Digital Commons Network^™

Using Expression Profiling To Understand The Effects Of Chronic Cadmium Exposure On Mcf-7 Breast Cancer Cells, Zelmina Lubovac-Pilav, Daniel M. Borras, Esmeralda Ponce, Maggie Louie

Collected Faculty Scholarship

Cadmium is a metalloestrogen known to activate the estrogen receptor and promote breast cancer cell growth. Previous studies have implicated cadmium in the development of more malignant tumors; however the molecular mechanisms behind this cadmium-induced malignancy remain elusive. Using clonal cell lines derived from exposing breast cancer cells to cadmium for over 6 months (MCF-7-Cd4, -Cd6, -Cd7, -Cd8 and -Cd12), this study aims to identify gene expression signatures associated with chronic cadmium exposure. Our results demonstrate that prolonged cadmium exposure does not merely result in the deregulation of genes but actually leads to a distinctive expression profile. The genes deregulated …

Division Of California Into Six States. Initiative Statutory And Constitutional Amendment.

Initiatives

Divides California into six states subject to approval by Congress. Assigns each county to a new state, unless county voters approve reassignment to different new state and second state approves. Establishes commission to settle California's financial affairs after division; upon failure to resolve, each new state would retain assets within its boundaries and would receive proportionate distribution of California's debts based on population. Authorizes counties to refuse to provide State-mandated programs and services absent sufficient State reimbursement. Empowers counties to make and enforce all laws governing local affairs. Summary of estimate by Legislative Analyst and Director of Finance of fiscal …

Division Of California Into Six States. Initiative Statutory And Constitutional Amendment.

Initiatives

Divides California into six states subject to approval by Congress. Assigns each county to a new state, unless county voters approve reassignment to different new state and second state approves. Establishes commission to settle California's financial affairs after division; upon failure to resolve, each new state would retain assets within its boundaries and would receive proportionate distribution of California's debts based on population. Authorizes counties to refuse to provide State-mandated programs and services absent sufficient State reimbursement. Empowers counties to make and enforce all laws governing local affairs. Summary of estimate by Legislative Analyst and Director of Finance of fiscal …

The Murray Ledger And Times, December 20, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Chile’S Once And Future President Michelle Bachelet Wins Election Runoff In A Landslide, Benjamin Witte-Lebhar

NotiSur

No abstract provided.

Purifying The Human Rna-Lariat Debranching Enzyme, Ammar Saigal

Honors Program Theses and Research Projects

This project is my first official research endeavor and it involved becoming acquainted with a large variety of biochemistry and molecular biology techniques. The goal is to elucidate the structure of a protein common to most if not all cells of organisms within the Domain Eukarya, which is one of the three taxonomic domains into which all life is categorized. This is the domain most relevant to human beings as it includes plants, fungi, and animals (from a strictly biologically-taxonomic perspective, the species Homo sapiens to which you and I belong is considered belonging to the Kingdom Animalia [Animal]).

Rebuilding Post War Europe: New York And Digital Archives As Reconstitutive Fabric, Anthony Cocciolo

Urban Library Journal

This project explores four digital initiatives that document and make available to the public information related to American, German, and Jewish relationships before, during, and after World War II. The goal of these projects is to make primary source information available to the public using digital technology, in effect, creating an educational infrastructure for enhancing understanding among these groups. These four projects will be treated as cases, with the guiding question being: what infrastructures are needed to create a contemporary, educational, primary source-based digital platform? The goal of this study is to highlight those infrastructure elements that are instrumental in …

Grinding The Gears: Academic Librarians And Civic Responsibility, Lisa Sloniowski, Mita Williams, Patti Ryan

Urban Library Journal

Corporate encroachments are transforming universities into edu-factories which are designed to produce servants of the state rather than engaged citizens. Academic librarians have a duty to resist the machineries of the institution. This panel will survey the revolutionary potential inherent in the open source movement, feminist porn collections, and critical information literacy.

Genome Sequence Of The Clover-Nodulating Rhizobium Leguminosarum Bv. Trifolii Strain Ta1, Wayne Reeve, Rui Tian, Sofie E. De Meyer, Vanessa Melino, Jason Terpolilli, Julie Kaye Ardley, Ravi P. Tiwari, John Gregory Howieson, Ronald J. Yates, Graham William O'Hara, Mohamed Ninawi, Hazuki Teshima, David Bruce, Chris Detter, Roxanne Tapia, Cliff Han, Chia-Lin Wei, Marcel Huntemann, James Han, I-Min Chen, Konstantinos Mavromatis, Victor Markowitz, Natalia Ivanova, Galina Ovchinikova, Ioanna Pagani, Amrita Pati, Lynne Goodwin, Sam Pitluck, Tanja Woyke, Nikos Kyrpides

Grain and Other Field Crops Research Articles

Rhizobium leguminosarum bv. trifolii strain TA1 is an aerobic, motile, Gram-negative, non-spore-forming rod that is an effective nitrogen fixing microsymbiont on the perennial clovers originating from Europe and the Mediterranean basin. TA1 however is ineffective with many annual and perennial clovers originating from Africa and America. Here we describe the features of R. leguminosarum bv. trifolii strain TA1, together with genome sequence information and annotation. The 8,618,824 bp high-quality-draft genome is arranged in a 6 scaffold of 32 contigs, contains 8,493 protein-coding genes and 83 RNA-only encoding genes, and is one of 20 rhizobial genomes sequenced as part of the …

The Voices Of African American Women's Transition Experiences From A Community College To A Four-Year College Sharing A Campus, Lola Ames

Theses and Dissertations

African American women make up a substantial percentage of the higher education student population. Research on their participation is disproportionately underrepresented and in many cases embedded within the experiences of Euro-American women and African American men. This method of grouping has potentially led to their invisibility in research on higher education experiences. To overcome this mishap, African American women's experience should be disaggregated from those of Euro-American women and African American males. In order to separate African American women's experiences, a phenomenological research design and theoretical framework, such as Black feminist thought are prudent. The purpose of this descriptive phenomenological …

Ecology, Phylogenetics, And Conservation Of Draba Asterophora Complex: A Rare, Alpine, Endemic From Lake Tahoe, Usa, Emily Ruth Smith Putnam

Theses and Dissertations

Rare, alpine, endemic species are particularly at risk for extinction. Alpine environments are especially vulnerable to climate change and human impacts, such as ski resort development and snowmaking. Draba asterophora Payson is a rare, alpine species that occurs only in three disjunct mountain-top regions surrounding Lake Tahoe. It is currently threatened by human impacts, such as ski resorts, as well as indirect influences of climate change and therefore in need of better understanding for conservation purposes. Draba asterophora may be able to serve as a case study for other similarly vulnerable, rare, alpine, endemic species with conservation needs. We utilized …

Education Experts Give Tips On Apps For Your Kids, Jim Bakken

Browse All News

No abstract provided.

Today - December 20, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- Colon cancer survivor appreciates LLU Cancer Center and San Manuel Band of Mission Indians
-- Live It: Dr. Joan Sabaté
-- More than 300 motorcyclists bring toys and cheer to patients at Children's Hospital
-- LLUH institution-wide mission statement usage
-- Deck the halls with fine art photographs
-- Coachella Valley residents attend School of Dentistry Palm Desert open house
-- Dentistry professor elected president of California Association of Orthodontics
-- New procedure at LLUMC allows Moreno Valley man to regain his sight
-- LLUH disaster response team joins forces with ADRA to help in super …

Tutor Assisted Vocabulary Support: Easing The Vocabulary Load For Burundian Refugees Studying For The U.S. Citizenship Test, Eleanor Anne Clark

Theses and Dissertations

The focus of this thesis was to develop vocabulary materials to supplement those already in use for emergent literate Burundian refugees preparing for the U.S. Citizenship Test. These learners study in conjunction with the International Rescue Committee in Salt Lake City, Utah, and with volunteer tutors who help them study. The flashcards and supporting activities were designed to better enable tutors to teach learners highly-dense vocabulary items, as well as to provide vocabulary scaffolding support for both learners and tutors and to increase depth of vocabulary knowledge with the target vocabulary. The U.S. Citizenship Test Vocabulary Flashcards and Vocabulary Support …

Let The Music Play

News Releases

No abstract provided.

Statistical And Comparative Phylogeography Of Mexican Freshwater Taxa In Extreme Aquatic Environments, Lyndon M. Coghill

LSU New Orleans Theses and Dissertations

Phylogeography aims to understand the processes that underlie the distribution of genetic variation within and among closely related species. Although the means by which this goal might be achieved differ considerably from those that spawned the field some thirty years ago, the foundation and conceptual breakthroughs made by Avise are nonetheless the same and are as relevant today as they were two decades ago. Namely, patterns of neutral genetic variation among individuals carry the signature of a species’ demographic past, and the spatial and temporal environmental heterogeneity across a species’ geographic range can influence patterns of evolutionary change. Aquatic systems …

High Yield Solvothermal Synthesis Of Hexaniobate Based Nanocomposites Via The Capture Of Preformed Nanoparticles In Scrolled Nanosheets, Shivaprasad Reddy Adireddy

LSU New Orleans Theses and Dissertations

The ability to encapsulate linear nanoparticle (NP) chains in scrolled nanosheets is an important advance in the formation of nanocomposites.These nanopeapods (NPPs) exhibit interesting properties that may not be achieved by individual entities. Consequently, to fully exploit the potential of NPPs, the fabrication of NPPs must focus on producing composites with unique combinations of morphologically uniform nanomaterials. Various methods can produce NPPs, but expanding these methods to a wide variety of material combinations can be difficult. Recent work in our group has resulted in the in situ formation of peapod-like structures based on chains of cobalt NPs. Building on this …

Ultra-Low Temperature Measurements Of London Penetration Depth In Iron Selenide Telluride Superconductors, Andrei Diaconu

LSU New Orleans Theses and Dissertations

The newly discovered iron based superconductors have captivated the attention of the scientific community due to the unusual mechanism behind their superconductivity and their promise as the next generation high temperature superconductors. After a century of superconductor research, the physical mechanism behind high temperature superconductivity is still not understood. These new materials bring renewed hope in elucidating the pairing mechanism responsible with high temperature superconductors and achieving the ultimate goal of the field, room temperature superconductivity. Consequently, a deeper understanding of the intriguing properties of iron based materials is essential.

A great deal about the pairing mechanism of Cooper electron …

Experiences And Perceptions Of Novice Associate Degree Nursing Faculty Assuming A Classroom Instructors Role, Mary N. Fontenelle

LSU New Orleans Theses and Dissertations

The purpose of this research was to explore the classroom experiences and perceptions of novice faculty in the classroom setting of an Associate Degree of Nursing programs, located in community colleges. The transition from expert practitioner to novice teacher can be a difficult experience for new classroom nursing instructors. Novice nursing faculty often has very limited educational preparation or background in classroom instruction skills. Nursing research, typically conducted at university level, has minimal applicability for the community college nursing programs. Community colleges educate sixty percent of the graduate Registered Nurses in the United States and have scant research into their …

Transcriptional Co-Repressor Response Of Arabidopsis Thaliana To Different Abiotic Stress, Bhuwan Guragain

LSU New Orleans Theses and Dissertations

Plants adapt to the complex environmental challenges by regulating their gene expression. Analyses of plant genomes have identified many genes that are either expressed or repressed during environmental stress. However we do not have much information on gene repression. Transcriptional repression in Arabidopsis thaliana is caused by co-repressors that lack the DNA binding domain and are recruited by transcription factors to regulate target gene expression. The Sridhar lab has identified co-repressors SLK1, SLK2, and LUH, which prevent the expression of stress response genes under non-stress conditions. Arabidopsis transgenic lines expressing the GUS under the control of co-repressor’s promoter were created, …

The Impact Of The Affordable Care Act On The Safety-Net. A Focus On Two Community-Based Clinics Serving Latin@ Immigrants In The Greater New Orleans Region, Rosa Herrin

LSU New Orleans Theses and Dissertations

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Latin@ immigrants face many obstacles to affordable healthcare that push them to disproportionately rely on the primary safety-net for their healthcare needs. This system is mostly funded with public monies that will be significantly reduced when Affordable Care Act is fully implemented. Since undocumented Latin@ immigrants are prohibited from accessing federally funded healthcare, they will be left out of the health care reform. This thesis examines two community-based clinics in the Greater New Orleans area that serve this population, and have developed linguistically and culturally appropriate programs that address its needs. The New Orleans Faith Health Alliance and Common-Ground …

Perceptions Of Women's Teams Coaches Regarding Gender Equity And Title Ix Compliance In Community Colleges, Cynthia A. Kenney

LSU New Orleans Theses and Dissertations

Title IX was enacted over 40 years ago, and although there have been marked increases in the number of girls and women participating in athletics at every level, gender equity in athletics continues to be a concern. This is especially evident at the community college level. Title IX requires equity in the areas of opportunities for participation, opportunities for financial aid, and equity in benefits and services. This study sought to ascertain perceptions of equity held by community college coaches of women’s teams. A cross-sectional design was used to survey coaches from all regions of the NJCAA who were listed …

Clients' Perceptions Of Their Counseling Experiences For Trauma Related To Anesthesia Awareness (Aa), N. Arlene Magee

LSU New Orleans Theses and Dissertations

Each year in the United States, approximately 81 million individuals receive surgeries in which .1% to .2% (20,000 to 40,000/20 million) experience Anesthesia Awareness (AA). More than 50% of the AA cases result in mental distress or Posttraumatic Stress Disorder (PTSD). Because the percentage of AA cases among surgeries makes it appear to be a rare occurrence, and because it has received rather limited research attention, I decided to undertake an interpretative phenomenological analysis to discover AA clients’ perceptions of their counseling experience, and encourage development of therapeutic interventions to meet their needs.

The broad research question for my study …

Estimation, Decision And Applications To Target Tracking, Yu Liu

LSU New Orleans Theses and Dissertations

This dissertation mainly consists of three parts. The first part proposes generalized linear minimum mean-square error (GLMMSE) estimation for nonlinear point estimation. The second part proposes a recursive joint decision and estimation (RJDE) algorithm for joint decision and estimation (JDE). The third part analyzes the performance of sequential probability ratio test (SPRT) when the log-likelihood ratios (LLR) are independent but not identically distributed.

The linear minimum mean-square error (LMMSE) estimation plays an important role in nonlinear estimation. It searches for the best estimator in the set of all estimators that are linear in the measurement. A GLMMSE estimation framework is …

Synthesis Of Novel Azetidines, Amber Thaxton

LSU New Orleans Theses and Dissertations

Azetidine is a four-membered nitrogen-containing heterocyclic ring that has recently received a great deal of attention as a molecular scaffold for the design and preparation of biologically active compounds. Structure-activity studies employing functionalized azetidines have led to the development of variety of drug molecules and clinical candidates encompassing a broad spectrum of biological activities.

Herein, the synthesis a novel series of 3-aryl-3-arylmethoxyazetidines is described. Selected 3-aryl-3-arylmethoxyazetidines were evaluated for their binding affinity to multiple monoaminergic transporters for the potential treatment of methamphetamine addiction. It was discovered that this scaffold exhibits high binding affinity (nM) for both the serotonin and dopamine …

The Effects Of Chronic Simvastatin Treatment On The Expression Of Behavioral Symptoms In A Transgenic Mouse Model Of Huntington’S Disease, Ashley Whitmarsh

LSU New Orleans Theses and Dissertations

Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. An unstable CAG expansion within the gene normally encoding for the Huntingtin protein is responsible. The expanded mutant form of Huntingtin and the putative protein co-factor Rhes interact and cause cell death within the striatum. We hypothesized chronic treatment with simvastatin, a cholesterol lowering drug, would disrupt the biosynthetical pathway which gives both Rhes and its target cells binding sites and render Rhes inactive. Healthy and HD mice were treated with simvastatin or a vehicle. Animals’ motor behavior was assessed with three separate tests over …

Effects Of Prescribed Burns On Grassland Breeding Birds At Mississippi Sandhill Crane National Wildlife Refuge, Elizabeth A. Ruffman

LSU New Orleans Theses and Dissertations

There has been a critical decline in grassland bird populations due to habitat fragmentation and deterioration, and suppression of natural fires. Alteration of the disturbance cycle may lead to changes in vegetation structure and thus habitat suitability for breeding grassland birds. Management practices at the Mississippi Sandhill Crane National Wildlife Refuge, including the use of prescribed fire, are in need of evaluation. My study asked what frequency of prescribed burns is necessary to support breeding grassland birds and whether vegetation structure varies among burn units. In this study, bird abundance and species richness did not differ significantly among burn units …

Cultivating Educational Resilience: An Examination Of Teacher-Student Interactions In The Elementary Classroom, Hazel S. Parker

LSU New Orleans Theses and Dissertations

No abstract provided.

Committee Of Public Accounts Debate - Friday, 20 Dec 2013: Nama – Annual Report And Financial Statements 2012, Ireland: Oireachtas

Documents

No abstract provided.

The Good Killing, Alex F. Aaron

LSU New Orleans Theses and Dissertations

This paper will provide a far-ranging analysis of the relevant aspects of the filmmaking process as it pertains to the development and production of the thesis project, The Good Killing. This analysis will include both a detailed, biographic overview of the making of the film, as well as an in-depth critique of the creative decision-making and practical methodology that guided the production. In this regard, special attention will be first be given to how the project was initially conceived, and, broadly speaking, what was originally intended. Secondly, proceeding sections will examine key elements of the filmmaker’s technical planning, performance, …