Digital Commons Network^™

Four Questions About Fracking, Thomas W. Merrill

Case Western Reserve Law Review

No abstract provided.

Hydrofracking: State Preemption, Local Power, And Cooperative Governance, John R. Nolon, Steven E. Gavin

Case Western Reserve Law Review

No abstract provided.

Shale Oil And Gas State Regulatory Issues And Trends, Christopher S. Kulander

Case Western Reserve Law Review

No abstract provided.

The Gifted Commitment: Gifted Education's Unrecognized Relevance In "Thorough And Efficient" Public Schools, Patrick Haney

Case Western Reserve Law Review

No abstract provided.

Meat-Wise Eating Habits, J. Haycock, K. Anderson, Roslynn Brain

Environment and Society Faculty Publications

Whether from a cow, pig, bird, fish, or other domestic or game animal, meat is universally enjoyed as part of the cultural culinary experience. It is also an excellent source of protein, which is important for a healthy body. Many people who eat meat, however, are not aware of the impact their consumption has on the environment. This guide provides a set of quick facts and action tools to make wiser choices concerning meat consumption.

Designing Your Home For Maximum Natural Lighting, P. Bytheway, Roslynn Brain

Environment and Society Faculty Publications

There are many benefits to having more natural light in your home. The most obvious of these are the savings you can achieve with a reduced utility bill. According to the U.S. Department of Energy (2012), about 10% of household electricity usage comes from lighting. The more natural light you have in your house, the less lights you have to turn on, and the less electricity you use. Another benefit, also related to energy use, is natural light can help heat homes. One of the best reasons to design your home for natural light involves the health benefits gained through …

Biking As An Alternative Mode Of Transportation, Roslynn Brain, Jared Stapp

Environment and Society Faculty Publications

With this fact sheet, you can overcome common barriers keeping you from becoming your own mode of transportation, and bettering your life because of it. According to the U.S. Census Bureau, “creating new infrastructure and altering existing infrastructure to accommodate bicycling and walking has become a goal for several metropolitan planning organizations across the United States” (McKenzie & Rapino, 2011). Now is a great time to take advantage of this shifting focus away from vehicle commuting and delve into a healthier and cheaper mode of transportation: Cycling.

Uintah Basin Revisited - 2012-2013 Bioregional Planning Studio Project, Richard E. Toth, Matthew Coombs, C Michael Gottfredson, Tyler Allen

Environment and Society Faculty Publications

Since the Uintah Basin Research Conference in 2007, residents of the area have witnessed a consistent level of land-use development throughout the region. Portions of that growth and development have precipitated the need to develop a landscape-level plan in order to maintain the context of their region and community identity in the coming years. The purpose of this study is to research and develop a process that identifies current and future land-use issues throughout the Uintah Basin. The identification of these issues by various stakeholders will help to provide a framework for future policy decisions.

Continuity Of Cancer Care: Where Do Primary Care Practitioners Fit In?, M Jiwa, A Mcmanus, A Dadich

Medical Papers and Journal Articles

Cancer is the leading cause of illness in Australia and is a national health priority. Primary care in Australia is well positioned to support individuals diagnosed with cancer and their family/caretakers. However, obstacles exist that impact on the quality and continuity of care that primary care providers and community health professionals can provide. A rapid review of the research available revealed that the knowledge, attitudes and beliefs held by health professionals and patients can impact engagement in early detection, treatment and follow-up care. Health professionals have limited knowledge of evidence-based practices, while cancer literacy among minority groups, including Aboriginal Australians, …

Contributions Of Ocular Surface Components To Matrix-Metalloproteinases (Mmp)-2 And Mmp-9 In Feline Tears Following Corneal Epithelial Wounding, A Petznick, M Madigan, Q Garrett, D Sweeney, M Evans

Medical Papers and Journal Articles

Purpose: This study investigated ocular surface components that contribute to matrix-metalloproteinase (MMP)-2 and MMP-9 found in tears following corneal epithelial wounding.

Methods: Laboratory short-haired cats underwent corneal epithelial debridement in one randomly chosen eye (n = 18). Eyeflush tears were collected at baseline and during various healing stages. Procedural control eyes (identical experimental protocol as wounded eyes except for wounding, n = 5) served as controls for tear analysis. MMP activity was analyzed in tears using gelatin zymography. MMP staining patterns were evaluated in ocular tissues using immunohistochemistry and used to determine MMP expression sites responsible for tear-derived MMPs.

Results: …

Efficacy Of Osmoprotectants On Prevention And Treatment Of Murine Dry Eye, W Chen, X Zhang, J Li, Y Wang, Q Chen, C Hou, Q Garrett

Medical Papers and Journal Articles

Purpose: To evaluate the efficacy of osmoprotectants on prevention and treatment of dry eye in a murine model.

Methods: Dry eye was induced in mice by using an intelligently controlled environmental system (ICES). Osmoprotectants betaine, L-carnitine, erythritol, or vehicle (PBS) were topically administered to eyes four times daily following two schedules: schedule 1 (modeling prevention): dosing started at the beginning of housing in ICES and lasted for 21 or 35 days; schedule 2 (modeling treatment): dosing started after ICES-housed mice developed dry eye (day 21), continuing until day 35. Treatment efficacy was evaluated for corneal fluorescein staining; corneal epithelial apoptosis …

Decrease In Hyperosmotic Stress-Induced Corneal Epithelial Cell Apoptosis By L-Carnitine, N Khandekar, M Willcox, S Shih, P Simmons, J Vehige, Q Garrett

Medical Papers and Journal Articles

Purpose: To characterize the osmoprotective properties of L-carnitine on human corneal epithelial cell volume and apoptosis during hyperosmotic stress.

Methods: Human corneal limbal epithelial (HCLE) cells were exposed to culture medium at 300 mOsm (isotonic) or 500 mOsm (hyperosmotic) with or without L-carnitine (10 mM). Induction of apoptosis was detected by quantifying the proteolytic activity of caspase-8, caspase-9, and caspase-3/7 using caspase activity assays, the expression of tumor necrosis factor (TNF)-α with enzyme-linked immunosorbent assay, and annexin V/propidium iodide staining of HCLE cells evaluated with confocal microscopy and flow cytometry. Cell volume changes in response to hyperosmotic stress were analyzed …

Assessment Of Potential Anti-Cancer Stem Cell Activity Of Marine Algal Compounds Using An In Vitro Mammosphere Assay, J De La Mare, J Sterrenberg, M Sukhthankar, M Chiwakata, D Beukes, G Blatch, A Edkins

Medical Papers and Journal Articles

Background: The cancer stem cell (CSC) theory proposes that tumours arise from and are sustained by a subpopulation of cells with both cancer and stem cell properties. One of the key hallmarks of CSCs is the ability to grow anchorage-independently under serum-free culture conditions resulting in the formation of tumourspheres. It has further been reported that these cells are resistant to traditional chemotherapeutic agents.

Methods: In this study, the tumoursphere assay was validated in MCF-7 cells and used to screen novel marine algal compounds for potential anti-cancer stem cell (CSC) activity in vitro.

Results: MCF-7 breast cancer cells were observed …

“It Is Not A Disease We Treat, But A Person”: Medical Students’ Reflections On Their First Rotations To An Oncology And Palliative Care Unit, John Kearsley, Elizabeth Lobb

Health Sciences Papers and Journal Articles

The vast array of technologic advances in medicine has transformed traditional medical practice and education. However, these advances are not without their critics (1-7). Some medical educators and students suggest that the “final product” of medical education has many of the characteristics of the applied scientist (2) rather than those of the humane physician-healer (8). Many medical students bring to their studies an idealism and an empathy that, for many, is quickly eroded over time. According to Bellini and Shea (4), they may never fully recover their empathy. Several studies have concluded that a significant decline in empathy occurs during …

Online Prostate Cancer Screening Decision Aid For At-Risk Men: A Randomized Trial, Kaaren J. Watts, Bettina Meiser, Claire E. Wakefield, Alexandra Barratt, Kirsten Howard, Benjamin C. Cheah, Graham J. Mann, Elizabeth Lobb, Clara Gaff, Manish I. Patel

Health Sciences Papers and Journal Articles

Objective: This study examines the efficacy of an online decision aid (DA) for men with a family history of prostate cancer.

Methods: Unaffected Australian men (40 - 79 years) with at least one affected relative completed the first online questionnaire, were randomized to read either the tailored DA (intervention) or nontailored information about prostate cancer screening (control), then completed a questionnaire postreading and 12 months later. The primary outcome was decisional conflict regarding prostate specific antigen (PSA) testing. The impact of the DA on longitudinal outcomes was analyzed by using random intercept mixed effects models. Logistic and linear regressions were …

The "Specter" Of Cancer: Exploring Secondary Trauma For Health Professionals Providing Cancer Support And Counseling, Lauren Breen, Moira O'Connor, Lauren Y. Hewitt, Elizabeth Lobb

Health Sciences Papers and Journal Articles

Health professionals are vulnerable to occupational stress and tend to report high levels of secondary trauma and burnout; this is especially so for those working in “high-death” contexts such as cancer support and palliative care. In this study, 38 health professionals (psychologists, social workers, pastoral carers/chaplains, nurses, group facilitators, and a medical practitioner) who provide grief support and counseling in cancer and palliative care each participated in a semistructured interview. Qualitatively, a grounded theory analysis revealed four themes: (a) the role of health professionals in supporting people who are experiencing grief and loss issues in the context of cancer, (b) …

Maternal And Infant Infections Stimulate A Rapid Leukocyte Response In Breastmilk, F Hassiotou, A Hepworth, P Metzger, C Lai, N Trengove, P Hartmann, L Filgueira

Health Sciences Papers and Journal Articles

Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and immunomodulatory biomolecules in healthy mother/infant dyads and how they are influenced by infections of the dyad. Consistent with a greater immunological need in the early postpartum period, colostrum contained considerable numbers of leukocytes (13–70% out of total cells) and high levels of immunoglobulins and lactoferrin. Within the first 1–2 weeks postpartum, leukocyte numbers decreased significantly to a low baseline level in mature breastmilk (0–2%) …

Comparison Of Volatile Blends And Nucleotide Sequences Of Two Beauveria Bassiana Isolates Of Different Virulence And Repellency Towards The Termite Macrotermes Michealseni, D. M. Mburu, N. K. Maniania, A. Hassanali

All Peer-Reviewed Publications

Isolates of the fungus Beauveria bassiana have different levels of virulence and repellency against the termite Macrotermes michaelseni. In the present study, we compared the volatile profiles and gene sequences of two isolates of the fungus with different levels of virulence and repellence to the termite. Gas chromatography-mass spectrometric analyses showed quantitative and qualitative differences in the composition of volatiles of the two isolates. The repellencies of synthetic blends of 10 prominent components that mimicked the volatiles of each of the two isolates were significantly different. Subtractive bioassays showed that the repellency of each isolate was due to synergistic effects …

Development Of A Gravid Trap For Collecting Live Malaria Vectors Anopheles Gambiae S.L, Sisay Dugassa, Jenny M. Lindh, Florence Oyieke, Wolfgang R. Mukabana, Steven W. Lindsay, Ulrike Fillinger

All Peer-Reviewed Publications

BACKGROUND: Effective malaria vector control targeting indoor host-seeking mosquitoes has resulted in fewer vectors entering houses in many areas of sub-Saharan Africa, with the proportion of vectors outdoors becoming more important in the transmission of this disease. This study aimed to develop a gravid trap for the outdoor collection of the malaria vector Anopheles gambiae s.l. based on evaluation and modification of commercially available gravid traps. METHODS: Experiments were implemented in an 80 m(2) semi-field system where 200 gravid Anopheles gambiae s.s. were released nightly. The efficacy of the Box, CDC and Frommer updraft gravid traps was compared. The Box …

Construction Workers' Exposure To Crystalline Silica: Literature Review And Analysis, Charles Beaudry, Chantal Dion, Michel Gérin, Guy Perrault, Denis Bégin, Jérôme Lavoué

États de la question, rapports d’expertise et revues de littérature

La silice est un des composés inorganiques les plus répandus dans la nature. Sous la forme cristalline du quartz on la retrouve abondamment dans divers minéraux, dont le granite et le sable. Lorsque des matériaux contenant de la silice cristalline sont manipulés, le quartz peut se retrouver sous forme de poussière en suspension dans l’air. L’inhalation de cette poussière par les travailleurs peut causer diverses maladies des voies respiratoires, dont les plus invalidantes sont la silicose et le cancer pulmonaire.

Dans le secteur de la construction, l’exposition professionnelle à la silice cristalline est fréquente dans plusieurs métiers, en raison de …

Comparison Of The Effects Of Extracts From Three Vitex Plant Species On Anopheles Gambiae S.S. (Diptera: Culicidae) Larvae, Mokua G. Nyamoita, Innocent Ester, Mbwambo H. Zakaria, Lwande Wilber, Ochola J. Bwire, Hassanali Ahmed

All Peer-Reviewed Publications

Acetone and methanol extracts of different parts of three Vitex species (leaves and stem bark of Vitex trifolia, leaves, stem bark and root bark of Vitex schiliebenii and stem and root bark of Vitex payos) were evaluated for their potential to control Anopheles gambiae Giles s.s. larvae (Diptera: Culicidae). The extracts gave different levels and rate of mortality of the larvae. Some (methanol extract of V. trifolia leaves, acetone extracts of stem bark and leaves of V. schiliebenii, acetone extract of root bark of V. payos) caused 100% mortality at 100ppm in 72h, with those of V. schiliebenii and V. …

A New Approach To An Old Problem: Defining Nursing’S Role In Successful Transitions To Long-Term Residential Care, Kyleen Aldrich

Honors College Theses

A growing body of nursing research addresses the transitional period for older adults entering long-term residential care. However, gaps exist in our understanding of nursing’s role in the transition process. Our aim is to examine the available evidence and develop a model of nursing strategies and interventions to ease the transition to long-term care. This model describes interventions that nurses can incorporate into everyday practice.

A literature review was conducted to examine the transitional care needs and interventions for older adults with a goal of developing a model addressing transitions to long-term care.

Most nursing studies provided descriptive information about …

Analysis Of Vitamin D Status At Two Academic Medical Centers And A National Reference Laboratory: Result Patterns Vary By Age, Gender, Season, And Patient Location, Jonathan R. Genzen, Jennifer T. Gosselin, Thomas C. Wilson, Emilian Racila, Matthew D. Krasowski

Psychology Faculty Publications

Background: Testing for 25-hydroxyvitamin D [25(OH)D] has increased dramatically in recent years. The present report compares overall utilization and results for 25(OH)D orders at two academic medical centers - one in New York and one in Iowa – in order to characterize the vitamin D status of our inpatient and outpatient populations. Results are also compared to those from a national reference laboratory to determine whether patterns at these two institutions reflect those observed nationally.

Methods: Retrospective data queries of 25(OH)D orders and results were conducted using the laboratory information systems at Weill Cornell Medical College / New York Presbyterian …

Developmental Changes In Postural Stability During The Performance Of A Precision Manual Task, Jeffrey M. Haddad, Laura J. Claxton, Dawn Melzer, Joseph Hamill, Richard E. A. Van Emmerik

Psychology Faculty Publications

Posture becomes integrated with other goal-directed behaviors early in infancy and continues to develop into the second decade of life. However, the developmental time course over which posture is stabilized relative to the base of support during a dynamic manual precision task has not been examined. Postural-manual integration was assessed in 7-year-olds, 10-year-olds, and adults using a postural-manual task in which task precision (target fitting size) and postural difficulty (reaching distance to a target) were manipulated. The main dependent variable was postural time-to-contact (TtC). Results indicated systematic age effects in which TtC was shortest in the 7-year-olds, increased in the …

Food $Ense Website, Heidi Leblanc, D. Christofferson, E. Milligan

Nutrition, Dietetics, and Food Sciences Faculty Publications

No abstract provided.

Cloud Privacy Audit Framework: A Value-Based Design, David Coss

Theses and Dissertations

The rapid expansion of cloud technology provides enormous capacity, which allows for the collection, dissemination and re-identification of personal information. It is the cloud’s resource capabilities such as these that fuel the concern for privacy. The impetus of these concerns are not too far removed from those expressed by Mason in 1986, when he identified privacy as one of the biggest ethical issues facing the information age. There seems to be continuous ebb and flow relationship with respect to privacy concerns and the development of new information communication technologies such as cloud computing. Privacy issues are a concern to all …

What?: Visual Interpretations Of The Miscommunication Between The Hearing And Deaf, Virginia Shou

Theses and Dissertations

This thesis visualizes the communication challenges both latent and obvious of my daily life as a hard of hearing individual. By focusing on a variety of experiences and examples I demonstrate the implications of a hard of hearing individual’s life. The prints, objects and videos that I have created for my visual thesis aim to enrich the understanding of a broader public on issues regularly faced by Deaf people. At the heart of my work my goal is to generate mutual empathy between the hearing and the Deaf.

The Impact Of Imprecision In Hcv Viral Load Test Results On Clinicians’ Therapeutic Management Decisions And On The Economic Value Of The Test, Roberta M. Madej

Theses and Dissertations

Clinical laboratory test results are integral to patient management. Important aspects of laboratory tests’ contributions are the use of the test information and the role they have in facilitating efficient and effective use of healthcare resources. Methods of measuring those contributions were examined using quantitative HCV RNA test results (HCV VL) in therapeutic management decisions as a model. Test precision is important in those decisions; therefore, the clinical use was evaluated by studying the impact that knowledge of inherent assay imprecision had on clinicians’ decisions. A survey describing a simulated patient at a decision point for HCV triple-combination therapy management …

The Ticking Of The “Biological Clock”: Worry About Future Fertility In Nulliparous Women, Karen E. Kersting

Theses and Dissertations

Abstract

Title: The Ticking of the “Biological Clock”: Worry about Future Fertility in Nulliparous Women

By: Karen Kersting, M.A., M.S.

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University.

Virginia Commonwealth University, 2013.

Major Director: Kathleen M. Ingram, J.D., Ph.D.

Associate Professor of Psychology

Department of Psychology

Modern women are waiting until later in their lives to have children than women of previous generations, a trend influenced by a number of factors including financial stability, dating norms, and career goals and responsibilities. As women age, their fertility may decline …

The Costs Of Occupational Injuries: A Review Of The Literature, Martin Lebeau, Patrice Duguay

États de la question, rapports d’expertise et revues de littérature

Cette revue de littérature s'inscrit dans la volonté institutionnelle de développer des indicateurs économiques de santé et de sécurité au travail, sur lesquels pourra s'appuyer le choix de priorités de recherche, en complément des indicateurs et autres informations déjà utilisés à l'IRSST.

Ce rapport vise plus spécifiquement à identifier, définir et classer les composantes des coûts des lésions professionnelles, ainsi qu'à répertorier les différentes approches économiques qui sont utilisées pour estimer les coûts des lésions professionnelles. Ce rapport ne vise donc pas à répertorier les montants réels ou estimés des coûts des lésions professionnelles que l'on retrouve dans la littérature. …