and only show symptoms in patients with compromised immune systems. PVs normally form a capsid with icosahedral symmetry whose structure is known (Figure 1). In this structure, the major capsid protein (VP1) forms a stable pentamer with the C-terminal arms of the proteins extending outwards. VP1 pentamers (filled pentagons, Figure 1) interact with five other pentamers on some vertices, and with six …

A Probabilistic Pair-Hidden Markov Model For Snp Detection In Next Generation Sequencing Data, Nathan Clement, Dr. Quinn Snell

Journal of Undergraduate Research

In order to create and maintain a healthy human body, over three billion nucleotides (molecules of DNA, collectively called a genome) need to work together in harmony. Each cell in the human body needs its own copy of the genome, so during growth an individual’s DNA is replicated many times. Because the process of replication is not perfect, there are occasional mistakes. Sometimes, these mistakes can be fixed by the body’s own repair mechanisms, but occasionally, a single change in one of the three billion molecules in a human genome have lifethreatening results (for example, see the entry on Cystic …

A Weak Structural Approach To Decentralized Control, David Ward, Dr. Sean Warnick

Journal of Undergraduate Research

The research discussed here explores the interplay between dynamical structure functions, the communication structure of a controller and the zero pattern of a controller. Precisely understanding this interplay is a necessary result to utilize dynamical structure functions to help broaden the known tractable class of decentralized control problems. The long term goal of this research is to broaden the set of tractable convex decentralized control problems by utilizing the structure encapsulated in dynamical structure functions. The research highlighted here was presented during the 2010 BYU Spring research conference and published in detail as my undergraduate honors thesis “Decentralized Control Problems: …

Identification Of Important Pathways In Cancerogenesis, Michelle Withers, Dr. W. Evan Johnson

Journal of Undergraduate Research

The human body interacts at a cellular level through a series of events known as biological pathways. These pathways consist of communications at the molecular, cellular, and genetic levels to maintain a healthy, functional body. When the pathways are disrupted, new pathways are formed that can lead to disease. Currently, researchers are trying to understand the role of disrupted and normal pathways in cancer cells. It is necessary to understand the cancerous pathway in order to return the cell to its normal, healthy function.

An Adaptive Bayesian Approach To Threat-Detection Modeling, Bradley Ferguson, Dr. C. Shane Reese

Journal of Undergraduate Research

Detection of biological and chemical threats is an important consideration in the modern national defense policy. Much of the testing and evaluation of threat detection technologies is performed without appropriate uncertainty quantification. Under the guidance of Dr. Shane Reese, my ORCA project dealt with developing a more effective and cost-efficient way of testing threat detection technologies. I utilized a Bayesian Gaussian Process model that allows for a more flexible and robust model t. I also developed an adaptive experimental design scheme that provides more information than a typical experimental design by learning the concentration levels that we are more interested …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern Holds Fall Convocation

Development Of Freeze-Form Extrusion Fabrication With Use Of Sacrificial Material, Ming-Chuan Leu, Diego A. Garcia

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The development of Freeze-form Extrusion Fabrication (FEF) process to fabricate three-dimensional (3D) ceramic parts with use of sacrificial material to build support sections during the fabrication process is presented in this paper. FEF is an environmentally friendly, additive manufacturing process that builds 3D parts in a freezing environment layer-by-layer by computer controlled extrusion and deposition of aqueous colloidal pastes based on computer-aided design (CAD) models. Methyl cellulose was identified as the support material, and alumina was used as the main material in this study. After characterizing the dynamics of extruding alumina and methyl cellulose pastes, a general tracking controller was …

Model For (A)Synchronous/Spontaneous Release, Applied To Cck-Positive Interneuron Synapses, S Rodrigues, M Desroches, M Krupa, J Cortes, A Afia

School of Engineering, Computing and Mathematics

Asynchronous and spontaneous neurotransmitter release remain elusive and constitute topics of considerable research both from the experimental and modeling perspective. This study proposes a parsimonious model that accounts for all modes of vesicle exocytosis and Short-Term Synaptic Plasticity (STSP). The modeling novelty is based on principles of slow-fast dynamical systems theory. The model's validity is shown by its good agreement with experimental data obtained from in vitro electrophysiological dual whole-cell recordings between local cholecystokinin (CKK)-positive, Schaffer collateral associated (SCA) interneurons in the CA1 region of rat hippocampus~\cite{AfiaAli2007,AfiaAli2010}. These unitary synapses display asynchronous release, governed by the retrograde release of endocannabinoid …

Census Overview: Basics, Decennial, Acs, And Estimates, David J. Drozd

CPAR Presents: A Data and Research Series for Community Impact

This presentation features: Terminology & Definitions; Census Datafiles; ACS Data are Released Based Upon the Population of the Geographic Unit; Questionnaires & Concepts; How does CPAR typically analyze race/ethnicity?; Geography; FactFinder Address Search Page & Results; Geography vs. Data (A Duel); Relationship between Data/Datafiles and Geography; PUMA geography; The American Community Survey: What is it?; ACS Methodology in Brief; ACS New Subject Areas; Point Estimates, MOE and Confidence Intervals; ACS Sample Size Increase Began in 2011 and Continues!!; 2012 ACS Data to be released later in 2013; Multi-year Aggregate Estimates: Advantages; The 2009 ACS Nebraska “Double Whammy”; Population Estimates Program: …