Digital Commons Network^™

Sea-Level Rise And Its Impact On Vulnerable States: Four Examples, Ann Powers

Louisiana Law Review

No abstract provided.

Reasonable Men?, Ann C. Mcginley

Scholarly Works

After the Supreme Court recognized sexual harassment as a form of sex discrimination under Title VII, lower courts used the reasonable person standard to measure whether the behavior was sufficiently severe or pervasive to constitute a hostile working environment. Cultural and radical feminists objected to the reasonable person measure, and many supported a reasonable woman standard, which the Ninth Circuit adopted. Because of its tendency to essentialize how women would react, many feminists soon abandoned their support for the standard. A number of circuits, however, continue to use the reasonable woman or reasonable victim standards.

Most of the scholarship concerning …

Longitudinal Documentation Of Serum Cartilage Oligomeric Matrix Protein And Patient-Reported Outcomes In Collegiate Soccer Athletes Over The Course Of An Athletic Season, Johanna M. Hoch, Carl G. Mattacola, Heather M. Bush, Jennifer M. Medina Mckeon, Timothy E. Hewett, Christian Lattermann

Physical Therapy Faculty Publications

BACKGROUND: Serum cartilage oligomeric matrix protein (sCOMP) is a biomarker for cartilage degradation. Patient-reported outcomes (PRO) are used to document postinjury recovery and may be used to prospectively identify changes in the course of a season. It is unknown what effect intense, continuous physical activity has on sCOMP levels and PRO values in athletes over the duration of a soccer season.

HYPOTHESIS/PURPOSE: The purpose of this study was to longitudinally document sCOMP levels and to determine whether changes in PROs occur in collegiate soccer athletes during a season. The hypotheses tested were that sCOMP levels and PRO scores would remain …

Quality And Nutritional Status Of Fresh-Cut Tomato As Affected By Spraying Of Delactosed Whey Permeate Compared To Industrial Washing Treatment., Lubna Ahmed, Ana Belen Martin-Diana, Daniel Rico, Catherine Barry-Ryan

Articles

The aim of this study was to examine the applicability of delactosed whey permeate 28 (DWP) treatment on preserving the quality and antioxidant attributes of fresh-cut 29 tomato. Tomatoes were treated with 3 % DWP by dipping, spraying and a 30 combination of both, stored at 4 °C for 10 days and compared with the industrial 31 standard, chlorine. The combination of dipping and spraying of DWP showed the best 32 results for all the markers tested. The combined treatment of dipping and spraying of 33 DWP significantly lowered total counts (~ 1.0 log cfu/g), yeast and moulds (~ 1.2 …

Structural Insights Into The Inhibition Of Actin-Capping Protein By Interactions With Phosphatidic Acid And Phosphatidylinositol (4,5)-Bisphosphate., Roman Pleskot, Premysl Pejchar, Viktor Zarsky, Christopher J. Staiger, Martin Potocky

Department of Biological Sciences Faculty Publications

The actin cytoskeleton is a dynamic structure that coordinates numerous fundamental processes in eukaryotic cells. Dozens of actin-binding proteins are known to be involved in the regulation of actin filament organization or turnover and many of these are stimulus-response regulators of phospholipid signaling. One of these proteins is the heterodimeric actin-capping protein (CP) which binds the barbed end of actin filaments with high affinity and inhibits both addition and loss of actin monomers at this end. The ability of CP to bind filaments is regulated by signaling phospholipids, which inhibit the activity of CP; however, the exact mechanism of this …

The Transcription Factor Gli1 Mediates Tgfb1 Driven Emt In Hepatocellular Carcinoma Via A Snai1-Dependent Mechanism, Sherine F. Elsawa, Xin Zheng, Natalia B. Rumie Vittar, Xiaohong Gai, Maite G. Fernandez-Barrena, Catherine D. Moser, Chunling Hu, Luciana L. Almada, Angela L. Mccleary-Wheeler, Anne M. Vrabel, Abdirashid M. Shire, Andrea Comba, Snorri S. Thorgeirsson, Youngsoo Kim, Qingguang Liu, Martin E. Fernandez-Zapico, Lewis R. Roberts

Faculty Articles, Papers, and Other Scholarship

The role of the epithelial-to-mesenchymal transition (EMT) during hepatocellular carcinoma (HCC) progression is well established, however the regulatory mechanisms modulating this phenomenon remain unclear. Here, we demonstrate that transcription factor glioma-associated oncogene 1 (GLI1) modulates EMT through direct up-regulation of SNAI1 and serves as a downstream effector of the transforming growth factor-b1 (TGFb1) pathway, a well-known regulator of EMT in cancer cells. Overexpression of GLI1 increased proliferation, viability, migration, invasion, and colony formation by HCC cells. Conversely, GLI1 knockdown led to a decrease in all the above-mentioned cancer-associated phenotypes in HCC cells. Further analysis of GLI1 regulated cellular functions showed …

Collecting To The Core — Psychology Handbooks, Donald J. Polzella, Anne Doherty

Psychology Faculty Publications

The American Psychological Association (APA), which publishes several specialized handbooks, describes them as “one-stop shop[s] for both overviews and in-depth analyses of a variety of sub-fields within psychology.” In general, upper-level undergraduates, graduate students, and faculty scholars consult handbooks for different reasons. Upper-level undergraduate and graduate students sometimes read handbook chapters for a course or seminar. (In my experience, most lower-level undergraduates find the style and content of handbook chapters bewildering.) Undergraduate honors students and, especially, graduate students may consult handbook chapters when they begin to work on their theses or dissertations, because the chapters provide authoritative reviews of relevant …

Monte Carlo Simulations Of The Clean And Disordered Contact Process In Three Dimensions, Thomas Vojta

Physics Faculty Research & Creative Works

The absorbing-state transition in the three-dimensional contact process with and without quenched randomness is investigated by means of Monte Carlo simulations. In the clean case, a reweighting technique is combined with a careful extrapolation of the data to infinite time to determine with high accuracy the critical behavior in the three-dimensional directed percolation universality class. In the presence of quenched spatial disorder, our data demonstrate that the absorbing-state transition is governed by an unconventional infinite-randomness critical point featuring activated dynamical scaling. The critical behavior of this transition does not depend on the disorder strength, i.e., it is universal. Close to …

Admission Criteria To Saudi Medical Schools. Which Is The Best Predictor For Successful Achievement?, Jamal A. Albishri, Syed M. Aly, Yasir Alnemary

Saudi Medical Journal

OBJECTIVE: To assess the relationship between current pre-admission criteria and medical student9s grade point average (GPA) at the end of year 6 in 3 medical schools in the Kingdom of Saudi Arabia. METHODS: We conducted this observational analytical study at 3 government medical schools in the Kingdom of Saudi Arabia between January 2011 and February 2012. High school grades, achievement test (Tahsili test) scores, aptitude test (Qudraat tests) scores, Mathematics, and English grades in the high school were used to predict medical student9s GPA at the end of year 6. The criterion variable was student9s cumulative GPA at the end …

Takotsubo Cardiomyopathy And Catatonia: An Acute Stress Connection?, Lex Denysenko, Md, Rachel Shmuts, Do, Adam Trenton, Do, Ethan J. Halpern, Md, Madeleine Becker, Md

Department of Psychiatry and Human Behavior Faculty Papers

BACKGROUND

•Takotsubo cardiomyopathy (TCM):

•transient left ventricular dysfunction

•ECG changes and symptoms mimicking acute MI

•often precipitated by emotional stressor

•Catatonia is a psychomotor syndrome most commonly seen in mood disorders

•This is the first known reported case of TCM co-occurring with catatonia in the setting of acute psychological trauma and bereavement

A Four Factor Model Of Systems-Based Practices In Psychiatry., Jules M. Ranz, Michael Weinberg, Melissa R. Arbuckle, Joanna Fried, Anthony Carino, Hunter L. Mcquistion, Glen Davis, Donovan Wong, Sosunmolu O. Shoyinka, Benjamin Brody, Kamala D. Sethi, Anna Skiandos, Wesley Sowers, David Stern, Anne Sullivan, Michael J. Vergare

Department of Psychiatry and Human Behavior Faculty Papers

No abstract provided.

Optimizing The Mechanical Characteristics Of Bamboo To Improve The Flexural Behavior For Biocomposite Structural Application, Jay Lopez

Master's Theses

Global awareness and preservation have spurred increasing interest in utilizing environmentally friendly materials for high-performance structural applications. Biocomposites pose an appealing solution to this issue and are characterized by their sustainable lifecycles, biodegradable qualities, light weight, remarkable strength, and exceptional stiffness. Many of these structural qualities are found in applications that exhibit flexural loading conditions, and this study focuses on improving the bending performance of engineered biocomposite structures. The current application of biocomposites is increasing rapidly, so this expanding research explores other natural constituent materials for biocomposite structures under flexural loading.

The renewable material investigated in this study was experimentally …

Docking System Design And Self-Assembly Control Of Distributed Swarm Flying Robots, Hongxing Wei, Ning Li, Yong Tao, Youdong Chen, Jindong Tan

Michigan Tech Publications, Part 1

This paper presents a novel docking system design and the distributed self-assembly control strategy for a Distributed Swarm Flying Robot (DSFR). The DSFR is a swarm robot comprising many identical robot modules that are able to move on the ground, dock with each other and fly coordinately once self-assembled into a robotic structure. A generalized adjacency matrix method is proposed to describe the configurations of robotic structures. Based on the docking system and the adjacency matrix, experiments are performed to demonstrate and verify the self-assembly control strategy.

The Analogous Constitutional Protection Of Race And Sexual Preference: Recognizing The Shared Vulnerability, Nancy K. Kubasek, M. Neil Browne, Robert D. Campbell

DePaul Journal for Social Justice

No abstract provided.

Nature And Function Of Insulator Protein Binding Sites In The Drosophila Genome, Yuri Schwartz, Daniela Linder-Basso, Peter Kharchenko, Michael Tolstorukov, Maria Kim, Hua-Bing Li, Andrey Gorchakov, Aki Minoda, Gregory Shanower, Artyom Alekseyenko, Nicole Riddle, Youngsook Jung, Tingting Gu, Annette Plachetka, Sarah C.R. Elgin, Mitzi Kuroda, Peter Park, Mikhail Savitsky, Gary Karpen, Vincenzo Pirrotta

Biology Faculty Research

Chromatin insulator elements and associated proteins have been proposed to partition eukaryotic genomes into sets of independently regulated domains. Here we test this hypothesis by quantitative genome-wide analysis of insulator protein binding to Drosophila chromatin. We find distinct combinatorial binding of insulator proteins to different classes of sites and uncover a novel type of insulator element that binds CP190 but not any other known insulator proteins. Functional characterization of different classes of binding sites indicates that only a small fraction act as robust insulators in standard enhancer-blocking assays. We show that insulators restrict the spreading of the H3K27me3 mark but …

Multifactorial Patterns Of Gene Expression In Colonic Epithelial Cells Predict Disease Phenotypes In Experimental Colitis, Aubrey Leigh Frantz, Maria E. C. Bruno, Eric William Rogier, Halide Tuna, Donald A. Cohen, Subbarao Bondada, Ralph Lakshman Chelvarajan, J. Anthony Brandon, C. Darrell Jennings, Charlotte S. Kaetzel

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Background— The pathogenesis of inflammatory bowel disease (IBD) is complex and the need to identify molecular biomarkers is critical. Epithelial cells play a central role in maintaining intestinal homeostasis. We previously identified five “signature” biomarkers in colonic epithelial cells (CEC) that are predictive of disease phenotype in Crohn's disease. Here we investigate the ability of CEC biomarkers to define the mechanism and severity of intestinal inflammation.

Methods— We analyzed the expression of RelA, A20, pIgR, tumor necrosis factor (TNF), and macrophage inflammatory protein (MIP)-2 in CEC of mice with dextran sodium sulfate (DSS) acute colitis or T-cell-mediated chronic colitis. …

Shifting Seas: The Law's Response To Changing Ocean Conditions, Casey Schickling

Sea Grant Law Fellow Publications

No abstract provided.

From Reflecting To Making: Psychology In A World Of Change, Kenneth J. Gergen

Psychology Faculty Works

No abstract provided.

Sea-Level Rise And The Endangered Species Act, Dave Owen

Louisiana Law Review

No abstract provided.

“Modern Day Canary In The Coal Mine”, John A. Crawford

The Confluence (2009-2020)

Salamanders serve an array of functions in the Missouri environment, as this primer on amphibians by John Crawford suggests.

Dysregulation Of Mir-31 And Mir-21 Induced By Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, Louise Fong

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Presented at: Hallmarks and Cancer Conference, October 29-31 in San Francisco.

And AICR Annual Meeting, November 1-2, 2012.

Dietary zinc (Zn) deficiency (ZD) in rats induces an inflammatory gene signature that fuels esophageal squamous cell cancer (ESCC). Using nanoStringTM technology, we show that the inflammation is accompanied by altered expression of specific microRNAs in esophagus, as well as skin, lung, pancreas, liver, prostate, and PBMC, predictive of disease development. Particularly, the ZD esophagus has a microRNA signature resembling human ESCC/tongue SCC miRNAomes with overexpression of miR-31 and miR-21 and downregulation of their respective tumor suppressor targets PPP2R2A and …

Anabolic And Androgenic Effects Of Certain Atriplex Species Grown In Egypt, Dina M. El-Kersh, Fatma S. El-Sakhawy, Dina R. Abou-Hussein, Amany A. Sleem

Pharmacy

20-Hydroxyecdysone (20-HE) was detected by TLC in the ethyl acetate fraction of two Atriplex species grown in Egypt: A. lindleyi subsp. inflata and A. leucoclada. EIA quantification of 20-HE proved its presence in a concentration of 9.15 and 7.3 μg/g dried aerial parts in each of the two species, respectively. Significant anabolic and androgenic activities were demonstrated for 20-HE comparing to testosterone; the study also revealed that the total alcohol extract and the ethyl acetate fraction of A. lindleyi subsp. inflata exhibited greater activities than their analogues in A. leucoclada. Column chromatographic fractionation of the ethyl acetate fraction of the …

My Experiment With The Flipped Classroom Model, Nancy Wootton Colborn

LOEX Quarterly

No abstract provided.

Phylogenetic Engineering Of The Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase Large Subunit In Chlamydomonas Reinhardtii, Boon Hoe Lim

Department of Biochemistry: Dissertations, Theses, and Student Research

Thirty-four residues in the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) may account for the kinetic differences between Rubisco enzyme from green algae and land plants. By substituting these "phylogenetic residues" as groups and combinations of groups in the large subunit of the green alga Chlamydomonas reinhardtii with those of land-plant Rubisco, the functions and relationships of these "phylogenetic groups" were determined.

A phylogenetic-group substitution at the base of catalytic loop 6 of the large subunit decreases the CO₂/O₂ specificity of the enzyme, but function is restored by a further phylogenetic-group substitution at the carboxy-terminal tail. Therefore, these …

Parental Perceptions Of School Quality : Contesting The Notion Of Quality, Dilshad Ashraf

Institute for Educational Development, Karachi

No abstract provided.

Noninvasive Optical Characterization Of Muscle Blood Flow, Oxygenation, And Metabolism In Women With Fibromyalgia, Yu Shang, Katelyn Gurley, Brock Symons, Douglas Long, Ratchakrit Srikuea, Leslie J. Crofford, Charlotte A. Peterson, Guoqiang Yu

Biomedical Engineering Faculty Publications

INTRODUCTION: Women with fibromyalgia (FM) have symptoms of increased muscular fatigue and reduced exercise tolerance, which may be associated with alterations in muscle microcirculation and oxygen metabolism. This study used near-infrared diffuse optical spectroscopies to noninvasively evaluate muscle blood flow, blood oxygenation and oxygen metabolism during leg fatiguing exercise and during arm arterial cuff occlusion in post-menopausal women with and without FM.

METHODS: Fourteen women with FM and twenty-three well-matched healthy controls participated in this study. For the fatiguing exercise protocol, the subject was instructed to perform 6 sets of 12 isometric contractions of knee extensor muscles with intensity steadily …

Excellent Teaching: A Collective Case Study Of Outstanding Elementary Mathematics Teachers' Teaching Of Mathematics, Michael J. Gay

College of Education and Human Sciences: Dissertations, Theses, and Student Research

This qualitative collective case study explored the mathematical teaching of three excellent elementary teachers who were nominated by experts in mathematics and mathematics educational organizations, agencies and universities. I examined what excellent elementary mathematics teachers know and do in their practice of teaching. The study depicts detailed verbatim interactions between the teachers and students during actual teaching episodes to give the reader naturalistic examples of the explanation patterns and questioning strategies that these excellent teachers used to further students’ understandings of mathematical concepts and procedures. Analyses of the pedagogical strategies, including the interactive exploratory problem solving format these teachers used, …

What Brings You Pleasure? The Role Of Desire Within The Development Of Compulsive Purchasing, Justine Rapp

College of Business: Dissertations, Theses, and Student Research

This paper seeks to put forth two major contributions into marketing scholarship: (1) the role of desire within the development of compulsivity from impulsive consumptions, and (2) an assessment of compulsivity measurement scales. A mixed method design provides for both statistical and qualitative support for both contributions, for a deeper and replicated account of consumer behavior within the marketplace. First, we develop a possible path for the development of compulsivity, explaining impulsivity as an antecedent with consumer shopping desire as the driving factor. With this, we introduce the variable Consumer Shopping Desire as a quantified construct related to Belk et …

Group Testing Regression Models, Boan Zhang

Department of Statistics: Dissertations, Theses, and Student Research

Group testing, where groups of individual specimens are composited to test for the presence or absence of a disease (or some other binary characteristic), is a procedure commonly used to reduce the costs of screening a large number of individuals. Statistical research in group testing has traditionally focused on a homogeneous population, where individuals are assumed to have the same probability of having a disease. However, individuals often have different risks of positivity, so recent research has examined regression models that allow for heterogeneity among individuals within the population. This dissertation focuses on two problems involving group testing regression models. …

Book Review Of The Collapse Of American Criminal Justice, By William J. Stuntz, Andrea Roth

Journal of Legal Education

No abstract provided.