Digital Commons Network^™

Using Expression Profiling To Understand The Effects Of Chronic Cadmium Exposure On Mcf-7 Breast Cancer Cells, Zelmina Lubovac-Pilav, Daniel M. Borras, Esmeralda Ponce, Maggie Louie

Collected Faculty Scholarship

Cadmium is a metalloestrogen known to activate the estrogen receptor and promote breast cancer cell growth. Previous studies have implicated cadmium in the development of more malignant tumors; however the molecular mechanisms behind this cadmium-induced malignancy remain elusive. Using clonal cell lines derived from exposing breast cancer cells to cadmium for over 6 months (MCF-7-Cd4, -Cd6, -Cd7, -Cd8 and -Cd12), this study aims to identify gene expression signatures associated with chronic cadmium exposure. Our results demonstrate that prolonged cadmium exposure does not merely result in the deregulation of genes but actually leads to a distinctive expression profile. The genes deregulated …

School Teachers. Performance-Based Layoffs And Rehiring. Dismissals. Initiative Statute.

Initiatives

Requires school districts to use a classroom teacher's performance ratings, rather than seniority, to determine layoffs and make rehiring decisions. Requires districts to conduct specified evaluations of each teacher's performance annually. Requires these annual evaluations to measure teacher performance by, at a minimum, student academic progress, classroom observations and instructional practices, parent and student feedback, and teacher partnerships with community members and organizations. Provides that teachers convicted of certain violent, serious, or sexual felonies are to be automatically dismissed and permanently barred from employment as a teacher in the state. Summary of estimate by Legislative Analyst and Director of Finance …

School Teachers. Performance-Based Layoffs And Rehiring. Dismissals. Initiative Statute.

Initiatives

Requires school districts to use a classroom teacher's performance ratings, rather than seniority, to determine layoffs and make rehiring decisions. Requires districts to conduct specified evaluations of each teacher's performance annually. Requires these annual evaluations to measure teacher performance by, at a minimum, student academic progress, classroom observations and instructional practices, parent and student feedback, and teacher partnerships with community members and organizations. Provides that teachers convicted of certain violent, serious, or sexual felonies are to be automatically dismissed and permanently barred from employment as a teacher in the state. Summary of estimate by Legislative Analyst and Director of Finance …

The Murray Ledger And Times, December 20, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Chile’S Once And Future President Michelle Bachelet Wins Election Runoff In A Landslide, Benjamin Witte-Lebhar

NotiSur

No abstract provided.

Purifying The Human Rna-Lariat Debranching Enzyme, Ammar Saigal

Honors Program Theses and Research Projects

This project is my first official research endeavor and it involved becoming acquainted with a large variety of biochemistry and molecular biology techniques. The goal is to elucidate the structure of a protein common to most if not all cells of organisms within the Domain Eukarya, which is one of the three taxonomic domains into which all life is categorized. This is the domain most relevant to human beings as it includes plants, fungi, and animals (from a strictly biologically-taxonomic perspective, the species Homo sapiens to which you and I belong is considered belonging to the Kingdom Animalia [Animal]).

Uab Launches Paired Exchange And Incompatible Kidney Transplant Program, Tyler Greer

Browse All News

No abstract provided.

Winter Commencement: December 20, 2013, University Of North Dakota

UND Commencement Programs

UND Winter Commencement program from December 20, 2013.

Evidence Led Forward Planning - The Case For Capacity Studies, Paul J. Lawlor Mr

Articles

The 2010 Planning and Development Amendment Act requires Local Authorities to include core strategies in their development plans that demonstrate the location, quantum and phasing of development that is proposed to meet their future needs. However, the limited availability of usable data on the issues that enable development (such as land use, transport and open space) make it is difficult for Local Authorities to establish if (and how much) new development can be accommodated in designated areas. Noting that the National Spatial Strategy recommends the use of capacity studies to provide insights on future development scenarios in urban areas, this …

Simulation Training Takes Giant Step Forward, Natalie Wade

Browse All News

No abstract provided.

Today - December 20, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- Colon cancer survivor appreciates LLU Cancer Center and San Manuel Band of Mission Indians
-- Live It: Dr. Joan Sabaté
-- More than 300 motorcyclists bring toys and cheer to patients at Children's Hospital
-- LLUH institution-wide mission statement usage
-- Deck the halls with fine art photographs
-- Coachella Valley residents attend School of Dentistry Palm Desert open house
-- Dentistry professor elected president of California Association of Orthodontics
-- New procedure at LLUMC allows Moreno Valley man to regain his sight
-- LLUH disaster response team joins forces with ADRA to help in super …

Promoting Electrocatalytic Activity Of A Composite Sofc Cathode La0.8Sr0.2Mno3+Δ/Ce0.8Gd0.2O2-Δ With Molten Carbonates, Yunhui Gong, Xue Li, Lingling Zhang, Whitney Tharp, Changyong Qin, Kevin Huang

Faculty Publications

The effect of molten carbonates (MCs) on polarization resistance (R_P), a direct measure of oxygen reduction reaction (ORR) activity, of a composite La_0.8Sr_0.2MnO_3+δ/Ce_0.8Gd_0.2O_2-δ (LSM/GDC) solid oxide fuel cell (SOFC) cathode has been systematically investigated in this study over a temperature range of 550–650°C and partial pressure of oxygen (pO₂) span of 10⁻³ ∼ 1 atm. It is shown that the LSM/GDC cathode, either in the pristine or MC-modified states, can be generally modeled by two consecutive parallel circuits consisting of a resistance and a …

Emu Today, December 20, 2013, Eastern Michigan University

EMU Today

No abstract provided.

Do Organizational Culture And Climate Matter For Successful Client Outcomes?, David A. Patterson Silver Wolf (Adelv Unegv Waya) Phd, Catherine N. Dulmus Phd, Eugene Maguin Phd, Maria Cristalli

Brown School Faculty Publications

Objectives: The existing literature on the impact of workplace conditions on client care suggests that good cultures and climates provide the best outcomes for clients. The primary purpose of this study was to investigate the relationship between organizational culture and climate and the proportion of children and youth successfully discharged from a large organization in New York State. Method: Thirty-three child and youth programs with existing culture and climate data evaluated outcome information from 1,336 clients exiting its services. Results: Programs reported as having bad culture and climate yielded superior client outcomes, measured as discharge to a lower level of …

Abc Agra V. Critical Access Group Appellant's Brief Dckt. 40573

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Validity And Reliability Of Using A Self-Lavaging Device For Cytology And Hpv Testing For Cervical Cancer Screening: Findings From A Pilot Study, Heidi E. Jones, Mahesh M. Mansukhani, Guo-Xia Tong, Carolyn L. Westhoff

Publications and Research

Self-sampling could increase cervical cancer screening uptake. While methods have been identified for human papillomavirus (HPV) testing, to date, self-sampling has not provided adequate specimens for cytology. We piloted the validity and reliability of using a self-lavaging device for cervical cytology and HPV testing. We enrolled 198 women in New York City in 2008–2009 from three ambulatory clinics where they received cervical cancer screening. All were asked to use the Delphi Screener™ to self-lavage 1–3 months after clinician-collected index cytological smear (100 normal; 98 abnormal). Women with abnormal cytology results from either specimen underwent colposcopy; 10 women with normal results …

The Effects Of Acute Post Exercise Consumption Of Two Cocoa-Based Beverages With Varying Flavanol Content On Indices Of Muscle Recovery Following Downhill Treadmill Running, Katelyn Peschek, Robert Pritchett, Ethan Bergman, Kelly Pritchett

All Faculty Scholarship for the College of the Sciences

Dietary flavanols have been associated with reduced oxidative stress, however their efficacy in promoting recovery after exercise induced muscle damage is unclear. This study examined the effectiveness of acute consumption of cocoa-flavanols on indices of muscle recovery including: subsequent exercise performance, creatine kinase, muscle tenderness, force, and self-perceived muscle soreness. Eight endurance-trained athletes (VO2max 64.4 ± 7.6 mL/kg/min) completed a downhill running protocol to induce muscle soreness, and 48-h later completed a 5-K (kilometer) time trial. Muscle recovery measurements were taken at PRE, 24 h-POST, 48 h-POST, and POST-5K. Participants consumed 1.0 g of carbohydrate per kilogram of body weight …

Transvaginal Ultrasonography In Ovarian Cancer Screening: Current Perspectives, John R. Van Nagell Jr., John T. Hoff

Obstetrics and Gynecology Faculty Publications

Transvaginal ultrasonography (TVS) is an integral part of all major ovarian cancer screening trials. TVS is accurate in detecting abnormalities in ovarian volume and morphology, but is less reliable in differentiating benign from malignant ovarian tumors. When used as the only screening test, TVS is sensitive, but has a low positive predictive value. Therefore, serum biomarkers and tumor morphology indexing are used together with TVS to identify ovarian tumors at high risk for malignancy. This allows preoperative triage of high-risk cases to major cancer centers for therapy while decreasing unnecessary surgery for benign disease. Ovarian cancer screening has been associated …

Tennessee Home Visiting Programs Annual Report, July 1, 2012 - June 30, 2013, Tennessee. Department Of Health.

Home Visiting Program Annual Report

No abstract provided.

Techniques For The Visualization Of Positional Geospatial Uncertainty, Brent A. Barré

LSU New Orleans Theses and Dissertations

Geospatial data almost always contains some amount of uncertainty due to inaccuracies in its acquisition and transformation. While the data is commonly visualized (e.g. on digital maps), there are unanswered needs for visualizing uncertainty along with it. Most research on effectively doing this addresses uncertainty in data values at geospatial positions, e.g. water depth, human population, or land-cover classification. Uncertainty in the data’s geospatial positions themselves (positional uncertainty) has not been previously focused on in this regard. In this thesis, techniques were created for visualizing positional uncertainty using World Vector Shoreline as an example dataset. The techniques consist of a …

Hurricane-Exposed Youth And Psychological Distress: An Examination Of The Role Of Social Support, Donice M. Banks

LSU New Orleans Theses and Dissertations

Hurricane exposure places youth at risk for psychological distress such as symptoms of Posttraumatic Stress Disorder (PTSD), anxiety, and depression, while social support may contribute to resilience following disasters. This study examined associations among family and peer social support, level of hurricane exposure, and psychological distress using both a large single-time assessment sample (N = 1098) and a longitudinal sample followed over a six-month period (n = 192). Higher levels of hurricane exposure were related to lower levels of social support from family and peers as well as to higher levels of psychological distress. Higher levels of family …

High Yield Solvothermal Synthesis Of Hexaniobate Based Nanocomposites Via The Capture Of Preformed Nanoparticles In Scrolled Nanosheets, Shivaprasad Reddy Adireddy

LSU New Orleans Theses and Dissertations

The ability to encapsulate linear nanoparticle (NP) chains in scrolled nanosheets is an important advance in the formation of nanocomposites.These nanopeapods (NPPs) exhibit interesting properties that may not be achieved by individual entities. Consequently, to fully exploit the potential of NPPs, the fabrication of NPPs must focus on producing composites with unique combinations of morphologically uniform nanomaterials. Various methods can produce NPPs, but expanding these methods to a wide variety of material combinations can be difficult. Recent work in our group has resulted in the in situ formation of peapod-like structures based on chains of cobalt NPs. Building on this …

Coupling Of The Hpa And Hpg Axes, Andrew Dismukes

LSU New Orleans Theses and Dissertations

The Hypothalamic-Pituitary-Adrenal (HPA) and –Gonadal (HPG) axes have been considered mutually inhibitory; however, emerging evidence supports the proposition that this might not necessarily be the case. This idea is termed “coupling,” in which the HPA-HPG axis are mutually activated or deactivated. Coupling is examined across three data sets with different time-courses of stress exposure, and results demonstrate HPA-HPG co-activation occurs. Furthermore, stress exposure influences this relationship. The discussion shows how it is physiologically possible to have positive coupling or co-activation between these axes according to complex regulatory feedback systems and overlapping neural structures. Findings are interpreted developmentally, because adolescence may …

Experiences And Perceptions Of Novice Associate Degree Nursing Faculty Assuming A Classroom Instructors Role, Mary N. Fontenelle

LSU New Orleans Theses and Dissertations

The purpose of this research was to explore the classroom experiences and perceptions of novice faculty in the classroom setting of an Associate Degree of Nursing programs, located in community colleges. The transition from expert practitioner to novice teacher can be a difficult experience for new classroom nursing instructors. Novice nursing faculty often has very limited educational preparation or background in classroom instruction skills. Nursing research, typically conducted at university level, has minimal applicability for the community college nursing programs. Community colleges educate sixty percent of the graduate Registered Nurses in the United States and have scant research into their …

High Resolution X-Ray Diffraction Analysis Of Cb1 Receptor Antagonists As A Means To Explore Binding Affinity, Steven P. Fournet

LSU New Orleans Theses and Dissertations

Abstract

Charge density studies have been conducted on ten CB₁ cannabinoid receptor antagonists via high resolution x-ray crystallography. Bond critical point values and various other properties derived from these studies including the electrostatic potential were analyzed in correlation to the affinity of each compound with the CB₁ receptor. Correlation/anti-correlation was found between several properties and K_i. The data was also interpreted by principal component analysis with three principal components accounting for 85% of the data variation. Data mining was limit due to the low sample count and the requirements set for the inclusion of correlated/anti-correlated variables …

Transcriptional Co-Repressor Response Of Arabidopsis Thaliana To Different Abiotic Stress, Bhuwan Guragain

LSU New Orleans Theses and Dissertations

Plants adapt to the complex environmental challenges by regulating their gene expression. Analyses of plant genomes have identified many genes that are either expressed or repressed during environmental stress. However we do not have much information on gene repression. Transcriptional repression in Arabidopsis thaliana is caused by co-repressors that lack the DNA binding domain and are recruited by transcription factors to regulate target gene expression. The Sridhar lab has identified co-repressors SLK1, SLK2, and LUH, which prevent the expression of stress response genes under non-stress conditions. Arabidopsis transgenic lines expressing the GUS under the control of co-repressor’s promoter were created, …

Clients' Perceptions Of Their Counseling Experiences For Trauma Related To Anesthesia Awareness (Aa), N. Arlene Magee

LSU New Orleans Theses and Dissertations

Each year in the United States, approximately 81 million individuals receive surgeries in which .1% to .2% (20,000 to 40,000/20 million) experience Anesthesia Awareness (AA). More than 50% of the AA cases result in mental distress or Posttraumatic Stress Disorder (PTSD). Because the percentage of AA cases among surgeries makes it appear to be a rare occurrence, and because it has received rather limited research attention, I decided to undertake an interpretative phenomenological analysis to discover AA clients’ perceptions of their counseling experience, and encourage development of therapeutic interventions to meet their needs.

The broad research question for my study …

Sistas On The Move: An Ethnographic Case Study Of Health And Friendship In Urban Space Among Black Women In New Orleans, Valerie A. Mcmillan

LSU New Orleans Theses and Dissertations

Abstract

Black women are disproportionately affected by adverse health conditions, such as obesity and heart disease. For example, more black women currently die from complications associated with diabetes, obesity and high blood pressure than any other ethnic group in the United States (Gourdine 2011). There are however, increasing numbers of everyday black women who defy these statistics and are positive role models for all women. One such group of women is the New Orleans chapter of Sistas On The Move (SOTM), an all-female running group that emphasizes the importance of black women’s health and builds community around physical activity. Through …

Knights, Dudes, And Shadow Steeds: Late Victorian Culture And The Early Cycling Clubs Of New Orleans, 1881-1891, Lacar E. Musgrove

LSU New Orleans Theses and Dissertations

In the 1880s, two cycling clubs formed in New Orleans—the New Orleans Bicycle Club in 1881 and the Louisiana Cycling Club in 1887. These clubs were institutions of Victorian middle class culture that, like other athletic clubs, arose from the conditions of urban modernity and Victorian class anxieties. The NOBC, like other American cycling clubs, conformed to Victorian values of order and respectability. The attitudes and activities of the LCC, whose membership was younger, reflected instead a counter-Victorian ethos. This paper examines these two clubs in the context of late Victorian culture in New Orleans as it responded both to …

Wastewater Disinfection In Enclosed Recirculation Systems With Electromagnetic Waves, Luis G. Mosquera

LSU New Orleans Theses and Dissertations

Finding the most cost-effective and environmental friendly way to treat and disinfect wastewater has been raising concerns around the world. Failure in performing disinfection of wastewater before returning it to the environment could have terrible consequences to human health and the ecosystem. The risks associated to continue with current practices have led to the creation of stringent regulations.

In this research the HYDROPATH technology is tested while attaching a HydroFlow 60i unit to a reactor that works as a closed recirculation system. To determine the feasibility of the HydroFlow 60i unit as an alternative method to chlorine, the EPA method …