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Medication Expenditure And Resource Utilization Among Patients With Musculoskeletal Disorders: Analysis Of 2007 Medical Expenditure Panel Survey Data, Nipun Atreja

Electronic Theses and Dissertations

Objective: To estimate the national prevalence and direct incremental expenditures of musculoskeletal disorders (MSD's) using the 2007 Medical Expenditure Panel Survey data.

Methods: A retrospective database analysis was conducted and individuals with MSD's (ICD-9-CM codes 274.00; 710.00-738.00) were identified. Dependent variables were total health care and other service category expenditures. The study utilized descriptive and regression analyses.

Results: In 2007, the national prevalence of MSD's was 33 million with incremental costs of $886.49 per person. The inpatient expenditures ($33,461.85) were the highest cost component in MSD's and the predictors of total health care expenditures were age, marital status, and presence …

Chromate Reduction By Desulfovibrio Desulfuricans Atcc 27774, Ning Zhang

Electronic Theses and Dissertations

Chromium has been used extensively in the industry process of metal refinishing and electroplating. It is also a byproduct of the processing of fissionable materials at United States Department of Energy facilities. Chromate (Cr (VI)) is soluble and readily absorbed by cells, while the reduced form of chromium, Cr (III), is insoluble. Thus means of reducing Cr (VI) to Cr (III) in the environment is a potential means of remediation. Desulfovibrio desulfuricans strain 27774 is a sulfate reducing bacterium that can reduce Cr (VI). It also can respire nitrate to ammonia. As some sites of chromium contamination also contain high …

Synthesis Of Furo[2,3-D]Pyrimidines, Thieno[2,3- D]Pyrimidines, Pyrrolo[2,3-D]Pyrimidines As Classical And Nonclassical Antifolates, Receptor Tyrosine Kinase (Rtk) Inhibitors And Antimitotic Agents, Xin Zhang

Electronic Theses and Dissertations

An introduction, background and research progress in the areas of antifolates, receptor tyrosine kinase (RTK) inhbitors and anti mitotic agents has been discussed. Thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFTase) are important folate dependent enzymes that are targets for cancer chemotherapy and the treatment of infectious diseases. Classical antifolates, in most cases, are substrates for folypoly - γ - glutamate synthase (FPGS) and rely on folate transporter systems to enter cells. As a part of this study, twenty - eight compounds were designed on the basis of existing clinically active compounds and crystal structures, synthesized and …

Synthesis Of Bicyclic Thieno[2,3-D]Pyrimidines, Tricyclic Thieno[2,3-D]Pyrimidines And Thieno[3,2-D]Pyrimidines As Classical And Nonclassical Antifolates, Xilin Zhou

Electronic Theses and Dissertations

An introduction, background and research progress in the areas of antifolates and antimitotic agents has been reviewed and discussed. Thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFTase) are important folate dependent enzymes that are targets for cancer chemotherapy and the treatment of infectious diseases. As a part of this study, thirty-five novel compounds were designed and synthesized on the basis of existing clinically active compounds and their crystal structures. These compounds were synthesized and evaluated as single and/or muliple targeted classical and nonclassical antifolates to decrease toxicity and improve the antitumor activity and selectivity of existing therapeutic …

Molecular Mechanisms Regulating Chronological Aging And Cell Death In The Toxic Dinoflagellate, Karenia Brevis, Jillian Grace Johnson

MUSC Theses and Dissertations

The toxic dinoflagellate, Karenia brevis, forms nearly annual blooms in the Gulf of Mexico that persist for many months in coastal waters, causing extensive marine animal mortalities and human health impacts. The molecular mechanisms that contribute to cell survival in high density, low growth blooms, and the mechanisms leading to often rapid bloom demise are not well understood. The studies presented in this dissertation investigate the existence and involvement of a programmed cell death-like (PCD-like) pathway in the demise of K. brevis cultures following oxidative stress and chronological aging. Firstly, to gain an understanding of the molecular processes that underlie …

Computational Methods For The Differential Profiling Of Triacylglycerols Using Rp-Hplc/Apci-Ms, Margaret Holbrook Broadwater

MUSC Theses and Dissertations

Reversed phase liquid chromatography with atmospheric pressure chemical ionization mass spectrometry (RP-HPLC/APCI-MS) was employed for the analysis of natural mixtures of triacylglycerols. An integrated framework for data analysis, including preprocessing, statistical analysis and automated structure identification, was implemented in the R statistical program. Raw data stored as mzXML, mzData, or mzXML files are preprocessed using a series of steps for peak detection, chromatographic alignment, and normalization. Targeted and non-targeted feature selection steps are employed to filter the data for features that are relevant and informative for a particular biological question. Triacylglycerol structures are identified by evaluating relationships between the diacylglycerol …

Rehabilitation Utilization And The Marginal Cost Of Ischemic Stroke In South Carolina, Ann-Catherin Simpson

MUSC Theses and Dissertations

This study uses Medicare claims from 1997 and 2004 to examine two important health policy issues using patients with ischemic stroke as an example. We explore the differences in rehabilitation services utilization and expenditures for stroke prior to and after outpatient rehabilitation caps were enacted. We then examine the effect of using a total cost approach versus a marginal cost method to estimate the first year cost of stroke and stroke rehabilitation. We found the cap did constrain outpatient rehabilitation utilization and cost of rehabilitation services if examined only using Medicare Part B provider costs, but not when facility costs …

The Epigenetic Regulation Of Cubilin And The Physiological Role Of This Receptor In Maintaining The Homeostasis Of Serum Albumin And Hdl, Sayed Obaidullah Aseem

MUSC Theses and Dissertations

Cubilin is an endocytic receptor capable of mediating the endocytosis of multiple ligands including High Density Lipoprotein apolipoprotein A-I (apoA-1) and albumin. It is highly expressed on the epithelium of intestinal villi and renal proximal tubules. In the kidney, endocytosis mediated by cubilin and its co-receptor megalin is the principal mechanism for proximal tubule reabsorption of filtered proteins, such as albumin and apoA-1. Yet, the consequences of cubilin deficiency on the blood levels of albumin and apoA-1 have not been studied. Furthermore, cubilin is downregulated in chronic diseases such as diabetes. However, little is known about the regulation of cubilin …

2012 Transactions, American Dental Association

ADA Transactions

This item is part of the Transactions of the ADA, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT). It is from the Transactions section, one of three subtitles that make up the full publication. Generally, the ADA Transactions are published in multiple volumes throughout the year. Pages from the Annual Reports and the Transactions are numbered consecutively (e.g. Annual Reports volume ends pg. 500 and Transactions volume starts at pg. 501). NOTE: All three subtitles are collectively known as the Transactions of the ADA or, alternatively, the ADA Transactions. Transactions refers …

Keratin 8/18 Filaments: Potential Modulators Of Death Signaling In Ovarian Granulosa Cells, Sarah E. Kinsman

Master's Theses and Capstones

Granulosa cell apoptosis is associated with follicular atresia; but the cellular mechanisms that drive this process, especially its cell specificity, are relatively unknown. Here, we determined that cultured granulosa cells abundantly express K8/K18 filaments and inhibition of protein synthesis enhances Fas-induced apoptosis. In this context, the roles of cFLIP, ERK1/2 and Akt are minimal but conversely, K8/K18 filaments have a prominent role in granulosa cell resistance to Fas-induced apoptosis. Keratin 8/18 filaments in granulosa cells provide a plausible mechanism to avoid Fas-induced apoptosis and this mechanism potentially involves the synthesis of labile proteins. The existence of K8/K18 filaments in granulosa …

Impact Of Family Meal Time On College Students' Food Consumption And Select Lifestyle Choices, Rachael Jannusch

Undergraduate Honors Theses

People participating in family mealtimes ≥ 6 times per week while growing up are known to have a better quality diet, GPA, sleeping habits, and a normal BMI. It is hypothesized that college students with a history of family mealtimes continue to experience these benefits while in college. The purpose of this study is to investigate the impact of the history of family mealtime on diet quality, GPA, sleeping habits, and BMI in a college setting.

A convenience sample of students at a midwestern university (n=100) were asked to complete a 17 question survey regarding frequency of family meals, food …

Survival Analysis Of Dialysis Patients Under Parametric And Non-Parametric Approaches, Maryam Siddiqa, Mueen -Ud -Din Azad, Muhammad K. Pervaiz, Muhammad Ghias, Gulzar H. Shah, Uzma Hafeez

Health Policy & Management: Faculty Publications (2006-2018)

Dialysis is a recommended way of treatment for end stage kidney diseases and it provides a life saving procedure. Transplantation can also be useful source but it is restricted by financial limitations especially in developing countries like Pakistan. Censoring is an important part of the survival data which causes insensitivity to the usual procedures of analysis. A little work has been done in literature regarding the estimated survival time of dialysis patients in Pakistan. So, this study has estimated the median survival time of male/females patients separately by parametric and non-parametric approaches. Moreover, comparison of survival time to patients (50 …

Music Therapy Within The Context Of Psychotherapeutic Models, Mary Scovel, Susan Gardstrom

Department of Music Faculty Publications

Music therapy clinical practice occurs at various levels. Wheeler (1983) has classified the treatment of adults with mental disorders into three types: music therapy as an activity therapy; insight music therapy with re-educative goals; and insight music therapy with reconstructive goals.

Activity-based therapy is aimed at helping the client reach observable, measurable goals through various forms of music experiences. In contrast, the two remaining levels focus on facilitation of change through personal insight gained via musical experiences and verbalization about those experiences. Insight-based music therapy processes are ordinarily more intense and prolonged, in that deep emotions are evoked, and in …

The Effect Of Pre-­Meal, Vocal Re-Creative Music Therapy On Nutritional Intake Of Residents With Alzheimer’S Disease And Related Dementias: A Pilot Study, Larisa Mchugh, Susan Gardstrom, James Hiller, Megan Brewer, Wiebke S. Diestelkamp

Department of Music Faculty Publications

Singing has long been credited with a wide variety of physical, mental, and social health benefits (Hunter, 1999). Recent scientific inquiry points to the efficacy of singing toward enhanced cardiovascular and pulmonary performance (Bonilha, Onofre, Vieira, Prado, & Martinex, 2009), verbal communication (Wan, Ruber, Hohmann, & Schlaug, 2010), and immune functioning and attendant affective states (Kreutz, Bongard, Rohrmann, Hodapp, & Grebe, 2004; Kuhn, 2002; Unwin, Kenny, & Davis, 2002).

Among older adults, singing has been linked with improved mood, better quality of life, greater happiness, stress reduction, and emotional well-being (Clift et al., 2010).

In our own work, we have …

Sickle Cell Anemia, Derek Hayse

A with Honors Projects

What Sickle Cell Anemia is, its symptoms, how it is acquired, how it can be prevented, and how to deal with having it.

Stress Reduction Process, Noor Judeh

A with Honors Projects

This paper identifies the background and causes of stress and the different techniques that can be used to reduce stress.

Management By Menu, Mark Lavern Badeaux

A with Honors Projects

This project includes a PowerPoint presentation and excel worksheet explaining the procedures in how to manage and succeed in a food service operation.

Synapsis: Georgia Campus (2012), Philadelphia College Of Osteopathic Medicine

All Yearbooks

Includes Corley Elementary Health Fair, Student Government Association, Class Officers, Clubs, Emergency Medicine, Internal Medicine, Ob/Gyn, Obstetrics/Gynecology, Ophthalmology, Play, Complimentary and Atlernative Medicine, Student National Medical Association, SNMA, Christian Medical and Dental Association, Undergraduate American Association of Osteopathy, UAAO, Surgery, Association of Military Osteopathic Physicians & Surgeons, AMOPS, SIGN, Student Osteopathic Medical Association, SOMA, Sigma Sigma Phi, SSPh, (ΣΣΦ), Sports Medicine, Halloween Formal, Belize Mission Trip 2009, DO Day on the Hill, White Coat Ceremony, Green Team, White Water Rafting, Adopt-a-Highway, OMT Fellows

Developmental Expression Of Drop-Dead Is Required For Early Adult Survival And Normal Body Mass In Drosophila Melanogaster, Christine Lynn Sansone, Edward M. Blumenthal

Biological Sciences Faculty Research and Publications

In Drosophila melanogaster, mutations in the gene drop-dead (drd) result in early adult lethality, with flies dying within 2 weeks of eclosion. Additional phenotypes include neurodegeneration, tracheal defects, starvation, reduced body mass, and female sterility. The cause of early lethality and the function of the drd protein remain unknown. In the current study, the temporal profiles of drd expression required for adult survival and body mass regulation were investigated. Knockdown of drd expression by UAS-RNAi transgenes and rescue of drd expression on a drd mutant background by a UAS-drd transgene were controlled with the Heat Shock Protein …

Results From An Assesment Survey For School Food Service Directors And School Foodservice Managers Participating In The 2011-2012 South Carolina Farm To School Program, Maciel Ugalde

All Theses

In South Carolina (SC), children aged 10-17 are ranked 13th in the United States for overweight and obesity (33.7%) according to the National Survey of Children's Health 2007. Fruit and vegetable intake in children and adolescents in the United States is below recommended levels (Lorson, Melgar-Quinonez, & Taylor, 2009). In SC, only 15% of the high school students consume fruits and vegetables five or more times per day. Fruit and vegetable consumption has been associated with reduced risk of chronic diseases (Epstein et al., 2001; Knai, Pomerleau, Lock, & McKee, 2006; Reichmann, 2009). Schools are identified as a key setting …

Effects Of Walnut Consumption On Cognitive Performance In Young Adults, Peter Pribis, Rudolph N. Bailey, Andrew A. Russell, Marcia A. Kilsby, Magaly Hernandez, Winston J. Craig, Tevni Grajales, David J. Shavlik, Joan Sabatè

Faculty Publications

Walnuts contain a number of potentially neuroprotective compounds like vitamin E, folate, melatonin, several antioxidative polyphenols and significant amounts of n-3 α-linolenic fatty acid. The present study sought to determine the effect of walnuts on verbal and non-verbal reasoning, memory and mood. A total of sixty-four college students were randomly assigned to two treatment sequences in a crossover fashion: walnuts-placebo or placebo-walnuts. Baseline data were collected for non-verbal reasoning, verbal reasoning, memory and mood states. Data were collected again after 8 weeks of intervention. After 6 weeks of washout, the intervention groups followed the diets in reverse order. Data were …

Effects Of Root-Zone Temperature And N, P, And K Supplies On Nutrient Uptake Of Cucumber (Cucumis Sativus L.) Seedlings In Hydroponics, Qiuyan Yan, Zengqiang Duan, Jingdong Mao, Xun Li, Fei Dong

Chemistry & Biochemistry Faculty Publications

The nutrient uptake and allocation of cucumber (Cucumis sativus L.) seedlings at different root-zone temperatures (RZT) and different concentrations of nitrogen (N), phosphorus (P), and potassium (K) nutrients were examined. Plants were grown in a nutrient solution for 30 d at two root-zone temperatures (a diurnally fluctuating ambient 10°C-RZT and a constant 20° C-RZT) with the aerial parts of the plants maintained at ambient temperature (10°C -30°C). Based on a Hoagland nutrient solution, seven N, P, and K nutrient concentrations were supplied to the plants at each RZT. Results showed that total plant and shoot dry weights under …

Child Welfare Cases Involving Mental Illness: Reflections On The Role And Responsibilities Of The Lawyer-Guardian Ad Litem, Frank E. Vandervort

Articles

Child welfare cases involving mental illness suffered either by a child or his parent can be among the most difficult and perplexing that a child’s lawyerguardian ad litem (L-GAL) will handle. They may present daunting problems of accessing necessary and appropriate services as well as questions about whether and when such mental health problems can be resolved or how best to manage them. They also require the L-GAL to carefully consider crucially important questions—rarely with all the information one would like to have and too often with information that comes late in the case, is fragmented or glaringly incomplete. This …

Shaken Baby Syndrome, Abusive Head Trauma, And Actual Innocence: Getting It Right, Keith A. Findley, Patrick D. Barnes, David A. Moran, Waney Squier

Articles

In the past decade, the existence of shaken baby syndrome (SBS) has been called into serious question by biomechanical studies, the medical and legal literature, and the media. As a result of these questions, SBS has been renamed abusive head trauma (AHT). This is, however, primarily a terminological shift: like SBS, AHT refers to the two-part hypothesis that one can reliably diagnose shaking or abuse from three internal findings (subdural hemorrhage, retinal hemorrhage, and encephalopathy) and that one can identify the perpetrator based on the onset of symptoms. Over the past decade, we have learned that this hypothesis fits poorly …

Hispanic Health Care In West Michigan, Megan Stanitzek

Honors Projects

No abstract provided.

The Association Between Levels Of Physical Activity And Body Mass Index With Under-Reporting Of Energy In Middle-Class African American Women: Data Analysis And Results, Hannah Hollandsworth

Honors Projects

No abstract provided.

Applying Holder In An Irregular War, Ellen Porter

Public Interest Law Reporter

No abstract provided.

Student-Teachers' Metaphorical Perceptions Of Dyslexia And Foreign Language Disabilities, Tsafi Timor

Electronic Journal for Inclusive Education

There seems to be an ongoing controversy among researchers with regard to the existence of LD in foreign language (FLLD). It appears that most researchers favor the analogy of FLLD to obesity rather than to measles as both LD and obesity are conditions which reside on a continuum. The study examined EFL student-teachers' perceptions of FL learning problems with regard to the analogy to obesity and to measles from previous studies. The methodology was content analysis of an online forum as part of an academic course. Findings show that most student-teachers perceive FL learning problems as obesity because they find …

Rights Of Ohio Mothers: Best Practices For The Pediatric Patient With A Life-Threatening Illness, Kelly Peekstok

Master of Public Health Program Student Publications

The purpose of this paper is to evaluate and review current best practices with regards to a minor’s refusal of life-sustaining medical treatment. The policies of other developed countries and states within the United States serve as a guide for developing evidence-based guidelines for Ohio healthcare professionals. Four specific cases were identified and then analyzed. The results showed that in three of the four cases, the wishes of the minor were followed. While each case contains its own set of complexities, creating a developmental guideline for healthcare organizations will ensure protection of the minor’s capacity to make autonomous decisions.

Chronic Disease Prevalence Of A Refugee Population In Dayton, Oh, Sandeep Palakodeti

Master of Public Health Program Student Publications

Introduction: This study aimed to understand the chronic disease burden of anemia, cancer, diabetes mellitus, hypertension, overweight/obesity, stroke, and tobacco use in the domestic as well as a refugee population. It also aimed to examine the current literature on appropriate screening for those conditions.

Methods: 348 refugee screening intake exams from Public Health - Dayton & Montgomery County were analyzed for presence of the conditions stated. Screening intake recommendations from the CDC, the Minnesota Public Health Department, the Canadian Collaboration for Immigrant and Refugee Health, and the Ohio Department of Job and Family Services were examined and compared in order …