Digital Commons Network^™

Remote Sensing Evaluation Of Clm4 Gpp For The Period 2000-2009*, Jiafu Mao, Peter Edmond Thornton, Xiaoying Shi

Numerical Terradynamic Simulation Group Publications

Remote sensing can provide long-term and large-scale products helpful for ecosystem model evaluation. The authors compare monthly gross primary production (GPP) simulated by the Community Land Model, version 4 (CLM4) at a half-degree resolution with satellite estimates of GPP from the Moderate Resolution Imaging Spectroradiometer (MODIS) GPP product (MOD17) for the 10-yr period January 2000–December 2009. The assessment is presented in terms of long-term mean carbon assimilation, seasonal mean distributions, amplitude and phase of the annual cycle, and intraannual and interannual GPP variability and their responses to climate variables. For the long-term annual and seasonal means, major GPP patterns are …

Nature's Perfect Food, Geoffrey D. Reynolds

Faculty Publications

Nature's Perfect Food is an article that describes the history of local beekeeper Jack Hartman and the benefit of local honey bees to agriculture and honey consumers.

Algorithms For Optimizing Cross-Overs In Dna Shuffling, Lu He, Alan M. Friedman, Chris Bailey-Kellogg

Dartmouth Scholarship

DNA shuffling generates combinatorial libraries of chimeric genes by stochastically recombining parent genes. The resulting libraries are subjected to large-scale genetic selection or screening to identify those chimeras with favorable properties (e.g., enhanced stability or enzymatic activity). While DNA shuffling has been applied quite successfully, it is limited by its homology-dependent, stochastic nature. Consequently, it is used only with parents of sufficient overall sequence identity, and provides no control over the resulting chimeric library.

Results: This paper presents efficient methods to extend the scope of DNA shuffling to handle significantly more diverse parents and to generate more predictable, optimized libraries. …

Factors Affecting The Distribution And Survival Of Endangered American Burying Beetles, Nicrophorus Americanus Olivier, Jessica Jurzenski

Department of Entomology: Dissertations, Theses, and Student Research

The disappearance of the federally endangered American burying beetle (Nicrophorus americanus Olivier) over most of its range is poorly understood, which is why the identification and evaluation of conservation measures is important. The presence and distribution of all carrion beetles in Nebraska was first reported to help understand where American burying beetles (ABBs) occur to aid in creating a habitat suitability model for the Sandhills ecoregion and to locate suitable experiment areas. There are 18 Nebraska counties with records of ABB presence in the last 15 years. The final habitat suitability model performed well with an AUC value above …

Host-Microbe-Diet Interplay: Dietary Modulation Of The Gut Microbiota In Relation To Health, Inés Martínez

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Vertebrates are associated with trillions of bacteria, with the densest populations residing in the large intestine. The symbiosis between vertebrates and their gut microbiota has resulted in important implications of the gut microbiome on host health. Diet is an important factor that shapes gut microbiota composition, and because of the interplay between host-microbiome-diet, dietary strategies that modulate gut microbiome structure are deemed a relevant tool to improve host health. However, gaps in knowledge exist with respect to these interactions, and it is essential to obtain a mechanistic understanding of how these relations take place to develop successful therapeutic strategies that …

River Otter (Lontra Canadensis) Home Range, Habitat Use, Overnight Movement, And Survival In The Platte River Of Nebraska, Samuel P. Wilson

School of Natural Resources: Dissertations, Theses, and Student Research

River otters (Lontra canadensis) are native to Nebraska but were extirpated by the early 1900s. The Nebraska Game and Parks Commission (NGPC) reintroduced river otters during 1986­–1991 to restore the species in the state but little is known regarding the habitat needs and status of this high profile threatened species. To provide information for management I conducted research to determine home range, habitat use, overnight movement distance, and annual survival of river otters in the central Platte River of Nebraska.

I trapped, implanted telemetry transmitters, and tracked 18 river otters during 2006–2009. I obtained 996 locations and constructed …

Experimental And Theoretical Studies In Nuclear Magnetic Resonance, John D. Persons

Department of Chemistry: Dissertations, Theses, and Student Research

Nuclear Magnetic Resonance (NMR) has proven to be an excellent tool to probe the structure of molecules by gaining insight into nuclear interactions. Used in conjunction with theoretical calculations, NMR has the potential to elucidate these nuclear interactions and how they affect structure, bonding and dynamics on a molecular scale. The first two projects presented herein study the peroxide explosive hexamethylene triperoxide diamine (HMTD). In the first project, we use the characteristics of the solid-state NMR lineshape to determine the ¹⁴N quadrupole coupling constant (C_Q). The second project uses multi-dimensional solution-state NMR and chiral shift reagents …

Spiritual Care Interventions To Improve The Quality Of Life In Patients With Advanced Cancer Receiving Palliative Care, Maria Ballen-Sanchez

HIM 1990-2015

Title: Spiritual Care Interventions and Quality of Life in Cancer Patients Receiving Palliative Care Background: Despite the evidence supporting spiritual care in nursing and an increased quality of life among patients, patients feel that their spiritual needs are not being supported by medical professionals. Nurses agree that the role they play is significant in addressing the needs of cancer patients; however, they feel that they lack the knowledge for addressing spirituality concerns at the end of life. The purpose of this study is to identify spiritual care interventions that nurses can implement to improve quality of life (QOL) in patients …

Amyloid-Beta42 Toxicity Reduction In Human Neuroblastoma Cells Using Cholera Toxin B Subunit-Myelin Basic Protein Expressed In Chloroplasts, Alexandra Ayache

HIM 1990-2015

Alzheimer's disease (AD) is an age progressive neurodegenerative brain disorder, affecting 37 million people worldwide. Cleavage of amyloid precursor protein by ?- and ?-secretase produces the amyloid-beta (A?) protein, which significantly contributes to AD pathogenesis. The A? aggregates, formed at the surface of neurons and intracellularly, cause neurotoxicity and decrease synaptic function. Inhibiting or degrading A? accumulation is a key goal for development of new AD treatments. Evidence shows that human Myelin Basic Protein (MBP) binds to and degrades A? thereby, preventing cytotoxicity. A potential method for oral drug delivery that will allow plant-derived bioencapsulated MBP to pass through intestinal …

Multiple Aspects Of Natural Killer Cell Expansion In Relevance To Immunotherapy For Hematologic Malignancies, Dominic Colosimo

HIM 1990-2015

Natural Killer (NK) cells are a subset of lymphocytes that regulate adaptive immune responses and utilize "missing self" recognition to activate anti-tumor and anti-viral cytotoxicity. Clinical research, as well as murine and ex vivo models, have shown that a variety of NK cell applications have proven useful as immunotherapeutic treatments for patients with hematologic malignancies. However, the selective expansion of NK cells to yield relevant amounts of these lymphocytes has been a major hurdle in the development of methods for clinical therapeutic use. Here, we demonstrate a novel ex vivo expansion method utilizing k562 leukemic cell lines and soluble cytokines …

Has The Pendulum Swung Too Far? A Legal Evaluation Of Florida's Child Abuse And Neglect Registry, Julianna Debler

HIM 1990-2015

Over the past several years, increasing public emphasis on preventing child maltreatment has resulted in substantial changes to Florida's child abuse and neglect central registry. Many of these recent changes, aimed at preventing child maltreatment, have resulted in over one million false, unsubstantiated, and inconclusive reports of child abuse and neglect within the last decade. While the information held in reports may be useful for identifying and preventing potential child abuse or neglect, due process concerns have been raised with regards to the process of placing a person's name in a report without providing a hearing for challenging or removing …

Signals The Interplay Between Literacy, Gender, And Semiotics, Patricia Parker

HIM 1990-2015

The purpose of this study is to examine adult literacy beyond its constraints as a social problem and instead consider the implications of illiteracy as a particular form of lived experience, analogous to women's oppression at large. Through a complex system of meaning making, the knowledge accrued by illiterate adults is qualitatively different, and examining these differences in terms of their correlation to coping mechanisms developed in the face of social alienation and diminished professional prospects yields a greater understanding of class privilege and how nontraditional learners fit into a larger social structure. From the perspective of academic feminism, adult …

Victims Of More Than Just Bias Gender's Influence On Jury Awards And Other Monetary Benefits In Workplace Sexual Harassment Claims, Anthony Ferraro

HIM 1990-2015

The main objective in this research was to examine the extent to which gender and gender biases influence monetary benefits received, including jury award amounts, in workplace sexual harassment claims. Two methods were utilized to explore the discrepancies in monetary benefits received based on gender differences. The first method used was a survey to test various gender attitudes, attitudes on sexual harassment, and how influential a victim's gender was on determinations of damage award amounts in sexual harassment cases. 6 two-way factorial univariate between-subject analyses of variance (ANOVAs) were used to analyze the survey data. The second method in this …

The Role Tax Preparers Play In Taxpayer Compliance: An Empirical Investigation With Policy Implications, Sagit Leviner

Buffalo Law Review

No abstract provided.

Taking Balance Measurement Out Of The Laboratory And Into The Home: Discriminatory Capability Of Novel Centre Of Pressure Measurement In Fallers And Non-Fallers, Denise Mcgrath, Emer P. Doheny, Lorcan Walsh, David Mckeown, Clodagh Cunningham, Lisa Crosby, Rose Anne Kenny, Nikolaos Stergiou, Brian Caulfield, Barry R. Greene

Journal Articles

We investigated three methods for estimating centre of pressure excursions, as measured using a portable pressure sensor matrix, in order to deploy similar technology into the homes of older adults for longitudinal monitoring of postural control and falls risk. We explored the utility of these three methods as markers of falls risk in a cohort of 120 community dwelling older adults with and without a history of falls (65 fallers, 55 non-fallers). A number of standard quantitative balance parameters were derived using each centre of pressure estimation method. Rank sum tests were used to test for significant differences between fallers …

Frequency Of Poor Quality Of Life And Predictors Of Health Related Quality Of Life In Cirrhosis At A Tertiary Care Hospital Pakistan, Om Parkash, Romaina Iqbal, Fatima Jafri, Iqbal Azam, Wasim Jafri

Section of Gastroenterology

Background

Cirrhosis produces variety of symptoms which eventually lead to a negative impact on Health Related Quality of Life (HRQOL). The general aim of this study was to evaluate the magnitude of poor HRQOL and to assess factors related with HRQOL in patients with CLD in Pakistan.

Findings

This was a cross sectional study conducted in gastroenterology outpatient clinics of Aga Khan University Hospital, Karachi on adult patients with cirrhosis. In this study chronic liver disease questionnaire (CLDQ) was used to assess HRQOL of these patients and CLDQ score was used as an outcome measure to determine factors related with …

Generation Of Tanapoxvirus Ankyrin Repeat Gene Deletion Mutant For Evaluating Its Role In Cell Tropism, Yogesh Suryawanshi

Masters Theses

The host range of poxviruses is highly regulated and is limited to certain hosts. A number of genes in different poxviruses have been identified that contribute to cell tropism. The ankyrin (ANK) repeat genes encode for proteins characterized by the repetitive motifs in its amino acid sequence. These genes have been found to play a role in determining the ability of poxviruses to replicate in certain cell types. Tanapoxvirus (TPV) Kenya genome analysis indicated the presence of six ANK repeat genes of which T146R, T147R and T148R are present in the terminal part of the TPV-Kenya genome. To understand the …

En Route Towards Α-Benzotriazoyl Nitroso Derivatives, Jean-Christophe M. Monbaliu, Lucas K. Beagle, Judit K. Beagle, Matthias Zeller, Christian V. Stevens, Alan R. Katritzky

Chemistry Faculty Publications

A new class of geminally-substituted nitroso compounds, i.e., α-benzotriazoyl nitroso derivatives, is presented. These compounds display a rather different behavior than other related nitroso compounds bearing a geminal electron-withdrawing group. An unexpected and spontaneous oxidation to the nitro analog is observed in solution.

Characterization Of An Advanced Neuron Model, Christopher Echanique

HIM 1990-2015

This thesis focuses on an adaptive quadratic spiking model of a motoneuron that is both versatile in its ability to represent a range of experimentally observed neuronal firing patterns as well as computationally efficient for large network simulation. The objective of research is to fit membrane voltage data to the model using a parameter estimation approach involving simulated annealing. By manipulating the system dynamics of the model, a realizable model with linear parameterization (LP) can be obtained to simplify the estimation process. With a persistently excited current input applied to the model, simulated annealing is used to efficiently determine the …

Entering Collegiate Women's Decision To Discontinue Particpation In Sports: A Qualitative Study, Emily Gilliam

Health, Human Performance and Recreation Undergraduate Honors Theses

This study was conducted to gather information about why collegiate women discontinue participation in sports. Women at a Midwestern Division III institution participated in this study. Three groups of women were interviewed through focus groups: women no longer playing a sport, women currently playing collegiate athletics, and a mix of women currently playing a college sport and women no longer involved. The women were asked questions about sport involvement and answered collectively. Women provided responses that fell into 5 main categories: psychological, physical, educational, social, and attachment. Physical responses were those that dealt with health issues; some felt that the …

Statistical Clustering Of Microseismic Event Spectra To Identify Subsurface Structure, Deborah Kay Fagan

Boise State University Theses and Dissertations

Understanding subsurface structure by studying microseismicity influences a wide range of activities, including energy extraction, aquifer storage, carbon sequestration, and seismic hazard assessment. Identifying individual fractures in a larger fault system is key to characterizing, understanding, and potentially mitigating risks of natural or induced seismicity.

A year-long study associated with a carbon dioxide (CO₂) sequestration project was conducted at the Aneth oil field in southeast Utah to record microseismicity at a single downhole geophone array. A previous analysis located events by first identifying event multiplets consisting of highly correlated time-domain waveforms on receivers shallower than the depth of …

Dockomatic: An Emerging Resource To Manage Molecular Docking, Reed B. Jacob

Boise State University Theses and Dissertations

The application of computational modeling to rationally design drugs and characterize macro-biomolecular receptors has proven increasingly useful due to the accessibility of computing clusters and clouds. AutoDock is a well-known and powerful software program used to model ligand to receptor binding interactions. A limitation of AutoDock is the inability of a user to automatically create ligands and manage the input and output of data when dealing with large numbers of simulations; a problem that arises in High Throughput Virtual Screening (HTVS) or Inverse Virtual Screening (IVS). We have designed DockoMatic, a user friendly Graphical User Interface (GUI) application that constructs …

A Preclinical Investigation Of The Saturation And Dosimetry Of 153sm-Dotmp As A Bone-Seeking Radiopharmaceutical, Jaime Simon, Keith Frank, Druce K. Crump, William D. Erwin, Naoto T. Ueno, Richard E. Wendt Phd

Imaging Physics Journal Articles

Simón J, Frank RK, Crump DK, Erwin WD, Ueno NT, Wendt RE. A preclinical investigation of the saturation and dosimetry of 153Sm-DOTMP as a bone-seeking radiopharmaceutical. Nuclear Medicine and Biology. 2012/08/01/ 2012;39(6):770-776. doi:https://doi.org/10.1016/j.nucmedbio.2011.12.015

Insights On Cytochrome P450 Enzymes And Inhibitors Obtained Through Qsar Studies, Jayalakshmi Sridhar, Jiawang Liu, Maryam Foroozesh, Cheryl Stevens L. Klein Stevens

Faculty and Staff Publications

The cytochrome P450 (CYP) superfamily of heme enzymes play an important role in the metabolism of a large number of endogenous and exogenous compounds, including most of the drugs currently on the market. Inhibitors of CYP enzymes have important roles in the treatment of several disease conditions such as numerous cancers and fungal infections in addition to their critical role in drug-drug interactions. Structure activity relationships (SAR), and three-dimensional quantitative structure activity relationships (3D-QSAR) represent important tools in understanding the interactions of the inhibitors with the active sites of the CYP enzymes. A comprehensive account of the QSAR studies on …

The Real-Time Measurements Of Blood Nitric Oxide (No) And Hydrogen Peroxide (H2o2) Levels Under Acute Hyperglycemia, Michael Minni

PCOM Biomedical Studies Student Scholarship

Vascular endothelial dysfunction is one of the earliest recognizable events under hyperglycemic conditions. It is characterized by decreased endothelium-derived nitric oxide (NO) bioavailability and increased oxidative stress, such as superoxide and hydrogen peroxide (H₂O₂) overproduction. However, the real-time changes in blood NO and H₂O₂ levels under acute hyperglycemia have not been evaluated. In this study, acute hyperglycemia (200 mg/dl, 400 mg/dL, and 600 mg/dL) was induced by intravenous infusion of 20%, 30%, and 50% D-glucose respectively for 180 min. Infusion of saline or 30% L-glucose serve as controls. Blood NO or H_{2 …}

The Problem Of Data, Lori Jahnke, Andrew Asher, Spencer D.C. Keralis

Other Faculty Research and Publications

Jahnke and Asher explore workflows and methodologies at a variety of academic data curation sites, and Keralis delves into the academic milieu of library and information schools that offer instruction in data curation. Their conclusions point to the urgent need for a reliable and increasingly sophisticated professional cohort to support data-intensive research in our colleges, universities, and research centers.

Child Parent Relationship Therapy For Parents Of Children With Disruptive Behavior, Alison Moses

Dissertations

Young children who display extreme levels of disruptive behaviors are at increased risk for later academic difficulties, poor social relationships and adolescent delinquency, making early intervention efforts a priority. Studies evaluating Child-Parent Relationship Therapy (CPRT) have demonstrated its effectiveness in improving parental empathy, improving parental acceptance, decreasing parenting stress, and decreasing perceived child problem behavior. These outcomes, however, must be evaluated in light of several research limitations (e.g., lack of randomization, use of non-standardized measures, lack of treatment integrity data). Well conducted studies that assess the effectiveness of CPRT on specific presenting problems are needed to evaluate better the impact, …

Marital Quality, Acculturation, And Communication In Mexican American Couples, Audrey Lyn Schwartz

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Marital quality is a broad measurement of perceptions of satisfaction, happiness, and stability by partners in an established relationship. Marital quality has been relatively understudied among Mexican Americans, a population that warrants the inclusion of cultural constructs in any model concerning relationship outcomes. Therefore, acculturation differences between Mexican American couples were conceptualized as a distal context for understanding marital quality. Traditional gender role values and communication style (warmth and hostility) were included as proximal contexts. Data from Conger’s California Families Project were utilized; results indicated that while most measures of acculturation did not impact marital quality, language use interacted with …

An Exploration Of The Relationships Among Connectedness To Nature, Quality Of Life, And Mental Health, Peter G. Tauber

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In recent decades, a new branch of psychology has emerged—ecopsychology. This field looks at the complex relationship between human beings and the natural world. Previous research has shown the importance of direct experiences in nature for the promotion of human health and well-being. However, it is still not understood why these experiences in nature carry so much importance.

It is possible that the concept of connectedness to nature (CTN) plays a role in this relationship between nature and wellness. CTN is defined as feelings of close affiliation with the natural world in a physical, cognitive, and emotional manner. Previous research …

Waste Heat Utilization In An Anaerobic Digestion System, Brett Boissevain

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Anaerobic digestion has great potential as an energy source. Not only does it provide an effective method for waste mitigation, but it has the potential to generate significant quantities of fuel and electricity. In order to ensure efficient digestion and biomass utilization, however, the system must be continuously maintained at elevated temperatures. It is technically feasible to supplement such a system with outside energy, but it is more cost effective to heat the system using only the produced biogas. While there is considerable literature covering the theory of anaerobic digestion, there are very few practical studies to show how heat …