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2012

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The Effect Of Visualized Student's Self-Set Learning Progress Goals On East Asian Chinese Student's Motivation And Self Confidence In Learning, Yu Ao Jan 2012

The Effect Of Visualized Student's Self-Set Learning Progress Goals On East Asian Chinese Student's Motivation And Self Confidence In Learning, Yu Ao

Electronic Theses and Dissertations

This study was conducted to determine if visualized goal achievement can help enhance East Asian Chinese students‟ motivation in learning and elevate their confidence in reaching their goals thus improving their performance. The goal achievement was visualized on a goal achievement progress chart that was self-created and self-managed by the East Asian Chinese students and the goal creating was under the supervision of their instructor. In this study, literature reviews on the theories, previous research studies in the perspectives of East Asian students‟ motivation in learning, goal setting on motivation, self-determination, self-efficacy, and expectancy theories are conducted to provide theoretical …


Development And Evaluation Of An Instrument To Measure Mother-Infant Togetherness After Childbirth, Carol Lawrence Jan 2012

Development And Evaluation Of An Instrument To Measure Mother-Infant Togetherness After Childbirth, Carol Lawrence

Electronic Theses and Dissertations

No existing measure to date captures mother-infant togetherness. A valid measure of togetherness is essential to engage in evidence-based practice, evaluate obstetric delivery models and nursing interventions, and measure the level of togetherness which promotes optimal maternal-infant outcomes. When together and in close proximity, a women and her infant have access to one another to allow for mutual caregiving or caregiving on cue. A new measure entitled the Mother-Infant Togetherness Scale (MITS) was developed based on a review of the literature and conceptual framework of Mother-Newborn Mutual Caregiving. The MITS is a 35- item instrument composed of four subscales that …


A New Semantic Similarity Join Method Using Diffusion Maps And Long String Table Attributes, Bilal Hani Hawashin Jan 2012

A New Semantic Similarity Join Method Using Diffusion Maps And Long String Table Attributes, Bilal Hani Hawashin

Wayne State University Dissertations

With the rapid increase of the distributed data sources, and in order to make information integration, there is a need to combine the information that refers to the same entity from different sources. However, there are no global conventions that control the format of the data, and it is impractical to impose such global conventions. Also, there could be some spelling errors in the data as it is entered manually in most of the cases. For such reasons, the need to find and join similar records instead of exact records is important in order to integrate the data. Most of …


The Impact Of Spirituality On The Self-Reported Recovery Of Adults Who Experienced Childhood Trauma, Chijioke Alphonsus Chigbo Jan 2012

The Impact Of Spirituality On The Self-Reported Recovery Of Adults Who Experienced Childhood Trauma, Chijioke Alphonsus Chigbo

Wayne State University Dissertations

Objective: To examine whether adults who had experienced childhood trauma, and who had a higher sense of personal meaning or spirituality, would have improved mental health and lower trauma symptoms such as depression, lower self-esteem, anxiety, dissociative disabilities, PTSD, and the like.

Method: 115 participants were randomly selected from five mental health centers in the southeast of the State of Michigan of the United States. Each participant had an experience of one or multiple childhood abuses, namely: physical abuse, sexual abuse, verbal/emotional abuse, child neglect or cumulative trauma. They had also been to treatment, and were between 18 and 60 …


An Examination Of The Impact Of Early Retirement Incentives On School District Financial Health, Michael Jon Dean Jan 2012

An Examination Of The Impact Of Early Retirement Incentives On School District Financial Health, Michael Jon Dean

Wayne State University Dissertations

The combination of state controlled school funding in Michigan, rising employee costs and shrinking school enrollments have caused school districts to seek a variety of cost control measures. One of the measures frequently supported by both school districts and employee unions is the use of Early Retirement Incentives (ERI) to incentivize teachers to separate from the school district via a cash payment.

The purpose of this study was to analyze how offering or not-offering an ERI impacted on the financial health of a school districts in the State of Michigan. Selected school districts in Michigan were surveyed regarding any ERI's …


The Effects Of Two Group Counseling Interventions On Arab-American High School Students' Perceptions Of Their Primary Relationships (Parent, Teacher, Peer), Nuzmeya Bader Elder Jan 2012

The Effects Of Two Group Counseling Interventions On Arab-American High School Students' Perceptions Of Their Primary Relationships (Parent, Teacher, Peer), Nuzmeya Bader Elder

Wayne State University Dissertations

This study specifically investigated the effects of two group counseling interventions on Arab-American high school students' perceptions of the strength of their primary relationships (parent, teachers, and peers). It was designed to help high school students increase their acceptance of the culture of their host society and develop a sense of comfort so they can retain some of their own culture and Arab identity without feeling they will totally lose them. One approach was Choice group theory grounded in the reality of making choices concerning thoughts and behaviors. Choice Theory is described as the idea that people have mental images …


A Higher Education Case: Millennial Experience Toward Learning Through A Virtual World Designed As An Authentic Learning Environment, Marija Franetovic Jan 2012

A Higher Education Case: Millennial Experience Toward Learning Through A Virtual World Designed As An Authentic Learning Environment, Marija Franetovic

Wayne State University Dissertations

Current educational initiatives encourage the use of authentic learning environments to realistically prepare students for jobs in a constantly changing world. Many students of the Millennial generation may be social media savvy. However, what can be said about learning conditions and student readiness for active, reflective and collaborative learning and media literacy within their discipline? Virtual worlds such as Second Life (SL) represent future hybridized work environments which can support authentic learning. With their immersive and interaction affordances, virtual worlds may be designed to incorporate real-world team projects for both online and blended courses.

This qualitative single embedded case study …


Hallowed Ground: Literature And The Encounter With God In Post-Reformtion England, C. 1550 - 1704, Michael Thomas Martin Jan 2012

Hallowed Ground: Literature And The Encounter With God In Post-Reformtion England, C. 1550 - 1704, Michael Thomas Martin

Wayne State University Dissertations

This dissertation examines the ways in which the encounter with God is figured in post-Reformation English writing between the years 1550 and 1704. The introduction contextualizes the ways in which individuals might encounter God within cultural and historical circumstances of the period: the gradual disappearance of the tradition of spiritual direction that accompanied the suppression of Catholicism in England during the period and the growing influence of more purely "scientific" modes of inquiry, especially after Descartes. Because of these changes, the ways the encounter with God could be experienced were also changing. The introduction also shows how developments in religious …


Immigrant Integration Into Host Societies: The Case Of Yemeni Immigrant Communities In Metro Detroit, Samra Abdulla Nasser Jan 2012

Immigrant Integration Into Host Societies: The Case Of Yemeni Immigrant Communities In Metro Detroit, Samra Abdulla Nasser

Wayne State University Dissertations

This study is intended to extend our understanding of immigrant political integration by analyzing Yemeni immigrants' attitudes toward integration into North American society, exploring the case of Yemeni-Americans, a group reputedly resistant to integration, in both Dearborn and Hamtramck, Michigan, and comparatively assessing those data with already published data on Lebanese-Americans, retrieved from the U.S. Census Bureau and the Detroit Arab American Study (DAAS). Relying on an existing theoretical framework on immigrant integration based on sociological and cognitive approaches and my own theoretical model on transnational dimensions related to political, economic, and cultural integration, I will examine a series of …


Making Mathematics Matter: Professional Development Improving Outcomes In High-Poverty Environments, Carolyn A. Siebers Jan 2012

Making Mathematics Matter: Professional Development Improving Outcomes In High-Poverty Environments, Carolyn A. Siebers

Wayne State University Dissertations

This research study is a mixed – methods quantitative and qualitative study that analyzed data from an intensive, long – term professional development project named, " Project : Making Mathematics Matter. (PM3) " carried out in two low – performing, high – poverty districts. Two of the districts served as treatment districts and ALL teachers (general education, special education, ELL) who taught mathematics to students in grades 4-8 participated in a four-year PM3 mathematical intervention.

Three elements identified in the research as effective components in mathematics professional development served as foundational for this project. They were: teachers …


The Mental Model Comparison Of Expert And Novice Performance Improvement Practitioners, Sacip Toker Jan 2012

The Mental Model Comparison Of Expert And Novice Performance Improvement Practitioners, Sacip Toker

Wayne State University Dissertations

The primary purpose of this study was to reveal performance improvement practitioner expert and novice mental models and identify differences and similarities between these models. The secondary purpose was to analyze the potential relationships of the professional profile characteristics of performance improvement practitioners with their mental model of expertise derived from Pathfinder scaling algorithm. The study was stemmed from one of the critical research trends in the field of Human Performance Technology (HPT).

There are two phases of the study. In the first round of the first phase, experts, who were selected based on several criteria, were contacted to identify …


Multi-Fuel Operation Of Modern Engines; On Board Fuel Identification, Florin Mocanu Jan 2012

Multi-Fuel Operation Of Modern Engines; On Board Fuel Identification, Florin Mocanu

Wayne State University Dissertations

Modern engines require enhancement of electronic controls to achieve better fuel economy, higher power density and satisfactory emissions levels while operating safely.

Military vehicles should be capable to run safely and efficiently on any fuel available in the field, therefore on-board fuel identification and adaptation of engine controls to the type of fuel becomes extremely important. In these conditions, the use of an inexpensive, nonintrusive sensor is highly desirable.

The development of a technique based on the measurement of the instantaneous crankshaft speed and engine dynamics could be a convenient solution.

Several such methods have been elaborated at the Center …


Optical Investigation Of Ethanol And N-Heptane Dual-Fuel Partially Premixed Combution In S Reciprocating Engine, Radu Catalin Florea Jan 2012

Optical Investigation Of Ethanol And N-Heptane Dual-Fuel Partially Premixed Combution In S Reciprocating Engine, Radu Catalin Florea

Wayne State University Dissertations

The details of the dual-fuel combustion of n-heptane and ethanol were investigated in an optically accessible engine representative of light-duty applications. Experimental work involved the application of optical diagnostics such as high-speed imaging of combustion chemiluminescence and soot radiation, spectral measurements and laser induced fluorescence. At the same time, the experimental conditions have been replicated using numerical simulation of chemically reactive in-cylinder flow.

The numerical simulation results, which showed good agreement with the experimental data across several validation approaches, provided an improved understanding of the mechanism responsible for the control of the rate of combustion for dual-fuel operation. The comparison …


Epistemic Communities And Regional Governance: Policy Development In Municipal Finance Reform, Shanthi Karuppusamy Jan 2012

Epistemic Communities And Regional Governance: Policy Development In Municipal Finance Reform, Shanthi Karuppusamy

Wayne State University Dissertations

In recent times, the US has undergone significant changes in how regional governance is conceptualized and the focus has shifted from government to governance and from governmental consolidation to problem solving (Barnes and Foster, 2011). Policy makers' quest for interjurisdictional responses to the financial crisis and the recession has rekindled interest in the topic of regional governance. However, the economic, social and technical changes of the recent decades, which have now assimilated in US urban regions, fundamentally challenge existing dominant ways of thinking about regional governance and call for more useful analytic frameworks (Bollens, 1997; Barnes and Foster, 2011). This …


Estimating The Efficiency Of Michigan's Rural And Urban Public School Districts, Rita Ann Maranowski Jan 2012

Estimating The Efficiency Of Michigan's Rural And Urban Public School Districts, Rita Ann Maranowski

Wayne State University Dissertations

This study examined student achievement in Michigan public school districts to determine if rural school districts are demonstrating greater financial efficiency by producing higher levels of student achievement than school districts in other geographic locations with similar socioeconomics. Three models were developed using multiple regression analysis of student achievement for high school graduation rates and student proficiency rates for eleventh grade students in mathematics and English language arts as reported from the Michigan Merit Examination results. These models compared student achievement by geographic location which included a selection of 10 independent variables and a sample size of 496 Michigan public …


Identifying Sm22 As A Key Player In Arterial Diseases, Jianbin Shen Jan 2012

Identifying Sm22 As A Key Player In Arterial Diseases, Jianbin Shen

Wayne State University Dissertations

Background : Expression of vascular smooth muscle cell (VSMC) cytoskeleton markers including SM22 is down-regulated in arterial diseases including atherosclerosis where inflammation and osteochondrogenesis are present. However, the role of this downregulation in arterial pathogenesis is unknown. Hypothesis : Downregulation of SM22 may actively contribute to arterial pathogenesis. Methods : Five Sm22 knockout (Sm22-/-) mice and their wild type littermates were subjected to carotid artery denudation, an artery injury model. Analyses were conducted on carotid arteries 2 weeks after injury. Primary VSMCs were isolated from mouse aortas and investigated individually at passage 2 to 4. Sm22 knockdown was …


Determinants Of Cns Adult Neurogenesis Are Sex, Hormones, Mouse Strain, Age, And Brain Region, Carrie Lynn Tatar Jan 2012

Determinants Of Cns Adult Neurogenesis Are Sex, Hormones, Mouse Strain, Age, And Brain Region, Carrie Lynn Tatar

Wayne State University Dissertations

Multiple sclerosis is a sexually dimorphic (SD) disease that causes oligodendrocyte death but SD of glial cells is poorly studied. Here, we analyze SD of neural progenitors in 6-8wk and 6-8mo normal C57BL/6, SJL/J and BALB/c mice in the subventricular zone (SVZ), dorsolateral horn (DLC), corpus callosum (CC), and parenchyma. With a short 2 h BrdU pulse, no gender and strain differences are present at 6-8wk. At 6-8mo, the number of BrdU+ cells decreases 2-fold in both sexes, strains and regions indicating a common aging mechanism regulates BrdU incorporation. Strikingly, 2X more BrdU+ cells are found in all brain regions …


Robustness Of The Achievable Benchmark Of Care Method, Jeff Arthur Capobianco Jan 2012

Robustness Of The Achievable Benchmark Of Care Method, Jeff Arthur Capobianco

Wayne State University Dissertations

The Achievable Benchmark of Care Method is a process of care performance improvement measurement approach for identifying top performing healthcare providers. The purpose of this study was to investigate the robustness of the method. This was achieved by comparing the robustness of the standard ABC method, which uses the mean to calculate the benchmark, to versions of the ABC method where the mean was replaced with either a 5%, 10%, or 20% trimmed mean, a 15% Winsorized mean or the one-step Huber ø1.28 calculation. Monte Carlo simulations where conducted using publically available, Medicare process of care data. The mean was …


Toward An Applied Communication Relational Inqueery: Autoethnography, Co-Constructed Narrative, And Relational Futures, Derek M. Bolen Jan 2012

Toward An Applied Communication Relational Inqueery: Autoethnography, Co-Constructed Narrative, And Relational Futures, Derek M. Bolen

Wayne State University Dissertations

Born out of my personal relationships with others and the field of communication, particularly as it overlaps and intersects with the field of personal relationship research, this project begins with an exploration of research practices personal relationship inquiry, offers a queer critique on research and relating, and forwards a queer applied communication approach--relational inqueery. This dissertation was directed by three goals: (a) creating a space and terrain for queer relationships in the study of personal relationships and relational communication, (b) founding and beginning to further a field of relational inqueery, and (c) offering an applied communication approach within queer relational …


Inequality In Health Care Utilization And Equity: A Cross-Country Comparision Of Low And Middle Income Countries, Satis Chandra Devkota Jan 2012

Inequality In Health Care Utilization And Equity: A Cross-Country Comparision Of Low And Middle Income Countries, Satis Chandra Devkota

Wayne State University Dissertations

This dissertation identifies the sustainable policies that can reduce disparity in health care utilization, education and income from the low and middle income countries represented by Albania, Nepal, Tajikistan and Tanzania. Concentration indices are used to calculate the income related inequality in health care utilization and education, and Gini index is used to calculate the inequality in income. Likewise, horizontal inequity index is used to test whether the principle of equal treatment for equal need and equal schooling for equal need is maintained in all countries under study. Finally, a mechanism is proposed for the first time in the literature …


Investigation Of The Absorptive Potential Of Polymeric Nanoparticles Across The Lungs And Their Development For Efficient Systemic Delivery Following Pulmonary Administration, Abdul Khader Mohammad Jan 2012

Investigation Of The Absorptive Potential Of Polymeric Nanoparticles Across The Lungs And Their Development For Efficient Systemic Delivery Following Pulmonary Administration, Abdul Khader Mohammad

Wayne State University Dissertations

The lungs are an attractive route for drug delivery due to their high epithelial surface area available for absorption, a thin epithelium and extensive vasculature to name a few. Accordingly, a vast number of small molecule drugs, peptides, and proteins have been used to investigate their translocation across the lungs with many of the tested candidates showing excellent pharmacokinetics following pulmonary administration. Findings from all these studies over the years have strongly established the lungs as a route for drug delivery of small molecules and proteins. Nanoparticles on the other hand have gained increasing interest in drug delivery due to …


Identification Of Transcriptional Mechanisms Downstream Of Nf1 Gene Defeciency In Malignant Peripheral Nerve Sheath Tumors, Daochun Sun Jan 2012

Identification Of Transcriptional Mechanisms Downstream Of Nf1 Gene Defeciency In Malignant Peripheral Nerve Sheath Tumors, Daochun Sun

Wayne State University Dissertations

Malignant peripheral nerve sheath tumor (MPNST) is a type of soft tissue sarcoma that occurs in carriers of mutations in the neurofibromatosis type I gene (Nf1) as well as sporadically. Plexiform neurofibromas in NF1 patients have a significant risk of developing into MPNSTs leading to increased morbidity and mortality from this syndrome. Surgery is the primary intervention but it is not always effective due to the tendency of MPNSTs to infiltrate the surrounding tissue or grow in an inoperable location. Neurofibromin, the protein coded by the Nf1 gene, functions as a GTPase activating protein (GAP) whose mutation leads to constitutive …


Understanding The Gender-Based Mechanism Of Mso In Als Mice: A Metabolic Characterization Of The Sod1-G93a Mouse Model, Monica Ann Bame Jan 2012

Understanding The Gender-Based Mechanism Of Mso In Als Mice: A Metabolic Characterization Of The Sod1-G93a Mouse Model, Monica Ann Bame

Wayne State University Dissertations

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease characterized by motor neuron death and a corresponding loss of neuromuscular connections resulting in muscle atrophy. Patients become paralyzed shortly after symptom onset and typically die within one to five years of pulmonary complications. ALS is a relatively rare disease, with an overall incidence of approximately 2 in 100,000 people per year and a prevalence of about 5 in 100,000 people. It is typically associated with increasing age and has a slight male prevalence, with a male to female ratio of approximately 3:2. ALS is classified as either familial (the less …


Examining Autoimmune Sequelae During Cancer Immunotherapy In A Combined Autoimmune Thyroiditis And Tumor Mouse Model, Suresh Kari Jan 2012

Examining Autoimmune Sequelae During Cancer Immunotherapy In A Combined Autoimmune Thyroiditis And Tumor Mouse Model, Suresh Kari

Wayne State University Dissertations

Some clinical trials of immunotherapeutic agents against cancers have resulted in the development of autoimmune sequelae, including autoimmune thyroiditis. It has been suggested that the immunotherapy resulted in an alteration in the immunoregulatory mechanism(s). Using experimental autoimmune thyroiditis (EAT), a mouse model of Hashimoto's thyroiditis (HT), the importance of regulatory T cells (Tregs) has been well established; inhibition of Tregs leads to enhanced thyroiditis with repeated doses of mouse thyroglobulin (mTg) without adjuvant. To simulate cancer patients, we developed a combined EAT and tumor model in our EAT-susceptible mice (CBA/J). In first establishing the tumor model, we found Treg depletion …


Multifunctional Bioreducible Nanoparticles For Gene Therapy, Jing Li Jan 2012

Multifunctional Bioreducible Nanoparticles For Gene Therapy, Jing Li

Wayne State University Dissertations

Gene therapy is a promising therapeutic strategy to treat diseases caused by single or multiple gene mutations. Non-viral gene delivery vectors exhibit many advantages over viral vectors, including enhanced safety, versatility in choosing different types of therapeutic nucleic acids, and ease of formulation. However, low transgene efficiency and lack of targeting ability remain major challenges. Bioreducible polyplexes (polyelectrolyte complexes of disulfide-containing polycations and nucleic acids) utilize the redox potential gradient existing between extracellular space and intracellular environment as a physiological stimulus to enhance delivery of therapeutic nucleic acids to the subcellular space. Bioreducible containing polyplexes undergo intracellular reduction mediated GSH, …


A Multi-Agent Intelligent System For Detecting Unknown Adverse Drug Reactions Through Communication And Collaboration, Ayman Mohammad Mansour Jan 2012

A Multi-Agent Intelligent System For Detecting Unknown Adverse Drug Reactions Through Communication And Collaboration, Ayman Mohammad Mansour

Wayne State University Dissertations

Several thousands of drugs are currently available on the U.S. market. A complete understanding of the safe use of drugs is not possible at the time when drug is developed or marketed. At that time, the safety information is only obtained from a few thousand people in a typical pre-marketing clinical trial. Clinical trials are not capable of detecting rare adverse drug reactions (ADRs) because of limitations in sample size and trial duration. Early detection of unknown ADRs could save lives and prevent unnecessary hospitalizations. Current methods largely rely on spontaneous reports which suffer from serious underreporting, latency, and inconsistent …


Systems Support For Genomics Computing In Cloud Environments, Tung Thanh Nguyen Jan 2012

Systems Support For Genomics Computing In Cloud Environments, Tung Thanh Nguyen

Wayne State University Dissertations

Genomics research has enormous applications in many areas such as health care, forensic, agriculture, etc. Most recent achievements in this field come from the availability of the unprecedented genomic data. However, new sequencing technologies in genomics keep producing data at a faster pace resulting a very huge amount of data. This poses great challenges on how to store, manage, process and analyze the data efficiently. To deal with these, genomics research groups often equip themselves with a small scale server room composed of high storage capacity and computing ability machines. This solution is not only costly, unscalable but also inefficient. …


Role Of Thromboxane Receptor-Alpha In Prostate Cancer Progression, Prasanna Ekambaram Jan 2012

Role Of Thromboxane Receptor-Alpha In Prostate Cancer Progression, Prasanna Ekambaram

Wayne State University Dissertations

Thromboxane A2 (TXA2) is a major arachidonic acid metabolite that signals through TXA2 receptors (TP) to induce platelet aggregation and smooth muscle contraction. TXA2 receptors are expressed as two different isoforms in humans, namely TP-alpha (TPα) and TP-beta (TPβ), which have common and distinct signaling pathways. Of the two TP receptor isoforms, studies have shown that TPα impacts tumor growth and progression of lung cancer. Previously our studies demonstrated that activation of Thromboxane receptor by TXA2 agonists could regulate prostate cancer (PCa) cell motility and cytoskeletal reorganization through activation of Rho-A. The primary objective of this study is to investigate …


Membrane-Bound Immunomodulators As Adjuvants In A Cell Culture-Based Avian Influenza Vaccine, David Daniel Fischer Jan 2012

Membrane-Bound Immunomodulators As Adjuvants In A Cell Culture-Based Avian Influenza Vaccine, David Daniel Fischer

Wayne State University Dissertations

Inactivated viral vaccines often generate suboptimal immune responses. Adjuvants are incorporated into vaccines to increase their immunogenicity, however currently available adjuvants have shortcomings which have limited their use in human and veterinary medicine. This necessitates the development of new adjuvants and delivery systems. Cytokines have been extensively tested as adjuvants in vaccines but challenges such as diffusion from antigen, short half-lives and production costs have been encountered. To address this, we developed a technology that efficiently produces inactivated, whole-virus influenza vaccine bearing membrane-bound cytokines. Tethering the cytokine to the antigen of interest keeps the immunomodulator in close contact with the …


Narratives Of Possibility: Adolescent Girls Constructing And Negotiating Front And Back Stage Identities Through Blogs, Kattie Marie Hogan Jan 2012

Narratives Of Possibility: Adolescent Girls Constructing And Negotiating Front And Back Stage Identities Through Blogs, Kattie Marie Hogan

Wayne State University Dissertations

For young woman, the issue of self-expression is important to consider because there are many contexts where their voices and experiences are discounted, silenced, and suppressed. Venues for self-expression can provide a way for those voices and experiences that have been ignored in classrooms and other social outlets to be recognized. This research study explored the ways four girls between the ages of 16-19 used blogging to construct meaning of their experiences and negotiate their identities through a wide range of literary practices including nonfiction and fiction writing, photographs, self-created drawings, and other materials. Writing in these blogs girls moved …