Digital Commons Network^™

Defining A Role For Inducible Heat Shock Protein 70 (Hsp70i) In Mediating Autoimmune Vitiligo, Jeffrey Alan Mosenson

Dissertations

Vitiligo is an autoimmune disease characterized by destruction of melanocytes, leaving 0.5% of the population with progressive depigmentation. Current treatments offer limited efficacy. Observations that heat shock proteins (HSPs) can serve as adjuvants in antitumor vaccines first suggested to us a link between HSPs and stress-induced vitiligo. Such proteins are marvelously well conserved throughout evolution, which has placed them in the spotlight for helping to understand the intriguing relationship between infection and immunity. Intracellularly, inducible heat shock protein 70 (HSP70i) is upregulated by stress and helps protect cells from undergoing apoptosis. In times of stress, melanocytes will secrete antigen bound …

The Religion Of Consumption And Christian Neighbor Love, Christopher Porter

Dissertations

Loyola University Chicago

THE RELIGION OF CONSUMPTION AND CHRISTIAN NEIGHBOR LOVE

Consumerism is a word frequently used in various disciplines to express the variety of attitudes, motivations, and practices found among the middle and upper classes. It drives the global economy and influences individuals' socio-psychological perceptions. Some have gone so far as to call consumerism a religion, yet they have not substantiated this claim. This dissertation offers a framework that accounts for consumerism as a religion both as a person's ultimate concern and as a structuralized belief system. As such, it prescribes moral values that shape how people respond to …

Religious Pluralism And The Catholic Church: Lonergan's Method And The Jacques Dupuis Controversy, Andrea J. Stapleton Berger

Dissertations

This project applies Lonergan's method to the controversy that resulted from the censure of Jacques Dupuis by the Congregation for the Doctrine of the Faith over his book, Toward a Christian Theology of Religious Pluralism. The application of Lonergan's method reveals the potential for the resolution of the issues presented by Dupuis in the area of developing a Catholic theology of pluralism as well as the tension between the Catholic Magisterium and the work of Catholic theologians.

Brown V. Entertainment Merchants Association: "Modern Warfare" On First Amendment Protection Of Violent Video Games, Jessica Fisher

Journal of Business & Technology Law

No abstract provided.

Evaluation Findings From Santa Cruz County’S “Roots & Wings” Initiative, Kathy Lemon Osterling, Amy D'Andrade

Faculty Publications

This report provides new findings on three outcome areas within the Roots and Wings Initiative: 1) systems change to promote concurrent planning and permanency (Staff Permanency Survey results), 2) recruitment and licensing outcomes, 3) Resource home questionnaire results, and 4) long-term outcomes related to permanency, placement stability and sibling placements. Overall, there are a number of indicators that are changing in the intended direction, suggesting that Roots and Wings activities are influencing key outcomes.

Are Rural People More Anti-Immigrant Than Urban People? A Comparison Of Attitudes Toward Immigration In The U.S., Carlos E. Garcia, T. Davidson

Faculty Publications, Sociology

Immigration to the United States has increased markedly in the past two decades, including significant growth in rural areas. Using General Social Survey data we compare rural and urban attitudes toward immigration in the United States. Our analyses reveal that, first, overall opposition is more pronounced in rural areas. Second, notions of a distinct American identity matter for urban, but not rural, residents. Third, beliefs about immigration are salient predictors in both regions. Fourth, political ideology is a determinant exclusively among rural residents, whereas political affiliation is a determinant solely among urban residents. Fifth, race and education level are significant …

2012-2013 Annual Report, Society Of American Archivists Student Chapter

Annual Reports

No abstract provided.

Book Review: Placing The Suspect Behind The Keyboard: Using Digital Forensics And Investigative Techniques To Identify Cybercrime Suspects, Thomas Nash

Journal of Digital Forensics, Security and Law

In this must read for any aspiring novice cybercrime investigator as well as the seasoned professional computer guru alike, Brett Shaver takes the reader into the ever changing and dynamic world of Cybercrime investigation. Shaver, an experienced criminal investigator, lays out the details and intricacies of a computer related crime investigation in a clear and concise manner in his new easy to read publication, Placing the Suspect behind the Keyboard. Using Digital Forensics and Investigative techniques to Identify Cybercrime Suspects. Shaver takes the reader from start to finish through each step of the investigative process in well organized …

Book Review: Iphone And Ios Forensic: Investigation, Analysis And Mobile Security For Apple Iphone, Ipad And Ios Devices, Simson Garfinkel

Journal of Digital Forensics, Security and Law

In April 2011 news outlets around the world revealed shocking news about Apple’s iPhone: for reasons that were not apparently clear, every iPhone contained a small SQLite database that logged where and when the user had been whenever the phone was turned on, and those records went back for pretty much as long as the user had owned their phone. Apple eventually declared that the data cache was the result of a bug and issued a software update to prune the database (it had previously grown without limit). Privacy activists rejoiced that their beloved iPhones were once again trustworthy. But …

Factors That Impact Pseudo-Nitzschia Spp. Occurrence, Growth, And Toxin Production, Naomi Downes-Tettmar

School of Geography, Earth and Environmental Sciences Theses

This work investigates, for the first time, the Pseudo-nitzschia (PN) dynamics in the western English Channel (L4) and the environmental factors impacting on domoic acid (DA) production in these waters. This is combined with laboratory studies examining key environmental factors and the multifactorial impact of multiple macronutrient and micronutrient availability on PN growth and DA production. An LC-MS method was established, optimised, and compared with ELISA for the accurate and reproducible extraction and determination of particulate and dissolved DA. The method was used to measure the seasonal variation in DA at L4 during 2009 and this was compared to PN …

Allotments And Alternative Food Networks: The Case Of Plymouth, Uk, Wendy M Miller

School of Geography, Earth and Environmental Sciences Theses

Alternative food networks (AFNs) are the focus of an ‘explosive growth’ of research in Europe (Goodman 2004), and the term covers a wide range of activities, from food banks, community gardens, and farmers’ markets, to community supported or organic agriculture. However, there is an impasse in differing positions over whether AFNs represent an exclusionary place-based ‘quality turn’ (Ilbery and Kneafsey 2000), or whether they contribute to inclusive local communities, sustainability and food security (Tregear 2011, Kirwan and Maye 2013). This research aimed to clarify these debates, through exploration of UK allotments as a benchmark for AFNs, using the case of …

Suicide In Adults Aged 75 And Over In Cornwall: An Epidemiological And Case Study Analysis, Sarah Buckingham

School of Nursing and Midwifery Theses

Introduction/Background: Suicide in older people is a historically neglected research area. Local audits had suggested that Cornwall had a higher than average suicide rate, and people aged 75 years and over appeared to be at particularly high risk. Heterogeneity between studies and variations in presenting suicide statistics can make comparison of rates difficult. Aims: The study aimed to explore in depth the epidemiology of suicide in elderly people in Cornwall, to develop an understanding of the risk factors (including sources of stress), suicide methods, locations, and warnings, and consequently to identify potential preventive strategies. Methods: A mixed methods approach was …

Redefining Murder: Joint Enterprise, Nicola Mitchell-Rod

The Plymouth Law and Criminal Justice Review

This article explores the evolution of secondary liability and the unforgiving doctrine of joint enterprise in homicide cases. Exploration of the current law ensues to determine if the distinct decisions of their Lordships in both Powell and Rahman have failed to sufficiently clarify the law; followed by in depth analysis of the Law Commission and Ministry of Justice proposals to reform this infamously disputed area of law.

Why Is There Lack Of Recognition For British Children Who Are Victim To Internal Trafficking For Sexual Exploitation?, Anne Westcott

The Plymouth Law and Criminal Justice Review

Child trafficking has been conceptualised as 'modern day slavery'. Slavery has been held up as the worst possible exploitation in human history (Lee, 2007). For more than 20 years UK governments have ratified United Nation Conventions and Protocols and rescheduled laws in its effort to eradicate this crime. However, despite such political commitment, in reality thousands of British children are still victims to internal trafficking for sexual exploitation in the UK today. Over the last 10 years the UK government has employed agencies, in the shape of the UK Human Trafficking Centre (UKHTC), the National Referral Mechanism (NRM) and the …

The Uncertainty Of Article 8 Echr In Relation To The Removal Of Foreign Criminals, Lucy Nash

The Plymouth Law and Criminal Justice Review

This article highlights concerns regarding judicial interpretations and understandings of the application of Article 8 European Convention on Human Rights to control the deportation of foreign criminals from the United Kingdom. It examines the broad scope of the provision arguing that it is somewhat unclear, vague and unpredictable for those seeking to rely on it.

The Recognition Of State Crime And The Syrian Uprising, Nicholas Smith

The Plymouth Law and Criminal Justice Review

This study aims to establish why state crime is not always recognised as such. The criminological analysis of state crime is a fledgling field of interest, although over the past decade there have been significant developments. As a result of these recent developments it is possible to theoretically interact with state crime. Through theoretical engagement, within a real life context, the phenomenon of recognition of state crime is explored. A case study of the recognition of state crime during the first 15 months of the Syrian uprising provides the real life context. An 'adaptive theory' approach is adopted promoting the …

Reflections On Restorative Justice Conference - 'Creating A More Transparent, Responsive And Effective Criminal Justice System', Gareth Addidle

The Plymouth Law and Criminal Justice Review

No abstract provided.

Pregnant And In Prison: Can The Quality Of Services Provided Affect The Overall Perception Of Being Pregnant In Prison?, Peter Chatten

The Plymouth Law and Criminal Justice Review

The suicides of six women within a year at Styal Prison in 2006 (Prison Reform Trust: 2010) lead the Government to appoint Baroness Jean Corston to undertake a review of women with particular vulnerabilities in the criminal justice system. The result? The Corston Report, a document with recommendations for a new woman-centred approach in dealing with female offending. Whilst this was a progressive movement, one particular minority of prisoners received little mention – pregnant women. With no official statistics on the number of pregnant women in prison, they become a difficult group to provide services for even though they are …

Foundations In Wisconsin: A Directory [32nd Ed. 2013], Mary C. Frenn, Katie M. Barnhart, Victoria Browne, Anne M. Carpenter, Melanie Pauly, Jakob K. Rinderknecht

Foundations in Wisconsin: A Directory

The 2013 edition of Foundations in Wisconsin marks the 32nd production of the print directory and the 13th year of the online version. The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was drawn from IRS 990-PF tax returns filed by the foundations. Additional information was obtained from surveys, foundation websites, annual reports, and newsletters.

A Critical Evaluation Of Community Rail Policy And Practice During The New Labour Years 2003 - 2010, Andrew Seedhouse

School of Geography, Earth and Environmental Sciences Theses

Seedhouse, Andrew Colin A Critical Evaluation Of Community Rail Policy And Practice During The New Labour Years 2003 - 2010 This thesis examines how the changing governance environments introduced under New Labour compromised or assisted the delivery of the 2004 Community Rail Development Strategy. It considers the origins of Community Rail and the circumstances which led to the adoption of the 2004 Strategy and its content. It explores the wider processes of governance change across multiple scales and the rise of a new neoliberal approach favoured by recent administrations, with particular emphasis of New Labour’s introduction of the Third Way …

Effectiveness Of Moving On: An Australian Designed Generic Self-Management Program For People With A Chronic Illness, A Williams, L Bloomfield, E Milthorpe, D Aspinall, K Filocamo, T Wellsmore, N Manolios, U Jayasinghe, M Harris

Nursing Papers and Journal Articles

Background: This paper presents the evaluation of “Moving On”, a generic self-management program for people with a chronic illness developed by Arthritis NSW. The program aims to help participants identify their need for behavior change and acquire the knowledge and skills to implement changes that promote their health and quality of life.

Method: A prospective pragmatic randomised controlled trial involving two group programs in community settings: the intervention program (Moving On) and a control program (light physical activity). Participants were recruited by primary health care providers across the north-west region of metropolitan Sydney, Australia between June 2009 and October 2010. …

Maryland's Family Divisions: Sensible Justice For Families And Children, Barbara A. Babb

All Faculty Scholarship

In January 1998, the judges of the Court of Appeals of Maryland signed Rule 16-204 and formally launched the process of family justice system reform in Maryland. During the ensuing fifteen years, Maryland became a national model in this area. These changes and improvements occurred largely because of the inspirational leadership of Chief Judge Robert M. Bell, a man owed a debt of gratitude by everyone involved in family law proceedings, including families, children, attorneys, judges, court personnel, and services providers, among others.

This Tribute honors Chief Judge Bell by contextualizing the enormity of the process and outcomes resulting from …

Einstein@Home Discovery Of 24 Pulsars In The Parkes Multi-Beam Pulsar Survey, Benjamin Knispel, Ralph P. Eatough, H. Kim, Evan F. Keane, Fronefield Crawford

Physics Faculty Scholarship

We have conducted a new search for radio pulsars in compact binary systems in the Parkes multi-beam pulsar survey (PMPS) data, employing novel methods to remove the Doppler modulation from binary motion. This has yielded unparalleled sensitivity to pulsars in compact binaries. The required computation time of 17, 000 CPU core years was provided by the distributed volunteer computing project Einstein@Home, which has a sustained computing power of about 1 PFlop s–1. We discovered 24 new pulsars in our search, 18 of which were isolated pulsars, and 6 were members of binary systems. Despite the wide filterbank channels and …

The Effects Of Oxygen And Reactive Oxygen Species On Antibiotic Resistance And Microbial Communities In Chronic Wounds, Lindsey Glew

Other Faculty of Science and Engineering Theses

Infection is one of the factors that may contribute to non-healing of chronic wounds; the presence of antibiotic resistant bacteria serves to exacerbate the problem due to limited treatment options. Bacteria utilise several mechanisms to survive exposure to antibiotics, including synthesis of deactivating enzymes, target modification or substitution, changes to membrane permeability, upregulation of efflux pumps and the formation of a biofilm. Quorum sensing is a density-dependent mechanism of bacterial cell to cell communication that can be instrumental in co-ordinating biofilm initiation. Hyperbaric oxygen therapy (HBOT) is an option offered to some patients with chronic wounds, including diabetic foot ulcers. …

An Investigation Of The Mechanism(S) Of Hyperoxia-Induced Cilial Epithelial Loss In Mammalian Bronchial Tissue, Hanady Abd Al-Sahib

Other Faculty of Science and Engineering Theses

Hyperoxia is an essential aid to life support in patients with severe respiratory failure. However, it is recognised as a contributor to the pathological consequences of oxidative stress including oxidative tissue damage, inflammation and cell death resulting in acute or chronic lung injury. The specific mechanisms behind this type of injury are still not completely understood. This study was undertaken with two main aims. Firstly, to evaluate the adverse effects of hyperoxia on the ciliary coverage using a novel large animal model. For the first time, an in vitro bronchus bovine tissue culture model was developed and used to quantify …

The Processing Of Accented Speech, Hester Elizabeth Sarah Duffy

Other Faculty of Science and Engineering Theses

This thesis examines the processing of accented speech in both infants and adults. Accents provide a natural and reasonably consistent form of inter-speaker variation in the speech signal, but it is not yet clear exactly what processes are used to normalise this form of variation, or when and how those processes develop. Two adult studies use ERP data to examine differences between the online processing of regional- and foreign-accented speech as compared to a baseline consisting of the listeners’ home accent. These studies demonstrate that the two types of accents recruit normalisation processes which are qualitatively, and not just quantitatively, …

Investigating The Role Of Counterfactual Thinking In The Excess Choice Effect, Rebecca Jayne Hafner

Other Faculty of Science and Engineering Theses

According to economic rational choice theory greater choice will deliver well-being by increasing the likelihood that individuals satisfy personal preferences (Mas-Colell, Whinston, & Green, 1995). Consequently, extensive choice has become a fundamental aspect of both consumer markets and public policy (Schwartz, 2000; 2004; Botti & Iyengar, 2006). Crucially however, recent psychological research has begun to challenge the assumption that more choice leads to greater well-being. In several instances evidence has been found that whilst some choice is good, more choice can lead to reduced post-decisional satisfaction (e.g. Iyengar & Lepper, 2000; Shar & Wolford, 2007; Reutskaja & Hogarth, 2009). This …

Interactions Between Porphyromonas Gingivalis And Macrophages In Oral Pathology, Louise A Belfield

Other Faculty of Science and Engineering Theses

Macrophages play a fundamental role in driving both inflammatory and immunosuppressive conditions of the oral mucosa. Periodontitis, a chronic inflammatory condition affecting the supporting structures of the teeth, is widely prevalent, affecting a large proportion of the global population, and has been linked to the development of systemic inflammatory diseases. Oral squamous cell carcinoma (OSCC) is placed sixth in the WHO rankings of cancer incidence worldwide, and despite continuing research into underlying mechanisms, incidence is on the rise. Aberrant macrophage function has been implicated in the pathogenesis of both diseases. On recruitment to sites of inflammation, macrophages become polarised within …

The Hybronaut And The Umwelt: Wearable Technology As Artistic Strategy, Laura Maria Beloff

Other Faculty of Arts, Humanities and Business Theses

This dissertation explores the use of irony in networked wearable technology art as a strategy to emphasise the complexity of conjunction between techno-organic human and the techno-organic world. The research addresses the relationship between technologically enhanced human and networked hybrid environment, and speculates on the impact of technological enhancements to the subjective construction of Umwelt through ironic interventions. The project employs both artistic practice and critical theory. The practice-based part of the dissertation is comprised of three wearable technology artworks produced during the study. These concrete artefacts employ irony as a means to expose the techno-organic relationship between humans and …

Toward A Female Clown Practice: Transgression, Archetype And Myth, Margaret J Irving

Other Faculty of Arts, Humanities and Business Theses

Women who learn to clown within Western contemporary theatre and performance training lack recognizably female exemplars of this popular art form. This practice-as-research thesis analyses my past and present clowning experiences in order to create an understanding of a woman-centered clown practice which allows for the expression of material bodies and lived experiences. It offers a feminist perspective on Jacques Lecoq’s pedagogy, which revolves around a notion of an ‘inner clown’ and is prevalent in contemporary UK clown training and practice. The thesis draws on both the avant-garde and numerous clown types and archetypes, in order to understand clowning as …