Digital Commons Network^™

The Impact Of Religiosity Dimensions And Ethnic Identity On Well-Being In African American Women, Ebony S. Vinson

Theses and Dissertations--Psychology

Religiosity is considered to be an important component of the cultural orientation and worldview of African Americans. African American women, in particular, have been found to be unique in their level of religious devotion and activity compared to other demographic groups but there has been minimal research examining the positive effects of religiosity over time. The purpose of the current study was to investigate the role of religiosity dimensions and ethnic identity in predicting self-esteem, social support, healthy behaviors, and licit drug use in African American women over time. Results indicate that behavioral and cognitive components of religiosity predict different …

Bayesian Analysis Of Parental Drinking Motives And Children's Adjustment, Aaron A. Duke

Theses and Dissertations--Psychology

Harm reduction strategies can mitigate against some of the deleterious effects of alcohol on families. These strategies are most feasible and cost-effective when they can be targeted at those who are most at risk. Previous studies examining the relation between parents’ alcohol use and their children’s psychological adjustment have failed to consider important contextual questions such as drinking motives. The current investigation set out to identify the extent to which parents’ drinking motives predict internalizing and externalizing psychopathology in their children. The investigation consisted of cross sectional analysis of parents’ drinking motives and their children’s adjustment using data from 154 …

Does Botox Buffer The Negative Effects Of Social Rejection?: A Test Of The Facial Feedback Hypothesis, Vicki Sharif

Theses and Dissertations--Psychology

Can a common facial cosmetic procedure buffer against the negative impact of adverse social interactions? This pilot tested the hypothesis that an injection of botulinum toxin (Botox) to the corrugator supercilii muscles used in anger, compared to a placebo injection to the same location, will reduce the impact of social rejection on mood, self-esteem, control, meaningful existence, and aggression. Freezing facial musculature was hypothesized to alter the first physical signal of negative emotional reactions, thereby reducing the impact of social rejection on distress and aggression. This was the first study using Botox to examine the effects of reduced facial feedback …

Expression Of Borderline Personality Disorder Symptoms Across The Ovulatory Cycle: A Multilevel Investigation, Tory A. Eisenlohr-Moul

Theses and Dissertations--Psychology

Borderline Personality Disorder (BPD) is a disabling condition characterized by chronic emotion dysregulation and behavioral impulsivity. Prospective studies that test proposed mechanisms of within-person change in BPD hold the key to improving symptom predictability and control in this disorder. A small body of evidence suggests that fluctuations in estradiol such as those occurring naturally at ovulation during the monthly female reproductive cycle may increase symptoms in women with BPD (DeSoto et al., 2003). Furthermore, there is preliminary evidence that both self-esteem and feelings of social rejection are highest at ovulation, when estradiol peaks (Durante and Hill, 2009; Eisenlohr-Moul et al., …

Characterizing Consumption, Dependence, And The Role Of Glucocorticoids In An Animal Model Of Voluntary Ethanol Consumption, Lynda Sharrett-Field

Theses and Dissertations--Psychology

Alcohol abuse disorders (AUD) represent a serious worldwide health problem with far reaching social, financial, and interpersonal implications. One of the most devastating facets of these disorders is the propensity to relapse following periods of abstinence. Ethanol withdrawal (EWD) is believed to promote relapse by increasing anxiety and craving, and may contribute to the development of cognitive decline associated with long-term dependence. Clinical data suggest that stress also plays a main role in both the development of AUD as well as relapse to drinking. As a physiological stressor, EtOH elevates levels of stress hormones (cortisol in humans, corticosterone (CORT) in …

The Whole Picture: Body Posture Recognition In Infancy, Alyson J. Hock

Theses and Dissertations--Psychology

Holistic image processing is tied to expertise and is characteristic of face and body processing by adults. Infants process faces holistically, but it is unknown whether infants process body information holistically. In the present study, we examined whether infants discriminate changes in body posture holistically. Body posture is an important nonverbal cue that signals emotion, intention, and goals of others even from a distance. In the current study, infants were tested for discrimination between body postures that differ in limb orientations in three conditions: in the context of the whole body, with just the limbs that change orientation, or with …

Marital Conflict And Pubertal Timing: Stress And Security As Mediators Of Associations, Eric A. Haak

Theses and Dissertations--Psychology

The timing of pubertal development has important mental and physical health consequences. Individuals who enter puberty off-time are at greater risk for psychological disorders, social difficulties, and physical morbidity. One variable associated with early pubertal development is marital conflict. Life History Theory proposes that marital conflict signals an unreliable environment and promotes advanced pubertal timing to enhance reproductive fitness. Such calibrations allow individuals to unconsciously invest more resources in reproduction, following a quantity over quality approach. Despite research supporting the role of marital conflict in early-onset puberty, research has struggled to find a mechanism for this relationship. The current study …

Economics And/Of Science: The Meaning(S) Of Financial Bias And The Ideal Of Interest-Free Science In Law, David S. Caudill

SMU Science and Technology Law Review

No abstract provided.

Their Brains On Google: How Digital Technologies Are Altering The Millennial Generation's Brain And Impacting Legal Education, Kari Mercer Dalton

SMU Science and Technology Law Review

No abstract provided.

Reasonable Efforts And Parent-Child Reunification, Raymond C. O'Brien

Scholarly Articles

Among the increasing number of federal statutes impacting family law two continue to impact child permanency and parental rights. First, the Adoption Assistance and Child Welfare Act of 1980 mandates that state courts find that the state child welfare agency made reasonable efforts to reunite a dependent child with his or her parents prior to termination of parental rights. The child is dependent because a state court held that there was sufficient clear and convincing evidence to remove the child from the parents’ home. Often that evidence results from parental poverty, mental or physical disability, or the parents are undereducated …

You Have The Right To Remain Silent: Does The U.S. Constitution Require Public Affirmation Of Same-Sex Marriage?, Robert A. Destro

Scholarly Articles

The political and legal campaign for marriage equality rests on the proposition that the Constitution of the United States requires communal recognition of committed, same-sex relationships. The text, structure, and history of the amended Constitution, however, support precisely the opposite conclusion: i.e., that neither the United States nor any state may compel any community, association, or individual to affirm (by word, deed, or policy) the hotly disputed propositions about human sexuality that lie at the core of the debate. Nor can it plausibly be argued that any part of the Constitution requires any person, association, or polity to remain discreetly …

Mechanical Properties Of Human Amniotic Fluid Stem Cells Using Nanoindentation, Ashkan Aryaei, Ambalangodage Jayasuriya

Faculty Publications

The aim of this study was to obtain nanomechanical properties of living cells focusing on human amniotic fluid stem (hAFS) cell using nanoindentation techniques. We modified the conventional method of atomic force microscopy (AFM) in aqueous environment for cell imaging and indentation to avoid inherent difficulties. Moreover, we determined the elastic modulus of murine osteoblast (OB6) cells and hAFS cells at the nucleus and cytoskeleton using force–displacement curves and Hertz theory. Since OB6 cell line has been widely used, it was selected to validate and compare the obtained results with the previous research studies. As a result, we were able …

Bioassay Guided Fractionation Of American Ginseng. A Hexane Fraction Of American Ginseng Suppresses Colitis And Associated Colon Cancer. Mechanism Of Action., Deepak Poudyal

Theses and Dissertations

Inflammatory Bowel Disease (IBD) [Ulcerative colitis (UC) and Crohn's Disease (CD)] is a group of chronic disorders of unknown etiology characterized by inflammation in the gastrointestinal tract associated with a high colon cancer risk. UC is characterized by periods of active disease ("flare-ups"), followed by periods when the disease is inactive ("remission"). The end result is an abnormal immune response with repeated episodes of colonic inflammation. Conventional treatment of UC by aminosalicylates, TNFα inhibitors, and steroids have modest effects, and come with a high risk of side effects including dyspeptic symptoms, gastric ulceration and sometimes hospitalization and deaths. Because of …

The Flying University, Catherine Friesen

Theses and Dissertations

The Flying University is solo theater performance framed as an academic lecture about Marie Curie and her discovery of radium, delivered to a group of women who have gathered in secret to further their education. As the lecture proceeds, the professor brings in her own research based on a study of Esther Horsch (1905-1991) who lived on a farm in central Illinois. She introduces data from Esther's journals, personal memories, and dreams about Esther's life. The professor's investigation of radium plays at the intersections of magical and mundane, decay and the transformation of life, and the place of ambition in …

The Relationship Of South Carolina Teachers' Work-Related Stress With Years Of Experience, Feelings And Coping Strategy, Michelle Munnell

Theses and Dissertations

Background. Stress has been found to affect workers in various occupations, and teaching appears particularly stressful. Work-Related Stress (WRS) affects teachers and people with whom they interact. Previous research suggests WRS may be related to characteristics including teaching experience, feelings, and coping strategy. Objective. The purpose of this study was to investigate further the relationship of teacher stress, while expanding the investigation in several areas: utilizing a different geographic population, broadening the focus to generic WRS, and including teachers with less experience. Current model builds on Kyriacou and Sutcliffe's (1978) and Tolbert's (2007) teacher stress models. This study examined relationships …

Writing Across Differences: Afro-Germans, Gender, And Diaspora, 1970s-1990s, Tiffany Nicole Florvil

Theses and Dissertations

My dissertation, "Writing Across Differences: Afro-Germans, Gender, and Diaspora, 1970s-1990s," explores the birth of the Afro-German movement, including its two organizations: The Initiative of Black Germans (Initiative Schwarze Deutsche, ISD) and Afro-German Women (Afro-deutsche Frauen, ADEFRA) in West and then reunified Germany. In it, I uncover the efforts of Black Germans to organize a diasporic and literary movement to confront discriminatory discourses and practices that simultaneously ignored them and positioned them as "Others" in postwar German society. Through their diverse literature and coordinated events, Black Germans enacted membership in the African diaspora, articulating and claiming an identity that supported a …

Working Memory-Learning Condition Interactions: Proficiency In L2 Russian Under Naturalistic And Formal Learning Conditions, Marc Canner

Theses and Dissertations

The purpose of this dissertation was to examine the relationships between working memory (WM) and three commonly used learning strategies or conditions in the nature of proficiency among adult L2 Russian learners. Based on the aptitude-learning condition interaction framework articulated by Robinson (2002b), the study identifies two types of relationships between the fixed variables of working memory and learning condition, and four variables related to second language proficiency (SLP) in Russian: accuracy, fluency, overall general proficiency or `native-likeness', and the occurrence of potentially fossilized forms in speech. Three main learning contexts were identified, including strictly naturalistic conditions resulting from immersion …

Chemical Leaching Methods And Measurements Of Marine Labile Particulate [Fe] And Δ56fe, Brandi Nicole Revels

Theses and Dissertations

Iron (Fe) is an essential nutrient for life. However its low solubility in the seawater limits primary productivity in many regions of the world's oceans. Dissolved phase Fe (<0.4μm) has traditionally been considered the most biologically accessible form, but, recent studies suggest the particulate phase (>0.4μm) may contain an important, labile reservoir of Fe that may also be available to phytoplankton. Although valuable, Fe concentrations of particles alone do not provide complete evidence about the sources of particulate Fe to the ocean, or the extent particulate iron may be accessed by phytoplankton. Fe isotopes may help to reveal the biogeochemical cycling of particulate Fe. This study aims to develop a chemical leaching technique that accesses the …

Building Resiliency: Supporting Elementary School Students Through Parental Bereavement, Sandra Kerr Ray

Theses and Dissertations

This study employed qualitative methods to learn what understandings, practices, and interventions were used by educators from one elementary school to support bereaved children in the classroom and as members of a school community. Educators reported uncertainty about how children grieve, how to talk with children about a deceased parent, how to talk with the bereaved child’s peers about parental death, and how to balance the bereaved child’s emotional and academic needs. Educators were also uncertain about how to recognize and intervene when a parental death was remote in time and the child’s grief response was attenuated (e.g., anxiety, disengagement, …

Differential Gene Expression Patterns In Hpv-Positive And Hpv-Negative Oropharyngeal Carcinomas, Swati Tomar

Theses and Dissertations

Head and neck (HN) cancer is the fifth most prevalent malignancy worldwide with 90% of them categorized as squamous cell carcinomas (SCC). Carcinomas of the oropharynx, pharynx and the oral cavity, comprise a subset of HNSCC and are referred to as oropharyngeal squamous cell carcinomas (OPSCC). Up to 60% of OPSCC and 25% of HNSCC are positive for high-risk human papillomavirus (HR-HPV), primarily HPV16. HPV positive and HPV negative OPSCC’s are molecularly and biologically distinct with differences in risk factors, age of presentation and clinical behavior. The precise molecular signatures of each have been well studied with respect to gene …

Insects As Indicators Of Environmental Stress, De Anna Estella Beasley

Theses and Dissertations

In the face of climate change-related events and anthropogenic disturbances, understanding the impacts of these events on species richness, abundance and distribution is important for us to mitigate biodiversity loss and better predict consequences for the environment and for human life. Insects are excellent models for understanding the consequences of environmental stress due to the sensitivity of their development and behavior. The overall focus of my dissertation research is the investigation of fluctuating asymmetry and oviposition behavior as indicators of environmental stress. My research includes a meta-analysis of published literature, and empirical research that was part of a collaborative initiative …

The Reproductive Ecology Of Plethodontid Salamanders In The South Carolina Inner Coastal Plain, Heather Rena Oswald

Theses and Dissertations

Nest- site selection is a critical process in the life history of amphibians, directly influencing offspring survival and parental fitness. When and where an amphibian chooses to nest is strongly influenced by a range of environmental cues. We monitored plethodontid salamander breeding behavior in seepage wetlands in the South Carolina inner Coastal Plain. Seepage wetlands are ideal for monitoring semiaquatic salamander breeding, because they provide habitat for both larval and adult salamanders while having relatively predictable, constant water temperatures and presence year round. We observed the breeding phenology of three sympatric salamanders (Eurycea cirrigera, Desmognathus auriculatus, and Pseudotriton ruber) in …

Microencapsulation Of A Connexin-43 Mimetic Peptide As A Novel Wound Healing Agent In An Ocular Injury Model, Keith Brian Moore

Theses and Dissertations

Corneal transplantation and related surgical procedures are areas of tissue replacement which have seen promising advances. Currently, cornea transplants are one of the most common surgical procedures, with approximately 40,000 occurring each year in the United States. Still, problems exist with a 20% rejection rate, post surgical infections, and the need for a constant supply of donors. The ability to safely and quickly heal and regenerate corneal epithelia fills an area of advancement in regenerative medicine, with implications reaching beyond the scope of vision therapies toward healing of a wide range of tissues and wounds. In vivo corneal wounds were …

Gold Nanoparticles And Peptoids As Novel Inhibitors Of Amyloid Beta Aggregation In Alzheimer's Disease, Kelly Ann Moore

Theses and Dissertations

In 2012 it was estimated that one in every nine Americans over the age of 65 has Alzheimer's disease (AD) (1). These patients experience gradual loss of memory, cognition, and behavioral stability eventually leading to death (2). These symptoms were first described in 1906 by Alois Alzheimer and now are the classic signs of the number one neurodegenerative disease today. Current AD therapies delay or mitigate the symptoms associated with AD to improve the quality of life for the patient; however, there is currently no cure for those that have been diagnosed. In order to develop a possible treatment for …

Effect Of Physiological Oxygen Levels On Osteogenic Differentiation Of Adipose-Derived Stem Cells, Suchit Sahai

Theses and Dissertations

Regenerative medicine presents exciting strategies for healing critical-size bone defects through the implantation of cells and biocompatible scaffolds. Most in vitro studies are performed in atmospheric oxygen conditions (~20%), which do not accurately mimic the CSD microenvironment. Due to damage to the vasculature at CSDs, oxygen levels fall into the hypoxic range (<5%), which can impact viability, proliferation and differentiation of the cells employed for bone regeneration. Understanding the cellular responses to hypoxia has grown primarily from study of individual molecular factors. The master regulator of adaptive responses to low oxygen availability is the nuclear factor, hypoxia-inducible factor-1. HIF-1 is a heterodimeric protein, stable below 6% O2 condition in the nucleus and has been shown to play a role in angiogenic-osteogenic coupling. We have developed a responsive, fluorescent, hypoxia detection system and determined whether HIF activity can be tracked in both 2-D and 3-D cultures. Adipose-derived stem cells (ASCs) were selected due to their broad utilization in tissue engineering strategies and characterized the influence of HIF signaling on its phenotype. The work done identified that of hypoxia impaired osteogenic differentiation of ASCs in both 2-D and 3-D cultures and HIF-1 did not mediate this effect. Ischemic preconditioning (IPC) strategy and varied protocols used represents a clinically feasible manipulation of cell preparation to help the survival of implanted ASCs and accelerate osteogenic differentiation at physiological oxygen levels.

A New Method For The Comparison Of Survival Distributions, Jaymie Shanahan

Theses and Dissertations

The assessment of overall homogeneity of time-to-event curves is a key element in survival analysis in biomedical research. The currently commonly used testing methods, e.g. log-rank test, Wilcoxon test, and Kolmogorov-Smirnov test, may have a significant loss of statistical testing power under certain circumstances. In this thesis we replicate a testing method (Lin & Xu, 2009) that is robust for the comparison of the overall homogeneity of survival curves based on the absolute difference of the area under the survival curves using normal approximation by Greenwood's formula, and propose a new weight component to their test statistic. The weight component …

Enantioselective Hydrogenation Of Α-Methylcinnamic Acid Over Pd/Al2o3: A Spectroscopic And Kinetic Study, Xiaojing Sun

Theses and Dissertations

Hydrogenation of C=C in α-methylcinnamic acid (MCA) is studied by both kinetic and spectroscopic method. Kinetic study was in a semi-batch reactor. The reaction activity is strongly solvent dependent, while selectivity remains almost unaffected. The reaction is zero order in hydrogen pressure and first order in MCA. The presence of cinchonidine does not affect the reaction order with respect to either acid or H2 pressure, but has a significant inhibiting effect on the reaction rate. The catalyst exhibits stable activity during the reaction with no sign of deactivation. The adsorption and hydrogenation in dichloromethane, isopropanol and 1, 4-Dioxane over the …

Novel T(5;19) Translocation In A Patient With Pdgfrb Associated Chronic Leukemia: Implications For Treatment Strategy., Joel D Provenzano, J Phillip Kuebler

Oncology Articles

Myeloproliferative disorders are variable disorders, based on the genetic abnormality present and the cell line progenitors that are affected. In this case, we discuss a novel gene translocation in the subset of PDGFRB mutations, first seen with prominent hyperbasophilia. This case demonstrates the possibility for lower therapeutic doses of imatinib mesylate than previously reported, in order to control leukocyte counts and reverse the genetic mutation.

Rewriting The Human: Death Anxiety And Posthuman Vision In Literature Since 1945, John Allen Brooks

Theses and Dissertations

ISS_para>The technology-driven years following the close of World War II provided a new lens through which the human subject could be rethought and, theoretically, improved: no longer did physical and mental shortcomings have to limit the capacity of the individual. The atomic bomb and Colossus computer, though destructive forces, pushed scientists and philosophers to consider new models of the human, including flesh/machine amalgamation and reinscription as downloadable, digital information. While these posthuman constructions promised to distance the human from its material shortcomings, especially its vulnerability to bodily decay and death, they encountered significant resistance in the twentieth century.

By …

Selling The Country’S Secrets: Willa Cather’S Eco(Self)Criticism In My Antonia And The Professor’S House, Elizabeth Nicole Morgan

Theses and Dissertations

This study considers Willa Cather's ecological consciousness as a writer of place, particularly in My Antonia and The Professor's House. In these two works, Cather's narrative distance provides her with the room to investigate the relationship between humans and their environments. Jim Burden, Godfrey St. Peter, and Tom Outland all exploit their environments to greater or lesser extents based on their way of seeing the world, which Cather draws attention to through her careful characterization and narrative distance. In each narrative, Cather forces readers to recognize the environmental consequences of egocentric vision, and the way such vision can be sustained …