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Exploring The Role Of Cesa5 In The Synthesis Of Cellulose Using Physcomitrella Patens, Oumie Ceesay

Senior Honors Projects

Cellulose is very essential to plants because it determines the shape of cells, protects them from pathogens, and helps retain water that is needed for plant functions. It is also the major component of wood, cotton, and paper, which are items we use on a daily basis. Also, it can be used for the synthesis of biofuels. However, cellulose exists as strong fibers, which make it hard to breakdown for biofuel synthesis. If we can understand how cellulose is synthesized we can manipulate its fibers to make them stronger, more flexible, more absorbent, or easier to break down for use …

The Effects Of Refuge On Escape Responses Of Two Caribbean Goby Species, Russell P. Dauksis

Senior Honors Projects

The Effects of Refuge Abundance on Escape Responses of the Bridled Goby (Coryphopterus glaucofraenum)

Russell P. Dauksis

Major

Marine Biology

Advisor

Dr. Graham Forrester

Advisor Department

Natural Resources Science

Date

5-2012

Keywords

Escapology, marine ecology, functional morphology, animal behavior, predator-prey interactions, Bridled Goby, Coryphopterus glaucofraenum

Abstract

Interactions between predators and prey species are arguably the most pervasive and important events in ecology. Predators have strong effects on the distribution and abundance of prey in virtually all environments. In the long-term, it is therefore hardly surprising that selective mortality imposed by predators has shaped a wide array of prey behaviors …

The Utility Of Planning And Other Spatial Concepts In The Marine Spatial Management Of Marine Protected Areas (Mpas), Marine Reserves, Marine Zoning, Marine Sanctuaries And Parks, Marine Spatial Planning (Msp), Large Marine Ecosystems (Lmes) And Seascape / Marine Design., Samuel Martin, Brandyn Lucca, Dr. William R. Gordon Jr.

Senior Honors Projects

In the last fifty years, man has demonstrated an increased interest in gaining access to and apportioning the near and offshore marine environment. Governments, coastal and marine managers, economic-based users, stakeholders, and academics have gained an interest and involvement in the demarcation of marine boundaries. Many land-based spatial applications, utilized from disciplines such as planning, geography, landscape architecture and regional science have been applied to the spatial acquisition and management of ocean resources. In the last four decades new marine applications have emerged, they include: 1) Marine Protected Areas (MPAs), 2) Marine Reserves, 3) Marine Zoning, 4) Marine Sanctuaries, and …

Fumihiko Maki And His Theory Of Collective Form: A Study On Its Practical And Pedagogical Implications, Xi Qiu

All Theses and Dissertations (ETDs)

This thesis seeks to reexamine Fumihiko Maki’s Investigations in Collective Form: 1964) from a historical and educational point of view, speculating the practical and pedagogical implications of Maki’s collective form theory. Firstly, to better understand the formation of both the writer himself and the book, the historical context in the 1950s and 1960s will be unfolded to reveal what Maki had encountered during his formative years that had contributed to his cross-cultural background and had inspired his thoughts in the book. Secondly, the three paradigms and the notion of linkage, as proposed in the book, will be analyzed through comparisons …

Identification Of Genetic Determinants Of Metastasis And Clonal Relationships Between Primary And Metastatic Tumors, Gaurav Singhal

All Theses and Dissertations (ETDs)

No abstract provided.

Competition In A Simple Pond: A 3d Agent Based Model Approach., Emil W.H. Montano

Undergraduate Honors Theses

If two species are competing for a limited resource, the species that uses the resource more efficiently will eventually eliminate the other. This is known as the principle of competitive exclusion developed by Georgy Gause. To determine the effect of this competition, a simple three-dimensional model of a pond is created in which two species compete for a single source of energy (algae). The model is based solely on the conservation of the energy that flows through an ecosystem where primary production is the only source of energy. The first scenario tested is of two competing species with identical life …

The Study Of The Effect Of Two Flavone Isomers Derived From Gnaphalium Elegans And Achyrocline Bogotensis In Breast Cancer., Jessica J. Walker

Undergraduate Honors Theses

Flavonoids are ubiquitous to all terrestrial plants and many are known to have anti-tumor activities. In this research project we studied the differential cytotoxic effects of two flavone isomers on human breast cancer cells (BT-474, SKBR-3, and MCF-7) and normal breast cells as a control (MCF-10A). The basis of the relationships between chemical structures, type and position of substituent groups and the effects these compounds exert specifically on cancer cells are not completely elucidated. These flavones are derived from plants native of Colombia, South America. These plants of the family Asteraceae, genera Gnaphalium and Achyrocline are reputed to have anti-cancer …

Recombination And Screening Of Putative Grapefruit Glucosyltransferase 4 Expressed In Pichia Pastoris., Peri Loftis

Undergraduate Honors Theses

Flavonoids are a group of plant secondary metabolites that are vital to the cell systems of plants. The intake of these chemicals is advantageous to animals for their antioxidant properties that affect the function of immune and inflammatory cells. The bitter taste of grapefruit (Citrus paradisi) and other citrus species is caused by the accumulation of glycosylated flavonoids. Glucosyltransferases (GTs) are enzymes that add glucose moieties to a carbon or hydroxyl group of natural products. The function of a putative secondary product GT clone was tested. In previous research, putative GT 4 was cloned into a pCD1 modified …

Spirit In The Speakers: Collective Spirituality In Electronic Music Subcultures., Heather K. Covington

Undergraduate Honors Theses

By definition subcultures harbor their own sets of norms and unique characteristics. From fashion to slang vocabularies, each subculture stands apart as a world of its own. In the subculture of psychedelic trance, an electronic music based subculture, such marking characteristics are taken beyond superficial expressions. Through repeated exposure to spiritual concepts, language, and rituals, thecommunity fosters spiritual practices and beliefs in individual members. Using in-depth interviews and extended participant observation, Iidentify patterns and commonalities, as well as divergences, in the spiritual practice and beliefs of subculture members. Ultimately psy-trance members draw on organized religious traditions while also distinguishing their …

Putative Glucosyltransferase 11 From Citrus Paradisi: Cloning, Recombinant Expression In Yeast, And Substrate Screening., Bruce E. Williams

Undergraduate Honors Theses

Plant secondary products, which include the flavonoids, have a variety of roles in plant systems. Their roles include UV protection, antifeedant activity, pollinator attraction, stress response, and many others. Flavonoids also have effects on human physiology. Glucosylation is an important modification of many flavonoids and other plant secondary products. In grapefruit, glucosylation is important in the synthesis of the bitter compound naringin. Glucosyltransferases catalyze glucosylation reactions. Putative plant secondary product glucosyltransferases may be identified by the loosely conserved “PSPG box” amino acid sequence, and eleven have been isolated to date in Citrus paradisi. With current knowledge, however, biochemical characterization …

It's Not So Simple: The Role Of Simplicity In Science And Theory., C. R. Gregg

Undergraduate Honors Theses

The principle of simplicity (parsimony) has long been invoked as a regulative principle that helps guide theory selection in science. However, it is unclear if there is justification for a globally applicable criterion of parsimony. This paper briefly reviews the salient features of what it means for something to be simple, as well as argues for simplicity as relevant only to a set of background assumptions.

Finding Meaning In The Two-Finger Banjo Style., Jeffrey K. Elkins

Undergraduate Honors Theses

The two-finger banjo style languishes as a small footnote in the lexicon of old time banjo music—very important to a passionate (and lucky!) few, but not known by too many others. This research is a starting point to understanding the meaning of two-finger banjo; through a review of primary literature, interviews, witnessing performances, and individual investigation of playing two-finger banjo, I have been able to document some understandings about the style.

These understandings informed further appreciation of old time music, the old time music (and banjo) communities, and the art of making music in this way—while describing the journey, I …

Chiral Analyses Of Ephedrines, Lyanne Valdez

Honors College Theses

Chiral molecules rotate plane-polarized light and have two or more forms known as enantiomers. We plan to separate the two enantiomeric ephedrines using β-cyclodextrin column in gas chromatography-mass spectrometry (GC-MS).To achieve this, a series of methods were developed through the modification of temperature and mobile phase parameters.

An Intersectional Comparison Of Female Agency In Toni Morrison's Sula And Wang Anyi's Song Of Everlasting Sorrow, Jordan Lynton

HIM 1990-2015

The opportunities created by the end of the Mao Era and legislature promoting the rights of African Americans and women in the mid-twentieth century allowed women of both cultures to break further into the literary scene and negotiate their own sense of agency through their work. Although Western feminism also grew rapidly throughout this period, its ethnocentric centering of gender prevented it from being a reliable lens with which to analyze the work of Chinese and African American women who experienced issues of race, class, and gender simultaneously. This caused Western feminists to evaluate the work of Chinese and African …

Water Governance In The Postcolonial Developing World, Alaina Mallette

Renée Crown University Honors Thesis Projects - All

Water is an essential part of life. However, the right to govern water as a resource is not shared equally by all members of our global community. Every location around the world has had a unique historical, political, and cultural relationship with water. Countries need to tailor their water regimes to the unique lived experiences of all their citizens, if they are to meet the right of all humans to affordable and accessible water. Governance structures must be transparent, inclusive, and holistic. This paper analyzes literature on international water governance, and addresses a local case of water governance in Cabarete, …

A Novel Therapeutic Approach In Breast And Hematopoietic Cancers: Inhibition Of Sh2-Domain Containing Inositol 5' Phosphatase (Ship), Amamda Balch

Renée Crown University Honors Thesis Projects - All

Aberrant hyperactivation of the phosphatidylinositol 3-kinase (PI3K) cell-signaling pathway, one of the most prominent cell growth, proliferation and survival pathways in the human body, has been observed in many forms of cancer. Upon deregulation, this pathway can facilitate the evasion of programmed cell death, the stimulation of autonomous growth, and the evasion of regular growth-inhibitory signals. While it was initially believed that the dephosphorylation activity of lipid phosphatases served to counteract the pathway by hydrolyzing phosphatidylinositol(3,4,5)trisphosphate (PtdIns(3,4,5)P₃) to phosphatidylinositol(4,5)bisphosphate (PtdIns(4,5)P₂), emerging evidence suggests that SH2-domain containing inositol 5’ phosphatase 1 and 2 (SHIP1/2) may in fact …

Seeing Adoption With Eyes Wide Open, Cheryl Millman

Instructional Design Capstones Collection

Families who choose to adopt may do so for a variety of reasons. Some may choose to adopt due to infertility or medical issues with one or both of the parents, so they may choose to adopt to avoid the risk of passing on a genetic or medical condition. Some may believe they are saving a child who otherwise would not grow up with the benefits of a loving and supportive family, and some choose to adopt because they lack an appropriate partner with whom to have a biological child. Regardless of the reason, parents believe that with love and …

Barriers And Facilitators To The Effective Management Of Gestational Diabetes Mellitus For Hispanic Women, Paula F. Clark

Master's Theses

Gestational diabetes mellitus (GDM) is an abnormal or unfavorable condition in pregnancy, as well as a life event, that puts a woman and her biological children at an elevated risk for developing a number of negative fetal, neonatal, and maternal outcomes, including the future development type 2 diabetes in both mother and baby. These complications are associated with elevated maternal blood glucose. Diet and exercise alone are often sufficient to control blood glucose and effectively avoid negative outcomes. Yet research has determined that barely 50% of women with gestational diabetes are able to adhere to prudent dietary and exercise GDM …

Atomic And Electronic Structure Of A Ligand-Protected Bimetallic Nanocluster, Ag4ni2(Dmsa)4, Anthony F. Pedicini

Theses and Dissertations

An important direction in nanoscale science is to synthesize materials whereby atomic clusters serve as the building blocks. Properties of these clusters can be controlled through size and composition, and such an approach offers a pathway toward designing larger, customized materials. One way to stabilize such materials is through the use of ligated clusters. Ag4Ni2(DMSA)4 is one such cluster, the first with a bimetallic core, and has been stabilized by the experimental group of A. Sen at The Pennsylvania State University. The theoretical studies undertaken in this thesis were directed toward providing information on the atomic structure, nature of electronic …

Primary Productivity Distributions Along The River-Dominated Shoreline Of The Bay Of St. Louis, Ms Estuary, Adam Douglas Boyette

Master's Theses

Potential primary production was measured for six consecutive months (July 2010 to December 201 0) at selected stations along the shoreline of the Bay of Saint Louis (BSL) estuary. Monthly surface and a series of subsurface (0.5 m) samples were taken to observe the temporal (monthly and short-term) and spatial variability in production relative to environmental variables that potentially could influence phytoplankton photosynthesis. Daily areal primary production, PP was modeled using photosynthesis-irradiance (P-E) parameters in conjunction with in situ irradiance measurements and biomass data collected during sampling. Although spatial variability was not observed, PP varied seasonally and ranged from 1.90 …

The Identification Of The Mid Transcription Factor Regulatory Network Specifying Cell Fate And Regulating Survival In The Drosophila Eye, Sudeshna Das

Master's Theses

The Drosophila melanogaster T-box transcription factor Midline (Mid) exhibits a high degree of structural and functional conservation with its vertebrate homolog Tbx-20. Both Mid and Tbx-20 regulate cell-fate specification with in diverse tissues including the central nervous system (CNS) and heart. Although, some important studies reported that Tbx-20 transcripts express in a wide range of developing mammalian eye tissues including those of the human fetus, the function of this transcription factor is unknown in the development of eye tissue. This current study is the first attempt to show that Mid and its para log H15 are expressed within distinct ommatidial …

The Effects Of Angiogenic Growth Factors On Mesenchymal Stem Cell Proliferation And Differentiation To Vascular Cell Fates, William Anthony D'Angelo

Master's Theses

Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into several cell lineages, including mural cells, which surround and support blood vessels, and possibly endothelial cells, which form the blood vessel walls. In this study, we investigated the effects of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF), two of the best-characterized angiogenic factors, on MSC proliferation and differentiation. We hypothesized that treatment with these two factors could inhibit mural cell character and promote differentiation toward an endothelial cell fate. C3H/10T1/2 cells (a line of MSCs derived from mouse embryonic tissues) were treated with bFGF and …

Conservation Genetics Of Threatened Gopher Tortoises, Gopherus Polyphemus: An Assessment Of Genetic Variation And Parentage In Two Populations In South Mississippi, Angela Huang Getz

Master's Theses

Despite the protection of gopher tortoises, Gopherus polyphemus, in the western portion of their range for over twenty years, populations of the De Soto National Forest (DNF) in southern Mississippi experience low recruitment and lower hatching success than populations in the eastern portion of the range, and the causes of this are unknown. Previous work has shown that Mississippi populations of the DNF have lower levels of genetic diversity than eastern populations, which prompted the suggestion that reduced levels of genetic variation may play a part in low hatching success. Small populations can become more susceptible to the effects …

Recent Characterizations Of Mscs And Its Homologs Provide Insight Into The Basis Of Ion Selectivity In Mechanosensitive Channels, Grigory Maksaev, Elizabeth S. Haswell

Biology Faculty Research

The bacterial mechanosensitive channel MscS provides an excellent model system for the study of mechanosensitivity and for investigations into the cellular response to hypoosmotic shock. Numerous studies have elucidated the structure, function and gating mechanism of Escherichia coli MscS, providing a wealth of information for the comparative analysis of MscS family members in bacteria, archaea, fungi and plants. We recently reported the electrophysiological characterization of MscS-Like (MSL)10, a MscS homolog from the model flowering plant Arabidopsis thaliana. Here we summarize our results and briefly compare MSL10 to previously described members of the MscS family. Finally, we comment on how …

Interactions Between Protozoan Prey (Phylum Protista) And Their Mosquito Predators (Order Diptera, Family Cuclicidae) Prey Size And Predator Behavior Effects, Jeffrey Jay Skiff

Master's Theses

Mosquitoes (Diptera. Culicidae) are insects that are medically important as adults as they vector numerous diseases. Yet, understanding the ecology of the larval stage can lead to surveillance and control of adult populations. Aedes albopictus, Aedes triseriatus, Cu/ex corona/or, and Culex quinquefasciatus are four species of mosquito that co-occur in discarded automobile tires. Mosqui-to larvae feed on microorganisms (including protozoans) and particulate organic matter Most larval feeding experiments. howt:ver, have dealt exclusively with bacteria, fungi , and particulate organic matter Although bactena and fungi are important sources of nitrogen and lipids, they may be 111sufficient sources of carbon, which may …

The R2p Is Dead. Long Live The R2p. Libya, Syria, And The Responsibility To Protect, Nadir Edul Dalal

Student Works

No abstract provided.

Generation Of A Transgenic Zebrafish (Danio Rerio) Expressing The Transcriptional Repressor Inducible Camp Early Repressor (Icer), Theodora Tsatsos

Theses, Dissertations and Culminating Projects

Inducible cAMP early repressor (ICER) has been known to moderate cAMP antiproliferative actions. It has ovarian- specific properties and its gene product has been shown to act as a tumor suppressor. It has been previously shown that ICER has been targeted for expression in the ovaries via a transgenic mouse model to create an increased level of ovulation. In this paper, we cloned the following ovarian-specific promoters: CYP19A1, FSH, ZP3, and GDF9. Plasmid DNA was constructed with the aforementioned ovarian specific promoters using a three-fragment vector construction method and EGFP was used as a marker to follow whether plasmid DNA …

Compound Identification Using Penalized Linear Regression., Ruiqi Liu

Electronic Theses and Dissertations

In this study, we propose a new method for compound identification using penalized linear regression. Compound identification is often achieved by matching the experimental mass spectra to the mass spectra stored in a reference library based on mass spectral similarity. In the context of the linear regression, the response variable is an experimental mass spectrum (i.e., query) and all the compounds in the reference library are the independent variables. However, the number of compounds in the reference library is much larger than the range of m/z values so that the data become high dimensional data with suffering from singularity. For …

Genetic Characterization Of The K2 Serotype Capsule Of Klebsiella Pneumoniae Atcc 43816 And The Development Of A Bioluminescent Strain., Jacob Brandon Scott 1987-

Electronic Theses and Dissertations

OBJECTIVE: Klebsiella pneumoniae is a Gram-negative enterobacterium that is a major cause of community-acquired and nosocomial infections. We performed a genetic characterization of K. pneumoniae strain ATCC 43816, which is a well-studied strain with a K2 serotype capsular polysaccharide. To provide the ability to monitor bacteria within a host, we will develop a bioluminescence strain of K. pneumoniae by integrating the lux operon into the chromosome. METHODS: The ATCC 43816 capsule cluster sequencing was performed by closing gapE, in the Next Generation Sequencing by long range peR for template and primer walking. We constructed a bioluminescent K. pneumoniae by using …

Improving Cervical Cancer Nodal Boost Radiation Therapy By Quantifying Uncertainties And Exploring Advanced Radiation Therapy Modalities, Zhiqian Yu

Dissertations and Theses (Open Access)

Radiation therapy for patients with intact cervical cancer is frequently delivered using primary external beam radiation therapy (EBRT) followed by two fractions of intracavitary brachytherapy (ICBT). Although the tumor is the primary radiation target, controlling microscopic disease in the lymph nodes is just as critical to patient treatment outcome. In patients where gross lymphadenopathy is discovered, an extra EBRT boost course is delivered between the two ICBT fractions. Since the nodal boost is an addendum to primary EBRT and ICBT, the prescription and delivery must be performed considering previously delivered dose. This project aims to address the major issues of …