Digital Commons Network^™

Prioritizing Pacific Salmon Stocks For Conservation: Response To Allendorf Et Al., Thomas C. Wainwright, Robin Waples

United States Department of Commerce: Staff Publications

Recently, Allendorf et al. (1997) proposed criteria intended to guide prioritization of Pacific salmon (Oncorhynchus spp.) stocks for conservation. The authors provide a good summary of several important aspects of extinction risk, and we agree with many of their points: (1) prioritization is useful and may help focus conservation efforts; (2) a two-pronged approach that identifies the relative risk faced by different populations and evaluates their significance is a reasonable strategy; (3) risks should be evaluated based on multiple criteria; and (4) specific threshold values for these criteria promote objectivity and can assist in decision making. We also recognize …

A Few Inconvenient Truths About Michael Crichton's State Of Fear: Lawyers, Causes, And Science, Lea B. Vaughn

Seton Hall Journal of Sports and Entertainment Law

No abstract provided.

The Nucleus 2012-2013, Rrosalie A. Richards

Science Education Center

No abstract provided.

Chimeric Isoprenoid Synthases And Uses Thereof, Joe Chappell, Kyoungwhan Back

Plant and Soil Sciences Faculty Patents

Provided is a chimeric isoprenoid synthase polypeptide including a first domain from a first isoprenoid synthase joined to a second domain from a second, heterologous, isoprenoid synthase, whereby the chimeric isoprenoid synthase is capable of catalyzing the production of isoprenoid reaction products that are not produced in the absence of the second domain of the second, heterologous, isoprenoid synthase. Also provided is a chimeric isoprenoid synthase polypeptide including an asymmetrically positioned heterologous domain, whereby the chimeric isoprenoid synthase is capable of catalyzing the production of isoprenoid reaction products that are not produced when the domain is positioned at its naturally-occurring …

Minutes, Arts & Sciences Academic Affairs Committee Meeting, Tuesday, January 15, 2013, Arts & Sciences Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.

Lipophilic Stinging Nettle Extracts Possess Potent Anti-Inflammatory Activity, Are Not Cytotoxic And May Be Superior To Traditional Tinctures For Treating Inflammatory Disorders., Tyler A. Johnson, Johann Sohn, Wayne D Inman, Leonard F. Bjeldanes, Keith Rayburn

Natural Sciences and Mathematics | Faculty Scholarship

Extracts of four plant portions (roots, stems, leaves and flowers) of Urtica dioica (the stinging nettle) were prepared using accelerated solvent extraction (ASE) involving water, hexanes, methanol and dichloromethane. The extracts were evaluated for their anti-inflammatory and cytotoxic activities in an NF-κB luciferase and MTT assay using macrophage immune (RAW264.7) cells. A standardized commercial ethanol extract of nettle leaves was also evaluated. The methanolic extract of the flowering portions displayed significant anti-inflammatory activity on par with a standard compound celastrol (1) but were moderately cytotoxic. Alternatively, the polar extracts (water, methanol, ethanol) of the roots, stems and leaves displayed moderate …

Hd-Cnv: Hotspot Detector For Copy Number Variants., Jenna L Butler, Marjorie Elizabeth Osborne Locke, Kathleen A Hill, Mark Daley

Brain and Mind Institute Researchers' Publications

SUMMARY: Copy number variants (CNVs) are a major source of genetic variation. Comparing CNVs between samples is important in elucidating their potential effects in a wide variety of biological contexts. HD-CNV (hotspot detector for copy number variants) is a tool for downstream analysis of previously identified CNV regions from multiple samples, and it detects recurrent regions by finding cliques in an interval graph generated from the input. It creates a unique graphical representation of the data, as well as summary spreadsheets and UCSC (University of California, Santa Cruz) Genome Browser track files. The interval graph, when viewed with other software …

Discontinuous Parameter Estimates With Least Squares Estimators, J. L. Mead

Mathematics Faculty Publications and Presentations

We discuss weighted least squares estimates of ill-conditioned linear inverse problems where weights are chosen to be inverse error covariance matrices. Least squares estimators are the maximum likelihood estimate for normally distributed data and parameters, but here we do not assume particular probability distributions. Weights for the estimator are found by ensuring its minimum follows a χ² distribution. Previous work with this approach has shown that it is competitive with regularization methods such as the L-curve and Generalized Cross Validation (GCV) [20]. In this work we extend the method to find diagonal weighting matrices, rather than a scalar regularization …

Loss Of Dystrophin Staining In Cardiomyocytes: A Novel Method For Detection Early Myocardial Infarction, Satwat Hashmi, Suhail Al-Salam

Department of Biological & Biomedical Sciences

Myocardial infarction (MI) is the most frequent diagnosis made in majority of sudden death cases subjected to clinical and medicolegal autopsies. When sudden death occurs at a very early stage of MI, traditional macroscopic examination, or histological stains cannot easily detect the myocardial changes. For this reason we propose a new method for detecting MI at an early stage. Murine model of MI was used to induce MI through permanent ligation of left anterior descending branch of left coronary artery. Five groups of C57B6/J mice were used for inducing MI, which includes 20 minutes, 30 minutes, one hour, four hours …

Synthesis And Cellular Studies Of Polyamine Conjugates Of A Mercaptomethyl-Carboranylporphyrin, N. V.S.Dinesh K. Bhupathiraju, M. Graça H. Vicente

Faculty Publications

Seven polyamine conjugates of a tri(p-carboranylmethylthio) tetrafluorophenylporphyrin were prepared in high yields by sequential substitution of the p-phenyl fluoride of tetrakis(pentafluorophenyl)porphyrin (TPPF), and investigated as boron delivery agents for boron neutron capture therapy (BNCT). The polyamines used were derivatives of the natural-occurring spermine with different lengths of the carbon chains, terminal primary amine groups and, in two of the conjugates, additional aminoethyl moieties. A tri(polyethylene glycol) conjugate was also synthesized for comparison purposes. The polyamine conjugates showed low dark cytotoxicity (IC50 >400 μM) and low phototoxicity (IC50 >40 μM at 1.5 J/cm 2). All polyamine conjugates, with one exception, showed …

Synthesis And Structure-Activity Relationship Of Piperidine-Derived Non-Urea Soluble Epoxide Hydrolase Inhibitors, Stevan Pecic, Svetlana Pakhomova, Marcia E. Newcomer, Christophe Morisseau, Bruce D. Hammock, Zhengxiang Zhu, Alison Rinderspacher, Shi Xian Deng

Faculty Publications

A series of potent amide non-urea inhibitors of soluble epoxide hydrolase (sEH) is disclosed. The inhibition of soluble epoxide hydrolase leads to elevated levels of epoxyeicosatrienoic acids (EETs), and thus inhibitors of sEH represent one of a novel approach to the development of vasodilatory and anti-inflammatory drugs. Structure-activities studies guided optimization of a lead compound, identified through high-throughput screening, gave rise to sub-nanomolar inhibitors of human sEH with stability in human liver microsomal assay suitable for preclinical development. © 2012 Elsevier Ltd. All rights reserved.

Emu Today, January 15, 2013, Eastern Michigan University

EMU Today

No abstract provided.

Metallization Of Dna And Dna Origami Using A Pd Seeding Method, Yanli Geng

Theses and Dissertations

In this dissertation, I developed a Pd seeding method in association with electroless plating, to successfully metallize both lambda DNA and DNA origami templates on different surfaces. On mica surfaces, this method offered a fast, simple process, and the ability to obtain a relatively high yield of metallized DNA nanostructures. When using lambda DNA as the templates, I studied the effect of Pd(II) activation time on the seed height and density, and an optimal activation time between 10 and 30 min was obtained. Based on the Pd seeds formed on DNA, as well as a Pd electroless plating solution, continuous …

The George-Anne, Georgia Southern University

The George-Anne

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Scaffold For Bone And Tissue Repair In Mammals, D. E. Day, Steven B. Jung

Materials Science and Engineering Faculty Research & Creative Works

A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.

Using Remote Sensing And Gis To Assess The Effects Of Land Use/Cover Change And Geographic Variables On The Spread Of Poisonous Invasive Giant Hogweed In Latvia, Simon Foteck Fonji

Electronic Theses and Dissertations Archive

Land-use land-cover change (LULCC) especially those caused by human activities, is one of the most important components of global environmental change (Jessen, 2005). This dissertation analyses the effects of geographic, biographical, and demographic factors on LULCC and how LULCC and geographic variables influence the spread of invasive Giant Hogweed in northeastern Latvia. Data sets used in this study include: remote sensing images (Landsat Thematic Mapper acquired in 1992 and 2007), global positioning system (GPS data), census data, and data from public participation geographic information systems (PPGIS). These data were processed and analysed in a geographic information system (GIS). Six categories …

Ariana: Adaptive Robust And Integrative Analysis For Finding Novel Associations, Vida Abedi

Electronic Theses and Dissertations Archive

The effective mining of biological literature can provide a range of services such as hypothesis-generation, semantic-sensitive information retrieval, and knowledge discovery, which can be important to understand the confluence of different diseases, genes, and risk factors. Furthermore, integration of different tools at specific levels could be valuable. The main focus of the dissertation is developing and integrating tools in finding network of semantically related entities. The key contribution is the design and implementation of an Adaptive Robust and Integrative Analysis for finding Novel Associations. ARIANA is a software architecture and a web-based system for efficient and scalable knowledge discovery. It …

The Current Volume 23 : Issue 16, Nova Southeastern University

Student Newspapers

No abstract provided.

Risk And Manifestation Of Cardiovascular Disease Among Cancer Caregivers: Effects Of Stress, Depression, And Gender, Kelly M. Shaffer

Open Access Theses

Family members and friends who provide unpaid care to an ill relative tend to experience higher levels of stress, more depressive symptoms, and greater vulnerability to disease than the general population (Pinquart & Sörensen, 2003). This study was to determine whether cancer caregivers experience an increased risk of cardiovascular diseases (CVD) and to examine the extent to which psychosocial variables related to the disease outcomes. A total of 896 caregivers participated in a national survey at two years after the diagnosis of their relative with cancer (T1), and 607 participated again at five years post-diagnosis (T2) provided self-report data on …

January 14, 2013, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Macalester Grants Tenure Status To Seven Faculty Members, Macalester College

College Press Releases

No abstract provided.

Flooring And Driving Conditions During Road Transport Influence The Behavioural Expression Of Cattle, Catherine A. Stockman, Teresa Collins, Anne L. Barnes, David Miller, Sarah L. Wickham, David T. Beatty, Dominique Blache, Françoise Wemelsfelder, Patricia A. Fleming

Sentience Collection

This study examined whether observers could distinguish between cattle that were exposed to various road transport conditions: Experiment 1 compared a manipulated flooring treatment (non-grip flooring, NG) with a control transport event (grip flooring, G) and Experiment 2 compared a manipulated driving style (stop-start driving, SS) with a control transport event of smooth, continuous (C) driving. The behavioural expression of cattle was assessed through the process of Qualitative Behavioural Assessment (QBA), and these assessments were tested for correlation with various physiological parameters. Fourteen Angus steers were assessed. Blood samples were collected immediately before and after transport, and heart rate and …

Effect Of Implementing Best Management Practices On Water And Habitat Quality In The Upper Strawberry River Watershed, Fulton County, Arkansas, Usa, Teresa R. Brueggen-Boman

Student Theses and Dissertations

A study was conducted, May 2008-August 2012, to determine the impact of BMPs on streams located in the upper subwatersheds of the Strawberry River, Arkansas (AR). Multiple BMPs, including fencing, alternative drinking sources, planting of native grasses and brush, nutrient and pest management, were implemented in a whole watershed approach in attempts to alleviate the impacts of cattle grazing on surrounding waterways. Six locations were monitored for chemical, bacteriological, biological and physical responses to BMPs. Water quality variables used to assess the effectiveness of implemented BMPs included pH, turbidity, total suspended solids (TSS), NO2-, NO3-, PO43-, Escherichia coli and Chlorophyll-a. …

01-14-2013 Biology Seminar This Wednesday Focuses On Bees, Southwestern Oklahoma State University

THE BARK ARCHIVE 2013

The Southwestern Oklahoma State University Department of Biological Sciences’ Seminar Series will open the spring semester with a presentation from Dr. Victor Gonzalez this Wednesday, January 16, at 4 p.m. in Room 212 of the Old Science Building.

01-14-2013 Rodriguez Receives Aauw Scholarship, Southwestern Oklahoma State University

THE BARK ARCHIVE 2013

Southwestern Oklahoma State University student Ashley Rodriguez of Clinton has been named the recipient of a $300 Nancy McClain Honorary Scholarship from the American Association of University Women (AAUW) chapter in Weatherford.

The Pan American (2013-01-14), Karen Antonacci, Daniella Diaz

UTPA Archives - The Pan American Newspaper

Vol. 69, No. 14

The Collegian (2013-01-14), Joe Molina

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 65, No. 15

Emu Today, January 14, 2013, Eastern Michigan University

EMU Today

No abstract provided.

Daily Eastern News: January 14, 2013, Eastern Illinois University

January

No abstract provided.

The Bg News January 14, 2013, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 14, 2013. Volume 92-Issue 54.