Digital Commons Network^™

Purification And Analysis Of Folate-Dye Conjugate, Sravya Mothe

All Capstone Projects

Folate receptor has achieved great importance for use in targeted drug delivery and in vitro and in vivo diagnostic assays. Folate receptor (FR) is over expressed on several cancer cell types and activated macrophages, but exists in relatively low abundance on the surface of non-cancerous tissue and non-inflammatory cells. This unique attribute is the hallmark of folate – targeted methodologies allowing the diagnostic agent and/or drug to be ferried to the specific disease sites while preventing “off target” effects in normal tissues. Although several folate-based dyes have been reported, simple and detailed synthetic and purification methods for these conjugates have …

Help Your Kids Have A Heart-Healthy Halloween, Staff

Browse All News

No abstract provided.

Montana Business Quarterly, Fall 2012, University Of Montana--Missoula. Bureau Of Business And Economic Research

Montana Business Quarterly, 1949-2021

This is an academic publication produced by the Bureau of Business and Economic Research (BBER) at the University of Montana’s College of Business. This is volume 50, number 3.

Profile - Fernbank Museum Of Natural History, James Hagy

Rooftops Project

Any natural history or science museum would be proud to haev the diversity of collections and programmatic resources found at Fernbank Museum of Natural History in Atlanta, Georgia. But few if any can law claim, as Fernbank does, to having “grown out of a forest.” Professor James Hagy, Director of The Rooftops Project, talks wiht Aneli Nugteren, Executive Vice President and Chief Operating Officer of Fernbank Museum, about its unique campus, mission, and facilities.

Grand Valley Magazine, Vol. 12, No. 2 Fall 2012, Grand Valley State University

Grand Valley Magazine

Grand Valley Magazine is a quarterly publication about Grand Valley State University produced by University Communications since 2001.

2012 October, Office Of Communications & Marketing, Morehead State University.

Morehead State Press Release Archive, 1961 to the Present

Press releases for October of 2012.

Cytokinesis-Based Constraints On Polarized Cell Growth In Fission Yeast, K. Adam Bohnert, Kathleen L. Gould

Faculty Publications

The rod-shaped fission yeast Schizosaccharomyces pombe, which undergoes cycles of monopolar-to-bipolar tip growth, is an attractive organism for studying cell-cycle regulation of polarity establishment. While previous research has described factors mediating this process from interphase cell tips, we found that division site signaling also impacts the re-establishment of bipolar cell growth in the ensuing cell cycle. Complete loss or targeted disruption of the non-essential cytokinesis protein Fic1 at the division site, but not at interphase cell tips, resulted in many cells failing to grow at new ends created by cell division. This appeared due to faulty disassembly and abnormal persistence …

Reducing The Discount Rate, Ben L. Trachtenberg

Faculty Publications

This article presents two arguments against the “discounting” of future human lives as part of cost benefit analysis, or CBA. Our first argument is that because CBA has thus far ignored evidence of rising health care expenditures, it underestimates the “willingness to pay” for health and safety that future citizens will likely exhibit, thereby undervaluing their lives. Our second argument is that until recently CBA has ignored the trend of improved material conditions in developed countries, and most agencies continue to ignore it entirely. As time advances, residents of rich countries tend to live better and spend more, meaning that …

Louisiana Agriculture Fall, 2012

Louisiana Agriculture

No abstract provided.

Effect Of Prebiotics On Lactobacillus Acidophilus Growth And Resulting Ph Changes In Skim Milk And A Model Peptone System, D. W. Olson, K. J. Aryana

Faculty Publications

The effect of Raftiline® GR, Raftiline® HP-Gel, and Raftilose® P95 prebiotics on growth curves of the probiotic Lactobacillus acidophilus LA-K and resulting pH changes in skim milk and a model system consisting of 0.1% peptone was investigated. Skim milk (100mL) and 0.1% peptone (100mL) each containing either 1% or 3% Raftiline® GR, Raftiline® HP-Gel, or Raftilose® P95 prebiotics were autoclaved, cooled to 37°C, and inoculated with 0.132mL of L. acidophilus LA-K. Both the growth of L. acidophilus and the changes in pH were followed for 16h at 37°C. The growth was determined by measuring the optical density (turbidity) at 600nm. …

Antenatal Care And The Occurrence Of Low Birth Weight Delivery Among Women In Remote Mountainous Region Of Chitral, Pakistan, Z. Ahmed, S. Khoja, Suha S. Tirmizi

Obstetrics and Gynaecology, East Africa

Objective: Low birth weight (LBW) is closely associated with perinatal morbidity and bears an increased risk for subsequent infant morbidity. The study aimed to assess low birth weight delivery factors among women in Chitral, Pakistan.

Methodology: Mixed Methodology was adopted. Structured data collection tool was used to collect information from medical records of 1316 mothers, followed by interviews and focus group discussions to understand the causes and their remedies. The main outcome measure was infants born with low birth weight LBW (<2.5kg).

Result: There was a significant association between the occurrence of low birth weight and maternal education, paternal education, …

The Role Of Dental Hygienists In Conducting Rapid Hiv Testing, Anthony J. Santella, Susan H. Davide, Marilyn Cortell, Winnie Furnari, Janet Tuthill

Publications and Research

Expanding rapid HIV testing in the dental setting may increase the number of individuals who are aware of their HIV status and can begin medical care and social support services if seropositive and appropriate.

Start Your Day Right, Winston J. Craig

Lake Union Herald

No abstract provided.

Farmers Markets And The Local Food System: The Case Of Gettysburg, Pennsylvania, Paul A. Di Salvo, Claire Quinn, Robin Arnold, Caroline Clark, Suzanne Englot, Andrew Mello, Julia P. Mitchell, Emily Ruhl, Rebecca Taormina, Cashin Conover, Valerie Leone, Michael Mattaini, William Patton, Elizabeth Rouillard, Nicholas Smith-Herman, Jordan Swenson, Kelly Webster, Brian Wooldredge, Randall K. Wilson

Student Publications

In order to examine and obtain a better understanding of the local food system within Adams County, Pennsylvania, this study explores the characteristics and perspectives of the customers and vendors at the farmers markets in Gettysburg, Pennsylvania. Survey findings from the Gettysburg Farmers Market and the three Adams County Farmers Markets include customer demographic information, perspectives and shopping behavior as well as vendor product information, farm size and location and preference for market management. Introductory background information on the Farm Bill and the influence of agricultural practices on the environment, human health and nutrition and the relationship between farmers markets …

Oncolog, Volume 57, Number 10, October 2012, Jill Delsigne, Sunni Hosemann

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Treatments May Alleviate and Reverse Central Nervous System Radiation Necrosis: Although radiation therapy is effective against many tumors of the brain and spine, it also damages normal tissue
• INBRIEF: Bevacizumab With High-Dose Chemotherapy Shows Promise for Cisplatin-Refractory Germ Cell Tumors
• Compass: Early-Stage Testicular Cancer-Postsurgical treatment varies according to tumor stage and histology
• HOUSE CALL: Online Cancer Support Networks-Patients and caregivers find support online

The Price They Pay: Protecting The Mother-Child Relationship Through The Use Of Prison Nurseries And Residential Parenting Programs, Anne E. Jbara

Indiana Law Journal

Over the past century, while advocates of prison nurseries have applauded their individual and societal benefits, opponents have criticized their touchy-feely undertones, arguing that children do not belong behind bars. New York instituted the first modern prison nursery program in 1901 at its Bedford Hills facility, and the nursery has existed ever since. The federal government and a number of other states have followed suit in developing programs that, to varying degrees, give mothers and infants an opportunity to remain together until the infant reaches a particular age. The requirements for such programs vary by state but generally only permit …

Two Sides Of The Megalopolis: Educating For Sustainable Citizenship, Alexander Pope, Timothy Patterson

Education Faculty Publications

Despite widespread focus on literacy and math at the expense of other subjects, citizenship and environmental education have an important role in American public education. Citizenship and environmental education are broadly tasked with helping students develop the knowledge, skills, and attitudes needed to shepherd the body politic and natural world, respectively, into the future. For educators and administrators concerned with instructional efficiency, educational farm visits offer one means of pairing these two approaches into a unified learning experience. This paper presents findings from a qualitative case study analysis of two such programs, incorporating interviews with and observations of visiting students, …

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 2012), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 2012 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Message from the President
• PCOM Updates
• Development News
• Protecting Human Rights
• Relieving Suffering
• On Leaders and Legacies
• Profiles of Nine PCOM Alumni Who Influence Osteopathic Medical Education
• Pharmacists’ Changing Role: From Behind the Counter to Direct Patient Care
• PCOM School of Pharmacy Is Preparing Students to Practice as Part of the Healthcare Team
• Class Notes
• In Memoriam
• My Turn Essay
• The Fund for PCOM

Nebline, October 2012

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Feature: Make Every Drop Count in the Home

Farm Views

Urban Agriculture

Food & Fitness

Home & Family Living

Horticulture

Environmental Focus

4-H & Youth

Community Focus

Extension Calendar

Nutrition Education Program

Family and Community Education (FCE) Clubs

and other extension news and events

How Youth Are Put At Risk By Parents’ Low-Wage Jobs, Lisa Dodson, Randy Albelda, Diana Salas Coronado, Marya Mtshali

Center for Social Policy Publications

In this report, we present a first-ever overview of what is known about the relationship between the status of youth and their parents’ low-wage jobs. Of the 20 million adolescents with working parents, 3.6 million (one out of every six) are in low-income families where parents have low-wage jobs. We identify several ways that young people are harmed by their parents’ low-wage, low-quality jobs that point to the urgency of this issue.

Breakfast And Lunch Participation In Massachusetts Schools, Center For Social Policy, University Of Massachusetts Boston, Massachusetts Budget And Policy Center, Massachusetts Law Reform Institute, Eos Foundation

Center for Social Policy Publications

The Center for Social Policy at the University of Massachusetts Boston (CSP), the Massachusetts Budget and Policy Center (MassBudget), and the Massachusetts Law Reform Institute (MLRI), with support from the Eos Foundation, established a research team to examine school food and related programs in Massachusetts.

While the team developed an overview of all federally funded food programs in Massachusetts, the focus of our work was on school meal programs and several aspects of the Supplemental Nutritional Assistance Program (SNAP). The full project is composed of several individual pieces of research and analysis, most of which were primarily undertaken by one …

Variations In Carotenoids In Plasma From Jersey Cows At An Organic Dairy Compared To A Conventional Dairy Over Time, Jillian M. Smith

Honors Theses and Capstones

Interest in organic milk is increasing. By USDA Certified Organic standards, animals must be fed on pasture for a minimum of 120 days. Research indicates that various factors such as diet impact the nutritional quality and composition of milk. The objective of this study was to understand how feeding practices affected bovine plasma carotenoid concentrations over time. Plasma samples were collected from 9 cows fed on pasture at an organic dairy and from 9 cows fed total mixed ration (TMR) at a conventional dairy. Components were extracted from the plasma and separated via High Performance Liquid Chromatography. Results showed that …

Effects Of Incremental Dietary Levels Of Ground Flaxseed On Milk Production, Ruminal Metabolism, And Enteric Methane Emissions In Organic Dairy Cows, Katie Velez

Honors Theses and Capstones

Ground Flaxseed (Linum uitatissimum) is a lipid supplement that is commonly fed to dairy cows. It is believed that supplemental lipid can change the Fatty Acid (FA) composition in the milk, and decrease methane production. Twenty lactating organic Jersey cows, housed at the UNH Organic Dairy Research Farm (ODRF), were randomly assigned to five replicated 4 × 4 Latin squares to investigate the effects of increasing dietary levels of ground flaxseed (0, 5, 10, or 15% of the diet dry matter) on animal fperformance (e.g., dry matter intake, milk production, milk composition), ruminal metabolism, and enteric methane emissions. Each …

Biosecurity Risk Assessment Of The Fairchild Dairy Nutrition Research Center, Margaret Lynch

Honors Theses and Capstones

No abstract provided.

Chemical Proteomics-Based Analysis Of Off-Target Binding Profiles For Rosiglitazone And Pioglitazone: Clues For Assessing Potential For Cardiotoxicity, Brian R. Hoffmann, Mohamed F. El-Mansy, Daniel S. Sem, Andrew S. Greene

Chemistry Faculty Research and Publications

Drugs exert desired and undesired effects based on their binding interactions with protein target(s) and off-target(s), providing evidence for drug efficacy and toxicity. Pioglitazone and rosiglitazone possess a common functional core, glitazone, which is considered a privileged scaffold upon which to build a drug selective for a given target—in this case, PPARγ. Herein, we report a retrospective analysis of two variants of the glitazone scaffold, pioglitazone and rosiglitazone, in an effort to identify off-target binding events in the rat heart to explain recently reported cardiovascular risk associated with these drugs. Our results suggest that glitazone has affinity for dehydrogenases, consistent …

Developing Health Information Literacy: A Needs Analysis From The Perspective Of Preprofessional Health Students, Lana V. Ivanitskaya, Kaitlyn A. Hanisko, Julie A. Garrison, Samantha J. Janson, Danielle Vibbert

Scholarly Papers and Articles

Objective: The research identified the skills, if any, that health preprofessional students wished to develop after receiving feedback on skill gaps as well as any strategies they intended to use to address these gaps.

Methods: A qualitative approach was used to elicit students' reflections on building health information literacy skills. First, the students took the Research Readiness Self-Assessment instrument, which measured their health information literacy, and then they received individually tailored feedback about their scores and skill gaps. Second, students completed a post-assessment survey asking how they intended to close identified gaps in their skills on these. Three trained coders …

Recommended Actions For Improved Care Transitions: Mental Ilnesses And/Or Substance Use Disorders, Chris Walker, Paul Goering, Cathy Brouwer, Kathy Knight, Karen Lloyd, Terry W. Crowson, Michael A. Trangle, Paul Davis, Jennifer Mcnertney, Sue Abderholden, Nancy Houlton, Kathy Cummings, Joann Foreman

Articles

The transition period between care settings is the most vulnerable time for patients and their caregivers. The unique vulnerabilities for patients with mental illnesses such as depression, mania, anxiety, schizophrenia and/or substance use disorders* heighten the need for coordinated transitions and aftercare. In 2010, depression was the fourth diagnosis by volume for readmissions in Minnesota according to the Potentially Preventable Readmissions data collected by the Minnesota Hospital Association.

The Importance Of Host Plant Limitation For Caterpillars Of An Arctiid Moth (Platyprepia Virginalis) Varies Spatially, Richard Karban, Patrick Grof-Tisza, John L. Maron, Marcel Holyoak

Biological Sciences Faculty Publications

Spatial dynamic theories such as source–sink models frequently describe habitat-specific demographies, yet there are surprisingly few field studies that have examined how and why interacting species vary in their dynamics across multiple habitat types. We studied the spatial pattern of interaction between a chewing herbivore and its primary larval host plant in two habitat types. We found that the interaction between an arctiid caterpillar (Platyprepia virginalis) and its host (Lupinus arboreus) differed in wet vs. upland dry habitats, as did yearly population dynamics for the caterpillar. In upland sites, there was a strong positive relationship between …

Novelty Interactions Between Herbivorous Fish And Sargassum: Insight Into Macroalgal Phase Shifts, Christopher Pickens

Independent Study Project (ISP) Collection

Herbivores play a key role in the maintenance of algal and coral communities. A reduction in herbivory has been shown to result in a shift to a macroalgae dominated system, which can have significant effects on the biodiversity and restorative capabilities of coral reefs. Several studies have been done to better understand how herbivorous communities respond to macroalgae. These have shown that only certain herbivorous taxa are capable of removing macroalgae and there are several factors (depth, density, etc.) that affect the susceptibility of macroalgae to herbivory. However, few studies have yet to determine if the novelty of the resource …

Branding Lazos De Amor: Importance And Challenges Of Branding Small Non-Profits, The Journey Towards A Better Brand., Sugey Terrero

Capstone Collection

Branding is an integral journey that precedes, includes and surpasses any marketing and advertising effort; it entails an internal process of self-discovery, combined with the exportation (marketing) of organizational values through visual and tangible means (advertising). This capstone focused on the following questions: why is branding important for non-profits? What factors contribute to non-profits not focusing on branding? In addition, what strategies can small non-profits use to develop and manage their brand more effectively? The first question was explored through literature, while the second was explored both theoretically and empirically beginning with an analysis of why branding is a challenging …