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2012

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Mechanism Of Action Of A Novel Antifungal Compound, Amber Ward Jan 2012

Mechanism Of Action Of A Novel Antifungal Compound, Amber Ward

Honors Theses

Opportunistic fungal infections have become problematic in recent years. There has been an emergence of new fungal pathogens, development of antifungal resistance, and increasing prevalence. In addition, toxicity, resistance, and lack of efficacy as a single agent limit the effectiveness of current antifungal drugs. Therefore, new drugs targeting new pathways are greatly needed. An analog derived from the marine natural product phloeodictine, analog PHL5-34A, was identified as having strong in vitro antifungal activity. In this study, its mechanism of action (MOA) was investigated in the model yeast, Saccharomyces cerevisiae. This study made use of a collection of 166 yeast mutants …


Working Towards A Solution To The Obesity Epidemic: A Marketer's Perspective, Elizabeth Ann Clippard Jan 2012

Working Towards A Solution To The Obesity Epidemic: A Marketer's Perspective, Elizabeth Ann Clippard

Honors Theses

The obesity epidemic is a social issue in that critics are quick to blame business and government for failing the consumers. The truth is that all three parties have failed each other by allowing such a cultural change to occur. The issue is similar to the tobacco public health crisis following the spike in lung cancer in the 1950s and 60s. The tobacco companies were blamed entirely for their unhealthy products and the government still spends millions today regulating their products. In order to improve upon this course of action, I believe that a more cooperative solution exists in order …


History, Culture, And Religion In The Development Of Racial Ideology: A Case Study Of The Dutch Reformed Church Of South Africa And The Presbyterian Church Of America, Alexandria Claire Denton Jan 2012

History, Culture, And Religion In The Development Of Racial Ideology: A Case Study Of The Dutch Reformed Church Of South Africa And The Presbyterian Church Of America, Alexandria Claire Denton

Honors Theses

This thesis deals with the Christian religious tradition in relation to the ideology of white supremacy. By contrasting the history and ideologies of the Dutch Reformed Church of South Africa and the Presbyterian Church of America, this thesis will attempt to show that past history and the present culture affect the way religious communities interpret sacred texts. The primary objective of this thesis is to demonstrate the interactive role of history, culture, and religion within religious communities and society in order to breed conscious awareness of how these institutions are mutually effective. Religious adherents are not only products of their …


A Historical Perspective Of Ponzi Schemes, Elizabeth Ann Geny Jan 2012

A Historical Perspective Of Ponzi Schemes, Elizabeth Ann Geny

Honors Theses

In 2008, the largest Ponzi scheme was discovered—Bemie Madoff cheated investors out of over $50 billion. This left the public with many questions regarding Ponzi schemes. This paper reviews the history of Ponzi schemes including what a Ponzi scheme is. It analyzes Ponzi schemes prior to Bernie Madoff, analyzes Madoff s scheme, and analyzes Ponzi schemes discovered after Madoff. This paper also analyzes various Ponzi schemes throughout history and the role the SEC has played in them. It reviews why the SEC missed Madoff and precautions they are taking to never let such a large scale scheme pass them again. …


Uvas Unidas: A Research Study And Campaign Design For Hispanic Millennials, Candace Margaret Rodriguez Jan 2012

Uvas Unidas: A Research Study And Campaign Design For Hispanic Millennials, Candace Margaret Rodriguez

Honors Theses

The Hispanic market is a fast growing demographic that has begun to drastically reshape the population composition of the United States. Many unique and different cultures and identities are represented under the label, “Hispanic." Many companies have started l recognizing the value and importance of the Hispanic demographic. Along with the rising Hispanic population, Millennials are becoming an increasingly significant market. Hispanics have a lower median age, 25.4, than both African Americans and Caucasians in the United States and play a vital role as members of the Millennial generation. Hispanic Millennials are a market segment that is often overlooked. A …


Angiotensin Ii As A Potential Regulator Of Inflammatory Cytokines In Inducing Hypertension In Systemic Lupus Erythematosus, Khush Singh Aujla Jan 2012

Angiotensin Ii As A Potential Regulator Of Inflammatory Cytokines In Inducing Hypertension In Systemic Lupus Erythematosus, Khush Singh Aujla

Honors Theses

The disease Systemic Lupus Erythematosus is a chronic inflammatory, autoimmune disorder that primarily affects women during their reproductive years. Women with SLE are at a greater risk of developing hypertension, which increases their risk of mortality from a cardiac related event. A proposed mechanism for SLE hypertension suggests that inflammation in the kidneys causes renal dysfunction, presumably resulting in less water excretion, increased plasma volume, and thus high blood pressure. This experiment tests the hypothesis that the T-cells from a mouse model of SLE hyper secrete the inflammatory cytokines IL-17, IL-10, and DFN- y, and are more sensitive to the …


The Influence Of Johann Wolfgang Von Goethe On The Legacy Of The Bauhaus, Zachary Whiteaker Branson Jan 2012

The Influence Of Johann Wolfgang Von Goethe On The Legacy Of The Bauhaus, Zachary Whiteaker Branson

Honors Theses

This paper addresses three color theorists of the Bauhaus and their connection to a single historical source, Johann Wolfgang von Goethe. It begins with an overview of the Bauhaus and a brief chronology of the school, and then moves into a description of Goethe’s work, primarily Theory of Color. I then discuss Wassily Kandinsky, his writings in Concerning the Spiritual in Art and From Point and Line to Plane, and his impact on the other teachers of the Bauhaus. The third chapter addresses Johannes Itten’s book. The Art of Color, and his influence on the Bauhaus and its students through …


Investigations Of Physiological Changes In Gulf Of Mexico Sharks During Acute Stress Events With Emphasis On The Atlantic Sharp Nose Shark, Wood Whittington Dale Jan 2012

Investigations Of Physiological Changes In Gulf Of Mexico Sharks During Acute Stress Events With Emphasis On The Atlantic Sharp Nose Shark, Wood Whittington Dale

Honors Theses

Blood samples were taken from seven species of shark found in the Gulf of Mexico. The species examined were Atlantic sharpnose (Rhizoprionodon terraenovae), blacknose (Carcharhinus acronotus), blacktip [Carcharhinus limbatus), bull {Carcharhinus leucas), finetooth {Carcharhinus isodon), spinner (Carcharhinus brevipinna), and tiger (Galeocerdo cuvier). The blood of 63 sharks was collected and analyzed for hematocrit, leukocrit, and plasma percent volume. Plasma osmolality values were also analyzed. Sharks were captured using hook and line (n=24) and longline (n=39). Hook and line captured sharks were submitted to a stress protocol described by Hoffmayer and Parsons (2001) and longline captured sharks were submitted to a …


An Investigation Of Host Variation In The Host-Parasite Interaction Of Sciurus Carolinensis And Cuterebra Emasculator, Miles Moore Debardeleben Jan 2012

An Investigation Of Host Variation In The Host-Parasite Interaction Of Sciurus Carolinensis And Cuterebra Emasculator, Miles Moore Debardeleben

Honors Theses

Within a population, susceptibility to parasitism may vary. Individuals possessing certain intrinsic or extrinsic traits are often more likely to be parasitized than individuals within that population that do not possess those certain traits. As a result, parasites can have profound effects of the population dynamics of theirs hosts. Much research has been done on the host-parasite interaction of the eastern grey squirrel {Sciurus caroUnensis) and the tree squirrel hot fly {Cuterebra emasculator). However, relatively little research has been done on host susceptibility to this parasite. Knowing that bot flies can lower reproductive success, reduce fitness, and cause death of …


The Effect Of Temperature And Turbidity On The Swimming Performance Of Golden Shiner (Notemigonus Crysoleucas)., Emily Katherine Hildebrandt Jan 2012

The Effect Of Temperature And Turbidity On The Swimming Performance Of Golden Shiner (Notemigonus Crysoleucas)., Emily Katherine Hildebrandt

Honors Theses

The purpose of this study was to examine the effects of turbidity and temperature on golden shiner critical swimming speed, and tail beat frequency, and how these relationships might be altered when fish are in a group. It was found that both temperature and turbidity positively affected critical swimming speeds; critical swimming speeds increased significantly with rising temperature and turbidity values. Tail beat frequencies increased with increasing temperature and turbidity, echoing the rise in critical swimming speed. A group effect was only evident at the lowest temperature for the highest turbidity, but tail beat frequencies indicate greater stress when alone …


Investigation Of Brown Recluse (Loxosceles Reclusa) And Black Widow (Latrodectus Mactans) Spider-Bite Diagnoses By Medical Professionals Across Three Regions Of Mississippi, Hillary Michelle Howell Jan 2012

Investigation Of Brown Recluse (Loxosceles Reclusa) And Black Widow (Latrodectus Mactans) Spider-Bite Diagnoses By Medical Professionals Across Three Regions Of Mississippi, Hillary Michelle Howell

Honors Theses

During 4 weeks of the spring of 2011 and 5 weeks of the fall of 2011, interviews were conducted with medical professionals practicing in Mississippi regarding the diagnosis of brown recluse {Loxosceles reclusa) and black widow {Latrodectus mactans) spider bites. During the spring, a total of 19 interviews were held with emergency room physicians and dermatologists practicing in urban and rural, non-medically underserved areas of Mississippi. The participants varied in their location of practice across the 3 regions of Mississippi. During the fall, a total of 5 interviews were conducted with nurse practitioners and one pediatrician practicing in rural, medically …


Table Of Contents , Depaul College Of Law Jan 2012

Table Of Contents , Depaul College Of Law

DePaul Law Review

No abstract provided.


Introduction: Festschrift For Robert Rabin: Seventeenth Annual Clifford Symposium On Tort Law And Social Policy, Stephan Landsman Jan 2012

Introduction: Festschrift For Robert Rabin: Seventeenth Annual Clifford Symposium On Tort Law And Social Policy, Stephan Landsman

DePaul Law Review

No abstract provided.


Strict Liability In Negligence, Kenneth S. Abraham Jan 2012

Strict Liability In Negligence, Kenneth S. Abraham

DePaul Law Review

No abstract provided.


Reflections On Tort And The Administrative State, Robert L. Rabin Jan 2012

Reflections On Tort And The Administrative State, Robert L. Rabin

DePaul Law Review

No abstract provided.


An Alternative Explanation For No-Fault's Demise, Nora Freeman Engstrom Jan 2012

An Alternative Explanation For No-Fault's Demise, Nora Freeman Engstrom

DePaul Law Review

No abstract provided.


Public-Private Approaches To Mass Tort Victim Compensation: Some Thoughts On The Gulf Coast Claims Facility, Myriam Gilles Jan 2012

Public-Private Approaches To Mass Tort Victim Compensation: Some Thoughts On The Gulf Coast Claims Facility, Myriam Gilles

DePaul Law Review

No abstract provided.


The Coherence Of Compensation-Deterrence Theory In Tort Law, Mark A. Geistfeld Jan 2012

The Coherence Of Compensation-Deterrence Theory In Tort Law, Mark A. Geistfeld

DePaul Law Review

No abstract provided.


Recovering Rylands: An Essay For Robert Rabin, Gregory C. Keating Jan 2012

Recovering Rylands: An Essay For Robert Rabin, Gregory C. Keating

DePaul Law Review

No abstract provided.


Convergence And Contrast In Tort Scholarship: An Essay In Honor Of Robert Rabin, John C.P. Goldberg, Benjamin C. Zipursky Jan 2012

Convergence And Contrast In Tort Scholarship: An Essay In Honor Of Robert Rabin, John C.P. Goldberg, Benjamin C. Zipursky

DePaul Law Review

No abstract provided.


Professor Rabin And The Administrative State , Peter H. Schuck Jan 2012

Professor Rabin And The Administrative State , Peter H. Schuck

DePaul Law Review

No abstract provided.


Pure Confusion: Should Pure Licensors Share The Products Liability Of Manufacturers And Sellers Of Dangerously Defective Products?, Stephen C. Jarvis Jan 2012

Pure Confusion: Should Pure Licensors Share The Products Liability Of Manufacturers And Sellers Of Dangerously Defective Products?, Stephen C. Jarvis

DePaul Law Review

No abstract provided.


The Federal Employers' Liability Act: Sense And Nonsense About Causation, Michael D. Green Jan 2012

The Federal Employers' Liability Act: Sense And Nonsense About Causation, Michael D. Green

DePaul Law Review

No abstract provided.


Against Categorical Preemption: Vaccines And The Compensation Piece Of The Preemption Puzzle, Catherine M. Sharkey Jan 2012

Against Categorical Preemption: Vaccines And The Compensation Piece Of The Preemption Puzzle, Catherine M. Sharkey

DePaul Law Review

No abstract provided.


Why No Duty?, Stephen D. Sugarman Jan 2012

Why No Duty?, Stephen D. Sugarman

DePaul Law Review

No abstract provided.


The Innovative Design Protection And Piracy Prevention Act: Re-Fashioning U.S. Intellectual Property Law, Katherine M. Olson Jan 2012

The Innovative Design Protection And Piracy Prevention Act: Re-Fashioning U.S. Intellectual Property Law, Katherine M. Olson

DePaul Law Review

No abstract provided.


Whom Must The Clergy Protect: The Interests Of At-Risk Children In Conflict With Clergy-Penitent Privilege, Paul Winters Jan 2012

Whom Must The Clergy Protect: The Interests Of At-Risk Children In Conflict With Clergy-Penitent Privilege, Paul Winters

DePaul Law Review

No abstract provided.


The Effects Of The Histidine-Alanine-Valine Peptide On The Dimerization Of Neural Cadherin, Ariel Rogers Jan 2012

The Effects Of The Histidine-Alanine-Valine Peptide On The Dimerization Of Neural Cadherin, Ariel Rogers

Honors Theses

Cadherins are calcium-dependent cell adhesion molecules whose general structure is characterized by three regions: a conserved carboxy-terminal cytoplasmic region, a transmembrane segment and an extracellular region that binds calcium. Cadherins mediate cell to cell adhesion by the formation of homophilic dimers between these extracellular regions, during which one cadherin molecule interacts with another cadherin molecule of the same type. The adhesive interface is a strand-crossover structure between two protomers from adjacent cells. The PA-strand detaches from its own protomer and crosses over to dock a critical tryptophan residue in a hydrophobic partner protomer. Disruption of the formation of the adhesive …


Uneven-Ing, Samantha Taylor Ivy Jan 2012

Uneven-Ing, Samantha Taylor Ivy

Honors Theses

No abstract provided.


“High School For Scandal: A Modern Screenplay Adaptation Of Richard Brinsley Sheridan’S The School For Scandal”, Bryant Alexander Salmon Jan 2012

“High School For Scandal: A Modern Screenplay Adaptation Of Richard Brinsley Sheridan’S The School For Scandal”, Bryant Alexander Salmon

Honors Theses

For my thesis, I adapted Richard Brinsley Sheridan’s IS**’ century play. The School for Scandal, into a modern-day screenplay with an American high school setting. I not only modified the characters and setting of Sheridan's play, but also changed the format from that of a play, meant for the stage, into an on-screen, feature-length film. Through extensive research on the art of screenwriting, adaptation, and film editing, I created a modem script that shares similar themes, attitudes, and messages with Sheridan’s original play. The works together show parallels and similarities between the British aristocracy of Sheridan’s time and the social …