Digital Commons Network^™

Inhibitory Effect Of Il-17 On Neural Stem Cell Proliferation And Neural Cell Differentiation., Zichen Li, Ke Li, Lin Zhu, Quancheng Kan, Yaping Yan, Priyanka Kumar, Hui Xu, Abdolmohamad Rostami, Guang-Xian Zhang

Department of Neurology Faculty Papers

BACKGROUND: IL-17, a Th17 cell-derived proinflammatory molecule, has been found to play an important role in the pathogenesis of autoimmune diseases, including multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). While IL-17 receptor (IL-17R) is expressed in many immune-related cells, microglia, and astrocytes, it is not known whether IL-17 exerts a direct effect on neural stem cells (NSCs) and oligodendrocytes, thus inducing inflammatory demyelination in the central nervous system.

METHODS: We first detected IL-17 receptor expression in NSCs with immunostaining and real time PCR. We then cultured NSCs with IL-17 and determined NSC proliferation by neurosphere formation …

What Are The Characteristics That Explain Hospital Quality? A Longitudinal Pridit Approach, Robert D. Lieberthal, Dominique M. Comer

College of Population Health Faculty Papers

Health outcomes vary substantially between high and low quality institutions, meaning the difference between life and death in some cases. Prior literature has identified a number of variables that can be used to determine hospital quality, but methodologies for combining variables into an overall measure of hospital quality are not well developed. This analysis builds on the prior investigation of hospital quality by evaluating a method originally developed for the detection of healthcare fraud, Pridit, in the context of determining hospital quality. We developed a theoretical model to justify the application of Pridit to the hospital quality setting and then …

Micro-Symposium On Orin Kerr's 'A Theory Of Law', Laura Appleman, Shawn Bayern, Adam D. Chandler, Robert Cheren, Miriam A. Cherry, Ross E. Davies, Lee Anne Fennell, Paul A. Gowder, Caitlin Hartsell, Kieran Healy, Robert A. James, Jeffrey H. Kahn, Orin S. Kerr, Jacob T. Levy, Jeffrey M. Lipshaw, Orly Lobel, Geoffrey A. Manne, Chad M. Oldfather, Ronak Patel, Jeffrey A. Pojanowski, Alexandra J. Roberts, Kent Scheidegger, Arthur Stock, Anders Walker

All Faculty Scholarship

For more than a century, careful readers of the Green Bag have known that “[t]here is nothing sacred in a theory of law...which has outlived its usefulness or which was radically wrong from the beginning...The question is What is the law and what is the true public policy?” Professor Orin Kerr bravely, creatively, and eloquently answered that question in his article, “A Theory of Law,” in the Autumn 2012 issue of the Green Bag. Uniquely among all theories of law that I know of, Kerr’s answer to the fundamental question of law and true public policy enables all scholars to …

Ethical Issues In Faith-Based Ngos: A Cross Cultural Perspective, Annetta M. Gibson, Charles H. Tidwell Jr.

Andrews University Seminary Studies (AUSS)

No abstract provided.

Review Of John H. Walton's Genesis 1 As Ancient Cosmology, Jacques B. Doukhan

Andrews University Seminary Studies (AUSS)

No abstract provided.

Novum Testamentum Graece: Nestle-Aland, 28th Ed. [Review] / Institute For New Testament Textual Research, Carl P. Cosaert

Andrews University Seminary Studies (AUSS)

No abstract provided.

Seventh-Day Adventist, Semi-Pelagiansim, And Overlooked Topics In Adventist Soteriology: Moving Beyond Missing Links And Toward A More Explicit Understanding, George R. Knight

Andrews University Seminary Studies (AUSS)

No abstract provided.

Flying Bishops, Women Clergy, And The Processes Of Change In The Anglican Communion, Gilbert M. Valentine

Andrews University Seminary Studies (AUSS)

No abstract provided.

The Remnant Concept In Early Adventism: From Apocalyptic Antisectarianism To An Eschatological Denominational Ecclesiology, Stefan Höschele

Andrews University Seminary Studies (AUSS)

No abstract provided.

Theological Contributions Of John Wesley To The Doctrine Of Perfection, Theodore N. Levterov

Andrews University Seminary Studies (AUSS)

No abstract provided.