Digital Commons Network^™

Coastal Bacterioplankton Community Dynamics In Response To A Natural Disturbance, Sara K. Yeo, Megan J. Huggett, Alexander Eiler, Michael Rappe

Research outputs 2013

In order to characterize how disturbances to microbial communities are propagated over temporal and spatial scales in aquatic environments, the dynamics of bacterial assemblages throughout a subtropical coastal embayment were investigated via SSU rRNA gene analyses over an 8-month period, which encompassed a large storm event. During non-perturbed conditions, sampling sites clustered into three groups based on their microbial community composition: an offshore oceanic group, a freshwater group, and a distinct and persistent coastal group. Significant differences in measured environmental parameters or in the bacterial community due to the storm event were found only within the coastal cluster of sampling …

Application Of Glycyrrhiza Glabra Root As A Novel Adsorbent In The Removal Of Toluene Vapors: Equilibrium, Kinetic, And Thermodynamic Study, Fazel Mohammadi-Moghadam, Mohammad Mehdi Amin,, Mehdi Khiadani, Fariborz Momenbeik, Heshmatollah Nourmoradi, Mohammad Sadegh Hatamipour

Research outputs 2013

The aim of this paper is to investigate the removal of toluene from gaseous solution through Glycyrrhiza glabra root (GGR) as a waste material. The batch adsorption experiments were conducted at various conditions including contact time, adsorbate concentration, humidity, and temperature. The adsorption capacity was increased by raising the sorbent humidity up to 50 percent. The adsorption of toluene was also increased over contact time by 12 h when the sorbent was saturated. The pseudo-second-order kinetic model and Freundlich model fitted the adsorption data better than other kinetic and isotherm models, respectively. The Dubinin-Radushkevich (D-R) isotherm also showed that the …

Energy Efficiency Performance Improvements For Ant-Based Routing Algorithm In Wireless Sensor Networks, A. M. Zungeru, Kah Phooi Seng, Li-Minn Ang, W.C. Chia

Research outputs 2013

The main problem for event gathering in wireless sensor networks (WSNs) is the restricted communication range for each node. Due to the restricted communication range and high network density, event forwarding in WSNs is very challenging and requires multihop data forwarding. Currently, the energy-efficient ant based routing (EEABR) algorithm, based on the ant colony optimization (ACO) metaheuristic, is one of the state-of-the-art energy-aware routing protocols. In this paper, we propose three improvements to the EEABR algorithm to further improve its energy efficiency. The improvements to the original EEABR are based on the following: (1) a new scheme to intelligently initialize …

Retinal Vascular Biomarkers For Early Detection And Monitoring Of Alzheimer's Disease, Shawn Frost, Yogi Kanagasingam, Hamid Sohrabi, J Vignarajan, P Bourgeat, Olivier Salvado, Victor Villemagne, Christopher Rowe, S Lance Macaulay, Cassandra Szoeke, Kathryn A. Ellis, David Ames, Colin L. Masters, Stephanie Rainey-Smith, Ralph N. Martins

Research outputs 2013

The earliest detectable change in Alzheimer's disease (AD) is the buildup of amyloid plaque in the brain. Early detection of AD, prior to irreversible neurological damage, is important for the efficacy of current interventions as well as for the development of new treatments. Although PiB-PET imaging and CSF amyloid are the gold standards for early AD diagnosis, there are practical limitations for population screening. AD-related pathology occurs primarily in the brain, but some of the hallmarks of the disease have also been shown to occur in other tissues, including the retina, which is more accessible for imaging. Retinal vascular changes …

Multiplex Biomarkers In Blood, Veer Bala Bala Gupta, Ramani Sundaram, Ralph N. Martins

Research outputs 2013

Advances in the field of blood biomarker discovery will help in identifying Alzheimer's disease in its preclinical stage, allowing treatment to be initiated before irreversible damage occurs. This review discusses some recent past and current approaches being taken by researchers in the field. Individual blood biomarkers have been unsuccessful in defining the disease pathology, progression and thus diagnosis. This directs to the need for discovering a multiplex panel of blood biomarkers as a promising approach with high sensitivity and specificity for early diagnosis. However, it is a great challenge to standardize a worldwide blood biomarker panel due to the innate …

Rationale, Design And Methods For A Community-Based Study Of Clustering And Cumulative Effects Of Chronic Disease Processes And Their Effects On Ageing: The Busselton Healthy Ageing Study, A James, M Hunter, L Straker, J Beilby, R Bucks, T Davis, R H. Eikelboom, D Hillman, J Hui, J Hung, M Knuiman, D A. Mackey, Robert U. Newton, L J. Palmer, A W. Musk, Investigator Group Busselton Healthy Ageing Study

Research outputs 2013

Background: The global trend of increased life expectancy and increased prevalence of chronic and degenerative diseases will impact on health systems. To identify effective intervention and prevention strategies, greater understanding of the risk factors for and cumulative effects of chronic disease processes and their effects on function and quality of life is needed.The Busselton Healthy Ageing Study aims to enhance understanding of ageing by relating the clustering and interactions of common chronic conditions in adults to function. Longitudinal (3-5 yearly) follow-up is planned. Methods/design. Phase I (recruitment) is a cross-sectional community-based prospective cohort study involving up to 4,000 'Baby Boomers' …

Immune Response To Snake Envenoming And Treatment With Antivenom; Complement Activation, Cytokine Production And Mast Cell Degranulation, Shelley Stone, Geoffrey K. Isbister, Seyed Shahmy, Fahim Mohamed, Chandana Abeysinghe, Harendra Karunathilake, Ariaranee Ariaratnam, Tamara E. Jacoby-Alner, Claire L. Cotterell, Simon G A Brown

Research outputs 2013

Background:Snake bite is one of the most neglected public health issues in poor rural communities worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently causes serious adverse reactions, including hypersensitivity reactions (including anaphylaxis) and pyrogenic reactions. We aimed to investigate the immune responses to Sri Lankan snake envenoming (predominantly by Russell's viper) and antivenom treatment.Methodology/Principal Findings:Plasma concentrations of Interleukin (IL)-6, IL-10, tumor necrosis factor α (TNFα), soluble TNF receptor I (sTNFRI), anaphylatoxins (C3a, C4a, C5a; markers of complement activation), mast cell tryptase (MCT), and histamine were measured in 120 Sri Lankan snakebite victims, both before and …

Markers Of Circulating Tumour Cells In The Peripheral Blood Of Patients With Melanoma Correlate With Disease Recurrence And Progression, Anna L. Reid, M Millward, Robert Pearce, M Lee, M Frank, A Ireland, L Monshizadeh, Tapan Rai, P Heenan, Sandra Medic, P Kumarasinghe, Melanie R. Ziman

Research outputs 2013

Background: Multimarker quantitative real-time polymerase chain reaction (qRT-PCR) represents an effective method for detecting circulating tumour cells in the peripheral blood of patients with melanoma.

Objectives: To investigate whether the phenotype of circulating melanoma cells represents a useful indicator of disease stage, recurrence and treatment efficacy.

Methods: Peripheral blood was collected from 230 patients with melanoma and 152 healthy controls over a period of 3 years and 9 months. Clinical data and blood samples were collected from patients with primary melanoma (early stages, 0-II, n = 154) and metastatic melanoma (late stages, III-IV, n = 76). Each specimen was examined …

A Blood-Based Predictor For Neocortical Aβ Burden In Alzheimer's Disease: Results From The Aibl Study, Samantha Burnham, Noel Faux, William Wilson, Simon Laws, David Ames, Justin Bedo, Ashley Bush, James Doecke, Kathryn Ellis, Richard Head, Gareth Jones, Harri Kiiveri, Ralph N. Martins, Alan Rembach, Christopher Rowe, Olivier Salvado, S Lance Macaulay, Colin Masters, Victor Villemagne

Research outputs 2013

Dementia is a global epidemic with Alzheimer’s disease (AD) being the leading cause. Early identification of patients at risk of developing AD is now becoming an international priority. Neocortical Aβ (extracellular β-amyloid) burden (NAB), as assessed by positron emission tomography (PET), represents one such marker for early identification. These scans are expensive and are not widely available, thus, there is a need for cheaper and more widely accessible alternatives. Addressing this need, a blood biomarker-based signature having efficacy for the prediction of NAB and which can be easily adapted for population screening is described. Blood data (176 analytes measured in …

Occupational Respiratory Health Surveillance At Minara Resources, Murrin Murrin Mine Site [Journal Article], Martyn Cross, Jacques Oosthuizen

Research outputs 2013

A respiratory health study of fly-in-fly-out workers potentially exposed to airborne contaminants, and a control group, was conducted at the Murrin Murrin mine site in Western Australia. Lung function was measured in terms of validated protocols (American Thoracic Society, 1995; Miller et al, 2005). The effect of length of service, as well as work area/department on lung function was established. Repeat lung function tests were conducted after approximately two years, in order to measure decrements over time. Furthermore, testing was conducted on a cohort of refinery workers prior to commencement and upon completion of their work period on-site (swing), in …

How Mean Is The Mean?, Craig P. Speelman, Marek Mcgann

Research outputs 2013

In this paper we voice concerns about the uncritical manner in which the mean is often used as a summary statistic in psychological research. We identify a number of implicit assumptions underlying the use of the mean and argue that the fragility of these assumptions should be more carefully considered. We examine some of the ways in which the potential violation of these assumptions can lead us into significant theoretical and methodological error. Illustrations of alternative models of research already extant within Psychology are used to explore methods of research less mean-dependent and suggest that a critical assessment of the …

Toward A Phen(Omen)Ology Of The Seasons: The Emergence Of The Indigenous Weather Knowledge Project (Iwkp), John Charles Ryan

Research outputs 2013

Since European settlement, the Western calendar has insufficiently accounted for the seasonal nuances and multiple temporalities of Australia. Beginning with Tim Entwistle’s recent proposal to revise the four-season Australian norm, this article traces the emergence of the Western calendar in Europe and its institutionalization ‘Down Under.’ With its emphasis on land-based calendars, the Indigenous Weather Knowledge Project (IWKP) is a partnership between Aboriginal communities and the Bureau of Meteorology aimed at preserving and promoting knowledge of the endemic seasons of Australian regions. As the most recent addition to the IWKP, the six-season Nyoongar calendar of the South-West of Western Australia …

Protected Species: Perspectives On Organisational Life, Maryam Omari, Megan Paull, Julie A. Crews

Research outputs 2013

Analogies can be drawn between a modern organisation and a complex ecosystem. In both, the players compete for scarce resources; survival often depends on how effectively an individual, organism or group capitalises on what is available to them. In natural settings, the laws of nature provide a backdrop to relationships, including where each individual or group is positioned in the hierarchy. In such settings, unusual and complex interrelationships can be formed where groups either assist or manipulate each other to survive. In organisational settings, the laws and boundaries are less clear, context specific and subject to organisational cultures and norms, …

Multi-Component Adsorption Of Benzene, Toluene, Ethylbenzene, And Xylene From Aqueous Solutions By Montmorillonite Modified With Tetradecyl Trimethyl Ammonium Bromide, Heshmatola Nourmoradi, Mehdi Khiadani, Mahnaz Nikaeen

Research outputs 2013

Multicomponent adsorption of benzene, toluene, ethylbenzene, and xylene (BTEX) was assessed in aqueous solutions by montmorillonite modified with tetradecyl trimethyl ammonium bromide (TTAB-Mt). Batch experiments were conducted to determine the influences of parameters including loading rates of surfactant, contact time, pH, adsorbate concentration, and temperature on the adsorption efficiency. Scanning electron microscope (SEM) and X-ray diffractometer (XRD) were used to determine the adsorbent properties. Results showed that the modification of the adsorbent via the surfactant causes structural changes of the adsorbent. It was found that the optimum adsorption condition achieves with the surfactant loading rate of 200 of the cation …

Indirect Measures Of Learning Transfer Between Real And Virtual Environments, Michael J. Garrett, Mark T. Mcmahon

Research outputs 2013

This paper reports on research undertaken to determine the effectiveness of a 3D simulation environment used to train mining personnel in emergency evacuation procedures, designated the Fires in Underground Mines Evacuation Simulator (FUMES). Owing to the operational constraints of the mining facility, methods for measuring learning transfer were employed which did not require real world performance evaluation. Transfer measures that examined simulator performance relative to real world experience, fidelity assessment, and appraisal of the training value of the platform were utilised. Triangulation of results across all three measures indicated the presence of learning transfer, suggesting the viability of indirect measures …

Review Of Kidney Disease Among Indigenous People, Sasha A. Stumpers, Neil J. Thomson

Research outputs 2013

Kidney disease is a significant health problem for all Australians, but severe kidney disease is more common among Indigenous people than among non- Indigenous people. In particular, the prevalence of chronic kidney disease (CKD) and the overall levels of end-stage kidney disease (ESKD) among Aboriginal and Torres Strait Islander peoples are consistently reported as significantly higher than among other Australians. Information on CKD among Indigenous Australians is available from self-reported survey data, as well as from community-based studies and screening programs [10-20] but the main focus in the literature has been on ESKD. The incidence of ESKD is especially high …

Optical Magnetometer Employing Adaptive Noise Cancellation For Unshielded Magnetocardiography, Valentina Tiporlini, Kamal Alameh

Research outputs 2013

This paper demonstrates the concept of an optical magnetometer for magnetocardiography. The magnetometer employs a standard Least-Mean-Squares (LMS) algorithm for heart magnetic field measurement within unshielded environment. Experimental results show that the algorithm can extract a weak heart signal from a much-stronger magnetic noise and detect the P, QRS, and T heart features and completely suppress the common power line noise component at 50 Hz.

A Sense Of Home: A Cultural Geography Of The Leschenault Estuary District: Report, Sandra Wooltorton

Research outputs 2013

Executive Summary

In 2012, a project was implemented to determine the place-based social values of the people of the Leschenault Estuary district. The project included a historical study, a literature review, a survey with quantitative and qualitative questions, targeted community engagement (five focus groups, six individual interviews) and a photo-elicitation study with a group of high school children.

Research Question

What is history of the relationship between people and place in the Leschenault Estuary District, and what is the relationship in 2012? What were, and what are the place-based social values of the population?

"The Worst Female Character": Criminal Underclass Women In Perth And Fremantle, 1900-1939, Leigh S. Straw

Research outputs 2013

Women charged with offences against good order in Perth and Fremantle from 1900 to 1939 faced institutionalised sexism through the courts, police, and legislation. While men were also criminalised for good order offences, women suffered a double punishment. Charged with drunkenness, being idle and disorderly, and vagrancy, female offenders were further outcast by a public discourse stereotyping them as "bad" women. The extent to which they were able to negotiate and contest this stereotyping was limited, but a subtle negotiation of female identities was possible. This article suggests that female criminal lives offer alternative ways in which to understand women …

Release Of Dissolved Organic Carbon From Seagrass Wrack And Its Implications For Trophic Connectivity, Paul S. Lavery, Kathryn M. Mcmahon, Julia Weyers, Mary C. Boyce, Carolyn Elizabeth Oldham

Research outputs 2013

The export of old leaves and stems (wrack) from seagrass meadows provides a mechanism for trophic connectivity among coastal ecosystems. As little of this wrack is consumed by mesograzers, leached dissolved organic carbon (DOC) may determine the importance of wrack as a trophic subsidy. However, few studies have examined the effect of seagrass type or age on the release of DOC or its bioavailability. We examined the amount and composition of DOC released from different wrack: Posidonia sinuosa, Amphibolis antarctica and the alga Laurencia sp. We then examined the effect of age on DOC leaching from P. sinuosa wrack. The …

Resilience In Same-Sex-Parented Families: The Lived Experience Of Adults With Gay, Lesbian, Or Bisexual Parents, Angharad E. Titlestad, Julie Ann Pooley

Research outputs 2013

Gay, lesbian, and bisexual parents experience stress, as heterocentricism and/or homonegativity permeate the Australian context. Despite challenges faced by these parents and their families, research consistently shows children raised by same-sex parents to be as psychologically healthy, and as socially and academically well-adjusted, as their peers raised in traditional heterosexual-parented families. The ability of these children to flourish despite the challenges they face highlights the resilience of this minority group. Contrary to comparative research, the current study is framed by a phenomenological approach, and utilized narrative methodology to qualitatively explore the lived experiences of the adult children of same-sex parents. …

The Psychological Benefits Of Participating In Group Singing For Members Of The General Public, Marianne D. Judd, Julie Ann Pooley

Research outputs 2013

The last decade has produced a growing number of studies examining the potential psychological benefits of singing in a choir. Studies have tended to focus on the benefits for groups that might be described as marginalized or criminal. In contrast, the current study focused on members of the general public who regularly participate in choral singing. An in-depth qualitative design was utilized to explore the meaning and importance of group singing for 10 participants. Thematic analysis based on an interpretive approach was utilized to analyse the data. Psychological benefits emerged as two themes: individual and group. A third theme, mediating …

Masculinity, Mass Consumerism And Subversive Sex: A Case Study Of Second Life's 'Zeus' Gay Club, Judith A. Elund

Research outputs 2013

This article is a case study of a Second Life region in reference to the prevailing attitudes of sexual conservatism and the growing acceptance of homosexual coupling. The site of Zeus is a contested site of legitimacy in view of tensions regarding masculinity as it applies to sex, sexuality, gender conformity and consumption practices. Furthermore, it is representative of the tensions between an acceptable, albeit conservative gay male identity, and the subversive hyper-sexual and hyper-masculine subject of desire.

Changes To Land Tenure And Pastoral Lease Ownership In Western Australia's Central Rangelands: Implications For Co-Operative, Landscape-Scale Management, Eddie J. Van Etten

Research outputs 2013

The majority of arid and semiarid land in the Western Australian pastoral zone has a long history of livestock grazing within an extensive network of predominantly family-held pastoral leases. A variety of different groups have purchased pastoral leases in the last five decades and, for many, making a profit from pastoralism is no longer a priority. For the central rangelands of Western Australia, these groups have included: government agencies, who have purchased some 9% of pastoral leases by area; private conservation organisations (<1% purchased); aboriginal communities and groups (∼7%); and mining companies (∼13%). The purchases of pastoral leases by government agencies was designed to improve the conservation status of arid-zone ecosystems, and is the first step in a process of changing land tenure to a conservation reserve. This paper summarises the extent and other characteristics of these changes in land tenure and ownership of pastoral leases, and explores the implications for land management and conservation, stemming from these changes. It demonstrates that large areas of contiguous land with no or reduced domestic stocking can now be found in many parts of these rangelands, particularly in the Coolgardie, Yalgoo and Pilbara bio-regions, with some leaseholders actively managing land for the conservation of biodiversity and restoring sites degraded through past over-grazing. In some bio-regions, such land covers considerable proportions of sub-catchments, suggesting that broad-scale conservation management and restoration objectives may be realised. It is argued that to fully realise these objectives requires effective communication and co-ordination between land managers, including sharing of ideas, view-points and resources. In particular, mining companies, now major holders of pastoral leases in Western Australia, can play an important role in contributing to and even facilitating such objectives.

Monitoring Training Loads, Stress, Immune-Endocrine Responses And Performance In Tennis Players, R.V. Gomes, A. Moreira, L. Lodo, Kazunori Nosaka, A.J. Coutts, M.S. Aoki

Research outputs 2013

The study aim was to investigate the effect of a periodised pre-season training plan on internal training load and subsequent stress tolerance, immune-endocrine responses and physical performance in tennis players. Well-trained young tennis players (n = 10) were monitored across the pre-season period, which was divided into 4 weeks of progressive overloading training and a 1-week tapering period. Weekly measures of internal training load, training monotony and stress tolerance (sources and symptoms of stress) were taken, along with salivary testosterone, cortisol and immunoglobulin A. One repetition maximum strength, running endurance, jump height and agility were assessed before and after training. …

Millennial Scale Impact On The Marine Biogeochemical Cycle Of Mercury From Early Mining On The Iberian Peninsula, Oscar Serrano Gras, A. Martinez-Cortizas, M. A. Mateo, H. Biester, R. Bindler

Research outputs 2013

The high-resolution mercury record of a Posidonia oceanica mat in the northwest Mediterranean provides an unprecedented testimony of changes in environmental mercury (Hg) loading to the coastal marine environment over the past 4315 yr BP. The period reconstructed made it possible to establish tentative preanthropogenic background Hg levels for the area (6.8!1.5 ng g–1 in bulk sediments). A small, but significant, anthropogenic Hg increase was identifiable by ~2500 yr BP, in agreement with the beginning of intense mining in Spain. Changes in the record suggest four major periods of anthropogenic Hg pollution inputs to the Mediterranean: first, during the Roman …

Using Digital Representations Of Practical Production Work For Summative Assessment, C. Paul Newhouse

Research outputs 2013

This paper presents the findings of the first phase of a three-year study investigating the efficacy of the digitisation of creative practical work as digital portfolios for the purposes of high-stakes summative assessment. At the same time the paired comparisons method of scoring was tried as an alternative to analytical rubric-based marking because we believed that it was likely that a more holistic approach to scoring would be more appropriate. Researchers created digital representations of the practical submissions of 75 Visual Arts and 82 Design students graduating from secondary school in Western Australia. These digital portfolios were scored using the …

Meta-Analysis Reveals Complex Marine Biological Responses To The Interactive Effects Of Ocean Acidification And Warming, Ben P. Harvey, Dylan Gwynn-Jones, Philippa J. Moore

Research outputs 2013

Ocean acidification and warming are considered two of the greatest threats to marine biodiversity, yet the combined effect of these stressors on marine organisms remains largely unclear. Using a meta-analytical approach, we assessed the biological responses of marine organisms to the effects of ocean acidification and warming in isolation and combination. As expected biological responses varied across taxonomic groups, life-history stages, and trophic levels, but importantly, combining stressors generally exhibited a stronger biological (either positive or negative) effect. Using a subset of orthogonal studies, we show that four of five of the biological responses measured (calcification, photosynthesis, reproduction, and survival, …

Threats And Knowledge Gaps For Ecosystem Services Provided By Kelp Forests: A Northeast Atlantic Perspective, Dan A. Smale, Michael T. Burrows, Philippa J. Moore, Nessa O'Connor, Stephen J. Hawkins

Research outputs 2013

Kelp forests along temperate and polar coastlines represent some of most diverse and productive habitats on the Earth. Here, we synthesize information from >60 years of research on the structure and functioning of kelp forest habitats in European waters, with particular emphasis on the coasts of UK and Ireland, which represents an important biogeographic transition zone that is subjected to multiple threats and stressors. We collated existing data on kelp distribution and abundance and reanalyzed these data to describe the structure of kelp forests along a spatial gradient spanning more than 10° of latitude. We then examined ecological goods and …

A Necrotic Stimulus Is Required To Maximize Matrix-Mediated Myogenesis In Mice, Drew Kuraitis, Maria Grazia Berardinelli, Erik J. Suuronen, Antonio Musaro

Research outputs 2013

Biomaterials that are similar to skeletal muscle extracellular matrix have been shown to augment regeneration in ischemic muscle. In this study, treatment with a collagen-based matrix stimulated molecular myogenesis in an mdx murine model of necrosis. Matrix-treated animals ran ≥ 40% further, demonstrating functional regeneration, and expressed increased levels of myogenic transcripts. By contrast, matrix treatment was unable to induce transcriptional or functional changes in an MLC/SOD1G93A atrophic mouse model. In vitro, satellite cells were cultured under standard conditions, on matrix, in the presence of myocyte debris (to simulate a necrotic-like environment) or with both matrix and necrotic stimuli. Exposure …