Digital Commons Network^™

Is Phlogenzym Effective In Reducing Moderate To Severe Osteoarthritis Pain In Adults?, Vanessa K. Wood

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not Phlogenzym (or ERC) effective in reducing moderate to severe osteoarthritis pain in adults.

STUDY DESIGN: Review of three randomized controlled trials in the English language from 2001 to 2006.

DATA SOURCES: Two double blind RCTs and one open RCT was found using Cochrane Library EBM Online Database, Ovid Medline, and PubMed Online.

OUTCOMES MEASURED: Each of the three studies measured for pain at rest, pain with motion, and restricted function at baseline assessing efficacy using the Lequesne’s Algofunctional Index, visual analog scales, and …

Does N-Acetylcysteine Supplementation Alleviate Compulsive Behavior In Adults With Impulse Control Disorders?, Tova Diamond

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not “Does N-acetylcysteine supplementation alleviate compulsive behavior in adults with impulse control disorders?”

STUDY DESIGN: Review of three English primary studies published between 2007 and 2009.

DATA SOURCES: One double-blind RCT, one open label trial followed by double-blind RCT, one case study. Studies were found using PubMed, Cochrane Systematic Reviews, OVID and Ebsco databases.

OUTCOMES MEASURED: Primary outcomes measured include severity of trichotillomania symptoms measured by MGHHPS, reduction of pathological gambling symptoms measured by YBOCS-PG, and reduction of compulsive grooming urges measured by patient reports.

RESULTS: In …

Jour 4900/6900: Multimedia Mass Communication (Syllabus), Andrew A. Smith

Journalism and Strategic Media Syllabi Archive

Course Description: Using computers to learn process/software/production design concepts involved in multimedia primarily designed for computer communication; digital editing of still images, off-line video editing, animation and production techniques for assembling all into a single CD or video to convey advertising, public relations, or news editorial concepts.

Jour 4560/6560: Interactive News/Flash (Syllabus), Jin Yang

Journalism and Strategic Media Syllabi Archive

Course Description: Creation and development of interactive news story for web using Flash and its ActionScript; integrating writing, reporting, designing and presenting audio, video, slideshows elements in production of multimedia story.

Jour 4900/6900: Multimedia Mass Communication (Syllabus), Matthew J. Haught

Journalism and Strategic Media Syllabi Archive

Course Description: Using computers to learn process/software/production design concepts involved in multimedia primarily designed for computer communication; digital editing of still images, off-line video editing, animation and production techniques for assembling all into a single CD or video to convey advertising, public relations, or news editorial concepts.

Destroy Or Be Destroyed: Contending With Toxic Social Structures In Naguib Mahfouz’S Midaq Alley, Stephanie Hasenfus

The Oswald Review: An International Journal of Undergraduate Research and Criticism in the Discipline of English

No abstract provided.

No. 19, Fernvale (40wm51), A Late Archaic Occupation Along The South Harpeth River In Williamson County, Tennessee, Aaron Deter-Wolf, Tennessee. Department Of Environment & Conservation.

Archaeology – Research Series

No abstract provided.

Design Of A Running Robot And The Effects Of Foot Placement In The Transverse Plane, Timothy James Sullivan

Open Access Theses

The purpose of this thesis is to make advances in the design of humanoid bipedal running robots. We focus on achieving dynamic running locomotion because it is one metric by which we can measure how far robotic technologies have advanced, in relation to existing benchmarks set by humans and other animals. Designing a running human-inspired robot is challenging because human bodies are exceptionally complex mechanisms to mimic. There are only a few humanoid robots designed specifically for running and the existing robots are either constrained to a plane, do not yet exhibit human-like motion, or are unstable.

One aspect of …

The Impact Of Availability Of Vegetarian Menu Items On Consumers' Behavioral Intention, Mengwei Yue

Open Access Theses

Yue, Mengwei. M.S., Purdue University, December, 2013. The Impact of Availability of Vegetarian Menu Items on Consumers' Behavioral Intention. Major Professor: Douglas C. Nelson.

The purpose of this study is to find out how the availability of vegetarian menu items affects customers' behavioral intention using the theory of planned behavior and the impact vegetarian-friendly menus have on vegetarian as well as non-vegetarian customers when they make their restaurant selections. This paper also discussed the implications for a vegetarian lifestyle on the food service industry and menu development in restaurants. Seven hypotheses related to the relationship among attitudes, subjective norms, perceived …

Best Practices/Teaching Strategies For Teaching Reading In The Primary Grades, Kate Birney

Theses and Dissertations

No abstract provided.

Identifying And Developing Students’ Ability To Reason With Concepts And Representations In Biology, Trevor R. Anderson, Konrad J. Schönborn, Lynn Du Plessis, Abindra S. Gupthar, Tracy L. Hull

PIBERG Publications

External representations (ERs) and their constituent symbolism are of enormous pedagogical value to instructors, especially in the teaching of the submicroscopic world of biology, inherent in disciplines such as biochemistry, immunochemistry, molecular biology and physiology. Whereas symbolic conventions are rigorously applied in physics and chemistry to enhance learning, this is not always true in biology where inappropriate use of symbolic language often leads to confusing ER designs and a range of conceptual, visual, and reasoning difficulties. In this chapter, we present a synthesis of research conducted by our group within these important areas of biology education. We commence by describing …

Cobblestone(S): A Chapbook Companion To Poictesme (2013)

Pwatem (Poictesme), 2006-

Poictesme (pwa-tem) (now Pwatem) is a student-run literary and art journal of Virginia Commonwealth University. Cobblestone(s) is the first ever chapbook companion to Poictesme.

The Global Case Studies Textbook Project: Faculty-Student Research Collaboration In The Business French Classroom, Steven J. Sacco, Dakota E. Senne

Global Business Languages

Despite the need for a new generation of entrepreneurs, higher education continues to train new cadres of employees while neglecting entrepreneurship as a viable career path. In this article, the senior author (a Business French instructor and an entrepreneur) and the junior author (an International Business undergraduate) describe an entrepreneurial class project that culminated in a published book of multimedia Business French (BF) case studies. The Business French class, French 423—divided into five research teams—researched, designed, and created five case studies each in English and French. The cases, published using Articulate Storyline, included a one-page case statement, YouTube videos depicting …

Nicotinic Acetylcholine Receptors Containing Α6 Subunits Contribute To Alcohol Reward-Related Behaviors, Matthew S. Powers, H. J. Broderick, Ryan M. Drenan, Julia Chester

Department of Psychological Sciences Faculty Publications

Evidence is emerging that neuronal nicotinic acetylcholine receptors (nAChRs) in the mesolimbic dopamine (DA) system are involved in mediating the reinforcing effects of alcohol. Midbrain DA neurons express high levels of α6 subunit-containing nAChRs that modulate DA transmission, implicating their involvement in reward-related behaviors. The present study assessed the role of α6-containing nAChRs in modulating alcohol reward using transgenic mice expressing mutant, hypersensitive α6 nAChR subunits (α6L9′S mice). α6L9′S mice and littermate controls were tested in three well-established models of alcohol reward: 24-hr two-bottle choice drinking, drinking in the dark (DID), and conditioned place preference (CPP). Confocal microscopy and patch-clamp …

Modes Of Dislocation: Jewishness And Deafness In Elizabeth Bowen, Maren Linett

Department of English Faculty Publications

Late in her life, Anglo-Irish novelist and short story writer Elizabeth Bowen (1899-1973) wondered why critics did not focus more on place in her writing: “Am I not manifestly a writer for whom places loom large?” (Pictures and Conversations 34). Bowen’s powerful concern with location was animated by the instability of her personal life and the life of her century. She felt dislocated by her father’s mental illness and his voluntary incarceration; by her flight to England with her mother at the age of seven; by their peripatetic life in multiple houses and towns; and most of all, by her …

Developing An Understanding Of Data Management Education: A Report From The Data Information Literacy Project, Jake Carlson, Lisa Johnston, Brian Westra, Mason Nichols

Libraries Faculty and Staff Presentations

This paper describes the initial results from the Data Information Literacy (DIL) project designed to identify the educational needs of graduate students across a variety of science disciplines and respond with effective educational interventions to meet those needs. The DIL project consists of five teams in disparate disciplines from four academic institutions in the United States. The project teams include a data librarian, a subject-specialist librarian, and a faculty member representing a disciplinary group of students. Interviews of the students and faculty members present a detailed snapshot of graduate student needs in data management education. Following our study, educational programs …

Week 03: Exodus 5:1–6:1, Calvin University

Campus Ministries Resources

No abstract provided.

Greenpatch® - Cold Mix Asphalt, Purdue Ect Team

ECT Fact Sheets Archive

GreenPatch® is environmentally friendly cold asphalt that is a direct replacement for traditional cold patch in repairing asphalt pavements. This revolutionary breakthrough in the cold asphalt industry contains no petroleum based softeners such as diesel, toluene, kerosene, and naphthalene found in conventional cold asphalt that pose serious threats to human health and the environment.

The Case For Interposed Abdominal Compression Cpr In Hospital Settings, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Interposed abdominal compression (IAC)-CPR includes all steps of standard external CPR with the addition of manual mid-abdominal compressions in counterpoint to the rhythm of chest compressions. IAC-CPR can increase blood flow during CPR about two fold compared to standard CPR without IAC, as shown by multiple studies in computer and animal models. The technique increases the rate return of spontaneous circulation (ROSC) for in-hospital resuscitations from roughly 25% to 50%. Improved survival to discharge is demonstrated in two in-hospital trials. IAC as an adjunct technique is quickly taught and is less complex than most other basic life support maneuvers. A …

Robust Polyhedral Minkowski Sums With Gpu Implementation, Min-Ho Kyung, Elisha P. Sacks, Victor Milenkovic

Department of Computer Science Technical Reports

No abstract provided.

Usability Evaluation Of A Research Repository And Collaboration Website, Tao Zhang, Deborah J. Maron, Christopher C. Charles

Libraries Faculty and Staff Scholarship and Research

This article reports results from an empirical usability evaluation of Human-Animal Bond Research Initiative Central as part of the effort to develop an open access research repository and collaboration platform for human-animal bond researchers. By repurposing and altering key features of the original HUBzero system, Human-Animal Bond Research Initiative Central hosts previously published materials from related disciplines and an extensive bibliography, in addition to traditional hub materials such as tools and datasets. Seven graduate students in the College of Veterinary Medicine at Purdue University participated in the usability evaluation. Tasks included exploring the system, finding an article in the repository, …

Blindness And Intimacy In Early Twentieth-Century Literature, Maren Linett

Department of English Faculty Publications

This essay traces an association between blindness and intimacy in J.M. Synge’s The Well of the Saints, Florence Barclay’s The Rosary, and D.H. Lawrence’s “The Blind Man,” suggesting that the association participates in an early twentieth-century devaluation of vision and stems from beliefs about knowledge and communication.

Relation Between Corticosterone And Fear-Related Behavior In Mice Selectively Bred For High Or Low Alcohol Preference, Julia Chester, Aaron M. Kirchhoff, Gustavo D. Barrenha

Department of Psychological Sciences Faculty Publications

Blunted cortisol responses to stress or trauma have been linked with genetic (familial) risk for both alcoholism and post-traumatic stress-disorder (PTSD). Mouse lines selectively bred for high (HAP) or low (LAP) alcohol preference may be a relevant model of genetic risk for co-morbid alcoholism and PTSD in humans. HAP mice show greater fear-potentiated startle (FPS), a model used to study PTSD, than LAP mice. The relation between corticosterone (CORT) and FPS behavior was explored in four experiments. Naïve male and female HAP2 and LAP2 mice received fear-conditioning or control treatments and CORT levels were measured before and immediately after fear-conditioning …

Inhibition Of The Host Translation Shutoff Response By Herpes Simplex Virus 1 Triggers Nuclear Envelope-Derived Autophagy, Kerstin Radtke, Luc English, Christiane Rondeau, David Leib

Dartmouth Scholarship

Macroautophagy is a cellular pathway that degrades intracellular pathogens and contributes to antigen presentation. Herpes simplex virus 1 (HSV-1) infection triggers both macroautophagy and an additional form of autophagy that uses the nuclear envelope as a source of membrane. The present study constitutes the first in-depth analysis of nuclear envelope-derived autophagy (NEDA). We established LC3a as a marker that allowed us to distinguish between NEDA and macroautophagy in both immunofluorescence and flow cytometry. NEDA was observed in many different cell types, indicating that it is a general response to HSV-1 infection. This autophagic pathway is known to depend on the …

Modulation Of Renin Secretion By Renal Cortical Interstitial Calcium, Douglas K. Atchison

Wayne State University Dissertations

Renin is secreted from the juxtaglomerular (JG) cells of the afferent arteriole of the kidney, and is the rate-limiting enzyme of the renin-angiotensin system. Renin is quantified in vivo as plasma renin activity (PRA). Acutely elevating plasma calcium decreases PRA, but the mechanisms by which this occurs is unknown. The overall goal of our study was to determine how elevated plasma calcium decreases PRA. The calcium-sensing receptor (CaSR) is a ubiquitously expressed receptor that translates changes in plasma calcium into changes in intracellular signaling. JG cells are basolaterally bordered by the renal cortical interstitium, and parathyroid hormone (PTH) positively regulates …

Cytogenetic Analysis Of Depleted Uranium Exposure And Age-Dependent Susceptibility To Ionizing Radiation, Marina Victoria Bakhmutsky

Wayne State University Dissertations

Chapters 2 and 3:

Depleted Uranium (DU) is a high-density heavy metal that has been used in munitions since the 1991 Gulf War. DU is weakly radioactive and chemically toxic and long term exposure may cause adverse health effects. This study evaluates genotoxic effects of DU exposure in Gulf War I Veterans as a function of uranium (U) body burden by measuring chromosome damage in peripheral blood lymphocytes with the cytokinesis blocked micronucleus assay (CBMN) and fluorescence in situ hybridization (FISH) whole chromosome painting. Study subjects are Gulf War I Veterans exposed to DU during friendly fire incidents in 1991 …

Insight Into Human Brain Evolution Through Phylogenetic Analysis And Comparative Genomics, Amy Marie Boddy

Wayne State University Dissertations

As a species, humans are often considered to be unique among mammals, with respect to their large brain size and enhanced cognitive abilities. Humans are the most encephalized mammals, with a brain that is six times larger than expected relative to body mass. Presumably, it is this high degree of encephalization that underlies our advanced cognitive abilities, including the skills needed for complex language and culture. Understanding how large brains evolved can shed light on what makes the human brain unique and introduce possible mechanism for human specific neurodegenerative diseases. This study takes a both a phenotypic and molecular approach …

Charitable Giving: Motivations, Deterrents & Consequences, Jennifer Lawson

Wayne State University Dissertations

Charitable giving has been suggested to be beneficial to everyone involved in the activity. This study has shown charitable giving can be costly to involved participants. Motives, deterrents and outcomes of charitable giving will be discussed in this paper. Implications for future practice and study will also be discussed.

Investigation Of X Chromosome Recognition: The Role Of Small Rna In Drosophila Dosage Compensation, Debashish Unnikrishnan Menon

Wayne State University Dissertations

In humans and flies, females have two X chromosomes but males have one X chromosome and one Y chromosome. This leads to a fatal imbalance in X-linked gene expression in one sex. In mammals and in the fruit fly Drosophila, modulation of X chromosome expression is critical for survival. This process is termed dosage compensation. Flies increase expression from the male X chromosome two-fold. This is achieved by the Male Specific Lethal (MSL) complex, which consists of two large, non-coding RNA on the X transcripts (roX1 and roX2) and five proteins. The roX RNAs have a critical …

A Qualitative Study: Integrating Art And Science In The Environment, Deborah Naughton Mills

Wayne State University Dissertations

The study was used to develop an understanding of the nature of a creative learning experience that incorporated the foundational elements of Reggio Emilia, place-based education, and experience design. The study took place in an urban high school with eight students in an advanced placement art class. The qualitative research project revolved around the pollinator garden that the science teacher planted in the year prior to the study and the garden that was planted in the spring. Students were asked to create an art project that could withstand the Michigan climate. The science teacher lectured on elements of the pollinator …