Digital Commons Network^™

The Internationalization Of Creative Professional Service Firms, Deirdre Mcquillan

Doctoral

The need to understand the internationalization process of the organization is a field of increasing contemporary interest due to greatly intensified trade flows between nations over the last two decades. While traditionally internationalization was generally pursued by manufacturing firms, service organizations, including creative professional service firms (creative PSFs) such as architects now commonly internationalize their activities. However, theory to date continues to focus on traditional manufacturing firms, and while insights relating to service firm internationalization have gained traction over the last decade, theoretical contributions remain fragmented and overlook the particular features of how creative PSFs internationalize. This is despite the …

Beginning Farmers: Will They Face Up To Safety And Health Hazards?, Louise Byler, Nancy Ellen Kiernan, Sam Steel, Patricia Neiner, Dennis J. Murphy

Journal of Extension

The study reported here assessed the farm safety and health training needs of beginning farmers in Pennsylvania to help educators develop training workshops and materials to meet those needs. Results of the online survey indicate that participants highly value farm safety, consider themselves to have mostly minimal to moderate skills relative to the safe operation of farms, and are willing to attend safety training workshops. The results of the study provide direction to Extension educators in designing farm safety and health training for this growing constituent group.

Partnering With School Nutrition Professionals To Promote Fruit And Vegetable Intake Through Taste-Testing Activities, Sherri M. Cirignano, Luanne J. Hughes, Corey J. Wu-Jang, Kathleen Morgan, Alexandra Grenci, Leeanne Savoca

Journal of Extension

The Healthy, Hunger-Free Kids Act (HHFKA) of 2010 sets new nutrition standards for schools, requiring them to serve a greater variety and quantity of fruits and vegetables. Extension educators in New Jersey partnered with school nutrition professionals to implement a school wellness initiative that included taste-testing activities to support schools in achieving the milestones established by the HHFKA. Results indicated that "previewing" foods may influence students' interest in, and acceptance of, new foods, opening up outreach and partnership opportunities for Extension educators to consider when working to promote school wellness.

Expanding Cooperative Extension's Audience: Establishing A Relationship With Cowboy Church Members, Katy Williams, Robert Strong, Landry Lockett

Journal of Extension

The study reported here provided a descriptive report on cowboy churches, while identifying the potential for Extension-cowboy church collaborations and examining the direct implications to Extension. The diffusion of innovations conceptualized the qualitative study. Semi-structured, face-to-face and phone interviews were conducted with 10 adults from cowboy churches. Findings revealed relative advantages for Extension-cowboy church collaborations, areas of compatibility, and ample opportunities for trialibility. Disseminating nutrition, animal science, and youth development information to cowboy church members may establish a relationship between the two groups. Extension could gain positive advocates in local communities through educating and establishing relationships with cowboy church members.

From Emotions To Shared Values, David Chan

Research Collection School of Social Sciences

In an invited commentary, SMU director of Behavioural Sciences Institute Professor David Chan noted that although the negative emotions that dominated 2013 have led to some positive outcomes, emotions cannot be the foundation for society’s progress. Professor Chan suggested that, moving forward, Singapore should focus on three shared values (integrity, fairness, social harmony) and three guiding principles (rule of law, accountability, people-centricity).

Between Evangelism And Multiculturalism: The Dynamics Of Christianity In Indonesia, Chang Yau Hoon

Research Collection School of Social Sciences

Christianity has experienced rapid growth in Indonesia, particularly the Evangelical and Pentecostal/Charismatic movements, which find fertile ground among the urban middle class. This phenomenon has given rise to fears of Christianisation among the Muslim majority, who perceive the Christian growth as a moral threat. Tensions between Christians and Muslims have been part and parcel of religious developments in Indonesia. The author addresses the ways in which Protestant churches in Indonesia negotiate between evangelism (to fulfil the ‘Great Commission’) on the one hand, and multiculturalism (peaceful coexistence with difference) on the other. The article will examine how Christians in Indonesia navigate …

Detecting Well-Being Via Computerized Content Analysis Of Brief Diary Entries, William Tov, Kok Leong Ng, Han Lin, Lin Qiu

Research Collection School of Social Sciences

Two studies evaluated the correspondence between self-reported well-being and codings of emotion and life content by the Linguistic Inquiry and Word Count (LIWC; Pennebaker, Booth, & Francis, 2011). Open-ended diary responses were collected from 206 participants daily for 3 weeks (Study 1) and from 139 participants twice a week for 8 weeks (Study 2). LIWC negative emotion consistently correlated with self-reported negative emotion. LIWC positive emotion correlated with self-reported positive emotion in Study 1 but not in Study 2. No correlations were observed with global life satisfaction. Using a co-occurrence coding method to combine LIWC emotion codings with life-content codings, …

Correlation Between Central Corneal Thickness Measurements Using Two Uifferent Ultrasonic Pachymeters, Sharmeen Akram, Zarksis H, Anklesaria A, Khabir Ahmad

Department of Surgery Docs

Purpose: To assess correlation between central corneal thickness measurements using two different ultrasonic pachymeters. Material and Methods: This prospective study involved normal subjects aged 16 to 45 years. Central corneal thickness was measured in 47 eyes by two ultrasonic pachymeters – Tomey SP – 100 and Sonomed 300 AP. Correlations between CCT measurements assessed by the two pachymeters were tested by Pearson correlation. Results: Forty seven eyes were included in the study. The mean (± SD) age of the subjects was 27.79 years (± 6.88).The mean (± SD) Tomey Pachymeter CCT was 536.45 m (34.37) and the mean (SD) Sonomed …

Rna Interference Targeting Glucose-Regulated-Protein 78 Induces Hepg2 Cell Apoptosis, Brittany Blackman

Seton Hall University Dissertations and Theses (ETDs)

Cancer is a complex genetic disease that is driven by genetic mutations resulting in chronic, inappropriate cell proliferation. Many current cancer therapies lack specificity towards tumor tissues, ultimately leading to adverse side effects and limited clinical efficacy. Recently, selective cancer cell therapy has examined a well-characterized cell surface marker that is preferentially expressed on tumor cells. The over-expression of an endoplasmic reticulum chaperone protein, 78-kDa glucose-regulated-protein (GRP78), has been observed on the surface of cancer cells, but not on normal tissues. By selectively targeting GRP78 with short-interfering RNA (siRNA), potent GRP78 silencing is anticipated by the RNA interference (RNAi) pathway. …

Mountain Monitor - 3rd Quarter 2013, Kenan Fikri, Mark Muro

Mountain Monitor Quarterly

The quarter’s Mountain Monitor marks the four-year anniversary of Brookings Mountain West's quarterly tracking of the uneven pace of recovery across the major metro areas of the Intermountain West and it finds that, although the region continues to outperform the national economy the rate of recovery slowed moderately in the region’s metro areas.

As a group, Mountain region metro areas advanced on all four indicators of economic recovery tracked by the Monitor—employment, output, unemployment, and house prices—but their progress was more restrained in the third quarter of 2013 than it was in the second.

Beneath the regional headline of moderating …

Advancing Southern Nevada’S Regional Priorities: Overview Of The 77th Session Of The Nevada Legislature, David F. Damore

Brookings Mountain West Publications

On January 10, 2013 the elected leadership of Southern Nevada met to discuss the region’s governance, K--‐12, higher education, infrastructure, economic development, and health care needs. From that bipartisan discussion emerged policy priorities for the 77^th Session of the Nevada Legislature. This report examines the degree to which the region’s elected senators and assembly members advanced these priorities and represented the interests of Southern Nevada in state government.

The Impact Of The Great Recession On Nevada’S Latino Community, John P. Tuman, David F. Damore, Maria J.F. Agreda

Brookings Mountain West Publications

The emergence of the Great Recession of 2008 had a profound impact in Nevada. The economic downturn generated high unemployment levels and led to turbulence in many sectors, particularly residential home construction and the hospitality industry. In the wake of the crisis, median home prices in Nevada plunged, while the residential foreclosure rate increased and remains one of the highest rates in the country. By 2009, it was evident that a tightening of commercial bank lending for new mortgages, combined with the impact of rising joblessness and plunging housing values, was hampering recovery efforts in the housing sector and Nevada’s …

Low-Cost Scheffler Solar Concentrator For The Developing World, Darren Sholes, Jason Morgan, Nicholas Fuller

Mechanical Engineering

This report will outline an approach to design, test, and build a low-cost Scheffler solar concentrator to be used for safer, sustainable and cost effective cooking in the developing world. The function of Scheffler concentrators and a proposed method to create one in an economic, environmentally conscious manner is summarized. If successful, the design will be presented in a way that is readily and freely available to anyone in the world. The authors have examined existing technology and researched the availability and cost of different materials. Analysis was performed in order to verify the feasibility of the different design ideas …

The Imperative Of Conserving California's Foothill Oak Woodlands, Lauren Phillips

Social Sciences

No abstract provided.

Pedagogical Development Of Zen Buddhism And Taoism For Taos Ed. Ventures, Kelsey Tyler

Social Sciences

Taos Ed. Ventures is an outdoor guiding company that will be offering backpacking trips in Taos, New Mexico to high school and college students, with ages ranging from 16 – 29, starting the summer of 2015. Along with backpacking skills, the philosophies of Zen Buddhism and Taoism will be taught while on the trail. To teach these philosophies, a pedagogy was created, combining aspects of Sentipensante and Contemplative pedagogies that seeks to teach the daily applications of Zen Buddhism and Taoism through experiential and innovative learning methods, such as journaling, meditation, and mindfulness practices. The benefits of these alternative learning …

Health Information And Social Security Entitlements, Perry Singleton

Center for Policy Research

This study examines whether new health information, obtained through medical screening, affects entitlements to Social Security benefits. Random assignment of information is derived from a unique feature of the Continuous National Health and Nutrition Examination Survey. To examine the effect of information on entitlements, the survey data are matched to administrative data from the Social Security Administration. The results suggest that new health information leads to delayed entitlements, particularly among workers near the early retirement age.

A Study On Rebranding Strategies, Megan Bryant

Graphic Communication

This project is a study on rebranding strategies. Companies go through a rebrand to change their strategy and direction. Many companies succeed by going through these processes, while many others fail.

In addition to extensive research on past company rebrands, a questionnaire was conducted on a sample of 25 individuals of various ages about their experiences with brands and rebranding in order to compare their responses with actual company decisions.

Participants provided insight on their own personal behaviors, decisions, and perceptions about brands and purchasing products. The study concluded that, on average, quality was more important than price in almost …

The Effects Of Football Helmet Pressure On The Shock Taken During A Controlled Impact, Sullivan Grosz

Industrial Technology and Packaging

College and NFL football teams are focusing their efforts on protecting players more than ever before. With the recent attention on concussions and the troubling long-term effects of head injuries, more research is needed to find ways to ensure players have the adequate protection. The helmets being used have a hard polycarbonate shell with four inner pads that fit tight to the player’s head. These pads are filled with air.

The purpose of the testing and project is to find an ideal air pressure that helmets need to maintain in order to protect the player to the best of its …

A Phenomenological Study Of Principals Who Transformed A Positive Impact Of School Change, Jason Faklaris

Doctoral Dissertations and Projects

This phenomenological study gathered, examined, and described the knowledge, beliefs, and actions of selected high school principals who had improved student achievement in their schools. This study was conducted to better understand the experience of providing moral leadership in schools, responding to moral challenges within educational settings, and understanding the factors which resulted in the phenomenon of high school principals raising student achievement to consistently meet state requirements. High school principals were selected for participation in the study based on their record of increasing the scores of their students on the Georgia high school graduation test and the Scholastic Aptitude …

Our Dark Places: Questions About Prison Privatization’S Benefit To Louisiana, Christian Hess

Honors Capstones

No abstract provided.

Understanding Urban Education, Emily Watkins

Honors Capstones

No abstract provided.

The Manufacturing Sector In The Greater Northeastern/Northern Region Of Pennsylvania, Ziona Austrian, Candi Clouse, Merissa Piazza, Nikki Glazer, Eunkyu Lee, Hyejin Jung, Eric Esoda

All Maxine Goodman Levin School of Urban Affairs Publications

This report summarizes the findings of an in-depth study of the manufacturing sector in the Greater Northeastern/Northern region of Pennsylvania. The objective of the first section is to draw attention to the role manufacturing plays in the regional economy. It compares manufacturing to other sectors of the economy in terms of employment, gross regional product, wages, productivity, and number of establishments (See Table E-1). It also briefly describes trends in the value of shipments of manufacturing goods as a proxy for exports, manufacturers’ investments in capital expenditures as a measure of capital intensity and adoption of technology, and patenting activity …

Skills Learning In Robot-Assisted Surgery Is Benefited By Task-Specific Augmented Feedback, Srikant Vallabhajosula, Srikant Vallabhajosula, Timothy N. Judkins, Mukul Mukherjee, I. H. Suh, D. Oleynikov, K.-C. Siu

Journal Articles

Background: Providing augmented visual feedback is one way to enhance robot-assisted surgery (RAS) training. However, it is unclear whether task specificity should be considered when applying augmented visual feedback. Methods: Twenty-two novice users of the da Vinci Surgical System underwent testing and training in 3 tasks: simple task, bimanual carrying (BC); intermediate task, needle passing (NP); and complex task, suture tying (ST). Pretraining (PRE), training, and posttraining (POST) trials were performed during the first session. Retention trials were performed 2 weeks later (RET). Participants were randomly assigned to 1 of 4 feedback training groups: relative phase (RP), speed, grip force, …

Novel Functions Of Cetuximab In Egfr-Targeted Therapy: Radiosensitization, Glycolysis Inhibition, And Cellular Redox Status Regulation, Haiquan Lu

Dissertations and Theses (Open Access)

Epidermal growth factor receptor (EGFR) is overexpressed in the majority of head and neck cancers. The anti-EGFR antibody cetuximab has been approved by the FDA for the treatment of head and neck cancers, however, only a small fraction of patients respond to cetuximab treatment. Further investigation to understand the mechanisms underlying cetuximab-mediated EGFR-targeted therapy and to develop novel therapeutic strategies to improve the efficacy of cetuximab is urgently needed. In the present study, we elucidated the mechanism of cetuximab in radiosensitization, and discovered novel functions of cetuximab in glycolysis inhibition and cellular redox status regulation. We found that cetuximab inhibits …

An Evaluation Of The Consistency Of Imrt Patient-Specific Qa Techniques, Elizabeth M. Mckenzie

Dissertations and Theses (Open Access)

To ensure the integrity of an intensity modulated radiation therapy (IMRT) treatment, each plan must be validated through a measurement-based quality assurance (QA) procedure, known as patient specific IMRT QA. Many methods of measurement and analysis have evolved for this QA. There is not a standard among clinical institutions, and many devices and action levels are used. Since the acceptance criteria determines if the dosimetric tools’ output passes the patient plan, it is important to see how these parameters influence the performance of the QA device. While analyzing the results of IMRT QA, it is important to understand the variability …

Ezh2 T416 Phosphorylation Enhances Breast Cancer Tumorigenesis, Adam M. Labaff, Adam M. Labaff

Dissertations and Theses (Open Access)

Enhancer of zeste homologue 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 (PRC2) and catalyzes the trimethylation of histone H3 on lysine 27 (H3K27Me3), to repress gene transcription. Many types of cancer stem and progenitor cells, including breast, have demonstrated EZH2 to be fundamental in the biology and promoting the expansion of their cellular populations. How EZH2 regulates each of these respective tumor initiating cells (TICs) populations has been studied, but the signaling transduction mechanisms that regulate EZH2 in these TIC populations is yet to be elucidated. Phosphorylation of EZH2 by cyclin dependent kinases (CDK) has been …

Characterization Of Oslds For Use In Small Field Photon Beam Dosimetry, Christopher Pham

Dissertations and Theses (Open Access)

The goal of this study was to redesign a Radiological Physics Center (RPC) mailable remote audit tool used for stereotactic radiosurgery (SRS) single beam dosimetry. A prototype phantom was designed and built housing nanoDot (Landauer Inc., Glenwood, IL) Al₂O₃:C optically stimulated luminescence dosimeters (OSLDs) whose visible active luminescent area has been masked. The phantom has two measurement points with two OSLDs at each location and a film insert for localization purposes only. The masked OSLDs were characterized accounting for various correction factors associated with OSLD dose calculations. The uncertainties for each correction factor were also investigated. …

Developmental And Molecular Functions Of Plakophilin-3, William A. Munoz

Dissertations and Theses (Open Access)

Plakophilin-3, the less studied member of the plakophilin-catenin subfamily, and the larger catenin family, binds directly to desmosomal cadherin cytoplasmic domains and enhances desmosome formation and stability. In mammals, plakophilin-3 is expressed at the highest levels in desmosome-enriched tissues such as epithelia, with the knock-out in mice producing corresponding reductions in ectodermal integrity. In tissue, cellular and intracellular contexts where plakophilin-3 is not at the desmosomal plaque, little is known about its functions in the cytoplasm or nucleus, where it also localizes.

My work employed embryos of the amphibian, Xenopus laevis, to examine plakophilin-3’s developmental roles. I first evaluated …

Investigation Of Respiratory Motion Management Techniques For Proton And Photon Radiotherapy Of Lung Cancer, Jason E. Matney

Dissertations and Theses (Open Access)

Protons as a source of therapeutic radiation can provide a substantial improvement over dose distributions that can be achieved with conventional sources of radiation such as high-energy photons. However, respiratory motion can significantly impact the delivered proton and photon dose distributions during lung cancer radiotherapy. The goals of this dissertation research were to evaluate the impact of respiratory motion and to estimate the benefit of respiratory gating for passively scattered proton therapy (PSPT) and intensity modulated photon therapy (IMRT).

The first aim of this project was to determine the impact of respiratory motion in PSPT and IMRT. Four dimensional dose …

The Role And Mechanism Of The Homeobox Gene Hoxa9 In The Growth Of Epithelial Ovarian Cancer, Song Yi Ko

Dissertations and Theses (Open Access)

Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer death among women in the United States. The high lethality of EOCs stems from rapid peritoneal involvement. EOCs frequently colonize peritoneal surfaces that overlie connective and adipose tissues. However, the mechanisms that enable ovarian cancer cells to readily adapt to the peritoneal environment are poorly understood. HOXA9, a homeobox gene that is normally expressed in the developing female reproductive tract, is aberrantly expressed in EOCs and controls the morphologic features of these tumors. The differentiation pattern of a tumor is an important determinant of its clinical behavior and …