Implementation Of Magnetic Resonance Elastography For The Investigation Of Traumatic Brain Injuries, Thomas Boulet

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

Magnetic resonance elastography (MRE) is a potentially transformative imaging modality allowing local and non-invasive measurement of biological tissue mechanical properties. It uses a specific phase contrast MR pulse sequence to measure induced vibratory motion in soft material, from which material properties can be estimated. Compared to other imaging techniques, MRE is able to detect tissue pathology at early stages by quantifying the changes in tissue stiffness associated with diseases. In an effort to develop the technique and improve its capabilities, two inversion algorithms were written to evaluate viscoelastic properties from the measured displacements fields. The first one was based on …

Motivation For Consumers Participating In A Sustainable Food System, Brittney Albin

Department of Environmental Studies: Undergraduate Student Theses

Currently there are trends for consumers to start choosing more sustainable options in every aspect of their life, including food. There are many negative consequences for both the environment and human health due to conventional industrial agricultural practices (Horrigan et al., 2002; Leitzman and Cannon, 2005). Sustainable agricultural practices are being promoted as part of a larger sustainable food system. As Leo Horrigan et al. describe it, “sustainable agriculture is not merely a package of prescribed methods. More important, it is a change in mindset whereby agriculture acknowledges its dependence on a finite natural resource base” (Horrigan et al., 2002: …

Taking Crime Out Of Crime Business, Mark James Findlay, Nafis Hanif

Research Collection Yong Pung How School Of Law

It is one thing to assert that conventional market analysis is critically useful in understanding criminal enterprise. It is more challenging to suggest that corrupt and compromised legal regulation interacts with other critical market variables to maximise market advantage for crime business in a similar manner to legitimate regulatory forces in their protection and enhancement of legitimate business enterprise. The central argument of this paper is that crime business mirrors other business forms when considered in terms of critical market variables, and that in particular regulatory forces when inverted from their original purposes can influence market conditions in the same …

Elucidation Of The Biosynthesis Of The Di-C-Glycosylflavone Isoschaftoside, An Allelopathic Component From Desmodium Spp. That Inhibits Striga Spp. Development, Mary L. Hamilton, Serge P. Kuate, Melissa Brazier-Hicks, John C. Caulfield, Ruth Rose, Robert Edwards, Baldwyn Torto, John A. Pickett, Antony M. Hooper

All Peer-Reviewed Publications

Isoschaftoside, an allelopathic di-C-glycosylflavone from Desmodium spp. root exudates, is biosynthesised through sequential glucosylation and arabinosylation of 2-hydroxynaringenin with UDP-glucose and UDP-arabinose. Complete conversion to the flavone requires chemical dehydration implying a dehydratase enzyme has a role in vivo to complete the biosynthesis. The C-glucosyltransferase has been partially characterised and its activity demonstrated in highly purified fractions. © 2012 Elsevier Ltd. All rights reserved.

Ideology In Popular Late Twentieth And Twenty-First Century Children's And Young Adult Literature And Film, Iris Grace Shepard

Graduate Theses and Dissertations

Texts created for the consumption of children and young adults are not simple texts made for the sole purpose of entertaining young audiences. In fact, these texts are complicated, multi-faceted texts that function both in the creation and performance of childhood. Children's and young adult literature and film disseminated mainstream ideology about young people's place in society and attempt to enculturate young readers and viewers in regards to race, gender, age, and Social class. However, by helping young people interact critically with these texts, critical thinking skills as well as a passion for reading can be fostered. In addition, by …

Breeding For Modified Seed Composition In Soybean: Selection Of Genotypes, Yield Stability, And Environmental Effects, Luciano Miguel Jaureguy

Graduate Theses and Dissertations

The development of cultivars with modified seed composition represents an excellent alternative to cope with the world's need for more nutritious food. Understanding the genetic and environmental factors controlling crop seed quality traits is of crucial importance for such an endeavor. The objectives of this study were: a) to evaluate the efficiency of phenotype and marker-assisted selection for low stachyose and low phytate soybean breeding lines, and their yield stability, b) to study the effect of management practices planting date and delayed harvest on soybean seed composition, and c) to study the potential association between soil properties and leaf chemical …

Taxonomy And Dna Barcoding In The Genus Manfreda (Salisb.) Asparagaceae, William David Ritchie

Graduate Theses and Dissertations

The genus Manfreda Salisb. of Asparagaceae is a genus of potential horticultural interest and is currently subject to breeding efforts at the University of Arkansas. A lack of taxonomic clarity however undermines the classification of potential inter - and intrageneric hybrids. The study aims to assess existing species delimitation within the genus Manfreda employing morphology while investigating the potential utility of Consortium for the Barcode of Life Plant (CBOL) DNA Barcodes for identification of specific taxa and an External Transcribed Spacer (ETS) - Internal Transcribed Spacer (ITS) DNA barcode for developed hybridized taxa.

Observation of 855 herbarium specimens facilitated phylogenetic …

Capillary And Microchip Electrophoresis For The Monitoring Of Disease Causing Amyloid Proteins, Elizabeth Nancy Pryor

Graduate Theses and Dissertations

The detection of oligomers and aggregates formed by two amyloid proteins, insulin and amyloid-beta (AB), is of particular importance due to the role which these species play in Diabetes and Alzheimer's disease, respectively. However, existing techniques are limited in the ability to detect insulin and AB; oligomers due to the fact that these early aggregates are transient, present at low concentrations, and difficult to isolate. Improvements must be made to existing techniques or alternative techniques must be explored in order to identify and quantify the size of these oligomeric and aggregate species without disrupting their structure.

Capillary and microchip electrophoresis …

Response Of Broiler Chickens To Variation In Dietary Nutrient Content, Sarah Diane Goodgame

Graduate Theses and Dissertations

Rising feed costs, environmental pollution concerns targeted at animal agriculture, a worldwide focus on sustainability and the never ending battle to improve production and efficiency within the poultry industry challenges nutritionists to focus on products to improve nutrient digestibility and decrease feed costs while at the same time maximizing performance. The research presented in this dissertation focuses on improving nutrient utilization of protein sources with protein liberating enzymes currently available commercially. The research also conducted addresses the addition of crystalline amino acids valine and isoleucine and their effect on improving efficiency of broilers.

The first research project compared the efficacy …

Diagenesis And Reservoir Characterization Of The Pennsylvanian Middle Atoka Formation, Sebastian And Logan Counties, West-Central Arkansas, Elvis Chekwube Bello

Graduate Theses and Dissertations

The Middle Atoka Formation evolved from a stable passive margin during the early Pennsylvanian time to a rapidly subsiding basin, with the sedimentary fill thickening greatly southward during the middle Pennsylvanian time. The basin dips in north-south direction. An east-west anticlines and synclines were observed.

The purpose of this study is to establish the stratigraphic units, reservoir geometry and distribution, and infer the depositional environments and reservoir quality. Well correlation and petrographic studies are used to achieve the goals.

Sandstone Point Count method was used. The Point Counts was divided into five categories. They include the framework grains (quartz, feldspar, …

Aesthetic Qualities Of Websites And Their Effects On Public Perceptions Of Agricultural Issues And Organizations, Chase Tyler Hundley

Graduate Theses and Dissertations

This study sought to evaluate perceptions of agricultural issues and organizations based on how information is presented visually in websites. Researchers intended the results to be used to help the agricultural industry more effectively communicate information through better website design and increased persuasiveness. The study was conducted through the use of three focus group sessions as mapped out by Krueger (1998a, 1998b, 1998c) and Morgan (1998a, 1998b). The study used non-agriculture students purposively selected from a class in the University of Arkansas School of Human Environmental Sciences as participants in the study. The subject demographics closely resembled the primary demographics …

The Impact Of Bovine Spongiform Encephalopathy (Bse) On World Protein Supply, Jarrod Kersey

Graduate Theses and Dissertations

As world population, per capita income and urbanization increase, consumption of meat, poultry, milk and eggs will continue to rise to meet the needs of approximately nine billion people in 2050. Global beef, pig and chicken production and per capita consumption increased between 2000 and 2010, with growth in broiler production and consumption outpacing both beef and swine. The increased production and consumption requires readily available feed ingredients in regions where animal production is rapidly developing. Animal-based protein feed ingredients are often difficult to move from country to country due to real or perceived risk of animal disease. Zoosanitary standards …

Evaluation Of The Recombination Efficiencies Of Flp Proteins, Linh Duy Nguyen

Graduate Theses and Dissertations

Site-specific recombination systems are powerful tools for genetic modification. They have been used to integrate a transgene into a pre-defined locus and to remove marker genes from a transgene locus. Two of the most widely used site-specific recombination systems in plants are the Cre/lox system from the bacteriophage P1 and the FLP/FRT system from the yeast Saccharomyces cerevisiae. The Cre/lox system is well-characterized and is the first choice in application of site-specific recombination system. However, some applications such as marker-free site-specific gene integration require the use of two recombination systems. In addition, the availability of alternative recombination systems can offer …

False Smut Of Rice: Histological Analysis Of Infection, Liem Thi Thanh Nguyen

Graduate Theses and Dissertations

False smut of rice, caused by Ustilaginoidea virens (Cooke) Takahashi (Teleomorph: Villosiclava virens), has become a common disease in most major rice growing regions throughout the world. Considerable confusion exists regarding the infection process and the disease cycle. Therefore, a clearer understanding of pathogenesis caused by Ustilaginoidea virens is critical for future efforts to develop genetic and chemical tools to manage false smut in Arkansas and other regions of the world. The overall goal of this research was to clarify the infection process underlying false smut, with emphasis on comparing and contrasting the histological basis of root and foliar infections. …

Documentation And Control Of Acetolactate Synthase-Resistant Barnyardgrass (Echinochloa Crus-Galli) In Arkansas Rice, Michael Joshua Wilson

Graduate Theses and Dissertations

Barnyardgrass, the most problematic grass weed of Arkansas rice, was found resistant to propanil in 1990, and since then, it has evolved resistance to quinclorac and clomazone. Barnyardgrass is now believed to have evolved resistance to acetolactate synthase (ALS)-inhibiting herbicides. The goal of this research was to confirm and determine the level of resistance of the putative resistant biotype to the ALS-inhibiting herbicides imazethapyr, bispyribac, and penoxsulam and to develop herbicide programs for controlling ALS-, propanil-, quinclorac-, and clomazone-resistant barnyardgrass. The lethal dose needed to kill 50% of the putative ALS-resistant plants was higher than that of the susceptible biotype …

Structural And Functional Analysis Of Multi-Interface Domains, Liang Zhao, Steven C. H. Hoi, Limsoon Wong, Tobias Hamp, Jinyan Li

Research Collection School Of Computing and Information Systems

A multi-interface domain is a domain that can shape multiple and distinctive binding sites to contact with many other domains, forming a hub in domain-domain interaction networks. The functions played by the multiple interfaces are usually different, but there is no strict bijection between the functions and interfaces as some subsets of the interfaces play the same function. This work applies graph theory and algorithms to discover fingerprints for the multiple interfaces of a domain and to establish associations between the interfaces and functions, based on a huge set of multi-interface proteins from PDB. We found that about 40% of …

Altered Hemodynamics, Endothelial Function, And Protein Expression Occur With Aortic Coarctation And Persist After Repair, Arjun Menon, Thomas J. Eddinger, Hongfeng Wang, David C. Wendell, Jeffrey M. Toth, John F. Ladisa

Biomedical Engineering Faculty Research and Publications

Coarctation of the aorta (CoA) is associated with substantial morbidity despite treatment. Mechanically induced structural and functional vascular changes are implicated; however, their relationship with smooth muscle (SM) phenotypic expression is not fully understood. Using a clinically representative rabbit model of CoA and correction, we quantified mechanical alterations from a 20-mmHg blood pressure (BP) gradient in the thoracic aorta and related the expression of key SM contractile and focal adhesion proteins with remodeling, relaxation, and stiffness. Systolic and mean BP were elevated for CoA rabbits compared with controls leading to remodeling, stiffening, an altered force response, and endothelial dysfunction both …

Assessing Retinal Structure In Complete Congenital Stationary Night Blindness And Oguchi Disease, Pooja Godara, Robert F. Cooper, Panagiotis I. Sergouniotis, Melissa A. Diederichs, Megan R. Streb, Mohamed Genead, J. Jason Mcanany, Andrew R. Webster, Anthony T. Moore, Adam M. Dubis, Maureen Neitz, Alfredo Dubra, Edwin M. Stone, Gerald A. Fishman, Dennis P. Han, Michel Michaelides, Joseph Carroll

Biomedical Engineering Faculty Research and Publications

Purpose

To examine retinal structure and changes in photoreceptor intensity after dark adaptation in patients with complete congenital stationary night blindness and Oguchi disease.

Design

Prospective, observational case series.

Methods

We recruited 3 patients with complete congenital stationary night blindness caused by mutations in GRM6, 2 brothers with Oguchi disease caused by mutations in GRK1, and 1 normal control. Retinal thickness was measured from optical coherence tomography images. Integrity of the rod and cone mosaic was assessed using adaptive optics scanning light ophthalmoscopy. We imaged 5 of the patients after a period of dark adaptation and examined layer …

Patterns In Environmental Drivers Of Wetland Functioning And Species Composition In A Complex Peatland, Jeremy A. Graham

Theses

The boreal peatlands that cover much of western Canada are immense reservoirs of organic carbon and nitrogen, serving as sinks for atmospheric carbon, as well as providing habitat for flora and fauna, and nutrient cycling. These ecosystems are generally believed to be nitrogen limited. Due to regional increases in industrial activities associated in the Athabasca Oil Sands Region (AOSR), atmospheric deposition of nitrogen is projected to increase, with unknown effects on peatland functioning. The results of this study provide baseline data for a nitrogen fertilization experiment with an accurate site description of the entire peatland complex to provide reference for …

Learning Disabilities And Substance Use, Marqueeta L. Harrington

Research Papers

No abstract provided.

Prospect Theory Does Not Describe The Feedback-Related Negativity Value Function., Thomas D. Sambrook, Matthew Roser, Jeremy Goslin

School of Psychology

Humans handle uncertainty poorly. Prospect theory accounts for this with a value function in which possible losses are overweighted compared to possible gains, and the marginal utility of rewards decreases with size. fMRI studies have explored the neural basis of this value function. A separate body of research claims that prediction errors are calculated by midbrain dopamine neurons. We investigated whether the prospect theoretic effects shown in behavioral and fMRI studies were present in midbrain prediction error coding by using the feedback-related negativity, an ERP component believed to reflect midbrain prediction errors. Participants' stated satisfaction with outcomes followed prospect theory …

The Effects Of Growth Hormone On Primary Bovine Mammary Cell Models, Lisa Mcdonnell

Master's Theses

The ability of exogenous growth hormone (GH) to increase milk yield through insulin-like growth factor-1 (IGF-I) in dairy cows is well characterized. However, recent studies utilizing mammary epithelial cell lines indicate a direct effect of GH on mammary epithelial cells (MEC). To test if these observations are relevant in vivo and if this response differs between dairy breeds, three mammary models were utilized. Mammary explants from a lactating Jersey cow were cultured in classical lactogenic media (dexamethasone, insulin, and prolactin) with 0 or 10 ng/mL of recombinant bovine GH for 12h. Primary MEC from lactating Holstein and Jersey cows were …

Low Cost Neurochairs, Frankie Pike

Master's Theses

Electroencephalography (EEG) was formerly confined to clinical and research settings with the necessary hardware costing thousands of dollars. In the last five years a number of companies have produced simple electroencephalograms, priced below $300 and available direct to consumers. These have stirred the imaginations of enthusiasts and brought the prospects of "thought-controlled" devices ever closer to reality. While these new devices were largely targeted at video games and toys, active research on enabling people suffering from debilitating diseases to control wheelchairs was being pursued. A number of neurochairs have come to fruition offering a truly hands-free mobility solution, but whether …

Effect Of Short-Term Estrogen Depletion On Compact Bone Microdensitometry In The Ewe, Cailyn Bugbee

Master's Theses

Osteoporosis affects the human skeleton through the direct effects of the disease on the function and structure of bone. Individuals who are affected by osteoporosis may be subject to serious fractures and it is estimated that annually approximately 1.5 million fractures can be attributed to this disease [1]. The disease is categorized as the direct side effect of increased bone porosity and bone loss and is directly linked to estrogen deprivation [2]. Animal models are often used to make initial conclusions about the effects of the disease or pharmacological treatments. In this study, sheep were chosen as a representative animal …

Effects Of Seawater On The Mechanical Behavior Of Composite Sandwich Panels Under Monotonic Shear Loading, Thomas Robert Woo

Master's Theses

Abstract

Salt water environments are very harsh on materials that are used within them. Many issues are caused by either corrosion and/or internal degradation to the materials themselves. Composites are better suited for this environment due to their high strength to weight ratios and their corrosion resistance, but very little is known about the fracture mechanics of composites. The goal of this study is to gain a better understanding for the behavior of a composite boat hull under a shear loading, similar to the force water applies on the hull as the boat moves through the water; then attempt to …

Bioflocculation Of Wastewater Treatment Pond Suspended Solids, Louis Lefebvre

Master's Theses

Bioflocculation of Wastewater Treatment Pond Suspended Solids

Louis Lefebvre

Wastewater treatment lagoons and high rate algae ponds (HRAPs) can provide cost effective wastewater treatment, but they commonly have high effluent concentrations of total suspended solids (TSS). In this thesis algae pond effluent was treated in a beaker testing apparatus (mixed and aerated) with various mixtures of activated sludge and primary effluent simulating differing activated sludge aeration basin compositions then was allowed to settle to assess settleability. Conventionally, microalgal suspended solids are removed by chemical coagulation followed by separation methods that often have a high cost relative to the low cost …

House Finches, Carpodacus Mexicanus: Hormones, Stress, And Song Control Regions, Katherine Olivia Ganster

Master's Theses

Song production in songbirds is controlled by parts of the brain known as the song control regions (SCRs). During spring, gonads increase in size, males sing to attract mates, and SCRs become larger. This neuroplasticity is controlled by the change in day length and increased plasma testosterone (T) levels. Plasma T can be reduced by stress through the production of corticosterone (CORT), through the production of beta-endorphin, or through direct effects on the testes via the nervous system. We determined the T, estradiol, and CORT hormonal profiles of wild House Finches by capturing and sampling blood from the finches every …

Performance Of A Wastewater Treatment Pond System With Microfiltration, Eric Todd Martin

Master's Theses

ABSTRACT

PERFORMANCE OF A WASTEWATER TREATMENT POND SYSTEM WITH

MICROFILTRATION

Eric Martin

The Woodlands Wastewater Treatment Plant (WWWTP) treats wastewater from the Woodlands housing community near Nipomo, California. The treated effluent is recycled for irrigation of a golf course within the community. The treatment facility consists of three facultative ponds in series followed by a microfiltration system and chlorine disinfection. Microfiltration of wastewater pond effluent is a fairly new, and potentially challenging, application of microfiltration. This thesis describes the operating conditions and behavior of the WWWTP pond system followed by a microfiltration system for the purpose of producing recyclable water …

The Impact Of Outward Remodeling On Vasodilation In Skeletal Muscle Resistance Arteries, Ryan Robert Gallagher

Master's Theses

Peripheral arterial occlusive disease (PAOD) is an ischemic disease characterized by narrowing of the peripheral arteries due to the accumulation of atherosclerotic plaque in the inner lining of the vessels, which disrupts blood flow to downstream tissues. Blood can be redirected into collateral vessels, natural bypasses around arterial occlusions, causing shear-induced outward remodeling of the vessels. The enlarged vessels facilitate transfer of increased blood flow to downstream tissues. The remodeling process, however, may impair vasodilation, which in turn may cause or contribute to intermittent claudication- transient pain brought on by locomotion. To stimulate the growth of collateral arteries, the femoral …

The Effect Of Cone Opsin Mutations On Retinal Structure And The Integrity Of The Photoreceptor Mosaic, Joseph Carroll, Alfredo Dubra, Jessica C. Gardner, Liliana Mizrahi-Meissonnier, Robert F. Cooper, Adam M. Dubis, Rick Nordgren, Mohamed Genead, Thomas B. Connor Jr., Kimberly E. Stepien, Dror Sharon, David M. Hunt, Eyal Banin, Alison J. Hardcastle, Anthony T. Moore, David R. Williams, Gerald Fishman, Jay Neitz, Maureen Neitz, Michel Michaelides

Biomedical Engineering Faculty Research and Publications

Purpose.

To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations.

Methods.

Eleven subjects were recruited, eight of whom have been previously described. Cone and rod density was measured using images of the photoreceptor mosaic obtained from an adaptive optics scanning light ophthalmoscope (AOSLO). Total retinal thickness, inner retinal thickness, and outer nuclear layer plus Henle fiber layer (ONL+HFL) thickness were measured using cross-sectional spectral-domain optical coherence tomography (SD-OCT) images. Molecular genetic analyses were performed to characterize the OPN1LW/OPN1MW gene array.

Results.

While disruptions in retinal lamination and cone mosaic structure were observed …