Digital Commons Network^™

Genetic Modulation Of Lipid Profiles Following Lifestyle Modification Or Metformin Treatment: The Diabetes Prevention Program, Toni I. Pollin, Tamara Isakova, Kathleen A. Jablonski, Paul I.W. De Bakker, Andrew Taylor, Jarred B. Mcateer, Qing Pan, Edward Horton, Linda M. Delahanty, David Altshuler, Alan R. Shuldiner, Ronald Goldberg, Jose C. Florez, George A. Bray

Epidemiology Faculty Publications

Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a genetic risk score (GRS) based on deleterious alleles at 32 lipid-associated single-nucleotide polymorphisms modifies the effects of lifestyle and/or metformin interventions on lipid levels and nuclear magnetic resonance (NMR) lipoprotein subfraction size and number. Twenty-three loci previously associated with fasting LDL-C, HDL-C, or triglycerides replicated (P = 0.04–1×10−17). Except for total HDL particles (r = −0.03, …

August 30, 2012, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Stubborn, Persistent, Dangerous C.Difficile Infections. Is Improvement Possible?, Sara Townsend

Master of Science in Healthcare Quality and Safety Capstone Presentations

C.difficile also known as C.diff or CDI has developed into a dangerous infection for the United States’ health care system. While much work has been done to improve C.diff rates, health care teams have not been successful in reducing C.difficile infections. Many studies have focused on the mode of transmission of C.difficle, yet there still is not consensus on understanding how this infection is spread. Bryn Mawr Hospital, a community hospital in the suburbs of Philadelphia, Pa, has struggled to improve their C.diff rates like their peers throughout the country. While their infection rates for C.diff are …

Senior Exercise Science Major Selected For Healthy People Penn State Expo, Winthrop University

Winthrop News 2012

• Shantelle Igiozee was invited to participate in two days of activities Oct. 18-19 with the university’s Healthy People Penn State Research Conference and Expo.
• The program is sponsored by its College of Health and Human Development and School of Nursing to encourage juniors/seniors from traditionally underrepresented groups with solid records of academic achievement to pursue graduate school.

Seasonality & The Local Food System: The Role Of Seasons In Local Food Education In New York City, Sarah Benoit

Urban Studies Masters Theses

Much of the current research on global and local food insecurity – particularly among poor urban populations – strongly suggests that the impacts of industrial agriculture and the American fast food culture has been detrimental to both urban and rural populations, and to small farmers. Food insecurity and unequal access to healthy and affordable food are critical issues in the metropolis. In response to these concerns, there has been a great deal of mobilization around the concept of local and regional food systems. Food systems analysis examines the viability, equitability, and sustainability of the life cycle of the local food …

Committee For 125 - East Tennessee State University Presentation, Committee For 125, East Tennessee State University

ETSU 125 - Chapter I: Introduction and Visioning Process

No abstract provided.

The Daily Egyptian, August 29, 2012, Daily Egyptian Staff

August 2012

No abstract provided.

Efektivitas Nira Aren Sebagai Bahan Pengembang Adonan Roti, Mody Lempang, Albert D. Mangopang

Jurnal Penelitian Kehutanan Wallacea

Fermentation is a natural process that happen in fresh-sweet sap of aren trees (Arenga pinnata Merr.), because many kinds of microorganism stay and life in this substance e.g. bakteria (Acetobacter acetic) and yeast (Saccharomyces tuac). Species of yeast from genus of Saccharomyses, e.g. Saccharomyses serivisae is wellknown as microorganism that can ferment sugar (glucose) into alchohol and CO₂. This natural process as well happen in aren sap, so that this substance potencially using as a swollen agent of bread or cake dough. This research objective is to recognize the effectiveness of aren sap as a swollen agent of …

Volume 50, Number 2: August 29, 2012, University Of North Dakota

University Letter Archive

No abstract provided.

The Bg News August 29, 2012, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. August 29, 2012. Volume 103-Issue 6.

Determining Notoriety In Supreme Court Decisions , G. Edward White

Pepperdine Law Review

No abstract provided.

Atypical Development Of The Cerebellum : Impact On Language Function, Lynette M. Silva

Psychology ETDs

Children born very low birth weight (VLBW; <1800 grams) and/or preterm (<33 weeks gestation) frequently have cerebellar hypoplasia, and a constellation of cognitive deficits. The cerebellum, now shown to be involved in many non-motor functions, has a protracted maturation process similar to the frontal lobes, and new evidence suggests the cerebellum may be more vulnerable to environmental factors than subject to genetics. However, relationships between specific cerebellar structures and cognitive functions have not been extensively investigated. We examined relationships between the volume of four cerebellar regions of interest (ROI) and language performance in two age samples: 27 participants between 16 and 20 months of age and 20 participants between 3 and 4 years old. Language performance was significantly different between VLBW and control groups in both age samples. No significant relationships were evident between language performance and ROI volume in the 18-month-old sample. Anterior vermis volume was significantly correlated with VIQ scores in only the 3-year-old VLBW group, in the absence of a significant group difference in anterior vermis volume. This correlation remained significant in the VLBW group, even when controlling for number of days on ventilation. In terms of predicting group membership, VIQ was the most significant predictor in the 3-year-old sample, with increased specificity when adding right dentate nucleus volume. In terms of predicting VIQ scores, ethnicity was the most significant predictor for the control group, but days of ventilation along with anterior vermis volume best predicted VIQ in the VLBW group. The possibility of a differential relationship between anterior vermis volume and language ability in VLBW children, possibly emerging between 18 months and 3 years of age, may have implications for development of interventions, particularly given environmental vulnerability and the protracted cerebellar maturation process.

Smith Named New Scholar In Aging By The Ellison Medical Foundation, Alicia Rohan

Browse All News

No abstract provided.

Florida Sentinel Bulletin, August 28, 2012, Gwen Hayes

Florida Sentinel Bulletin Collection

The August 28, 2012, issue of the Florida Sentinel Bulletin.

Methods For Cell Therapy, Pablo Caviedes, Raul Caviedes, Thomas B. Freeman, Juan A. Asenjo, Barbara A. Andrews, Dario Sepúlveda, Christian Arriagada, Julio Salazar Rivera

USF Patents

The subject invention pertains to materials and methods for inhibiting process formation and extension by cells in culture. The subject invention further includes cultures of process-forming cells wherein formation and extension of processes have been inhibited. In another aspect, the subject invention concerns methods of transplantation using process-forming cells that have been cultured by the process-inhibiting methods of the invention.

Carrs Surveillance Study: Design And Methods To Assess Burdens From Multiple Perspectives, Manisha Nair, Mohammed K. Ali, Vamadevan S. Ajay, Roopa Shivashankar, Viswanathan Mohan, Rajendra Pradeepa, Hassan Mehmood Khan, Muhammad Masood Kadir, Zafar Fatmi, K Srinath Reddy, Nikhil Tandon, Km Venkat Narayan, Dorairaj Prabhakaran

Community Health Sciences

Background: Cardio-metabolic diseases (CMDs) are a growing public health problem, but data on incidence, trends, and costs in developing countries is scarce. Comprehensive and standardised surveillance for non-communicable diseases was recommended at the United Nations High-level meeting in 2011.
Aims: To develop a model surveillance system for CMDs and risk factors that could be adopted for continued assessment of burdens from multiple perspectives in South-Asian countries.
Design: Hybrid model with two cross-sectional serial surveys three years apart to monitor trend, with a three-year prospective follow-up of the first cohort.Sites: Three urban settings (Chennai and New Delhi in India; Karachi in …

Assessing The Utilization Of Inhaled Corticosteroids And Health Care Services For Asthma By Hispanic And Non-Hispanic White Patients Using The Medical Expenditure Panel Survey, Akshay Kharat

Pharmaceutical Sciences ETDs

Objectives: Inhaled corticosteroids (ICS) are widely used in the management of asthma. Prior research suggests that asthmatic patients access to ICS may vary by ethnicity. The objectives of the study were to determine if there is a difference in the proportion of Hispanic and non-Hispanic White patients in the receipt of ICS prescription for asthma and to determine the independent predictors of receiving an ICS prescription in asthmatic patients. The study further examined the utilization of asthma-related healthcare services (office visits, prescription fills, inpatient visits, and emergency room visits) in Hispanic and non-Hispanic White asthmatic patients. Methods: The U.S. Medical …

Body Composition, Dietary Composition, And Components Of Metabolic Syndrome In Overweight And Obese Adults After A 12-Week Trial On Dietary Treatments Focused On Portion Control, Energy Density, Or Glycemic Index, Kathleen J. Melanson, Amber Summers, Von Nguyen, Jen Brosnahan, Joshua Lowndes, Theodore J. Angelopoulos, James M. Rippe

Nutrition Faculty Publications

Background:

Given the rise in obesity and associated chronic diseases, it is critical to determine optimal weight management approaches that will also improve dietary composition and chronic disease risk factors. Few studies have examined all these weight, diet, and disease risk variables in subjects participating in recommended multi-disciplinary weight loss programs using different dietary strategies.

Methods:

This study compared effects of three dietary approaches to weight loss on body composition, dietary composition and risk factors for metabolic syndrome (MetS). In a 12-week trial, sedentary but otherwise healthy overweight and obese adults (19 M & 138 F; 38.7 ± 6.7 …

Current, August 27, 2012, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

Household Food Security In Developing Countries: Understanding The Role Of Dynamic Natural And Social Systems, Steven Archambault

Economics ETDs

The lack of consistent and reliable levels of nutritious food may be one of the most brutal results of poverty. Beyond the human suffering, the lack of food security has damaging economic consequences, making it difficult for communities to break poverty cycles. This dissertation studies the various decisions made by households, governments, and the international community that impact household food security. Food security, the long-term availability of nutritious foods, is essentially achieved through a trade-off of consumption and investment in assets and capital to ensure future availability of food. Chapter 2 builds an optimal control model to analyze the trade-offs …

Peckham V. Idaho State Bd. Of Dentistry Respondent's Brief Dckt. 39758

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Development Of Species Level Dna Barcodes To Identify Cultivated Edible Mushrooms, F.A. Avin, S. Vikineswary, T.Y. Shin, S. Bhassu

Research Publications (2011 to 2015)

The majority of edible mushrooms belong to Basidiomycetes and these mushrooms have become more important in recent times for their medicinal and nutritional properties. For many years, species of this phylum have been mainly classified by their phenotypic traits, however, taxonomic identification based solely on morphological features can be misleading and unreliable. In contrast, DNA based identification provides a powerful and reliable method for taxonomic discrimination of fungi, it can be performed at any growth stages using parts of the fruit body, mono- and dikaryotic mycelia, or any other organic fungal. In the current study, two different molecular markers including …

Physiological Responses Of Jatropha To Drought Stress In Coastal Sandy Land Conditions, I Gusti Made Arya Parwata, Didik Indradewa, Prapto Yudono, Rukmini Kusmarwiyah

Makara Journal of Science

Jatropha curcas L., an important tropical biofuel crop, is reputed for its drought resistance, however, its ability to perform in dry conditions has still hardly been investigated. Changes in leaf water status, chlorophyll content, leaf surface temperature, stomatal conductance, proline and abcisic acid (ABA) content, transpiration and photosynthetic rate were studied in four Jatropha genotypes (IP-1A, IP-2M, Local superior and Yellow leaf) and subjected to drought stress in coastal sandy land conditions in Central Java, Indonesia. Drought stress significantly decreased the leaf water status, leaf chlorophyll content, stomatal conductance, transpiration and photosynthetic rate, and increased leaf temperature, proline and ABA …

Effect Of Food Security And Federal Food Assistance Participation On Household Availability And Recorded Preschool Child Consumption Of Sugar Sweetened Beverages And 100% Fruit Juice, Katherine A. Yarbrough

Master's Theses

Sugar sweetened beverage consumption is on the rise in the United States, particularly among children. However, the impact of household food security and federal food assistance participation on beverage habits has not been extensively analyzed. This paper sought to fill the current gap in literature on household beverage availability and recorded preschool child consumption of sugar sweetened beverages (SSB) and 100% fruit juice based on food security levels and status of federal food assistance participation. For this thesis, SSB are beverages that have added sugar and include fruit drinks, sodas, sports drinks, syrups, flavored milks, and teas. Baseline data from …

Trace Element Soil Contamination At Urban Community Gardens In Washington, Dc, Adam J. Long

Environmental Analysis Program Mellon Student Summer Research Reports

In recent years, urban gardening has become a popular form of environmental, food, and social justice. Urban community gardens such as those in Washington, DC can reduce the environmental footprint of food production, provide access to healthy produce in “food deserts,” and provide other social, educational, and even financial benefits. However, the rising popularity of urban gardening has put many people in close contact with urban soils, which are likely to contain various contaminants due to concentrated human activity over extended periods of time. This study investigates heavy metal soil contaminants found in community gardens located in Washington, DC. 45 …

The Daily Gamecock, Friday, August 24, 2012, University Of South Carolina, Office Of Student Media

August

No abstract provided.

Sex Determination In Beetles: Production Of All Male Progeny By Parental Rnai Knockdown Of Transformer, Jayendra Nath Shukla, Subba Reddy Palli

Entomology Faculty Publications

Sex in insects is determined by a cascade of regulators ultimately controlling sex-specific splicing of a transcription factor, Doublesex (Dsx). We recently identified homolog of dsx in the red flour beetle, Tribolium castaneum (Tcdsx). Here, we report on the identification and characterization of a regulator of Tcdsx splicing in T. castaneum. Two male-specific and one female-specific isoforms of T. castaneum transformer (Tctra) were identified. RNA interference-aided knockdown of Tctra in pupa or adults caused a change in sex from females to males by diverting the splicing of Tcdsx pre-mRNA to male-specific isoform. All the pupa and adults developed from Tctra …

The New Hampshire, Vol. 102 [103], No. 1 (Aug. 24, 2012), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 102, but it is the 103rd volume in the series. This was corrected in pencil.

Tryptophan Hydroxylase-1 Regulates Immune Tolerance And Inflammation, Elizabeth C. Nowak, Victor C. De Vries, Anna Wasiuk, Cory Ahonen, Kathryn A. Bennett, Isabelle Le Mercier, Dae-Gon Ha, Randolph J. Noelle

Dartmouth Scholarship

Nutrient deprivation based on the loss of essential amino acids by catabolic enzymes in the microenvironment is a critical means to control in ammatory responses and immune tolerance. Here we report the novel nding that Tph-1 (tryptophan hydroxylase-1), a synthase which catalyses the conversion of tryptophan to serotonin and exhausts tryptophan, is a potent regulator of immunity. In models of skin allograft tolerance, tumor growth, and experimental autoimmune encephalomyelitis, Tph-1 de ciency breaks allograft tolerance, induces tumor remission, and intensi es neuroin ammation, respectively. All of these effects of Tph-1 de ciency are independent of its downstream product serotonin. Because …

Chronic Ketamine Administration Modulates Midbrain Dopamine System In Mice, Sijie Tan, Wai Ping Lam, Maria S. M. Wai, Wan-Hua Amy Yu, David T. Yew

Publications and Research

Ketamine is an anesthetic and a popular abusive drug. As an anesthetic, effects of ketamine on glutamate and GABA transmission have been well documented but little is known about its long-term effects on the dopamine system. In the present study, the effects of ketamine on dopamine were studied in vitro and in vivo. In pheochromocytoma (PC 12) cells and NGF differentiated-PC 12 cells, ketamine decreased the cell viability while increasing dopamine (DA) concentrations in a dose-related manner. However, ketamine did not affect the expression of genes involved in DA synthesis. In the long-term (3 months) ketamine treated mice, significant increases …