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2013

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An Educational Framework For Managing And Supporting Medication Adherence In Europe, S White, W Clyne, C Mshelia Jan 2013

An Educational Framework For Managing And Supporting Medication Adherence In Europe, S White, W Clyne, C Mshelia

Peninsula Medical School

Introduction: Decisions about taking medicines ultimately lie with patients, so health professionals need to engage with patients to manage and support medication adherence. Health professionals need appropriate education to do this. We aimed to develop an educational framework for health professionals in Europe for managing and supporting medication adherence. Description of the framework: The resulting educational framework comprises a competency framework, a curriculum, a diagnostic tool for competence assessment and a reading list. Quality assurance: Framework development started from a 2007 competency framework for shared decision-making. A literature review and a Europe-wide consultation were conducted and the ABC research team …


The Emergence Of Two Anti-Phase Oscillatory Neural Populations In A Computational Model Of The Parkinsonian Globus Pallidus, R Merrison-Hort, R Borisyuk Jan 2013

The Emergence Of Two Anti-Phase Oscillatory Neural Populations In A Computational Model Of The Parkinsonian Globus Pallidus, R Merrison-Hort, R Borisyuk

School of Engineering, Computing and Mathematics

Experiments in rodent models of Parkinson's disease have demonstrated a prominent increase of oscillatory firing patterns in neurons within the Parkinsonian globus pallidus (GP) which may underlie some of the motor symptoms of the disease. There are two main pathways from the cortex to GP: via the striatum and via the subthalamic nucleus (STN), but it is not known how these inputs sculpt the pathological pallidal firing patterns. To study this we developed a novel neural network model of conductance-based spiking pallidal neurons with cortex-modulated input from STN neurons. Our results support the hypothesis that entrainment occurs primarily via the …