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Articles 32011 - 32040 of 33109
Full-Text Articles in Entire DC Network
An Analysis Of The Transcriptome Of Teladorsagia Circumcincta: Its Biological And Biotechnological Implications, Ranjeeta Menon, Robin B. Gasser, Makedonka Mitreva, Shoba Ranganathan
An Analysis Of The Transcriptome Of Teladorsagia Circumcincta: Its Biological And Biotechnological Implications, Ranjeeta Menon, Robin B. Gasser, Makedonka Mitreva, Shoba Ranganathan
Open Access Publications
No abstract provided.
Hypergrowth Mtorc1 Signals Translationally Activate The Arf Tumor Suppressor Checkpoint, Alexander P. Miceli, Anthony J. Saporita, Jason D. Weber
Hypergrowth Mtorc1 Signals Translationally Activate The Arf Tumor Suppressor Checkpoint, Alexander P. Miceli, Anthony J. Saporita, Jason D. Weber
Open Access Publications
No abstract provided.
Mhc Class I Cross-Presentation By Dendritic Cells Counteracts Viral Immune Evasion, Katrin Nopora, Caroline A. Bernhard, Christine Ried, Alejandro A. Castello, Kenneth M. Murphy, Peggy Marconi, Ulrich Koszinowski, Thomas Brocker
Mhc Class I Cross-Presentation By Dendritic Cells Counteracts Viral Immune Evasion, Katrin Nopora, Caroline A. Bernhard, Christine Ried, Alejandro A. Castello, Kenneth M. Murphy, Peggy Marconi, Ulrich Koszinowski, Thomas Brocker
Open Access Publications
No abstract provided.
Ahr And The Transcriptional Regulation Of Type-17/22 Ilc, Jacob S. Lee, Marina Cella, Marco Colonna
Ahr And The Transcriptional Regulation Of Type-17/22 Ilc, Jacob S. Lee, Marina Cella, Marco Colonna
Open Access Publications
No abstract provided.
Transposon Mutagenesis Identifies Uropathogenic Escherichia Coli Biofilm Factors, Maria Hadjifrangiskou, Alice P. Gu, Jerome S. Pinkner, Maria Kostakioti, Ellisa W. Zhang, Sarah E. Greene, Scott J. Hultgren
Transposon Mutagenesis Identifies Uropathogenic Escherichia Coli Biofilm Factors, Maria Hadjifrangiskou, Alice P. Gu, Jerome S. Pinkner, Maria Kostakioti, Ellisa W. Zhang, Sarah E. Greene, Scott J. Hultgren
Open Access Publications
No abstract provided.
Social Cognition In Williams Syndrome: Relations Between Performance On The Social Attribution Task And Cognitive And Behavioral Characteristics, Faye Van Der Fluit, Michael S. Gaffrey, Bonita P. Klein-Tasman
Social Cognition In Williams Syndrome: Relations Between Performance On The Social Attribution Task And Cognitive And Behavioral Characteristics, Faye Van Der Fluit, Michael S. Gaffrey, Bonita P. Klein-Tasman
Open Access Publications
No abstract provided.
When Planning Results In Loss Of Control: Intention-Based Reflexivity And Working-Memory, Nachshon Meiran, Michael W. Cole, Todd S. Braver
When Planning Results In Loss Of Control: Intention-Based Reflexivity And Working-Memory, Nachshon Meiran, Michael W. Cole, Todd S. Braver
Open Access Publications
No abstract provided.
Combinatorial Small-Molecule Therapy Prevents Uropathogenic Escherichia Coli Catheter-Associated Urinary Tract Infections In Mice, Pascale S. Guiton, Corinne K. Cusumano, Kimberly A. Kline, Karen W. Dodson, Zhenfu Han, James W. Janetka, Jeffrey P. Henderson, Michael G. Caparon, Scott J. Hultgren
Combinatorial Small-Molecule Therapy Prevents Uropathogenic Escherichia Coli Catheter-Associated Urinary Tract Infections In Mice, Pascale S. Guiton, Corinne K. Cusumano, Kimberly A. Kline, Karen W. Dodson, Zhenfu Han, James W. Janetka, Jeffrey P. Henderson, Michael G. Caparon, Scott J. Hultgren
Open Access Publications
No abstract provided.
Interaction Of Card With Rna Polymerase Mediates Mycobacterium Tuberculosis Viability, Rifampin Resistance, And Pathogenesis, Leslie A. Weiss, Phillip G. Harrison, Bryce E. Nickels, Michael S. Glickman, Elizabeth A. Campbell, Seth A. Darst, Christina L. Stallings
Interaction Of Card With Rna Polymerase Mediates Mycobacterium Tuberculosis Viability, Rifampin Resistance, And Pathogenesis, Leslie A. Weiss, Phillip G. Harrison, Bryce E. Nickels, Michael S. Glickman, Elizabeth A. Campbell, Seth A. Darst, Christina L. Stallings
Open Access Publications
No abstract provided.
The L.E.A.D. Framework: Using Tools From Evidence-Based Public Health To Address Evidence Needs For Obesity Prevention, Shiriki Kumanyika, Ross C. Brownson, Allen Cheadle
The L.E.A.D. Framework: Using Tools From Evidence-Based Public Health To Address Evidence Needs For Obesity Prevention, Shiriki Kumanyika, Ross C. Brownson, Allen Cheadle
Open Access Publications
No abstract provided.
State Legislation Savvy: A Primer And Tools For Online Legislative Research In The United States, Leah M. Nguyen, Amy A. Eyler, Jooyoung Kong, Ross C. Brownson
State Legislation Savvy: A Primer And Tools For Online Legislative Research In The United States, Leah M. Nguyen, Amy A. Eyler, Jooyoung Kong, Ross C. Brownson
Open Access Publications
No abstract provided.
Differential Replication Of Pathogenic And Nonpathogenic Strains Of West Nile Virus Within Astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, Brenda L. Fredericksen
Differential Replication Of Pathogenic And Nonpathogenic Strains Of West Nile Virus Within Astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, Brenda L. Fredericksen
Open Access Publications
No abstract provided.
The Evolution Of African Great Ape Subtelomeric Heterochromatin And The Fusion Of Human Chromosome 2, Mario Ventura, Claudia R. Catacchio, Saba Sajjadian, Laura Vives, Peter H. Sudmant, Tomas Marques-Bonet, Tina A. Graves, Richard K. Wilson, Evan E. Eichler
The Evolution Of African Great Ape Subtelomeric Heterochromatin And The Fusion Of Human Chromosome 2, Mario Ventura, Claudia R. Catacchio, Saba Sajjadian, Laura Vives, Peter H. Sudmant, Tomas Marques-Bonet, Tina A. Graves, Richard K. Wilson, Evan E. Eichler
Open Access Publications
No abstract provided.
Five-Year Update On The Mouse Model Of Orthotopic Lung Transplantation: Scientific Uses, Tricks Of The Trade, And Tips For Success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander S. Krupnick
Five-Year Update On The Mouse Model Of Orthotopic Lung Transplantation: Scientific Uses, Tricks Of The Trade, And Tips For Success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander S. Krupnick
Open Access Publications
No abstract provided.
Hedgehog-Targeted Therapeutics Uncouple The Vicious Cycle Of Bone Metastasis, Michelle A. Hurchla, Katherine N. Weilbaecher
Hedgehog-Targeted Therapeutics Uncouple The Vicious Cycle Of Bone Metastasis, Michelle A. Hurchla, Katherine N. Weilbaecher
Open Access Publications
No abstract provided.
Zbtb46 Expression Distinguishes Classical Dendritic Cells And Their Committed Progenitors From Other Immune Lineages, Ansuman T. Satpathy, Wumesh Kc, Jörn C. Albring, Brian T. Edelson, Nicole M. Kretzer, Deepta Bhattacharya, Theresa L. Murphy, Kenneth M. Murphy
Zbtb46 Expression Distinguishes Classical Dendritic Cells And Their Committed Progenitors From Other Immune Lineages, Ansuman T. Satpathy, Wumesh Kc, Jörn C. Albring, Brian T. Edelson, Nicole M. Kretzer, Deepta Bhattacharya, Theresa L. Murphy, Kenneth M. Murphy
Open Access Publications
Distinguishing dendritic cells (DCs) from other cells of the mononuclear phagocyte system is complicated by the shared expression of cell surface markers such as CD11c. In this study, we identified Zbtb46 (BTBD4) as a transcription factor selectively expressed by classical DCs (cDCs) and their committed progenitors but not by plasmacytoid DCs (pDCs), monocytes, macrophages, or other lymphoid or myeloid lineages. Using homologous recombination, we replaced the first coding exon of Zbtb46 with GFP to inactivate the locus while allowing detection of Zbtb46 expression. GFP expression in Zbtb46(gfp/+) mice recapitulated the cDC-specific expression of the native locus, being restricted to cDC …
Dna2 And Exo1 In Replication-Coupled, Homology-Directed Repair And In The Interplay Between Hdr And The Fa/Brca Network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, Judith L. Campbell
Dna2 And Exo1 In Replication-Coupled, Homology-Directed Repair And In The Interplay Between Hdr And The Fa/Brca Network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, Judith L. Campbell
Open Access Publications
No abstract provided.
Evaluating The Impact Of Electronic Health Records On Clinical Reasoning Performance, Matthew J. Wills, Omar F. El-Gayar, Amit Deokar
Evaluating The Impact Of Electronic Health Records On Clinical Reasoning Performance, Matthew J. Wills, Omar F. El-Gayar, Amit Deokar
Research & Publications
This paper adapts and extends the task-technology fit model of performance to the health care domain and the clinical reasoning task. Central to this effort was careful adaptation of the task and technology characteristics constructs to the clinical reasoning task and electronic health record technology. Overall the results indicate a good fit between model and data. The contributions of this study include successful adaptation of a corner-stone information systems theory to a new domain and technology, a validated user evaluation instrument able to assess the impact of EHR use on clinical reasoning performance, and new insight on the factors that …
Security Policy Compliance: User Acceptance Perspective, Ahmad Al-Omari, Omar F. El-Gayar, Amit Deokar
Security Policy Compliance: User Acceptance Perspective, Ahmad Al-Omari, Omar F. El-Gayar, Amit Deokar
Research & Publications
Information security policy compliance is one of the key concerns that face organizations today. Although, technical and procedural security measures help improve information security, there is an increased need to accommodate human, social and organizational factors. While employees are considered the weakest link in information security domain, they also are assets that organizations need to leverage effectively. Employees’ compliance with Information Security Policies (ISPs) is critical to the success of an information security program. The purpose of this research is to develop a measurement tool that provides better measures for predicting and explaining employees’ compliance with ISPs by examining the …
Underwater Object Detection And Identification Using Distributed Pressure Sensors, Audrey Maertens
Underwater Object Detection And Identification Using Distributed Pressure Sensors, Audrey Maertens
Link Foundation Ocean Engineering and Instrumentation Fellowship Reports
Underwater vision is usually limited. Object detection and identification is therefore one of the main challenges of underwater navigation. A new sensing modality, specifically developed for underwater environments, would greatly increase the scope of underwater missions. Taking inspiration from the lateral line of fish, I believe that pressure sensing can be a viable alternative to vision in order to detect and identify obstacles. Recent advances in the area of micro-engineering will soon enable to build sensors that match the size and mimic the functions and organization of the lateral line. However, little is known about how the pressure distribution along …
Sexual Harassment 2.0, Mary Anne Franks
Sexual Harassment 2.0, Mary Anne Franks
Articles
Sexual harassment is a complex and evolving practice. The rise of sexual discrimination in cyberspace is only one of the most recent and most striking examples of the phenomenon's increasing complexity. Sexual harassment law, however, has not kept pace with this evolution. Discrimination law has not been adequately "updated" to address new and amplified practices of sex discrimination. Its two principal limitations are (1) it treats only sexual harassment that occurs in certain protected settings (e.g. the workplace or school) as actionable and (2) it assumes that both the activity and the resulting harm of sexual harassment occur in the …
In Memoriam David J. Bederman (1961-2011), Bernard H. Oxman
In Memoriam David J. Bederman (1961-2011), Bernard H. Oxman
Articles
No abstract provided.
Introduction: Jessica Lenahan (Gonzales) V. United States: Implementation, Litigation, And Mobilization Strategies, Caroline Bettinger-López
Introduction: Jessica Lenahan (Gonzales) V. United States: Implementation, Litigation, And Mobilization Strategies, Caroline Bettinger-López
Articles
No abstract provided.
The Mindful Law School: An Integrative Approach To Transforming Legal Education, Scott L. Rogers
The Mindful Law School: An Integrative Approach To Transforming Legal Education, Scott L. Rogers
Articles
No abstract provided.
Cardiac Pi3kα Signaling And K+ Channel Regulation In Cardiac Hypertrophy And Heart Failure, Kai-Chien Yang
Cardiac Pi3kα Signaling And K+ Channel Regulation In Cardiac Hypertrophy And Heart Failure, Kai-Chien Yang
All Theses and Dissertations (ETDs)
Pathologic biomechanical stresses cause cardiac hypertrophy, which is associated with QT prolongation and increased risk of life-threatening ventricular arrhythmias. Previous studies demonstrated that repolarizing K+ current densities are decreased in pressure overload-induced left ventricular hypertrophy, resulting in action potential and QT prolongation. Cardiac hypertrophy also occurs with exercise training, but this "physiological hypertrophy" is not associated with electrical abnormalities or increased arrhythmia risk, suggesting that repolarizing K+ currents are upregulated, in parallel with the increase in myocyte size, to maintain normal cardiac function. To explore this hypothesis directly, two mouse models of physiological hypertrophy, one produced by chronic exercise: swim-) …
Joint Functions Of Mett-10 And Dynein In The Caenorhabditis Elegans Germ Line, Maia Dorsett
Joint Functions Of Mett-10 And Dynein In The Caenorhabditis Elegans Germ Line, Maia Dorsett
All Theses and Dissertations (ETDs)
During normal development as well as in diseased states such as cancer, extracellular "niches" often provide cues to proximal cells and activate intracellular pathways. Activation of such signaling pathways in turn instructs cellular proliferation and differentiation. In the C.elegans gonad, GLP-1/Notch signaling instructs germ line stem cells to self renew through mitotic cell division. As germ cells progressively move out of the niche, they differentiate by entering meiosis and eventually form gametes. Using this model system, I uncovered a cooperative role for the METT-10 putative methyltransferase and the dynein motor complex in regulating the balance between germ cell proliferation and …
Taspase1 Is A Non-Oncogene Mediator Of Tumorigenesis And Maintenance, David Chen
Taspase1 Is A Non-Oncogene Mediator Of Tumorigenesis And Maintenance, David Chen
All Theses and Dissertations (ETDs)
The clinical success of oncogene-targeted therapies substantiates the continued reliance of certain cancers upon the continued function of apical oncogenes involved in its genesis--a phenomenon known as "oncogene addiction." Though this shift from non-targeted, cytotoxic therapies offers new hope to patients, resistance to oncogene inactivation often remains an eventuality, and it is clear that further investigation is required to more effectively battle cancer using alternative therapeutic targets. Our studies on Taspase1: threonine aspartase 1) reveal its role in coordinating cellular proliferation and apoptosis in cancer. Loss of Taspase1 by shRNA-mediated knockdown decreased cellular proliferation in a diverse set of cancer …
The Influence Of Rudolf Von Jhering On Karl Llewellyn, Julie E. Grise, Martin Gelter, Robert Whitman
The Influence Of Rudolf Von Jhering On Karl Llewellyn, Julie E. Grise, Martin Gelter, Robert Whitman
Faculty Scholarship
No abstract provided.
Functional Analysis Of Conserved Motifs In The Mechanosensitive Channel Homolog Mscs-Like2 From Arabidopsis Thaliana, Gregory S. Jensen, Elizabeth S. Haswell
Functional Analysis Of Conserved Motifs In The Mechanosensitive Channel Homolog Mscs-Like2 From Arabidopsis Thaliana, Gregory S. Jensen, Elizabeth S. Haswell
Biology Faculty Research
The Mechanosensitive channel of Small conductance (MscS) of Escherichia coli has become an excellent model system for the structural, biophysical, and functional study of mechanosensitive ion channels. MscS, a complex channel with multiple states, contributes to protection against lysis upon osmotic downshock. MscS homologs are widely and abundantly dispersed among the bacterial and plant lineages, but are not found in animals. Investigation into the eukaryotic branch of the MscS family is in the beginning stages, and it remains unclear how much MscS homologs from eukaryotes resemble E. coli MscS with respect to structure, function, and regulation. Here we test the …
Between Semiotic Democracy And Disobedience: Two Views Of Branding, Culture And Intellectualproperty, Sonia K. Katyal
Between Semiotic Democracy And Disobedience: Two Views Of Branding, Culture And Intellectualproperty, Sonia K. Katyal
Faculty Scholarship
Even though most scholars and judges treat intellectual property law as a predominantly content-neutral phenomenon, trademark law contains a statutory provision, section 2(a), that provides for the cancellation of marks that are “disparaging,” “immoral,” or “scandalous.” This provision has raised intrinsically powerful constitutional concerns, which invariably affect two central metaphors that are at war within trademark law: the marketplace of goods, which premises itself on the fixedness of intellectual properties, and the marketplace of ideas, which is premised on the very fluidity of language itself. Since the architecture of trademark law focuses only on how marks communicate information about a …