Digital Commons Network^™

The Osh Family Of Proteins And Their Role In Caloric Restriction-Mediated Lifespan Extension In The Budding Yeast Saccharomyces Cerevisiae, William Douglas Craft

Theses and Dissertations

Oxysterol-binding protein homolouges (OSH) have been implicated in mediating non-vesicular sterol transport. Caloric restriction (CR) down-regulates sterol synthesis in a variety of organisms, including the budding yeast Saccharomyces cerevisiae. OSH6, when up-regulated, extends replicative lifespan. In contrast, OSH5 up-regulation shortens replicative lifespan. In this thesis I obtained evidence to show that the deletion of OSH5 extends replicative lifespan in normal media. Deletion of OSH5 in the presence of caloric restriction blocks the lifespan-extending properties of the CR media. My data demonstrate that the total cellular sterol levels of the longevity mutants are indistinguishable from that of wild type. This suggests …

Coalescence In Confinement: Cultural Synthesis And Identity In Michi Tanaka's Community Life, Kimberly L. Sanders

Theses and Dissertations

Community Life by Michi Tanaka was one of eight government commissioned murals created by students at Rohwer Relocation Center in 1944 illustrating the Japanese American evacuation and relocation. The final versions of these works no longer exist. The preparatory drafts, however, remain intact and provide valuable information regarding the artists' experiences at Rohwer. Through an iconographic analysis of Tanaka's mural draft and an exploration of themes and principal elements in her life at camp such as religion, fashion and socialization, this thesis suggests that Community Life illustrates a cultural synthesis between two disparate cultures. This synthesis influenced the development of …

In Ambiguous Battle: The Promise (And Pathos) Of Public Domain Day, 2014, Jennifer Jenkins

Duke Law & Technology Review

On the first day of each year, Public Domain Day celebrates the moment when copyrights expire, and books, films, songs, and other creative works enter the public domain, where they become, in Justice Brandeis’s words, “free as the air to common use.” Educators, students, artists, and fans can use them with neither permission nor payment. Online archives can digitize and make them fully available without the threat of lawsuits or licensing demands. Sadly, in the United States, as a result of copyright term extensions, not a single published work will enter the public domain in 2014. In fact, almost no …

Convective Heat Transfer In Square And Cylindrical Porous Annulus / Salman Ahamed Khan Jagirdar, Jagirdar Salman Ahamed Khan

Student Works (2010-2019)

The convective heat transfer in porous media has attracted the considerable attention in the past few decades due to its wide applicability in various fields. The present work focuses on investigating the various aspects of convection such as conjugate heat transfer, conjugate double diffusion and mixed convection analysis with thermal equilibrium and thermal non-equilibrium modeling. The finite element method is used to discretize the governing non-linear partial differential equations. Galerkins method has been employed to accomplish the element stiffness matrix. An in-house computer code was developed to solve the resulting equations that describe the behavior of heat transfer in porous …

Infrared Vibrational Spectroscopy Analysis Of Selected Biomolecules, Busra Ergul

Theses and Dissertations

Fourier transform infrared (FTIR) spectroscopy is a useful tool to examine biological molecules for noninvasive measurements. This research has focused on the determination of concentrations of four important biomolecules, glucose, gluconic acid, hydrogen peroxide (H2O2), and dopamine by FTIR. It is crucial to determine blood glucose levels for diabetes diagnosis. H2O2 is an important biomolecule having implications in aging and aging related diseases. Gluconic acid is important in food and pharmaceutical industries, and dopamine plays a key role in brain activity. In this work, first, glucose, gluconic acid, and H2O2 in aqueous solutions have been studied by using FTIR. Standard …

Nicotine Exploits A Copi-Mediated Process For Chaperone-Mediated Up-Regulation Of Its Receptors, Brandon J. Henderson, Rahul Srinivasan, Weston A. Nichols, Crystal N. Dilworth, Diana F. Gutierrez, Elisha D. W. Mackey, Sheri Mckinney, Ryan M. Drenan, Christopher I. Richards, Henry A. Lester

Chemistry Faculty Publications

Chronic exposure to nicotine up-regulates high sensitivity nicotinic acetylcholine receptors (nAChRs) in the brain. This up-regulation partially underlies addiction and may also contribute to protection against Parkinson's disease. nAChRs containing the α6 subunit (α6* nAChRs) are expressed in neurons in several brain regions, but comparatively little is known about the effect of chronic nicotine on these nAChRs. We report here that nicotine up-regulates α6* nAChRs in several mouse brain regions (substantia nigra pars compacta, ventral tegmental area, medial habenula, and superior colliculus) and in neuroblastoma 2a cells. We present evidence that a coat protein complex I (COPI)-mediated process mediates this …

Arkansas's Early Home Demonstration Club Members: Making The Work Their Own, Elizabeth A. Hill

Theses and Dissertations

In its attempt to retain the nation's farmers and farm families on the land during the early twentieth century, the U. S. Department of Agriculture found that the situation in the South was particularly problematic as it included dilapidated farm homes, malnutrition, and "poverty of spirit." In order to combat these deficiencies, the home demonstration program taught farm women improved methods for accomplishing their household responsibilities. It also encouraged the women to better their families' living conditions through home improvements and labor-saving devices. This study explores how Arkansas's early home demonstration club members accepted, within their own limitations and spheres …

Luxury Or Necessity: Constructing Little Rock City Hall, Joshua Blair Hart

Theses and Dissertations

This thesis analyzes the construction of Little Rock, Arkansas City Hall. It provides a background of local architecture and history set against broader trends in United States Public Architecture. In particular, the paper explores the Pulaski County [Arkansas] Chancery Court case filed by attorney's for J.N. Hieskell against Mayor W.E. Lenon. Little Rock City Hall was designed by Charles Thompson, an exploration of Thompson's life and projects are also included in this paper. The appendices provide the full text ruling of the Chancery Court as well as Mayor Lenon's response to plaintiffs against him.

Praktik Governance Perbankan Indonesia Ditinjau Dari Aspek Risiko, Erwin Harinurdin, Asti Setiawati, Wahyu Nofiantoro

Jurnal Vokasi Indonesia

Performance -based banking structures Indonesia does not have a normal life characters banking and still largely determined by the ideological and political policies of the government. Banking recovery by using a very protective manner, such as from the purchase of government bonds with limited or margin lending and guaranteed withdrawal. Various indicators such as bank loan-deposit ratio ( LDR ) and the structure of third-party funds that are still dominated by short-term funds such as checking and savings shows that the bank has not been able to carry out its primary function in the economic system, intermediation. In the framework …

Industri Perbankan Yang Terkonsentrasiapakah Tetap Dapat Berkompetisi?Kasus Perbankan Syariah, Sancoko Sancoko

Jurnal Vokasi Indonesia

This paperdiscusses theconditions ofcompetitionbankingindustryin Indonesia, especiallyIslamic Bankingentity. Islamic Bankbecame the objectof research because significant growth in industrial banking.This studyuses a quantitative approachwith adescriptivedesign. Source ofdata used fromindividualbank's annual reporton the websiteof BankIndonesia fromthe period 2008-2011. Tomeasureaspects ofcompetition Islamic Bankingusing Panzar&Rosestatisticmethods. Results of studyshowed thatIslamic banking came into condition of monopolisticcompetitition structure.

Peningkatan Keterlibatan Mahasiswa Dalampembelajaran Biostatistik Dengan Metode Kooperatifmelalui Media Lembar Kerja Mahasiswa (Lkm) Di Program Studi Perumahsakitan, Nia Murniati, Supriadi Supriadi, Tri Gunadi

Jurnal Vokasi Indonesia

This research is motivated by the lack of passionate students of the Program Studi Perumahsakitan Vokasi in the following study courses Biostatistics, because the teaching method does not make the students become active and participate. Consequently Biostatistics courses often leave some students are forced to repeat the due credit limit does not reach the threshold value eventually pass (C) and of course is very detrimental to the student having to repeat the course credit until they intern (last semester). This study is a class act with the entire student subjects RS1 50 people Academic Year 2012/2013 in the University of …

Jonathan Green, Charlie Schlenker

Interviews for WGLT

"How Do You Get To Carnegie Hall? Write - As Well As Practice"

An Illinois Wesleyan University composer recently had a work of his debut at Carnegie Hall. WGLT's Charlie Schlenker has more.

The Uncertain Future Of A 'New Type' Of Us-China Relationship　不透明な「新型」米中関係の未来, Mel Gurtov

Political Science Faculty Publications and Presentations

President Xi Jinping's call for a "new type of great-power relationship" in meetings in 2013 with President Obama raises important questions about the future of US-China relations. On the surface, it appeared that the two leaders were on the same page. At the June summit, Obama agreed with Xi that "working together cooperatively" and bringing US-China relations "to a new level" were sound ideas. When the G-20 countries convened at St. Petersburg in September, Obama said of Xi’s proposed new model: "we agreed to continue to build a new model of great power relations based on practical cooperation and constructively …

Interactive Virtual Suturing Simulations: Enhancement Of Student Learning In Veterinary Medicine, Charles B. Boyd, Amy J. Staton

Morehead State Theses and Dissertations

A capstone submitted in partial fulfillment of the requirements for the degree of Doctor of Education in the College of Education at Morehead State University by Christine B. Boyd and Amy J. Staton on December 29, 2013.

Deafdigest: Blue Edition, December 29, 2013, Barry Strassler

DeafDigest Blue 2013

No abstract provided.

Enter Conference 2014 Programme, Patrick Horan

Other resources

No abstract provided.

Sphingosine-1-Phosphate-Mediated Mobilization Of Hematopoietic Stem/Progenitor Cells During Intravascular Hemolysis Requires Attenuation Of Sdf-1-Cxcr4 Retention Signaling In Bone Marrow, Kasia Mierzejewska, Yuri M. Klyachkin, Janina Ratajczak, Ahmed Abdel-Latif, Magda Kucia, Mariusz Z. Ratajczak

Saha Cardiovascular Research Center Faculty Publications

Sphingosine-1-phosphate (S1P) is a crucial chemotactic factor in peripheral blood (PB) involved in the mobilization process and egress of hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM). Since S1P is present at high levels in erythrocytes, one might assume that, by increasing the plasma S1P level, the hemolysis of red blood cells would induce mobilization of HSPCs. To test this assumption, we induced hemolysis in mice by employing phenylhydrazine (PHZ). We observed that doubling the S1P level in PB from damaged erythrocytes induced only a marginally increased level of mobilization. However, if mice were exposed to PHZ together with the …

Journalism Students Gain Valuable Media Experience, Michael Newsom

University of Mississippi News

UM partnerships with media help students get their work published, aired

Localized Corrosion Behavior Of Sensitized 304 Stainless Steel By Scanning Reference Electrode Technique, Chen-Qing Ye, Rong-Gang Hu, Rui-Qing Hou, Xiao-Ping Wang, Rong-Gui Du, Chang-Jian Lin

Journal of Electrochemistry

Based on a home-built setup of scanning reference electrode technique, and combined with conventional electrochemical measurements, the localized corrosion behavior of sensitized 304 stainless steel (304ss) had been investigated in this work. The results showed that, the non-sensitized 304ss or 304ss sensitized at 550 oC was susceptible to pitting; while 304ss sensitized at 650 oC or 750 oC suffered severe intergranular corrosion in 10% FeCl3 solution.

Prevalence Of Drug Resistance Among New Cases Of Pulmonary Tuberculosis, Zaid Mohammed Ali Hamandi, Adnan M.Aljubouri

Iraqi Postgraduate Medical Journal

ABSTRACT: BACKGROUND: Tuberculosis (TB) is a disease that has affected humankind throughout recorded history and before.Presently, the number of deaths caused by TB worldwide exceeds that caused by any other organism. Drug-resistant tuberculosis is a man-made problem. Poor management can lead to the selection of M. tuberculosis with mutations conferring resistance to antituberculous drugs. Drug resistance is divided into two types: primary (resistance in persons who have never received anti-tuberculosis drugs for more than 1 month. These patients are initially infected with drug-resistant strains) and secondary, acquired, (resistance to anti-tuberculosis drugs, which arises during treatment due to poor compliance or …

Biofilm Formation On Intrauterine Device And Associated Infections, Sabah Abd Al-Kareem Al-Kattan, Daniz Tarik Burhan, Shafaq Tarik Burhan

Iraqi Postgraduate Medical Journal

Shafaq Tarik Burhan ABSTRACT: BACKGROUND: Intrauterine devices are highly effective methods of contraception; but considered to cause pelvic inflammatory diseases by its colonization by bacteria and /or fungi and form biofilms consisting of layers of host cells and bacteria or fungi embedded within a matrix material. OBJECTIVE: To screen the microbial biofilms on intrauterine devices, and its associated infection in vagina and cervix in intrauterine devices users. METHODS: A case series design was adopted, composed of 50 participants. High vaginal and cervical swabs were taken and intrauterine devices were removed and sent for microbiological examination. RESULTS: Eighty four percent of …

Incdence Of Rheumatoid Arthritis [2001 To 2011], Ali Mohammed Hussein Alkazzaz

Iraqi Postgraduate Medical Journal

ABSTRACT: BACKGROUND : The incidence of rheumatoid arthritis[RA] varies from country to another which not depend on genetic bases alone but can explained by environmental exposure and genetic and environmental interaction, area of military conflict ,there was stress induced pathway that elevates the risk for rheumatoid arthritis, in Iraq rheumatoid was 1% of population in 1975. OBJECTIVE: To evaluate incidence of RA in Babylon –Iraq from 2001-2011 PATIENTS AND METHODS: This study was done to examine the incidence of RA in Babylon between 2001-2011 by Retrospective cohort study in Merjan Teaching Hospital ,Rheumatology unit .Data included sex .birth year ,residency …

Wood County Project Homeless Connect: Final Report For Event Held October 16, 2013, Melissa W. Burek, Judith A. Leary, Adam Watkins, Mamta Ojha

Criminal Justice Faculty Publications

On October 16, 2013, Wood County, Ohio held their first Project Homeless Connect event at St. Mark’s Lutheran Church in Bowling Green, Ohio. Project Homeless Connect (PHC) is designed to provide immediate goods and services to homeless individuals and those nearing homelessness. It provides basic needs and critical services in one day at one location. It originated in San Francisco and was later adopted and revised by the U.S. Interagency Council on Homelessness (USICH) to decrease homelessness in major American cities (Knetch & Martinez, 2009). PHC was created following the premises of the former President George W. Bush Administration’s policy …

The Murray Ledger And Times, December 27, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

The Role Of Astrocyte And Purinergic Signaling In Rtn Chemoreception, Ian C. Wenker

Doctoral Dissertations

Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue pH/CO2. It is particularly important during sleep and its disruption has been associated with certain pathologies, including central sleep apnea and central congenital hypoventilation syndrome. A region of the brainstem called the retrotrapezoid nucleus (RTN) is thought to be an important site of central chemoreception. Recent evidence suggests that RTN chemoreception involves two mechanisms. The first appears to be H+-mediated activation of neurons via inhibition of pH-sensitive potassium channels. More recently, a second sensing mechanism has been identified; paracrine release of ATP in …

Hip-Hop, Medellín And Social Change, Veronica Henao Posada

Master's Theses

This study explores the ways in which the Hip-hop movement is producing social change in Medellín, Colombia. Looking specifically at a Hip-hop school called Cuatro Elementos Skuela, which exists autonomously and with very little state support in the Medellín neighborhood of Aranjuez, I argue that young people are contributing to the reconstruction of the city’s social, cultural and economic fabric. I start by explaining the historical context of Medellín, describing the different sets of conflicts that unleashed high levels of violence and caused the fragmentation of the social, cultural and economic fabric. Moreover, I review the role of the …

Navigating The Political Divide: Lessons From Lincoln, Lmu Law Review

Lincoln Memorial University Law Review Archive

This edition is comprised of Lincoln Memorial University Duncan School of Law’s symposium “Navigating the Political Divide: Lesson from Lincoln,” held April 20, 2012 in Knoxville, TN. Authors and speakers within this volume include: M. Akram Faizer, Charles M. Hubbard, Mark Halperin, Helen E. Lee, Michael Steele, Siegfried Wiessner, Nicholas S. Davenport, and Tracy P. Knight.

Obit - June Marie Krutza, Journal Gazette-Times Courier

EIU in the News

Dr. Krutza joined the art faculty at Eastern Illinois State College in 1952. Hired to teach Art education and high school art at Buzzard Lab School, she later taught undergraduate and graduate courses in a variety of media including jewelry and textiles, but ceramics was her love. She was honored with a Distinguished Faculty Award in 1987. Professor Krutza retired from Eastern Illinois University in 1989.

Vol.41 N.22 December 26th 2013, Brown Publishing Company

Black Voice News

No abstract provided.

Timing And Spectroscopy Requirements For A Plastic Scintillating Fiber Bundle Time-Of-Flight Neutron Spectrometer, Paul A. Clement

Theses and Dissertations

The design parameters of a Time-of-Flight (TOF) neutron spectrometer composed of BCF-12 plastic scintillating fibers were investigated. A GEANT4 transport model was developed for analyzing the interaction of 2.5 MeV neutrons with a 14 x 14 BCF-12 fiber bundle. The bundle simulation demonstrated that 0.359% of all neutrons incident on the bundle will double scatter. The timing and data collection e efficiencies of a Tektronix DPO7104 series digital oscilloscope were examined to determine the signal processing requirements for future fiber bundle measurements. The minimum detectable neutron energy was computed by taking into account the bundle scintillation e efficiency, light collection …