Digital Commons Network^™

Patterns In Nature Forming Patterns In Minds : An Evaluation Of An Introductory Physics Unit, Christopher Ryan Sheaffer

Dissertations and Theses

Educators are increasingly focused on the process over the content. In science especially, teachers want students to understand the nature of science and investigation. The emergence of scientific inquiry and engineering design teaching methods have led to the development of new teaching and evaluation methods that concentrate on steps in a process rather than facts in a topic. Research supports the notion that an explicit focus on the scientific process can lead to student science knowledge gains. In response to new research and standards many teachers have been developing teaching methods that seem to work well in their classrooms, but …

Volume 5, Chapter 3-3: Fine Arts: Literature, Janice M. Glime

Bryophyte Ecology Subchapters

No abstract provided.

Shared Responsibility In A Multispecies Playground, Marcus Baynes-Rock

Between the Species

While conducting research on urbanised hyenas in Harar, Ethiopia, I was approached by a young hyena named Willi. In contrast to other hyenas, who tolerated my presence but otherwise had little interest in me, Willi insisted on some kind of engagement. Through biting, chase play, combing, following and standing by one other, Willi and I went beyond our species limitations and created an improvised intersubjectivity based on a will to understand. However, our friendship led to some harmful consequences for which I felt responsible. This led me to question the ethics of engagement with non-humans: if unforeseen harms can result …

Curbing Intercountry Adoption Abuses Through The Alien Tort Statute, William Giacofci

Roger Williams University Law Review

No abstract provided.

Relationship Between Mindfulness-Based Stress Reduction And Immune Function In Cancer And Hiv/Aids, Rachel L. Zeichner, Jeffery L. Kibler, Simon B. Zeichner

Faculty Articles

Objective: Chronic stress is widespread, and is detrimental to immune functioning and to overall physical and emotional health. These effects may be potentiated in patients with chronic illness, as high levels of chronic stress are common in this population. Numerous studies support the efficacy of mindfulness-based stress reduction (MBSR) in improving psychological functioning. If a strong relationship is found between MBSR and immune function, then MBSR may be implemented as a strategy to improve immune functioning and overall well-being.

Methods: In the present review paper, the relationship between MBSR and immune function is evaluated. Empirical studies measuring immune markers as …

The Living Dead: Why One Species' Interference With Development May Undermine The Entire Endangered Species Act, Melissa Chalek

Roger Williams University Law Review

No abstract provided.

Greed Is Good, For Patients: How The Biotechnology Industry Saves Lives, One Gene Patent At A Time, Nikki Buck

Northwestern Journal of Technology and Intellectual Property

Greed is Good, for Patients: How the Biotechnology Industry Saves Lives, One Gene Patent at a Time

From Prometheus To Myriad To Classen, What A Messy Subject Matter: A Review On Recent Life Science Method Patent Cases, Rui Xu

Northwestern Journal of Technology and Intellectual Property

From Prometheus to Myriad to Classen, What a Messy Subject Matter: A Review on Recent Life Science Method Patent Cases

Retired National Football League Players' Perceptions Of Financial Decisions Made: A Phenomenological Study, John Karaffa

Faculty Dissertations

The purpose of this qualitative phenomenological research study was to examine the lived experiences and perceptions of 25 former National Football League (“NFL”) players regarding the financial decisions they made when active as players for information that could lead to an appropriate model for making good financial decisions. Determined in the qualitative phenomenological study were the influential factors identified by the participants in the study that focused on financial decisions made by former NFL players. The study revealed five themes: (1) wealth enablers, (2) wealth killers, (3) challenges, (4) attitudes, and (5) wealth weak spots. The results of the study …

A General Regression Framework For A Secondary Outcome In Case-Control Studies, Eric J. Tchetgen Tchetgen

Harvard University Biostatistics Working Paper Series

No abstract provided.

An Ethical Analysis Of Reproductive Tourism And Technologies From A Multi-Dimensional Lens, Lynnette Nathalie Lyzwinski Ba, M.Phil. Candidate

Journal of Health Ethics

The permeation of reproductive technologies and reproductive tourism across boundaries of the globe has resulted in a global debate surrounding their moral and ethical viability. The purpose of this paper is to objectively assess the morality inherent in reproductive technologies by examining the perspectives of women seeking them and subjects providing them and by analyzing multiple ethical lenses. It will first aim to determine whether these technologies should be universally accessible to all couples within a given country and whether the private provision of these treatments creates unethical inequities in accessibility. It will then seek to determine whether crossing borders …

Uab Patent, Researcher Key To Breakthrough Named A Top Innovation Of 2012, Jim Bakken

Browse All News

No abstract provided.

Wade V. Taylor Appellant's Brief Dckt. 40142

Idaho Supreme Court Records & Briefs, All

No abstract provided.

State V. Vaughn Appellant's Brief Dckt. 39526

Not Reported

No abstract provided.

Choosing The Genetics Of Our Children: Options For Framing Public Policy, Girard Kelly

Santa Clara High Technology Law Journal

This paper examines the controversial topic of choosing our children’s genes through human germ-line manipulation otherwise known as Inheritable Genetic Modification (IGM) with current Assisted Reproductive Technologies (ARTs) and future Reproductive Genetic Biotechnologies (RGBs) such as genetic engineering. The purpose of the paper is to examine these potentially revolutionary biotechnologies and the emerging social, and bioethical perspectives advanced by both proponents and opponents—in the context of the legal and regulatory policies impacting ARTs and RGBs. Lastly, the paper recommends new public policy and regulatory frameworks to support future research and development of RGBs by providing legislative guidance to policymakers to …

Object Detection And Recognition In Natural Settings, George William Dittmar

Dissertations and Theses

Much research as of late has focused on biologically inspired vision models that are based on our understanding of how the visual cortex processes information. One prominent example of such a system is HMAX [17]. HMAX attempts to simulate the biological process for object recognition in cortex based on the model proposed by Hubel & Wiesel [10]. This thesis investigates the ability of an HMAX-like system (GLIMPSE [20]) to perform object-detection in cluttered natural scenes. I evaluate these results using the StreetScenes database from MIT [1, 8]. This thesis addresses three questions: (1) Can the GLIMPSE-based object detection system replicate …

Analysis Of Small Molecule Ligands Targeting The Hiv-1 Matrix Protein-Rna Binding Site, Ayna Alfadhli, Henry Mcnett, Jacob Eccles, Seyram Tsagli, Colleen Noviello, Rachel Sloan, Claudia S. López, David H. Peyton, Eric Barklis

Chemistry Faculty Publications and Presentations

The matrix (MA) domain of the HIV-1 PrGag protein directs PrGag proteins to assembly sites at the plasma membrane by virtue of its affinity to the phospholipid, phosphatidylinositol-4,5-bisphosphate (PI(4,5)P₂). MA also binds to RNA at a site that overlaps its PI(4,5)P₂ site, suggesting that RNA binding may protect MA from associating with inappropriate cellular membranes prior to PrGag delivery to the PM. Based on this, we have developed an assay in which small molecule competitors to MA-RNA binding can be characterized, with the assumption that such compounds might interfere with essential MA functions and help elucidate additional features of MA …

Dual-Tracer Background Subtraction Approach For Fluorescent Molecular Tomography, Kenneth M. Tichauer, Robert W. Holt, Fadi El-Ghussein, Scott C. Davis, Kimberly S. Samkoe, Jason R. Gunn, Frederic Leblond, Brian W. Pogue

Dartmouth Scholarship

Diffuse fluorescence tomography requires high contrast-to-background ratios to accurately reconstruct inclusions of interest. This is a problem when imaging the uptake of fluorescently labeled molecularly targeted tracers in tissue, which can result in high levels of heterogeneously distributed background uptake. We present a dual-tracer background subtraction approach, wherein signal from the uptake of an untargeted tracer is subtracted from targeted tracer signal prior to image reconstruction, resulting in maps of targeted tracer binding. The approach is demonstrated in simulations, a phantom study, and in a mouse glioma imaging study, demonstrating substantial improvement over conventional and homogenous background subtraction image reconstruction …

Professional Development Strategies That Promote Science Inquiry Teaching And Learning, Steven Kerlin

Journal of Excellence in College Teaching and Learning

The recently released Framework for K-12 Science Education (National Research Council, 2012) calls for science education to addresses weaknesses in current science education of unorganized learning progressions, a focus on a breadth of discrete facts, and a lack of experiences in how science is actually done. Teacher professional development in inquiry science teaching and learning is one way to address these current issues in science education effectively. Higher education faculty have been one of the major groups of providers of teacher professional development programs. Many of these professional development programs have been delivered in short-term workshops and traditionally focused on …

Staff Council Employee Life Committee Meeting, 1/3/2013, Unm Staff Council

UNM Staff Council

No abstract provided.

Volume 5, Chapter 2-1: Medical Uses: Medical Conditions, Janice M. Glime

Bryophyte Ecology Subchapters

No abstract provided.

A Review Of Radio Frequency Identification Technologies And Impacts On The Hospital Supply Chain: 2002–2012, Alberto Coustasse, Shane Tomblin, Chelsea Slack

Management Faculty Research

Supply costs are the second largest expenditure in hospitals, accounting for more than one third of the average operating budget. RFID technology can reduce these costs, improve patient safety, and supply chain management by increasing the ability to track and locate equipment, as well as monitoring theft prevention, distribution management, and patient billing. Findings of this study have shown that the application of RFID on medical equipment and supplies have resulted in efficiency increase in healthcare with lower costs and increased quality services. Even though the cost of RFID implementation is decreasing, the total expenditures are still significant and the …

Wrangling Phosphoproteomic Data To Elucidate Cancer Signaling Pathways, Mark L. Grimes, Wan-Jui Lee, Laurens Van Der Maaten, Paul Shannon

Biological Sciences Faculty Publications

The interpretation of biological data sets is essential for generating hypotheses that guide research, yet modern methods of global analysis challenge our ability to discern meaningful patterns and then convey results in a way that can be easily appreciated. Proteomic data is especially challenging because mass spectrometry detectors often miss peptides in complex samples, resulting in sparsely populated data sets. Using the R programming language and techniques from the field of pattern recognition, we have devised methods to resolve and evaluate clusters of proteins related by their pattern of expression in different samples in proteomic data sets. We examined tyrosine …

Jefferson Digital Commons Quarterly Report: October-December 2013, Daniel G. Kipnis, Msi

Jefferson Digital Commons Reports

Year end quarterly report for the Jefferson Digital Commons. Includes statistics, pie chart breaking down types of resources indexed in the JDC, comments from users, highlighted new assets in the collection.

Objectively Measured Sedentary Behavior In Preschool Children: Comparison Between Montessori And Traditional Preschools, Wonwoo Byun, Steven N. Blair, Russell R. Pate

Faculty Publications

Background: This study aimed to compare the levels of objectively-measured sedentary behavior in children attending Montessori preschools with those attending traditional preschools.

Methods: The participants in this study were preschool children aged 4 years old who were enrolled in Montessori and traditional preschools. The preschool children wore ActiGraph accelerometers. Accelerometers were initialized using 15-second intervals and sedentary behavior was defined as/15-second. The accelerometry data were summarized into the average minutes per hour spent in sedentary behavior during the in-school, the afterschool, and the total-day period. Mixed linear regression models were used to determine differences in the average time spent in …

January Exhibits At Merwin And Wakeley Galleries, Sherry Wallace

News and Events (Discontinued Series)

No abstract provided.

Long-Term Upregulation Of Inflammation And Suppression Of Cell Proliferation In The Brain Of Adult Rats Exposed To Traumatic Brain Injury Using The Controlled Cortical Impact Model, Sandra A. Acosta, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Bethany Grimmig, David M. Diamond, Paul R. Sanberg, Paula C. Bickford, Yuji Kaneko, Cesario V. Borlongan

Psychology Faculty Publications

The long-term consequences of traumatic brain injury (TBI), specifically the detrimental effects of inflammation on the neurogenic niches, are not very well understood. In the present in vivo study, we examined the prolonged pathological outcomes of experimental TBI in different parts of the rat brain with special emphasis on inflammation and neurogenesis. Sixty days after moderate controlled cortical impact injury, adult Sprague-Dawley male rats were euthanized and brain tissues harvested. Antibodies against the activated microglial marker, OX6, the cell cycle-regulating protein marker, Ki67, and the immature neuronal marker, doublecortin, DCX, were used to estimate microglial activation, cell proliferation, and neuronal …

The Telomere Capping Complex Cst Has An Unusual Stoichiometry, Makes Multipartite Interaction With G-Tails, And Unfolds Higher-Order G-Tail Structures, Neal F. Lue, Ruobo Zhou, Lidia Chico, Ninghui Mao, Olga Steinberg-Neifach, Taekjip Ha

Publications and Research

The telomere-ending binding protein complex CST (Cdc13-Stn1-Ten1) mediates critical functions in both telomere protection and replication. We devised a co-expression and affinity purification strategy for isolating large quantities of the complete Candida glabrata CST complex. The complex was found to exhibit a 2∶4∶2 or 2∶6∶2 stoichiometry as judged by the ratio of the subunits and the native size of the complex. Stn1, but not Ten1 alone, can directly and stably interact with Cdc13. In gel mobility shift assays, both Cdc13 and CST manifested high-affinity and sequence-specific binding to the cognate telomeric repeats. Single molecule FRET-based analysis indicates that Cdc13 and …

Performance Analysis Of Palm, Jatropha And Moringa Biodiesels In A Diesel Engine / Md. Mofijur Rahman, Rahman Md. Mofijur

Student Works (2010-2019)

The global energy consumption is expected to grow in a faster rate than the population growth. By 2030, an increase of 53% of global energy consumption and 39% of greenhouse gases emissions from fossil fuels are anticipated. Therefore, it has become a global agenda to develop clean alternative fuels which are domestically available, environmentally acceptable and technically feasible. As an alternative fuel, biodiesel seems as one of the best choices among other sources due to its environment friendly aspect and similar functional properties as diesel fuel. This research aims to produce biodiesel from some edible and non-edible oils that are …

Revisiting The Evolution Of Mouse Line-1 In The Genomic Era, Akash Sookdeo, Crystal M. Hepp, Marcella A. Mcclure, Stéphane Boissinot

Publications and Research

Background LINE-1 (L1) is the dominant category of transposable elements in placental mammals. L1 has significantly affected the size and structure of all mammalian genomes and understanding the nature of the interactions between L1 and its mammalian host remains a question of crucial importance in comparative genomics. For this reason, much attention has been dedicated to the evolution of L1. Among the most studied elements is the mouse L1 which has been the subject of a number of studies in the 1980s and 1990s. These seminal studies, performed in the pre-genomic era when only a limited number of L1 sequences …