Digital Commons Network^™

T-Cell Dependent Immunogenicity Of Protein Therapeutics: Preclinical Assessment And Mitigation, Vibha Jawa, Leslie P. Cousens, Michel Awwad, Eric Wakshull, Harald Kropshofer, Anne S. De Groot

Institute for Immunology and Informatics Faculty Publications

Protein therapeutics hold a prominent and rapidly expanding place among medicinal products. Purified blood products, recombinant cytokines, growth factors, enzyme replacement factors, monoclonal antibodies, fusion proteins, and chimeric fusion proteins are all examples of therapeutic proteins that have been developed in the past few decades and approved for use in the treatment of human disease. Despite early belief that the fully human nature of these proteins would represent a significant advantage, adverse effects associated with immune responses to some biologic therapies have become a topic of some concern. As a result, drug developers are devising strategies to assess immune responses …

Perfect Snapping: An Accurate And Efficient Interactive Image Segmentation Algorithm, Qingsong Zhu, Guanzheng Liu, Zhanyong Mei, Qi Li, Yaoqin Xie, Lei Wang

Applied Mathematics & Information Sciences

Interactive image segmentation is a process that extracts a foreground object from an image based on limited user input. In this paper, we propose a novel interactive image segmentation algorithm named Perfect Snapping which is inspired by the presented method named Lazy Snapping technique. In the algorithm, the mean shift algorithm with a boundary confidence prior is introduced to efficiently pre-segment the original image into homogeneous regions (super-pixels) with precise boundary. Secondly, GaussianMixture Model (GMM) clustering algorithm is used to describe and to model the super-pixels. Finally, a Monte Carlo based Expectation Maximization (EM) algorithm is used to perform parametric …

Real-Time Subsurface Scattering For Particle-Based Fluids Using Finite Volume Method, Kyung-Kyu Kang, Dongho Kim

Applied Mathematics & Information Sciences

We present a real-time subsurface scattering simulation to perform real-time rendering of translucent particle-based fluids. After particle-based fluid simulation, we immediately build voxelized fluids, called Voronoi fluids, with particle locations and neighbour lists using GPUs. And then, we perform a multiple subsurface scattering simulation over the Voronoi fluids with the diffusion equation (DE). We employ Finite Volume Methods to solve DE efficiently and rapidly with the voxelized fluids. In our implementation, DE is solved on GPUs with the diffusive source boundary condition and query function for computing the outgoing radiance.We demonstrate a milk demo that show our method can be …

The Advocate Summer 2013, University Of Tennessee College Of Law

The Advocate

No abstract provided.

College Connections Newsletter, Summer 2013, Jeanne Curran-Sarto (Ed.)

CAHS College Connections Newsletter

In this issue:

• Our Newest Distinguished Professor
• Music Professor Wins 2 Awards
• A Student Accomplishment
• Pulled from the Earth

Faulker, Ervena, Ervena Faulker, Portia Morgan, David Slutzky

Video Collection

No abstract provided.

Martin, Deborah, Deborah Martin, Debbie Frost

Video Collection

No abstract provided.

Heyward, Leon, Leon Heyward, Ishmael Lewis, Deborah Oden

Video Collection

No abstract provided.

Petal, Sarah Marshall

Harpur Palate: a Literary Journal

Pages 66-78

Vol. 5, Issue 2

Library Newsletter (2009-present)

Beijing Qingming Scroll

Personal Librarian Program

Hangin’ With Henry…

The fabulous Touch Screen Scanner is Back!

A Revolving Display of Stimulating Resources

Bryant DVD Drive

Laptop Central Relocates!

Look What’s NEW in Reference

Bryant Student Centers Past and Present

Look Who’s Summering in Bello

Humor In The Classroom: A Series Of Three Workshop Plans, Roger Ramirez

MA TESOL Collection

This materials development project explores the role, use and forms of humor in the classroom. This IPP is a collection of a series of three workshop plans for ELT teacher trainers located in Latin America. The workshop plans are preceded by a rationale that explains the relevancy of the topic, the author’s personal belief statement, and an exploration of final key learnings from developing this project. Each workshop plan is followed by a reflection on aspects that went well along with suggestions for further improvement and a revised version of the workshop plan.

The I5k Initiative: Advancing Arthropod Genomics For Knowledge, Human Health, Agriculture, And The Environment, I5k Consortium, Marian Goldsmith

Biological Sciences Faculty Publications

Insects and their arthropod relatives including mites, spiders, and crustaceans play major roles in the world’s terrestrial, aquatic, and marine ecosystems. Arthropods compete with humans for food and transmit devastating diseases. They also comprise the most diverse and successful branch of metazoan evolution, with millions of extant species. Here, we describe an international effort to guide arthropod genomic efforts, from species prioritization to methodology and informatics. The 5000 arthropod genomes initiative (i5K) community met formally in 2012 to discuss a roadmap for sequencing and analyzing 5000 high-priority arthropods and is continuing this effort via pilot projects, the development of standard …

Wsu Research News, Spring/Summer 2013, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

A twenty page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

Liberalis, Summer 2013, Utah State University

Liberalis

Freedom to Think, Discover, and Create. The alumni magazine for the College of Humanities and Social Sciences at Utah State University.

Creating The Ideal Co-Teaching Inclusion Classroom, Sarah Stanfar

Education 589 Projects

No abstract provided.

Guadalupe Avalos - Filling Caskets More Quickly Than Cribs?: A Comparison Of Infant Mortality In Milwaukee And Costa Rica, Guadalupe Avalos

Ronald E. McNair Scholars Program 2013

Metropolitan Milwaukee had infant mortality rates at 9.5 deaths per 1,000 live births in 2010, according to the Milwaukee Health Department. This rate is a reversal of earlier decades. Between 2005 and 2008, Milwaukee experienced its highest infant mortality rate at 11 deaths per 1,000 live births. Disparities are most evident between African-Americans and Whites. Therefore, most explanations of infant mortality rates are compared between the two backgrounds. Since 2008, infant mortality rates have dwindled; however, the rates remain unacceptably high. A rate of 9.5 deaths per live births is detrimental and a public health issue.

By analyzing causes that …

Oxidative Stress Disruption Of Receptor-Mediated Calcium Signaling Mechanisms, Tso-Hao Tang, Chiung-Tan Chang, Hsiu-Jen Wang, Joshua Erickson, Rhett A. Reichard, Alexis Martin, Erica Shannon, Adam L. Martin, Yue-Wern Huang, Robert Aronstam

Biological Sciences Faculty Research & Creative Works

Background: Oxidative stress increases the cytosolic content of calcium in the cytoplasm through a combination of effects on calcium pumps, exchangers, channels and binding proteins. In this study, oxidative stress was produced by exposure to tert-butyl hydroperoxide (tBHP); cell viability was assessed using a dye reduction assay; receptor binding was characterized using [³H]N-methylscopolamine ([³H]MS); and cytosolic and luminal endoplasmic reticulum (ER) calcium concentrations ([Ca²⁺]_i and [Ca²⁺]_L, respectively) were measured by fluorescent imaging.

Results: Activation of M3 muscarinic receptors induced a biphasic increase in [Ca²⁺] …

Goldfield Studies, Dawn Roe

Faculty Publications

The dialogue within this essay serves as a response to the series, Goldfield Studies, a work itself prompted by the history and landscape of this eponymous region of Victoria, Australia. The imagery produced takes the form of paired and multiple still photographs and a digital video sequence, displayed in triple-projection. The discussion is framed by the artist’s introduction, which defines the project as a critical consideration of cultural memory in relation to the opposing perspectives of indigenous and colonial settler narratives, pastoral landscape representations, folklore and myth. A collaborative dialogue between an artist and art historian who share common research …

Southern Register. 2013.3 (Summer 2013), University Of Mississippi. Center For The Study Of Southern Culture

Southern Register

No abstract provided.

Genesis 12-50 And Work, Theology Of Work Project, Bob Stallman

Theology of Work Project

1. Introduction to Genesis 12-50 and Work
2. Abraham (Genesis 12:1-25:11)
   • Abraham’s faithfulness contrasted with the faithlessness of Babel (Genesis 12:1-3)
   • The Pastoral Lifestyle of Abraham and his Family (Genesis 12:4-7)
   • Abraham’s journey begins with disaster in Egypt (Genesis 12:8-13:2)
   • Abraham and Lot parted (Genesis 13:3-18)
   • Abraham and Sarah’s hospitality (Genesis 18:1-15)
   • Abraham’s dispute with Abimelech (Genesis 20:1-16; 21:22-34)
   • A burial plot for Sarah (Genesis 23:1-20)
3. Isaac (Genesis 21:1-35:29)
4. Jacob (Genesis 25:19-49:33)
   • Jacob's unethical procurement of Esau’s birthright and blessing (Genesis 25:19-34; 26:34–28:9)
   • Jacob Gains His Fortune (Genesis 30-31)
   • Jacob’s transformation and reconciliation with Esau (Genesis 32–33)
5. Joseph (Genesis 37:2-50:26)
   • Joseph rejected …

Alcohol In The Life Narratives Of Women: Commonalities And Differences By Sexual Orientation, Laurie A. Drabble, K. Trocki

Faculty Publications

Aim: The aim of this study was to explore social representations of alcohol use among women, with a focus on possible differences between sexual minority and heterosexual women. Methods: This qualitative study was part of a larger study examining mediators of heavier drinking among sexual minority women (lesbian identified, bisexual identified, and heterosexual identified with same sex partners) compared to heterosexual women based on the National Alcohol Survey. Qualitative in-depth life history interviews were conducted over the telephone with 48 women who had participated in the 2009–2010 National Alcohol Survey, including respondents representing different sexual orientation groups. Questions explored the …

Camas, Summer 2013

Camas

Waiting / Rick Bass -- The Cakewalk / Jenner Harsha -- Nurse Log / Mark Rozema -- Water Contours / Denise Fisher -- Oil Baby / Carl Corder -- Coming to Rest / Emily Strauss -- Lines on the Land / Emily Strauss -- What We Talk About When We Talk About the Weather / Matthew Burns -- Such Grim Seasons / Mercedes Lawry -- 279 / Clark Chatlain -- 316 / Clark Chatlain -- Benchmark / Jolie B. Kaytes -- Scratch Gravel / Kira Knoles

El Haikú Del Lavabo, Eleftherios Makedonas

Hipertexto

No abstract provided.

An Economic Survey Analysis Of The Legal Literature Pertaining To The Privacy Implications Of Radio Frequency Identification Technology, Stephen M. Jerbic

Faculty Publications

No abstract provided.

Decades-Long Social Memory In Bottlenose Dolphins, Jason N. Bruck

Faculty Publications

Long-term social memory is important, because it is an ecologically relevant test of cognitive capacity, it helps us understand which social relationships are remembered and it relates two seemingly disparate disciplines: cognition and sociality. For dolphins, long-term memory for conspecifics could help assess social threats as well as potential social or hunting alliances in a very fluid and complex fission-fusion social system, yet we have no idea how long dolphins can remember each other. Through a playback study conducted within a multi-institution dolphin breeding consortium (where animals are moved between different facilities), recognition of unfamiliar versus familiar signature whistles of …

Moulinet: An Action Quarterly, Volume 14, Issues 2 & 3, Moulinet Staff

Moulinet: An Action Quarterly

No abstract provided.

Alumni Newsletter July 2013, Communications Disorders & Sciences

Newsletters and Documents

No abstract provided.

Examining Historical (Mis)Representations Of Christopher Columbus Within Children’S Literature, John H. Bickford

Faculty Research and Creative Activity

Effective teaching, while supplemented by best practice methods and assessments, is rooted in accurate, age-appropriate, and engaging content. As a foundation for history content, elementary educators rely strongly on textbooks and children’s literature, both fiction and non-fiction. While many researchers have examined the historical accuracy of textbook content, few have rigorously scrutinized the historical accuracy of children’s literature. Those projects that carried out such examination were more descriptive than comprehensive due to significantly smaller data pools. I investigate how children’s non-fiction and fiction books depict and historicize a meaningful and frequently taught history topic: Christopher Columbus’s accomplishments and misdeeds. Results …

Abortion And Disgust, Courtney Megan Cahill

Scholarly Publications

This Article uses disgust theory — defined as the insights on disgust by psychologists and social scientists — to critique disgust’s role in abortion lawmaking. Its starting point is a series of developments that independently highlight and call into question the relationship between abortion and disgust. First, the Supreme Court introduced disgust as a valid basis for abortion regulation in its 2007 case Gonzales v. Carhart. Second, psychologists have recently discovered a sufficiently strong association between individual disgust sensitivity and abortion opposition to suggest that disgust might drive that opposition. They have also discovered that “abortion disgust” appears to be …

God's Farm, Lawrence Campbell

Harpur Palate: a Literary Journal

Pages 24-26