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Emu Today, October 15, 2012, Eastern Michigan University

EMU Today

No abstract provided.

Use Of Real-Time Pcr To Detect Surimi Adulteration In Vegetarian Foods, Ching-Yang Cheng, Yeu-Ching Shi, Sin-Rong Lin, Chi-Chiang Chou, Chin-Cheng Huang

Journal of Marine Science and Technology–Taiwan

Vegetarian foods are abundant in the domestic market. It is found that animal ingredients have been added into vegetarian products to improve the texture and taste. Surimi adulteration in vegetarian food is an area of concern for vegetarians. The α-skeletal actin gene of aquatic animals as novel specific primers and probe of Actinopterygii in 36 fish species are tested using real-time PCR method. It was found that all of the 36 fish species of Actinopterygii showed positive results. The 10 surimi products, 10 surimi-based products containing fish components showed positive results. All of the 10 fresh foods containing no fish …

College Of Education News, College Of Education, Georgia Southern University

College of Education: News & Publications (2003-2023)

• STEM Institute Names Affiliates, Includes 13 COE Faculty

Cysteine 904 Is Required For Maximal Insulin Degrading Enzyme Activity And Polyanion Activation, Eun Suk Song, Manana Melikishvili, Michael G. Fried, Maria A. Juliano, Luiz Juliano, David W. Rodgers, Louis B. Hersh

Molecular and Cellular Biochemistry Faculty Publications

Cysteine residues in insulin degrading enzyme have been reported as non-critical for its activity. We found that converting the twelve cysteine residues in rat insulin degrading enzyme (IDE) to serines resulted in a cysteine-free form of the enzyme with reduced activity and decreased activation by polyanions. Mutation of each cysteine residue individually revealed cysteine 904 as the key residue required for maximal activity and polyanion activation, although other cysteines affect polyanion binding to a lesser extent. Based on the structure of IDE, Asn 575 was identified as a potential hydrogen bond partner for Cys904 and mutation of this residue also …

Bjc Today

BJC Today

No abstract provided.

October 15, 2012 Aasu Faculty Senate Agenda, Armstrong State University

Armstrong Faculty Senate: Armstrong Faculty Senate Agenda (Archived)

October 15, 2012 AASU Faculty Senate Agenda

The Bg News October 15, 2012, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. October 15, 2012. Volume 103-Issue 25.

Differential Mitochondrial Toxicity Screening And Multi- Parametric Data Analysis, Maria V. Tsiper, Jennifer Sturgis, Larisa V. Avramova, Shilpa Parakh, Raymond Fatig, Ana Juan-García, Nianyu Li, Bartek Rajwa, Padma Narayanan, C. W. Wualls Jr., Joseph P. Robinson, Vincent J. Davisson

Weldon School of Biomedical Engineering Faculty Publications

Early evaluation of new drug entities for their potential to cause mitochondrial dysfunction is becoming an important task for drug development. Multi-parametric high-content screening (mp-HCS) of mitochondrial toxicity holds promise as a lead in-vitro strategy for drug testing and safety evaluations. In this study, we have developed a mp-HCS and multi-parametric data analysis scheme for assessing cell responses to induced mitochondrial perturbation. The mp-HCS measurements are shown to be robust enough to allow for quantitative comparison of biological systems with different metabolic pathways simulated by alteration of growth media. Substitution of medium glucose for galactose sensitized cells to drug action …

Quantifying The Cdk Inhibitor Vmy-1-103'S Activity And Tissue Levels In An In Vivo Tumor Model By Lc-Ms/Ms And By Mri., Paul Sirajuddin, Sudeep Das, Lymor Ringer, Olga C Rodriguez, Angiela Sivakumar, Yi-Chien Lee, Aykut Üren, Stanley T Fricke, Brian Rood, Alpay Ozcan, Sean S Wang, Sana Karam, Venkata Yenugonda, Patricia Salinas, Emanuel Petricoin, Michael Pishvaian, Michael P Lisanti, Yue Wang, Richard Schlegel, Bahram Moasser, Chris Albanese

Kimmel Cancer Center Faculty Papers

The development of new small molecule-based therapeutic drugs requires accurate quantification of drug bioavailability, biological activity and treatment efficacy. Rapidly measuring these endpoints is often hampered by the lack of efficient assay platforms with high sensitivity and specificity. Using an in vivo model system, we report a simple and sensitive liquid chromatography-tandem mass spectrometry assay to quantify the bioavailability of a recently developed novel cyclin-dependent kinase inhibitor VMY-1-103, a purvalanol B-based analog whose biological activity is enhanced via dansylation. We developed a rapid organic phase extraction technique and validated wide and functional VMY-1-103 distribution in various mouse tissues, consistent with …

Soil Nematodes And Their Prokaryotic Prey Along An Elevation Gradient In The Mojave Desert (Death Valley National Park, California, Usa), Amy M. Treonis, Kelsey Sutton, Brendan Kavanaugh, Archana Narla, Timothy Mcllarky, Jasmine Felder, Cecilia O'Leary, Megan Riley, Alyxandr Pikus, Sarah Thomas

Biology Faculty Publications

We characterized soil communities in the Mojave Desert across an elevation gradient. Our goal was to test the hypothesis that as soil quality improved with increasing elevation (due to increased productivity), the diversity of soil prokaryotes and nematodes would also increase. Soil organic matter and soil moisture content increased with elevation as predicted. Soil salinity did not correlate to elevation, but was highest at a mid-gradient, alluvial site. Soil nematode density, community trophic structure, and diversity did not show patterns related to elevation. Similar results were obtained for diversity of bacteria and archaea. Relationships between soil properties, nematode communities, and …

Effect Of Mulberry Lees Addition On The Quality Of Bread And Anthocyanin Content, Jean-Yu Hwang, Wen-Chieh Sung

Journal of Marine Science and Technology–Taiwan

Mulberry lees were added to bread dough at levels of 10%, 20%, and 30%. Loaves were prepared using the straight dough procedure. Bread volume, crust and crumb color, crumb texture, flavor and overall acceptability were evaluated. Anthocyanin content of crumbs was determined for 5 days storage duration. The volume of bread was decreased (p < 0.05) as the mulberry lees addition amount increased. Overall acceptability of 10% mulberry lees addition bread was highest among all breads. There was no significant difference in crumb texture except the firmness of 30% mulberry lees addition was higher than other groups. Addition of mulberry lees increased the anthocyanin content of crumb. Oxidation of anthocyanin occurs in crumbs during storage. Mulberry lees could be added to bread within 20% level for enhancing the nutritional quality and characteristics of bread.

Optimal Dynamic Temporal-Spatial Paramter Inversion Methods For The Marine Integrated Element Water Quality Model Using A Data-Driven Neural Network, Ming-Chang Li, Shu-Xiu Liang, Zhao-Chen Sun, Guang-Yu Zhang

Journal of Marine Science and Technology–Taiwan

Certain marine water quality or ecosystem model parameters vary in space and time because of different plankton taxonomic compositions over a large domain. The same parameter vectors can result in suboptimal calibration. In the present paper, a data-driven model based on an artificial neural network is developed to inverse the values of model parameters dynamically. All training data used are calculated using numerical water quality models from the results of multiparameter matching design cases such that physical properties are not disturbed. The aim is to determine the relationship between the model parameters and the pollution concentration values of interior stations. …

Idiosyncratic Responses Of Seagrass Phenolic Production Following Sea Urchin Grazing, Latina Steele, John F. Valentine

Biology Faculty Publications

While chemical defenses can determine plant persistence in terrestrial ecosystems and some marine macroalgae, their role in determining seagrass persistence in areas of intense grazing is unknown. As a first step toward determining if concentrations of feeding deterrents in seagrasses increase following herbivore attacks, we conducted 4 experiments using a common macrograzer (sea urchin Lytechinus variegatus) and 2 phylogenetically divergent seagrass species (Thalassia testudinum and Halodule wrightii). Macrograzer impacts on production of phenolic acids and condensed tannins varied somewhat idiosyncratically with season, urchin density, and distance from urchin damage. In general, phenolic concentrations were higher in both turtlegrass and shoalgrass …

October 15, 2012 Aasu Faculty Senate Minutes, Armstrong State University

Armstrong Faculty Senate: Minutes (Archived)

October 15, 2012 AASU Faculty Senate Minutes

Teaching As A Reflective Practice: Orgasmial Theory And Its Refutation, William Culver

MA TESOL Collection

An interdisciplinary study examining teaching as a reflective practice with special emphasis on expanding the underlying factors of constructing and maintaining an empowering learning environment, as well as the need for and development of “transformative integrity” as part of a proactive teaching praxis.

Unh Statement On Death Of Elizabeth 'Lizzi' Marriott, Erika Mantz

Media Relations

No abstract provided.

New Autonomous Motors Of Metal-Organic Framework (Mof) Powered By Reorganization Of Self-Assembled Peptides At Interfaces, Yasuhiro Ikezoe, Gosuke Washino, Takashi Uemura, Susumu Kitagawa, Hiroshi Matsui

Publications and Research

There have developed a variety of microsystems that harness energy and convert it to mechanical motion. Here we developed new autonomous biochemical motors by integrating metal-organic framework (MOF) and self-assembling peptides. MOF is applied as an energy-storing cell that assembles peptides inside nanoscale pores of the coordination framework. The robust assembling nature of peptides enables reconfiguring their assemblies at the water-MOF interface, which is converted to fuel energy. Re-organization of hydrophobic peptides could create the large surface tension gradient around the MOF and it efficiently powers the translation motion of MOF. As a comparison, the velocity of normalized by volume …

The Impact Of Covariance Misspecification In Multivariate Gaussian Mixtures On Estimation And Inference: An Application To Longitudinal Modeling, Brianna C. Heggeseth, Nicholas P. Jewell

U.C. Berkeley Division of Biostatistics Working Paper Series

Multivariate Gaussian mixtures are a class of models that provide a flexible parametric approach for the representation of heterogeneous multivariate outcomes. When the outcome is a vector of repeated measurements taken on the same subject, there is often inherent dependence between observations. However, a common covariance assumption is conditional independence---that is, given the mixture component label, the outcomes for subjects are independent. In this paper, we study, through asymptotic bias calculations and simulation, the impact of covariance misspecification in multivariate Gaussian mixtures. Although maximum likelihood estimators of regression and mixing probability parameters are not consistent under misspecification, they have little …

Blog Post, Bill Hogarth On Helping Our Distinguished Faculty, 'Burg Blogs, October 12, 2012, Bill Hogarth

USF St. Petersburg Campus News and Press Releases

A blog post by Interim Regional Chancellor Bill Hogarth of the University of South Florida St. Petersburg about the Internal Awards Program to provide seed money for faculty research.

Reporter - October 12th 2012, Rit Reporter Staff

University Publications

No abstract provided.

Cross-Ontology Multi-Level Association Rule Mining In The Gene Ontology., Prashanti Manda, Seval Ozkan, Hui Wang, Fiona M. Mccarthy, Susan M. Bridges

BCoE Publications

The Gene Ontology (GO) has become the internationally accepted standard for representing function, process, and location aspects of gene products. The wealth of GO annotation data provides a valuable source of implicit knowledge of relationships among these aspects. We describe a new method for association rule mining to discover implicit co-occurrence relationships across the GO sub-ontologies at multiple levels of abstraction. Prior work on association rule mining in the GO has concentrated on mining knowledge at a single level of abstraction and/or between terms from the same sub-ontology. We have developed a bottom-up generalization procedure called Cross-Ontology Data Mining-Level by …

Cross-Ontology Multi-Level Association Rule Mining In The Gene Ontology., Prashanti Manda, Seval Ozkan, Hui Wang, Fiona M. Mccarthy, Susan M. Bridges

FWRC Publications

The Gene Ontology (GO) has become the internationally accepted standard for representing function, process, and location aspects of gene products. The wealth of GO annotation data provides a valuable source of implicit knowledge of relationships among these aspects. We describe a new method for association rule mining to discover implicit co-occurrence relationships across the GO sub-ontologies at multiple levels of abstraction. Prior work on association rule mining in the GO has concentrated on mining knowledge at a single level of abstraction and/or between terms from the same sub-ontology. We have developed a bottom-up generalization procedure called Cross-Ontology Data Mining-Level by …

Flyer News, Vol. 60, No. 10 (Oct. 12, 2012), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Alumna Wins Bartholomew Award, Mallika Kavadi '15

News and Events (Discontinued Series)

No abstract provided.

Phytoplankton Responses To Atmospheric Metal Deposition In The Coastal And Open-Ocean Sargasso Sea, Katherine Mackey, Kristen N. Buck, John Casey, Abigail Cid, Michael Lomas, Yoshiki Sohrin, Adina Paytan

Marine Science Faculty Publications

This study investigated the impact of atmospheric metal deposition on natural phytoplankton communities at open-ocean and coastal sites in the Sargasso Sea during the spring bloom. Locally collected aerosols with different metal contents were added to natural phytoplankton assemblages from each site, and changes in nitrate, dissolved metal concentration, and phytoplankton abundance and carbon content were monitored. Addition of aerosol doubled the concentrations of cadmium (Cd), cobalt (Co), copper (Cu), iron (Fe), manganese (Mn), and nickel (Ni) in the incubation water. Over the 3-day experiments, greater drawdown of dissolved metals occurred in the open ocean water, whereas little metal drawdown …

Volume Cxxx, Number 5, October 12, 2012, Lawrence University

The Lawrentian

No abstract provided.

Amp-Activated Protein Kinase Stimulates Myostatin Expression In C2c12 Cells, Arun K. Das, Qi Yuan Yang, Xing Fu, Jun Fang Liang, Marcio S. Duarte, Mei Jun Zhu, Grant D. Trobridge, Min Du

Faculty Publications

AMP-activated protein kinase (AMPK) is a master regulator of energy metabolism in skeletal muscle; AMPK induces muscle protein degradation but the underlying mechanisms are unclear. Myostatin is a powerful negative regulator of skeletal muscle mass and growth in mammalian species. We hypothesized that AMPK stimulates myostatin expression, which provides an explanation for the negative role of AMPK in muscle growth. The objective of this study is to demonstrate that AMPK stimulates myostatin expression using C2C12 cells as a model. Activation of AMPK by 5-aminoimidazole-4-carboxamide-1-β- d-riboruranoside (AICAR.) dramatically increased the mRNA expression and protein content of myostatin in C2C12 myotubes, and …

Today - October 19, 2012, Loma Linda University

TODAY

Inside this issue:

-- Nearly 11,000 march to support cancer patients at 5th annual Believe Walk
-- Local charitable gifts fund new equipment and research at LLU Cancer Center
-- California governor appoints dental faculty member to committee
-- San Manuel Band of Mission Indians gift helps cancer patient defeat his disease
-- ABC News names LLU No. 1 for graduate starting salaries in nation
-- School of Public Health creates environmental health training for Latinos
-- School of Pharmacy relocates to Shryock
-- LLU professor returns to Utah to study geological features from biblical worldview
-- Country singer brightens …

Emu Today, October 12, 2012, Eastern Michigan University

EMU Today

No abstract provided.

Agenda And Minutes, University Of South Florida St. Petersburg General Education Committee Meeting, October 12, 2012, University Of South Florida St. Petersburg. Faculty Senate. General Education Committee

USF St. Petersburg General Education Committee Meetings

Agenda and minutes from the October 12, 2012, meeting of the General Education Committee of the University of South Florida St. Petersburg's Faculty Senate.