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Articles 2281 - 2310 of 35627
Full-Text Articles in Entire DC Network
Evolution Of The Pygmy Phenotype: Evidence Of Positive Selection From Genome-Wide Scans In African, Asian, And Melanesian Pygmies, Andrea Bamberg Migliano, Irene Gallego Romero, Mait Metspalu, Matthew Leavesley, Luca Pagani, Tiago Antao, Da-Wei Huang, Brad T. Sherman, Katharine Siddle, Clarissa Scholes, Georgi Hudjashov, Elton Kaitokai, Avis Babalu, Maggie Belatti, Alex Cagan, Bryony Hopkinshaw, Colin Shaw, Mari Nelis, Ene Metspalu, Reedik Mägi, Richard A. Lempicki, Richard Villems, Marta Mirazon Lahr, Toomis Kivisild
Evolution Of The Pygmy Phenotype: Evidence Of Positive Selection From Genome-Wide Scans In African, Asian, And Melanesian Pygmies, Andrea Bamberg Migliano, Irene Gallego Romero, Mait Metspalu, Matthew Leavesley, Luca Pagani, Tiago Antao, Da-Wei Huang, Brad T. Sherman, Katharine Siddle, Clarissa Scholes, Georgi Hudjashov, Elton Kaitokai, Avis Babalu, Maggie Belatti, Alex Cagan, Bryony Hopkinshaw, Colin Shaw, Mari Nelis, Ene Metspalu, Reedik Mägi, Richard A. Lempicki, Richard Villems, Marta Mirazon Lahr, Toomis Kivisild
Human Biology
Human pygmy populations inhabit different regions of the world, from Africa to Melanesia. In Asia, short-statured populations are often referred to as "negritos." Their short stature has been interpreted as a consequence of thermoregulatory, nutritional, and/or locomotory adaptations to life in tropical forests. A more recent hypothesis proposes that their stature is the outcome of a life history trade-off in high-mortality environments, where early reproduction is favored and, consequently, early sexual maturation and early growth cessation have coevolved. Some serological evidence of deficiencies in the growth hormone/insulin-like growth factor axis have been previously associated with pygmies’ short stature. Using genome-wide …
Admixture Patterns And Genetic Differentiation In Negrito Groups From West Malaysia Estimated From Genome-Wide Snp Data, Timothy A. Jinam, Maude E. Phipps, Naruya Saitou, The Hugo Pan-Asian Snp Consortium
Admixture Patterns And Genetic Differentiation In Negrito Groups From West Malaysia Estimated From Genome-Wide Snp Data, Timothy A. Jinam, Maude E. Phipps, Naruya Saitou, The Hugo Pan-Asian Snp Consortium
Human Biology
Southeast Asia houses various culturally and linguistically diverse ethnic groups. In Malaysia, where the Malay, Chinese, and Indian ethnic groups form the majority, there exist minority groups such as the "negritos" who are believed to be descendants of the earliest settlers of Southeast Asia. Here we report patterns of genetic substructure and admixture in two Malaysian negrito populations (Jehai and Kensiu), using ~50,000 genome-wide single-nucleotide polymorphism (SNP) data. We found traces of recent admixture in both the negrito populations, particularly in the Jehai, with the Malay through principal component analysis and STRUCTURE analysis software, which suggested that the admixture was …
Climate Change Influenced Female Population Sizes Through Time Across The Indonesian Archipelago, Elsa G. Guillot, Meryanne K. Tumonggor, Stephen J. Lansing, Herawati Sudoyo, Murray P. Cox
Climate Change Influenced Female Population Sizes Through Time Across The Indonesian Archipelago, Elsa G. Guillot, Meryanne K. Tumonggor, Stephen J. Lansing, Herawati Sudoyo, Murray P. Cox
Human Biology
Lying at the crossroads of Asia and the Pacific world, the Indonesian archipelago hosts one of the world’s richest accumulations of cultural, linguistic, and genetic variation. While the role of human migration into and around the archipelago is now known in some detail, other aspects of Indonesia’s complex history are less understood. Here, we focus on population size changes from the first settlement of Indonesia nearly 50 kya up to the historic era. We reconstructed the past effective population sizes of Indonesian women using mitochondrial DNA sequences from 2,104 individuals in 55 village communities on four islands spanning the Indonesian …
The Skeletal Phenotype Of "Negritos" From The Andaman Islands And Philippines Relative To Global Variation Among Hunter-Gatherers, Jay T. Stock
Human Biology
The "negrito hypothesis" suggests that populations of small-bodied foragers in South and Southeast Asia who share common phenotypic characteristics may also share a common, ancient origin. The key defining characteristics of the "negrito" phenotype, small body size, dark skin, and tightly curled hair, have been interpreted as linking these populations to sub-Saharan Africans. The underlying assumption of this interpretation is that the observed phenotypic similarities likely reflect shared ancestry rather than phenotypic convergence. Current genetic evidence is inconclusive, as it both demonstrates that negrito populations have genetic affinities with neighboring populations but also rare and ancient variation that suggests considerable …
Hunter-Gatherers In Southeast Asia: From Prehistory To The Present, Charles Higham
Hunter-Gatherers In Southeast Asia: From Prehistory To The Present, Charles Higham
Human Biology
Anatomically modern hunter-gatherers expanded from Africa into Southeast Asia at least 50,000 years ago, where they probably encountered and interacted with populations of Homo erectus and Homo floresiensis and the recently discovered Denisovans. Simulation studies suggest that these hunter-gatherers may well have followed a coastal route that ultimately led to the settlement of Sahul, while archaeology confirms that they also crossed significant seas and explored well into the interior. They also adapted to marked environmental changes that alternated between relatively cool and dry conditions and warmer, wetter interludes. During the former, the sea fell by up to 120 m below …
Introduction: Revisiting The "Negrito" Hypothesis: A Transdisciplinary Approach To Human Prehistory In Southeast Asia, Phillip Endicott
Introduction: Revisiting The "Negrito" Hypothesis: A Transdisciplinary Approach To Human Prehistory In Southeast Asia, Phillip Endicott
Human Biology
The "negrito" hypothesis predicts that a shared phenotype among various contemporary groups of hunter-gatherers in Southeast Asia - dark skin, short stature, tight curly hair - is due to common descent from a region-wide, pre-Neolithic substrate of humanity. The alternative is that their distinctive phenotype results from convergent evolution. The core issues of the negrito hypothesis are today more relevant than ever to studies of human evolution, including the out-of-Africa migration, admixture with Denisovans, and the effects of environment and ecology on life-history traits. Understanding the current distribution of the negrito phenotype dictates a wide-ranging remit for study, including the …
Washington Update: News From Our Nation's Capital, Sherine B. Abdul-Khaliq, Jit Chatterjee, Chandana Kolavala, Rebecca Wolf
Washington Update: News From Our Nation's Capital, Sherine B. Abdul-Khaliq, Jit Chatterjee, Chandana Kolavala, Rebecca Wolf
Health Law and Policy Brief
No abstract provided.
The Erisa Roadblock: Can States Overcome Erisa Preemption And Enact Meaningful Health Care Reforms, Sabrina Dunlap
The Erisa Roadblock: Can States Overcome Erisa Preemption And Enact Meaningful Health Care Reforms, Sabrina Dunlap
Health Law and Policy Brief
No abstract provided.
The Legal And Moral Implications Of Growth Attenuation, Meryl Eschen Mills
The Legal And Moral Implications Of Growth Attenuation, Meryl Eschen Mills
Health Law and Policy Brief
No abstract provided.
Crossing Borders: An Interdisciplinary Course In The "Enlightenment", Carol White, Kathryn P. Russell
Crossing Borders: An Interdisciplinary Course In The "Enlightenment", Carol White, Kathryn P. Russell
ABO: Interactive Journal for Women in the Arts, 1640–1830
In this essay, we present a twofold version of the first team-taught course on the eighteenth century designed by faculty at Clayton State University who plan to develop and teach this course again in the near future. We hope that our explanation of the original course and our projected future version of the course will be useful to scholars who teach in the eighteenth century, as well as to specialists in other historical periods who wish to plan revisions of courses to make them more reflective of current scholarship in gender studies. Authors taught in this course include Benjamin Franklin, …
Determination Of The Permeability Of The South Chamorro Seamount In Mariana Forearc Crust Using Pressure Response To Tidal Loading Method, Putri Nur El Akmal
Determination Of The Permeability Of The South Chamorro Seamount In Mariana Forearc Crust Using Pressure Response To Tidal Loading Method, Putri Nur El Akmal
Open Access Theses
ODP borehole observatory 1200C, drilled into the South Chamorro seamount and instrumented with Circulation Obviation Retrofit Kit (CORK), provided information about natural fluid pressure within this forearc crust. The seafloor and formation pressure data recorded hourly and shown fluctuations that are caused largely by the ocean tides. The data also shown two transient pressures increase at the time of two earthquakes. Harmonic analysis provides a simpler way to analyze the periodic tidal signals that constitute the pressure records. By using the result of the harmonic analysis and applying simple theory of formation response to tidal loading, developed by Wang & …
Stress And Reproductive Hormones In Grizzly Bears Reflect Nutritional Benefits And Social Consequences Of A Salmon Foraging Niche, Heather M. Bryan, Chris T. Darimont, Paul C. Paquet, Katherine E. Wynne-Edwards, Judit E. G. Smits
Stress And Reproductive Hormones In Grizzly Bears Reflect Nutritional Benefits And Social Consequences Of A Salmon Foraging Niche, Heather M. Bryan, Chris T. Darimont, Paul C. Paquet, Katherine E. Wynne-Edwards, Judit E. G. Smits
Physiology Collection
Physiological indicators of social and nutritional stress can provide insight into the responses of species to changes in food availability. In coastal British Columbia, Canada, grizzly bears evolved with spawning salmon as an abundant but spatially and temporally constrained food source. Recent and dramatic declines in salmon might have negative consequences on bear health and ultimately fitness. To examine broadly the chronic endocrine effects of a salmon niche, we compared cortisol, progesterone, and testosterone levels in hair from salmon-eating bears from coastal BC (n = 75) with the levels in a reference population from interior BC lacking access to salmon …
Taylor V. Riley Appellant's Reply Brief Dckt. 40599
Taylor V. Riley Appellant's Reply Brief Dckt. 40599
Idaho Supreme Court Records & Briefs, All
No abstract provided.
The Guardian, November 27, 2013, Wright State University Student Body
The Guardian, November 27, 2013, Wright State University Student Body
The Guardian Student Newspaper
Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.
The Relationship Of Sex And Sexual Orientation To Self-Esteem, Body Shape Satisfaction, And Eating Disorder Symptomatology, Chetra Yaan, Erik M. Benau, Antonios Dakanalis, Julia M. Hormes, Julie Perone, C. Alix Timko
The Relationship Of Sex And Sexual Orientation To Self-Esteem, Body Shape Satisfaction, And Eating Disorder Symptomatology, Chetra Yaan, Erik M. Benau, Antonios Dakanalis, Julia M. Hormes, Julie Perone, C. Alix Timko
Counseling & Psychological Services
No abstract provided.
Out Of Information Poverty: Library Services For Urban Marginalized Immigrants, Lan Shen
Out Of Information Poverty: Library Services For Urban Marginalized Immigrants, Lan Shen
Urban Library Journal
This paper provides an analytical overview of the literature on information poverty and the strategies of reducing such poverty for urban marginalized groups from cultural and structural perspectives. Focusing on the urban immigrants in the United States, this paper discusses their informational needs with respect to literacy skills, technology support, cultural awareness, and information resources. In addition, the paper evaluates the library services demonstrated by the selected urban libraries that supply diversified education programs and civic engagement activities in an attempt to establish a more equitable and harmonious community.
Digital Inclusion, Learning, And Access At The Public Library, Melissa Morrone, Shanelle Witt
Digital Inclusion, Learning, And Access At The Public Library, Melissa Morrone, Shanelle Witt
Urban Library Journal
New York City is not an easy place to live. Brooklynites who are just learning about the Internet in 2013—20 years after the development of the World Wide Web—likely have more challenges than simply needing someone to show them how to open up the computer's browser. Brooklyn Public Library has been engaged in a digital inclusion project that brings together issues of ability, access, and learning styles. By giving our patrons skills and confidence to navigate technology both online and off, we are laying the groundwork for them to have a voice in the city.
Summary Of Clay V. Eighth Jud. Dist. Ct., 129 Nev. Adv. Op. 91, Joseph Peacock
Summary Of Clay V. Eighth Jud. Dist. Ct., 129 Nev. Adv. Op. 91, Joseph Peacock
Nevada Supreme Court Summaries
The Court determined one issue: whether NRS 62H.170(2)(c) or NRS 62H.170(3) permits the State to inspect a defendant’s sealed juvenile record to obtain information for use against that defendant in a subsequent criminal prosecution.
Boyd-Davis V. Baker Appellant's Brief Dckt. 40438
Boyd-Davis V. Baker Appellant's Brief Dckt. 40438
Idaho Supreme Court Records & Briefs, All
No abstract provided.
State V. Elias Appellant's Brief Dckt. 41477
State V. Elias Appellant's Brief Dckt. 41477
Idaho Supreme Court Records & Briefs, All
No abstract provided.
Johnson V. State Clerk's Record V. 2 Dckt. 41414
Johnson V. State Clerk's Record V. 2 Dckt. 41414
Idaho Supreme Court Records & Briefs, All
No abstract provided.
Regan V. Owen Appellant's Reply Brief Dckt. 40848
Regan V. Owen Appellant's Reply Brief Dckt. 40848
Idaho Supreme Court Records & Briefs, All
No abstract provided.
Library As Scholarly Publishing Partner: Keys To Success, Gordon Mcintyre, Janice Chan, Julia Gross
Library As Scholarly Publishing Partner: Keys To Success, Gordon Mcintyre, Janice Chan, Julia Gross
Research outputs 2013
Many academic libraries are looking at new ways to add value when they deliver services to faculty, and one potential area where the library can provide new services is in partnering with academic staff to support the dissemination of faculty research. Librarians have traditionally helped faculty researchers at the beginning of the research cycle, with the discovery and delivery of information sources. However, they are now playing a role at the end of the research cycle, providing services that support scholarly publishing. This paper examines library participation in faculty-led publishing ventures. In particular, it explores the value that smaller research …
A Cell Permeable Peptide Targeting The Intracellular Loop 2 Of Endothelin B Receptor Reduces Pulmonary Hypertension In A Hypoxic Rat Model, Daniel S. Green, Chamila Rupasinghe, Rod Warburton, Jamie L. Wilson, Christine O. Sallum, Linda Taylor, Achan Yatawara, Dale Mierke, Peter Polgar, Nicholas Hill
A Cell Permeable Peptide Targeting The Intracellular Loop 2 Of Endothelin B Receptor Reduces Pulmonary Hypertension In A Hypoxic Rat Model, Daniel S. Green, Chamila Rupasinghe, Rod Warburton, Jamie L. Wilson, Christine O. Sallum, Linda Taylor, Achan Yatawara, Dale Mierke, Peter Polgar, Nicholas Hill
Dartmouth Scholarship
Cell permeable peptides (CPP) aid cellular uptake of targeted cargo across the hydrophobic plasma membrane. CPP-mediated cargo delivery of receptor signaling motifs provides an opportunity to regulate specific receptor initiated signaling cascades. Both endothelin-1 receptors, ETA and ETB, have been targets of antagonist therapies for individuals with pulmonary arterial hypertension (PAH). These therapies have had success but have been accompanied by adverse reactions. Also, unlike the CPP which target specific signaling cascades, the antagonists target the entire function of the receptor. Using the CPP strategy of biased antagonism of the ETB receptor’s intracellular loop 2 (ICB2), we demonstrate blunting of …
Dispatches From The Trenches Of America's Great Gun Trust Wars, Lee-Ford Tritt
Dispatches From The Trenches Of America's Great Gun Trust Wars, Lee-Ford Tritt
NULR Online
No abstract provided.
Gerdon V. State Respondent's Brief Dckt. 40454
Correction: Association Of Pol Diversity With Antiretroviral Atment Outcomes Among Hiv-Infected African Children, Iris Chen, Leila Khaki, Jane C. Lindsey, Carrie Fry, Matthew M. Cousins, Robert F. Siliciano, Avy Violari, Paul Palumbo, Susan H. Eshleman
Correction: Association Of Pol Diversity With Antiretroviral Atment Outcomes Among Hiv-Infected African Children, Iris Chen, Leila Khaki, Jane C. Lindsey, Carrie Fry, Matthew M. Cousins, Robert F. Siliciano, Avy Violari, Paul Palumbo, Susan H. Eshleman
Dartmouth Scholarship
Background: In HIV-infected children, viral diversity tends to increase with age in the absence of antiretroviral treatment (ART). We measured HIV diversity in African children (ages 6–36 months) enrolled in a randomized clinical trial comparing two ART regimens (Cohort I of the P1060 trial). Children in this cohort were exposed to single dose nevirapine (sdNVP) at birth. Methods: HIV diversity was measured retrospectively using a high resolution melting (HRM) diversity assay. Samples were obtained from 139 children at the enrollment visit prior to ART initiation. Six regions of the HIV genome were analyzed: two in gag , one in pol …
State V. Pendergrass Appellant's Reply Brief Dckt. 40914
State V. Pendergrass Appellant's Reply Brief Dckt. 40914
Not Reported
No abstract provided.
E-Book Adoption In Academic & Research Libraries: Self Reported Information Behaviour, Pervaiz Ahmad
E-Book Adoption In Academic & Research Libraries: Self Reported Information Behaviour, Pervaiz Ahmad
InfoSci@ECU Seminars
No abstract provided.