Digital Commons Network^™

A Presence Of The Past: The Legal Protection Of Singapore’S Archaeological Heritage, Jack Tsen-Ta Lee

Research Collection Yong Pung How School Of Law

Singapore is not well known for its archaeological heritage. In fact, chance finds in the early 20th century and systematic archaeological excavations since the 1980s conducted at sites around the Singapore River have unearthed artefacts shedding light on the island’s early history. In addition, the value of archaeology for a deeper knowledge of Singapore’s British colonial past is increasingly being recognized. Nonetheless, Singapore law provides only a rudimentary framework to facilitate archaeological investigations and protect cultural artefacts. This article considers how the National Heritage Board Act (Cap 196A, 1994 Rev Ed), the Planning Act (Cap 232, 1998 Rev Ed), and …

Animal Protection Laws Of Singapore And Malaysia, Alvin W. L. See

Research Collection Yong Pung How School Of Law

This article offers an overview and assessment of the laws relating to the protection of animals in Singapore and Malaysia. The focus is on identifying the interpretations of the statutory offences of cruelty that will best promote their objectives and effectiveness.

Embodied Conflict Resolution: Resurrecting Roleplay-Based Curricula Through Dance, Nadja Alexander, Michelle Lebaron

Research Collection Yong Pung How School Of Law

Moving on from the authors’ seminal 2009 critique of the overuse of role-plays in negotiation teaching, "Death of the Role-Play" (chapter 13 in Rethinking Negotiation Teaching), Alexander and LeBaron have taken the rapidly increasing enthusiasm for experiential learning in a new direction: multiple intelligences. Their particular interest is in a use of experiential learning that focuses on kinesthetic intelligence, employing actual physical movement, particularly dance, to unlock creativity in other mental domains, as well as to encourage authentic participation by people whose skills are not primarily verbal or mathematical. Those who may be inclined to be skeptical should note that …

A Mesh Generation And Machine Learning Framework For Drosophila Gene Expression Pattern Image Analysis, Wenlu Zhang, Daming Feng, Rongjian Li, Andrey Chernikov, Nikos Chrisochoides, Christopher Osgood, Charlotte Konikoff, Stuart Newfeld, Sudhir Kumar, Shuiwang Ji

Computer Science Faculty Publications

Background: Multicellular organisms consist of cells of many different types that are established during development. Each type of cell is characterized by the unique combination of expressed gene products as a result of spatiotemporal gene regulation. Currently, a fundamental challenge in regulatory biology is to elucidate the gene expression controls that generate the complex body plans during development. Recent advances in high-throughput biotechnologies have generated spatiotemporal expression patterns for thousands of genes in the model organism fruit fly Drosophila melanogaster. Existing qualitative methods enhanced by a quantitative analysis based on computational tools we present in this paper would provide …

Assessing Connections Between Young Children’S Affinity For Nature And Their Experiences In Natural Outdoor Settings In Preschools, Camilla S. Rice, Julia C. Torquati

Department of Child, Youth, and Family Studies: Faculty Publications

The purposes of this research were to: develop a reliable measure of children’s affinity for nature or “biophilia”; determine whether young children’s biophilia was related to the “green-ness” of the outdoor play area of the preschool they attend; examine whether demographic variables are associated with children’s biophilia; and determine whether demographic variables predict children’s enrollment in nature-oriented programs. We recruited children from ten early childhood education programs—six that had outdoor play spaces with many natural elements and four that had few or none of these elements. One hundred fourteen preschool-aged children completed an 11-item measure of biophilia that included preferences …

Beyond The Walls: Conceptualizing Natural Environments As “Third Educators”, Julia C. Torquati, Julie A. Ernst

Department of Child, Youth, and Family Studies: Faculty Publications

This research examined preservice early childhood educators’ perceptions of outdoor settings and their intentions to use outdoor settings in their teaching practice. Students enrolled in an early childhood education program (n = 110) at a university in the Great Lakes region completed surveys that assessed perceptions of natural settings, intentions to use natural settings in future teaching, knowledge of the benefits of nature for children, and personal nature relatedness. Participants reported relatively high intentions to use natural settings in future teaching, as well as knowledge of the benefits of nature for children, but moderate levels of personal nature relatedness. Participants …

Using Technology To Support Individuals With Asd: A Review Of The Literature, Katherine Anoyiannakis

Honors Projects

No abstract provided.

Factors Influencing Local Recruitment In Tree Swallows, Tachycineta Bicolor, Danielle M. Andrews

Honors Projects

We extensively monitored the nests of Tree Swallows (Tachycineta bicolor) at 100 nest boxes every day during each breeding season from 1992 to 2006. The birds were banded and recorded as a means to track those who returned as recruits. We identified 166 recruits; the sex ratio of recruits was not significantly different from 50:50 and the distribution of recruits between nests was no different than expected by chance. We calculated a local recruitment rate of 4.79% when considering all nestlings (N=3463). We found a significant difference between brood size at hatching categories (1-3, 4, 5, 6, 7-8) and whether …

Towards A Consensus View On Understanding Nanomaterials Hazards And Managing Exposure: Knowledge Gaps And Recommendations, G Hunt, I Lynch, F Cassee, Rd Handy, Tf Fernandes, M Berges, Taj Kuhlbusch, M Dusinska, M Riediker

School of Biological and Marine Sciences

No abstract provided.

Critical Comparison Of Intravenous Injection Of Tio2 Nanoparticles With Waterborne And Dietary Exposures Concludes Minimal Environmentally-Relevant Toxicity In Juvenile Rainbow Trout Oncorhynchus Mykiss., D Boyle, Ga Al-Bairuty, Tb Henry, Rd Handy

School of Biological and Marine Sciences

A critical comparison of studies that have investigated tissue accumulation and toxicity of TiO2-NPs in fish is necessary to resolve inconsistencies. The present study used identical TiO2-NPs, toxicological endpoints, and fish (juvenile rainbow trout Oncorhynchus mykiss) as previous studies that investigated waterborne and dietary toxicity of TiO2-NPs, and conducted a critical comparison of results after intravenous caudal-vein injection of 50 μg of TiO2-NPs and bulk TiO2. Injected TiO2-NPs accumulated only in kidney (94% of measured Ti) and to a lesser extent in spleen; and injected bulk TiO2 was found only in kidney. No toxicity of TiO2 was observed in kidney, …

Towards Improved Socio-Economic Assessments Of Ocean Acidification's Impacts, Nathalie Hilmi, Denis Allemand, Sam Dupont, Alain Safa, Gunnar Haraldsson, Paulo A.L.D. Nunes, Chris Moore, Caroline Hattam, Stéphanie Reynaud, Jason M. Hall-Spencer, Maoz Fine, Carol Turley, Ross Jeffree, James Orr, Philip L. Munday, Sarah R. Cooley

School of Biological and Marine Sciences

No abstract provided.

Our Place In The World: A New Relationship For Environmental Ethics And Law, Jedediah Purdy

Duke Law Journal

Forty years ago, at the birth of environmental law, both legal and philosophical luminaries assumed that the new field would be closely connected with environmental ethics. Instead, the two grew dramatically apart. This Article diagnoses that divorce and proposes a rapprochement. Environmental law has always grown through changes in public values; for this and other reasons, it cannot do so without ethics. Law and ethics are most relevant to each other when there are large open questions in environmental politics: lawmakers act only when some ethical clarity arises; but law can itself assist in that ethical development. This process is …

Effects Of Local And Landscape Processes On Animal Distribution And Abundance, Aaron David Flesch

Graduate Student Theses, Dissertations, & Professional Papers

Investigations of processes that drive animal distribution and abundance are often approached at one of two different scales and therefore focus on different processes. At local scales, animals are thought to select home ranges or territory patches in an ideal manner by occupying them in order of their fitness potential, but a variety of processes can decouple choices from their fitness consequences and create non-ideal patterns of distribution. At landscape scales, the spatial arrangement of habitat patches and their size and isolation are thought to influence distribution patterns because extinction probability declines with increasing patch area and colonization probability declines …

Bow Lake, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Chocorua Lake, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Goose Pond, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Great East Lake, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Lake Kanasatka, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Lake Wentworth, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Mendums Pond, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Newfound Lake, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Silver Lake, Madison, Cooperative Extension

UNH Cooperative Extension

No abstract provided.

Gamma Oscillatory Amplitude Encodes Stimulus Intensity In Primary Somatosensory Cortex, Holly E. Rossiter, Sian F. Worthen, Caroline Witton, Stephen D. Hall, Paul L. Furlong

School of Psychology

No abstract provided.

Opportunities And Constraints To Community Forest User Groups Participating In Redd+ Payment Programs In Nepal, Alexander Cuthbert Smith

Graduate Student Theses, Dissertations, & Professional Papers

In response to global concern for the consequences of climate change, the United Nations’ Reducing Emissions from Deforestation and Forest Degradation (REDD+) program was developed to support greenhouse gas emission reduction and carbon sequestration in developing countries. While still being developed around the world, in Nepal a REDD+ pilot project is being conducted with the involvement of the Nepali government’s Department of Forestry (DoF) and its community forestry program. The pilot project is called “REDD+ in Community Managed Forests in Nepal” (RCMFN). The commitment of Nepal’s government to carry out this project makes it an ideal location to study carbon …

Ethanol Diverts Early Neuronal Differentiation Trajectory Of Embryonic Stem Cells By Disrupting The Balance Of Lineage Specifiers., Rosa Sánchez-Alvarez, Saurabh Gayen, Rajanikanth Vadigepalli, Helen Anni

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Ethanol is a toxin responsible for the neurodevelopmental deficits of Fetal Alcohol Spectrum Disorders (FASD). Recent evidence suggests that ethanol modulates the protein expression of lineage specifier transcription factors Oct4 (Pou5f1) and Sox2 in early stages of mouse embryonic stem (ES) cell differentiation. We hypothesized that ethanol induced an imbalance in the expression of Oct4 and Sox2 in early differentiation, that dysregulated the expression of associated and target genes and signaling molecules and diverted cells from neuroectodermal (NE) formation.

METHODOLOGY/PRINCIPAL FINDINGS: We showed modulation by ethanol of 33 genes during ES cell differentiation, using high throughput microfluidic dynamic array …

Cis And Trans Regulatory Mechanisms Control Ap2-Mediated B Cell Receptor Endocytosis Via Select Tyrosine-Based Motifs., Kathleen Busman-Sahay, Lisa Drake, Anand Sitaram, Michael Marks, James R Drake

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Following antigen recognition, B cell receptor (BCR)-mediated endocytosis is the first step of antigen processing and presentation to CD4+ T cells, a crucial component of the initiation and control of the humoral immune response. Despite this, the molecular mechanism of BCR internalization is poorly understood. Recently, studies of activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) have shown that mutations within the BCR subunit CD79b leads to increased BCR surface expression, suggesting that CD79b may control BCR internalization. Adaptor protein 2 (AP2) is the major mediator of receptor endocytosis via clathrin-coated pits. The BCR contains five putative AP2-binding …

The Contributions Of Hif-Target Genes To Tumor Growth In Rcc., Ting Zhang, Xiaohua Niu, Lili Liao, Eun-Ah Cho, Haifeng Yang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Somatic mutations or loss of expression of tumor suppressor VHL happen in the vast majority of clear cell Renal Cell Carcinoma, and it's causal for kidney cancer development. Without VHL, constitutively active transcription factor HIF is strongly oncogenic and is essential for tumor growth. However, the contribution of individual HIF-responsive genes to tumor growth is not well understood. In this study we examined the contribution of important HIF-responsive genes such as VEGF, CCND1, ANGPTL4, EGLN3, ENO2, GLUT1 and IGFBP3 to tumor growth in a xenograft model using immune-compromised nude mice. We found that the suppression of VEGF or CCND1 impaired …

Chronic Ethanol Feeding Alters Mirna Expression Dynamics During Liver Regeneration., Rachael P Dippold, Rajanikanth Vadigepalli, Gregory E. Gonye, Biswanath Patra, Jan B. Hoek

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Adaptation to chronic ethanol (EtOH) treatment of rats results in a changed functional state of the liver and greatly inhibits its regenerative ability, which may contribute to the progression of alcoholic liver disease.

METHODS: In this study, we investigated the effect of chronic EtOH intake on hepatic microRNA (miRNA) expression in male Sprague-Dawley rats during the initial 24 hours of liver regeneration following 70% partial hepatectomy (PHx) using miRNA microarrays. miRNA expression during adaptation to EtOH was investigated using RT-qPCR. Nuclear factor kappa B (NFκB) binding at target miRNA promoters was investigated with chromatin immunoprecipitation.

RESULTS: Unsupervised clustering of …

Is The Reporting Timeliness Gap For Avian Flu And H1n1 Outbreaks In Global Health Surveillance Systems Associated With Country Transparency?, Feng-Jen Tsai, Eva Tseng, Chang-Chuan Chan, Hiko Tamashiro, Sandrine Motamed, André C Rougemont

Division of Internal Medicine Faculty Papers & Presentations

BACKGROUND: This study aims to evaluate the length of time elapsed between reports of the same incidents related to avian flu and H1N1 outbreaks published by the WHO and ProMED-mail, the two major global health surveillance systems, before and after the amendment of the International Health Regulations in 2005 (IHR 2005) and to explore the association between country transparency and this timeliness gap.

METHODS: We recorded the initial release dates of each report related to avian flu or H1N1 listed on the WHO Disease Outbreak News site and the matching outbreak report from ProMED-mail, a non-governmental program for monitoring emerging …

Factors Shaping The Ontogeny Of Vocal Signals In A Wild Parrot, Karl S. Berg, Steven R. Beissinger, Jack W. Bradbury

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Parrots rely heavily on vocal signals to maintain their social and mobile lifestyles. We studied vocal ontogeny in nests of wild green-rumped parrotlets (Forpus passerinus) in Venezuela. We identified three successive phases of vocal signaling that corresponded closely to three independently derived phases of physiological development. For each ontogenetic phase, we characterized the relative importance of anatomical constraints, motor skills necessary for responding to specific contexts of the immediate environment, and the learning of signals that are necessary for adult forms of communication. We observed shifts in the relative importance of these three factors as individuals progressed from …