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Articles 18331 - 18360 of 19503
Full-Text Articles in Entire DC Network
Hdl And Glut1 Inhibition Reverse A Hypermetabolic State In Mouse Models Of Myeloproliferative Disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet
Hdl And Glut1 Inhibition Reverse A Hypermetabolic State In Mouse Models Of Myeloproliferative Disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet
Open Access Publications
A high metabolic rate in myeloproliferative disorders is a common complication of neoplasms, but the underlying mechanisms are incompletely understood. Using three different mouse models of myeloproliferative disorders, including mice with defective cholesterol efflux pathways and two models based on expression of human leukemia disease alleles, we uncovered a mechanism by which proliferating and inflammatory myeloid cells take up and oxidize glucose during the feeding period, contributing to energy dissipation and subsequent loss of adipose mass. In vivo, lentiviral inhibition of Glut1 by shRNA prevented myeloproliferation and adipose tissue loss in mice with defective cholesterol efflux pathway in leukocytes. Thus, …
Lncipedia: A Database For Annotated Human Lncrna Transcript Sequences And Structures, Pieter-Jan Volders, Kenny Helsens, Xiaowei Wang, Bjorn Menten, Lennart Martens, Kris Gevaert, Jo Vandesompele, Pieter Mestdagh
Lncipedia: A Database For Annotated Human Lncrna Transcript Sequences And Structures, Pieter-Jan Volders, Kenny Helsens, Xiaowei Wang, Bjorn Menten, Lennart Martens, Kris Gevaert, Jo Vandesompele, Pieter Mestdagh
Open Access Publications
No abstract provided.
Molecular Insight Into The Association Between Cartilage Regeneration And Ear Wound Healing In Genetic Mouse Models: Targeting New Genes In Regeneration, Muhammad Farooq Rai, Eric J. Schmidt, Audrey Mcalinden, James M. Cheverud, Linda J. Sandell
Molecular Insight Into The Association Between Cartilage Regeneration And Ear Wound Healing In Genetic Mouse Models: Targeting New Genes In Regeneration, Muhammad Farooq Rai, Eric J. Schmidt, Audrey Mcalinden, James M. Cheverud, Linda J. Sandell
Open Access Publications
No abstract provided.
Cd2ap Links Cortactin And Capping Protein At The Cell Periphery To Facilitate Formation Of Lamellipodia, Jianping Zhao, Serawit Bruck, Saso Cemerski, Lei Zhang, Boyd Butler, Adish Dani, John A. Cooper, Andrey S. Shaw
Cd2ap Links Cortactin And Capping Protein At The Cell Periphery To Facilitate Formation Of Lamellipodia, Jianping Zhao, Serawit Bruck, Saso Cemerski, Lei Zhang, Boyd Butler, Adish Dani, John A. Cooper, Andrey S. Shaw
Open Access Publications
Understanding the physiology of complex relationships between components of signaling pathways and the actin cytoskeleton is an important challenge. CD2AP is a membrane scaffold protein implicated in a variety of physiological and disease processes. The physiological function of CD2AP is unclear, but its biochemical interactions suggest that it has a role in dynamic actin assembly. Here, we report that CD2AP functions to facilitate the recruitment of actin capping protein (CP) to the Src kinase substrate, cortactin, at the cell periphery, and that this is necessary for formation of the short branched filaments that characterize lamellipodium formation and are required for …
Investigation Of Neovascularization In Three-Dimensional Porous Scaffolds In Vivo By A Combination Of Multiscale Photoacoustic Microscopy And Optical Coherence Tomography, Xin Cai, Yu Zhang, Li Li, Sung-Wook Choi, Matthew R. Macewan, Junjie Yao, Chulhong Kim, Younan Xia, Lihong V. Wang
Investigation Of Neovascularization In Three-Dimensional Porous Scaffolds In Vivo By A Combination Of Multiscale Photoacoustic Microscopy And Optical Coherence Tomography, Xin Cai, Yu Zhang, Li Li, Sung-Wook Choi, Matthew R. Macewan, Junjie Yao, Chulhong Kim, Younan Xia, Lihong V. Wang
Open Access Publications
No abstract provided.
Gene-Alcohol Interactions Identify Several Novel Blood Pressure Loci Including A Promising Locus Near Slc16a9, Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao
Gene-Alcohol Interactions Identify Several Novel Blood Pressure Loci Including A Promising Locus Near Slc16a9, Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao
Open Access Publications
No abstract provided.
Oct4/Sox2 Binding Sites Contribute To Maintaining Hypomethylation Of The Maternal Igf2/H19 Imprinting Control Region, David L. Zimmerman, Craig S. Boddy, Christopher S. Schoenherr
Oct4/Sox2 Binding Sites Contribute To Maintaining Hypomethylation Of The Maternal Igf2/H19 Imprinting Control Region, David L. Zimmerman, Craig S. Boddy, Christopher S. Schoenherr
Open Access Publications
No abstract provided.
Brain Mapping In A Patient With Congenital Blindness – A Case For Multimodal Approaches, Jared L. Roland, Carl D. Hacker, Jonathan D. Breshears, Charles M. Gaona, R. Edward Hogan, Harold Burton, Maurizio Corbetta, Eric C. Leuthardt
Brain Mapping In A Patient With Congenital Blindness – A Case For Multimodal Approaches, Jared L. Roland, Carl D. Hacker, Jonathan D. Breshears, Charles M. Gaona, R. Edward Hogan, Harold Burton, Maurizio Corbetta, Eric C. Leuthardt
Open Access Publications
No abstract provided.
Age-Related Vulnerability In The Neural Systems Supporting Semantic Processing, Jonathan E. Peelle, Keerthi Chandrasekaran, John Powers, Edward E. Smith, Murray Grossman
Age-Related Vulnerability In The Neural Systems Supporting Semantic Processing, Jonathan E. Peelle, Keerthi Chandrasekaran, John Powers, Edward E. Smith, Murray Grossman
Open Access Publications
No abstract provided.
Changes In Auditory Perceptions And Cortex Resulting From Hearing Recovery After Extended Congenital Unilateral Hearing Loss, Jill B. Firszt, Ruth M. Reeder, Timothy A. Holden, Harold Burton, Richard A. Chole
Changes In Auditory Perceptions And Cortex Resulting From Hearing Recovery After Extended Congenital Unilateral Hearing Loss, Jill B. Firszt, Ruth M. Reeder, Timothy A. Holden, Harold Burton, Richard A. Chole
Open Access Publications
No abstract provided.
Normal Cognition In Transgenic Bri2-Aβ Mice, Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W. Dickson, David R. Borchelt, Todd Golde, Christopher Janus
Normal Cognition In Transgenic Bri2-Aβ Mice, Jungsu Kim, Paramita Chakrabarty, Amanda Hanna, Amelia March, Dennis W. Dickson, David R. Borchelt, Todd Golde, Christopher Janus
Open Access Publications
No abstract provided.
Timps Of Parasitic Helminths – A Large-Scale Analysis Of High-Throughput Sequence Datasets, Cinzia Cantacessi, Andreas Hofmann, Darren Pickering, Severine Navarro, Makedonka Mitreva, Alex Loukas
Timps Of Parasitic Helminths – A Large-Scale Analysis Of High-Throughput Sequence Datasets, Cinzia Cantacessi, Andreas Hofmann, Darren Pickering, Severine Navarro, Makedonka Mitreva, Alex Loukas
Open Access Publications
No abstract provided.
Phenotypic Characteristics Of Early Wolfram Syndrome, Bess A. Marshall, M. Alan Permutt, Alexander R. Paciorkowski, James Hoekel, Roanne Karzon, Jon Wasson, Amy Viehover, Neil H. White, Joshua S. Shimony, Linda Manwaring, Paul Austin, Timothy E. Hullar, Tamara Hershey, Washington University Wolfram Study Group
Phenotypic Characteristics Of Early Wolfram Syndrome, Bess A. Marshall, M. Alan Permutt, Alexander R. Paciorkowski, James Hoekel, Roanne Karzon, Jon Wasson, Amy Viehover, Neil H. White, Joshua S. Shimony, Linda Manwaring, Paul Austin, Timothy E. Hullar, Tamara Hershey, Washington University Wolfram Study Group
Open Access Publications
No abstract provided.
Ion Permeabilities In Mouse Sperm Reveal An External Trigger For Slo3-Dependent Hyperpolarization, Julio C. Chavez, Jose L. De La Vega-Beltran, Jessica Escoffier, Pablo E. Visconti, Claudia L. Trevino, Alberto Darszon, Lawrence Salkoff, Celia M. Santi
Ion Permeabilities In Mouse Sperm Reveal An External Trigger For Slo3-Dependent Hyperpolarization, Julio C. Chavez, Jose L. De La Vega-Beltran, Jessica Escoffier, Pablo E. Visconti, Claudia L. Trevino, Alberto Darszon, Lawrence Salkoff, Celia M. Santi
Open Access Publications
No abstract provided.
Rapamycin Attenuates The Development Of Posttraumatic Epilepsy In A Mouse Model Of Traumatic Brain Injury, Dongjun Guo, Linghui Zeng, David L. Brody, Michael Wong
Rapamycin Attenuates The Development Of Posttraumatic Epilepsy In A Mouse Model Of Traumatic Brain Injury, Dongjun Guo, Linghui Zeng, David L. Brody, Michael Wong
Open Access Publications
No abstract provided.
Proteomic Analysis Of Oesophagostomum Dentatum (Nematoda) During Larval Transition, And The Effects Of Hydrolase Inhibitors On Development, Martina Ondrovics, Katja Silbermayr, Makedonka Mitreva, Neil D. Young, Ebrahim Razzazi-Fazeli, Robin B. Gasser, Anja Joachim
Proteomic Analysis Of Oesophagostomum Dentatum (Nematoda) During Larval Transition, And The Effects Of Hydrolase Inhibitors On Development, Martina Ondrovics, Katja Silbermayr, Makedonka Mitreva, Neil D. Young, Ebrahim Razzazi-Fazeli, Robin B. Gasser, Anja Joachim
Open Access Publications
No abstract provided.
Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways And Maintains Beta-Cell Phenotype In Human Islets, Nidhi Rohatgi, Haytham Aly, Connie A. Marshall, William G. Mcdonald, Rolf F. Kletzien, Jerry R. Colca, Michael L. Mcdaniel
Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways And Maintains Beta-Cell Phenotype In Human Islets, Nidhi Rohatgi, Haytham Aly, Connie A. Marshall, William G. Mcdonald, Rolf F. Kletzien, Jerry R. Colca, Michael L. Mcdaniel
Open Access Publications
No abstract provided.
Guanylate-Binding Protein 1 (Gbp1) Contributes To Cell-Autonomous Immunity Against Toxoplasma Gondii, Elizabeth M. Selleck, Sarah J. Fentress, Wandy L. Beatty, Daniel Degrandi, Klaus Pfeffer, Herbert W. Virgin Iv, John D. Macmicking, L. David Sibley
Guanylate-Binding Protein 1 (Gbp1) Contributes To Cell-Autonomous Immunity Against Toxoplasma Gondii, Elizabeth M. Selleck, Sarah J. Fentress, Wandy L. Beatty, Daniel Degrandi, Klaus Pfeffer, Herbert W. Virgin Iv, John D. Macmicking, L. David Sibley
Open Access Publications
No abstract provided.
Identification Of A Mitochondrial Target Of Thiazolidinedione Insulin Sensitizers (Mtot)— Relationship To Newly Identified Mitochondrial Pyruvate Carrier Proteins, Patrick A. Vigueira, Brian N. Finck, Et Al
Identification Of A Mitochondrial Target Of Thiazolidinedione Insulin Sensitizers (Mtot)— Relationship To Newly Identified Mitochondrial Pyruvate Carrier Proteins, Patrick A. Vigueira, Brian N. Finck, Et Al
Open Access Publications
No abstract provided.
A Multicenter, Prospective Study Of A New Fully Covered Expandable Metal Biliary Stent For The Palliative Treatment Of Malignant Bile Duct Obstruction, Bert T. Petersen, Michel Kahaleh, Richard A. Kozarek, David Loren, Kapil Gupta, Thomas Kowalski, Martin Freeman, Yang K. Chen, Malcolm S. Branch, Steven Edmundowicz, Michael Gluck, Kenneth Binmoeller, Todd H. Baron, Raj J. Shah, Timothy Kinney, William Ross, Paul Jowell, David Carr-Locke
A Multicenter, Prospective Study Of A New Fully Covered Expandable Metal Biliary Stent For The Palliative Treatment Of Malignant Bile Duct Obstruction, Bert T. Petersen, Michel Kahaleh, Richard A. Kozarek, David Loren, Kapil Gupta, Thomas Kowalski, Martin Freeman, Yang K. Chen, Malcolm S. Branch, Steven Edmundowicz, Michael Gluck, Kenneth Binmoeller, Todd H. Baron, Raj J. Shah, Timothy Kinney, William Ross, Paul Jowell, David Carr-Locke
Open Access Publications
No abstract provided.
Alcohol-Induced Apoptosis Of Oligodendrocytes In The Fetal Macaque Brain, Catherine E. Creeley, Krikor T. Dikranian, Stephen A. Johnson, Nuri B. Farber, John W. Olney
Alcohol-Induced Apoptosis Of Oligodendrocytes In The Fetal Macaque Brain, Catherine E. Creeley, Krikor T. Dikranian, Stephen A. Johnson, Nuri B. Farber, John W. Olney
Open Access Publications
No abstract provided.
Ttm-1 Encodes Cdf Transporters That Excrete Zinc From Intestinal Cells Of C. Elegans And Act In A Parallel Negative Feedback Circuit That Promotes Homeostasis, Hyun Cheol Roh, Sara Collier, Krupa Deshmukh, James Guthrie, David Robertson, Kerry Kornfeld
Ttm-1 Encodes Cdf Transporters That Excrete Zinc From Intestinal Cells Of C. Elegans And Act In A Parallel Negative Feedback Circuit That Promotes Homeostasis, Hyun Cheol Roh, Sara Collier, Krupa Deshmukh, James Guthrie, David Robertson, Kerry Kornfeld
Open Access Publications
No abstract provided.
Myocardial Ablation Of G Protein–Coupled Receptor Kinase 2 (Grk2) Decreases Ischemia/Reperfusion Injury Through An Anti-Intrinsic Apoptotic Pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn Ii, Walter J. Koch, Erhe Gao
Myocardial Ablation Of G Protein–Coupled Receptor Kinase 2 (Grk2) Decreases Ischemia/Reperfusion Injury Through An Anti-Intrinsic Apoptotic Pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn Ii, Walter J. Koch, Erhe Gao
Open Access Publications
No abstract provided.
Motivational Disturbances And Effects Of L-Dopa Administration In Neurofibromatosis-1 Model Mice, David F. Wozniak, Kelly A. Diggs-Andrews, Sara Conyers, Carla M. Yuede, Joshua T. Dearborn, Jacquelyn A. Brown, Kazuhiro Tokuda, Yukitoshi Izumi, Charles F. Zorumski, David H. Gutmann
Motivational Disturbances And Effects Of L-Dopa Administration In Neurofibromatosis-1 Model Mice, David F. Wozniak, Kelly A. Diggs-Andrews, Sara Conyers, Carla M. Yuede, Joshua T. Dearborn, Jacquelyn A. Brown, Kazuhiro Tokuda, Yukitoshi Izumi, Charles F. Zorumski, David H. Gutmann
Open Access Publications
No abstract provided.
In Vivo Visualization Of Notch1 Proteolysis Reveals The Heterogeneity Of Notch1 Signaling Activity In The Mouse Cochlea, Zhiyong Liu, Zhenyi Liu, Bradley J. Walters, Thomas Owen, Raphael Kopan, Jian Zuo
In Vivo Visualization Of Notch1 Proteolysis Reveals The Heterogeneity Of Notch1 Signaling Activity In The Mouse Cochlea, Zhiyong Liu, Zhenyi Liu, Bradley J. Walters, Thomas Owen, Raphael Kopan, Jian Zuo
Open Access Publications
No abstract provided.
Deficiency Of Leishmania Phosphoglycans Influences The Magnitude But Does Not Affect The Quality Of Secondary (Memory) Anti-Leishmania Immunity, Dong Liu, Ifeoma Okwor, Zhirong Mou, Stephen M. Beverley, Jude E. Uzonna
Deficiency Of Leishmania Phosphoglycans Influences The Magnitude But Does Not Affect The Quality Of Secondary (Memory) Anti-Leishmania Immunity, Dong Liu, Ifeoma Okwor, Zhirong Mou, Stephen M. Beverley, Jude E. Uzonna
Open Access Publications
No abstract provided.
Germinal Center B-Cells Resist Transformation By Kras Independently Of Tumor Suppressor Arf, Chelsea D. Mullins, Mack Y. Su, Vishwanathan Hucthagowder, Liang Chu, Lan Lu, Shashikant Kulkarni, Deborah Novack, Ravi Vij, Michael H. Tomasson
Germinal Center B-Cells Resist Transformation By Kras Independently Of Tumor Suppressor Arf, Chelsea D. Mullins, Mack Y. Su, Vishwanathan Hucthagowder, Liang Chu, Lan Lu, Shashikant Kulkarni, Deborah Novack, Ravi Vij, Michael H. Tomasson
Open Access Publications
No abstract provided.
Bcl11a Controls Flt3 Expression In Early Hematopoietic Progenitors And Is Required For Pdc Development In Vivo, Xiaodi Wu, Ansuman T. Satpathy, Wumesh Kc, Pentao Liu, Theresa L. Murphy, Kenneth M. Murphy
Bcl11a Controls Flt3 Expression In Early Hematopoietic Progenitors And Is Required For Pdc Development In Vivo, Xiaodi Wu, Ansuman T. Satpathy, Wumesh Kc, Pentao Liu, Theresa L. Murphy, Kenneth M. Murphy
Open Access Publications
No abstract provided.
Antibody Responses In Humans Infected With Newly Emerging Strains Of West Nile Virus In Europe, Stefan Chabierski, Gustavo R. Makert, Alexandra Kerzhner, Luisa Barzon, Petra Fiebig, Uwe G. Liebert, Anna Papa, Justin M. Richner, Matthias Niedrig, Michael S. Diamond, Giorgio Palu, Sebastian Ulbert
Antibody Responses In Humans Infected With Newly Emerging Strains Of West Nile Virus In Europe, Stefan Chabierski, Gustavo R. Makert, Alexandra Kerzhner, Luisa Barzon, Petra Fiebig, Uwe G. Liebert, Anna Papa, Justin M. Richner, Matthias Niedrig, Michael S. Diamond, Giorgio Palu, Sebastian Ulbert
Open Access Publications
No abstract provided.
Central Nervous System Pathology Progresses Independently Of Kc And Cxcr2 In Globoid-Cell Leukodystrophy, Adarsh S. Reddy, Jigisha R. Patel, Carole Vogler, Robyn S. Klein, Mark S. Sands
Central Nervous System Pathology Progresses Independently Of Kc And Cxcr2 In Globoid-Cell Leukodystrophy, Adarsh S. Reddy, Jigisha R. Patel, Carole Vogler, Robyn S. Klein, Mark S. Sands
Open Access Publications
No abstract provided.