Digital Commons Network^™

Lipid Rafts Alter The Stability And Activity Of The Cholera Toxin A1 Subunit, Supriyo Ray, Michael Taylor, Tuhina Banerjee, Suren A. Tatulian, Ken Teter

Faculty Bibliography 2010s

Cholera toxin (CT) travels from the cell surface to the endoplasmic reticulum (ER) as an AB holotoxin. ER-specific conditions then promote the dissociation of the catalytic CTA1 subunit from the rest of the toxin. CTA1 is held in a stable conformation by its assembly in the CT holotoxin, but the dissociated CTA1 subunit is an unstable protein that spontaneously assumes a disordered state at physiological temperature. This unfolding event triggers the ER-to-cytosol translocation of CTA1 through the quality control mechanism of ER-associated degradation. The translocated pool of CTA1 must regain a folded, active structure to modify its G protein target …

Investigating Gender Differences In Student Preferences For And Achievement With Educational Games, Damon A. Regan

Electronic Theses and Dissertations

The purpose of this study was to investigate the choice behavior and achievement of male and female high school students who are given an option of taking a 36 week American History course in either a game-based format or a web-based format. It was hypothesized that (a) males would enroll more frequently in the game-based course than females, (b) there would be no significant difference in achievement between males and females in the game-based course or across course formats, and (c) there would be no significant interaction between gender and the selection of course format. The study consisted of a …

Intellectual Property Rights (Ipr) Disputes In Cyberspace: U.S. Hegemony And Chinese Resistance, Dexin Tian, Chin-Chung Chao

Communication Faculty Publications

This paper aims at explicating the hegemonic pressure from the U.S. side and the constant resistance from the Chinese side during the U.S.-China IPR disputes in the cyberspace. The theory of hegemony and extended literature review reveal that during the U.S.-China IPR disputes in cyberspace, the dominant U.S. power has shaped the IPR world order so effectively for its own interests that China as a disadvantaged country has been included, albeit with reservations, in the broad consent of the U.S. hegemonic sphere of influence. This study has also demonstrated significant theoretical and practical implications.

Performing Community: The Place Of Music, Race And Gender In Producing Appalachian Space, Deborah J. Thompson

Theses and Dissertations--Geography

Traditional, participatory music is a powerful medium through which people express and shape their ideas about identity, mobility, social relations, and belonging, and through which people are in turn shaped. The everyday cultural practices of playing, sharing, and dancing to traditional music, as well as discussions about the nature of traditional music and production of events involving traditional music, all work to construct the region called Appalachia.

Through this dissertation, I seek to answer some simple questions that have complicated answers involving place, identity, power, and social relations, with economic, social, and emotional ramifications: Who gets to be an Appalachian …

Contested Spaces In London: Exhibitionary Representations Of India, C. 1886-1951, Alayna Heinonen

Theses and Dissertations--History

Following the first world exhibition, the 1851 Crystal Palace Exhibition in London, exhibitions became routine events across the West that merged both education and entertainment to forward political and economic goals. For the most part scholars have taken the frequency, popularity, and propagandistic efforts of exhibitions at face value, viewing them as successful reassertions of the imperial, industrial, and technological superiority of Western nation-states. Though offering valuable insights into the cultural technologies of imperial rule, these works miss the complexities of imperial projects within specific temporal and geographical contexts.

This manuscript traces the historical dynamics of India at exhibitions held …

Faustian Figures: Modernity And Male (Homo)Sexualities In Spanish Commercial Literature, 1900-1936, Jeffrey Zamostny

Theses and Dissertations--Hispanic Studies

I contend in this study that commercial novels and theater from early twentiethcentury Spain often present male (homo)sexual characters as a point of constellation for anxieties regarding modernization in Madrid and Barcelona. In works by Jacinto Benavente, Josep Maria de Sagarra, El Caballero Audaz (José María Carretero), Antonio de Hoyos y Vinent, Carmen de Burgos, Álvaro Retana, Eduardo Zamacois, and Alfonso Hernández-Catá, concerns about technological and socioeconomic change converge upon hustlers and blackmailers, queer seducers, and chaste inverts. I examine these figures alongside an allegorical interpretation of Goethe’s Faust in Marshall Berman’s book All That is Solid Melts into Air: …

Investigating The Role Of Prion Protein Polymorphisms On Prion Pathogenesis, Eri Saijo

Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics

Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are lethal and infectious neurodegenerative diseases of humans and animals. The misfolding of the normal, or cellular isoform of the prion protein (PrP^C) into the abnormal disease-associated isoform of PrP (PrP^Sc) could change the properties of PrP, consequently, PrP^Sc has lethal infectivity to transmit diseases. The proteinaceous infectious particle consisting mainly of PrP^Sc is called prion. Transmissibility of prions is strongly influenced by multiple factors including PrP polymorphisms, species barriers (PrP sequence specificity) and prion strains (conformational specificity) by unknown mechanisms. Even though the ability …

Nanocrystals Of Chemotherapeutic Agents For Cancer Theranostics: Development And In Vitro And In Vivo Evaluation, Christin P. Hollis

Theses and Dissertations--Pharmacy

The majority of pharmacologically active chemotherapeutics are poorly water soluble. Solubilization enhancement by the utilization of organic solvents often leads to adverse side effects. Nanoparticle-based cancer therapy, which is passively targeted to the tumor tissue via the enhanced permeation and retention effect, has been vastly developed in recent years. Nanocrystals, which exist as crystalline and carry nearly 100% drug loading, has been explored for delivering antineoplastic agents. Additionally, the hybrid nanocrystal concept offers a novel and simple way to integrate imaging agents into the drug crystals, enabling the achievement of theranostics. The overall objective of this dissertation is to formulate …

Cross-Cultural Comparison Of Perceptions About School Feeding Programs From Ghanaian And U.S. Adults, Yolanda L. Jackson

Theses and Dissertations--Nutrition and Food Systems

Because of an increase in food insecurity over the past decade, the U.S. and many developing countries are focusing efforts on issues relating to child hunger. School feeding programs have been in existence for roughly 220 years but modifications have been made over the years to improve the quality of food they serve. Little research has been conducted about adult perceptions of school feeding programs and the impact it has on the community in the U.S. as well as developing countries such as Ghana, West Africa. Because of the gap in literature on school feeding programs and adult perceptions about …

Dordt College 2012-13 Catalog, Dordt College. Registrar's Office

Academic Catalogs

Academic Catalog for 2012-13

Sex Trafficked Survivors' Recovery: Program Evaluation Of Transitions Global Cambodian Safe House , Robyn J. Honeycutt

Doctor of Psychology (PsyD)

No abstract provided.

Resilience In Cambodia: Hearing The Voices Of Trafficking Survivors And Their Helpers , Glori G. Gray

Doctor of Psychology (PsyD)

No abstract provided.

Mexican-Americans In Los Angeles: Strengthening Their Ethnic Identity Through Chivas Usa, Stephanie Goldberger

CMC Senior Theses

A large Mexican-American population already exists in Los Angeles and, with each generation, it continues to rise. This Mexican-American community has maintained its connection to its heritage by playing and watching soccer, Mexico’s top watched sport. In this thesis, I analyze how Major League Soccer's Chivas USA serves as an outlet through which many Mexicans in Los Angeles have developed their ethnic identities. Since the early twentieth century, Mexicans in Los Angeles have created separate residential communities and sports organizations to strengthen their connections with one another.

To appeal to Mexican-Americans, Chivas USA has branded itself closely to its sister …

Vanishing Acts: Creative Women In Spain And The United States, Jean M. Grow, David Roca, Sheri J. Broyles

College of Communication Faculty Research and Publications

This exploratory cross-cultural study examines the experiences of women in advertising creative departments in Spain and the United States. The study, an exploration of the creative environment and its impact on female creatives, is framed by Hofstede’s dimensional model of national culture (Hofstede 2001; de Mooij & Hofstede 2010) and signalling theory (Spence 1974). Interviews with 35 top female creatives suggest that the challenges women face are rooted in the ‘fraternity culture’ or ‘territorio de chicos’ of creative departments in both countries. The data further suggest that the gender-bound cultural environment of advertising creative departments may be a global phenomenon, …

When Indian Women Text Message: Culture, Identity, And Emerging Interpersonal Norms Of New Media, Robert Shuter

College of Communication Faculty Research and Publications

No abstract provided.

Book Review Of The Listener's Voice: Early Radio And The American Public, Amanda R. Keeler

College of Communication Faculty Research and Publications

No abstract provided.

The Gendered Body In Virtual Space : Sexuality, Performance And Play In Four Second Life Spaces, Judith Elund

Theses: Doctorates and Masters

This work is principally an investigation into visual and screen culture, using four specific regions of the three-dimensional virtual world of ‘Second Life’ as case studies. The analysis follows a thematic application of discourse analysis as a basis for critiquing Western screen culture, most importantly the cultural and social conditions that replicate dominant paradigms of power and agency. Of particular pertinence to this study are the framing, representational and spatial practices of gendered and sexual identities within ‘Second Life’ spaces. As is typical of the internet, sexual freedom is a given, yet representational performance (how one appears through their embodied …

Climate Change, Political Truth, And The Marketplace Of Ideas, Karl S. Coplan

Elisabeth Haub School of Law Faculty Publications

In a recent interview in Time magazine, EPA administrator Lisa Jackson commented on congressional efforts to undo her greenhouse gas endangerment finding under Clean Air Act section 202: “I don't think that history will forget the first time that politicians made a law to overrule scientists.” Proponents of aggressive action to control greenhouse gases are frustrated that the international scientific consensus that disruptive climate change is highly probable and caused by anthropogenic emissions has not prevailed in the political marketplace of ideas in the United States. This truth-seeking, open marketplace of ideas is not just a recognized foundational principle in …

Intercultural New Media Studies: The Next Frontier In Intercultural Communication, Robert Shuter

College of Communication Faculty Research and Publications

New media (ICT's) are transforming communication across cultures. Despite this revolution in cross cultural contact, communication researchers have largely ignored the impact of new media on intercultural communication. This groundbreaking article defines the parameters of a new field of inquiry called Intercultural New Media Studies (INMS), which explores the intersection between ICT's and intercultural communication. Composed of two research areas—(1) new media and intercultural communication theory and (2) culture and new media—INMS investigates new digital theories of intercultural contact as well as refines and expands twentieth-century intercultural communication theories, examining their salience in a digital world. INMS promises to increase …

The Impact Of Dakota Missions On The Development Of The U.S.-Dakota War Of 1862, Daphne D. Hamborg

All Graduate Theses, Dissertations, and Other Capstone Projects

This thesis explores the relationships between three groups of people on the mid-nineteenth century Minnesota frontier: evangelical Protestant missionaries, the Dakota who converted to the Christian faith and lifestyle taught by these missionaries, and the Dakota who remained traditional in their outlook and lifestyle. It does this through an analysis of the impact of these relationships on the development of the U.S.-Dakota War of 1862. As is made clear through the use of both primary and secondary sources, the missionaries helped create tensions within the Dakota community, tensions expressed through shifting social structures, argument, alienation, and, at times, violence. As …

Deconstructing "Chappelle's Show": Race, Masculinity,And Comedy As Resistance, Lyndsey Lynn Wetterberg

All Graduate Theses, Dissertations, and Other Capstone Projects

"Chappelle's Show" is a sketch comedy series that ran from 2003-2004 and that was created by and starred comedian Dave Chappelle. Chappelle focused on the issues of racism and race as gendered and as a social construction throughout the show's two full seasons. Using content analysis, my research highlights race and masculinity as a social construction within the context of "Chappelle's Show" by focusing on specific sketches within the series that play on issues of race and gender. The overarching theme of my analysis examines the idea of comedy as resistance to dominant society, specifically to race and gender norms …

Diversity And The Virtual Workplace: Performance Identity And Shifting Boundaries Of Workplace Engagement, Natasha T. Martin

Faculty Articles

This article explores the meaning of workplace discrimination where reality meets the imaginary world in virtual work settings. Using a more recent development in the realm of virtual work--workplace avatars--the article considers the impact on law of virtual performance identity by workers where appearances can be altered in virtual reality.

Current protected-class approaches to antidiscrimination law have not served as the antidote to workplace bias and exclusion. Thus, the article investigates whether avatar technology holds promise for facilitating greater inclusion of marginalized workers in the contemporary workplace. Does this mode of virtual work serve as a platform for diversity or …

Climate Change, Political Truth, And The Marketplace Of Ideas, Karl S. Coplan

Utah Law Review

In an interview last year in Time magazine, Environmental Protection Agency (EPA) Administrator Lisa Jackson commented on congressional efforts to undo her greenhouse gas (GHG) endangerment finding under Clean Air Act section 202: “I don’t think that history will forget the first time that politicians made a law to overrule scientists.” Proponents of aggressive action to control GHGs are frustrated that international scientific consensus that disruptive climate change is highly probable and caused by anthropogenic emissions has not prevailed in the political marketplace of ideas in the United States. This truth-seeking, open marketplace of ideas is not just a recognized …

The Right Of Publicity In New York And California: A Critical Analysis, Paul Czarnota

Jeffrey S. Moorad Sports Law Journal (1994 - )

The article provides an analysis of the right of publicity under the state laws of New York and California as of September 2012, focusing on the application of the laws to celebrities and the illegal use of their identities in advertising and trade. The New York right to publicity tort laws reportedly protect a celebrity's name, portrait, and voice from unauthorized use by third parties. The New York case Roberson v. Rochester Folding Box Co. is also mentioned.

Bgsu Graduate College 2012-2013 Catalog, Bowling Green State University

Course Catalogs

Bowling Green State University graduate catalog for 2012-2013

Bibliography Of Central European Women's Holocaust Life Writing In English, Louise O. Vasvári

CLCWeb Library

No abstract provided.

Pegylated Arginine Deiminase Downregulates Colitis In Murine Models, Helieh S. Oz, Jian Zhong, Willem J. S. De Villiers

Physiology Faculty Publications

Arginine deiminase (ADI), an arginine-metabolizing enzyme involved in cell signaling, is dysregulated in multiple inflammatory diseases and cancers. We hypothesized that pegylated ADI (ADI-PEG) provide protection against colitis.

METHODS: Dextran sodium sulfate colitis was induced in IL-10-deficient and BALB/c (WT) mice. ADI-PEG was administered i.p., and inflammatory mediators and pathology were evaluated.

RESULTS: Acute colitis in mice was manifested by increases in inflammatory biomarkers, such as serum amyloid A (SAA, P < 0.001), IL-12 p40, and disease index (3-Fold). In contrast, ADI-PEG significantly decreased clinical disease index, SAA levels, and inflammatory cytokines in blood as well as in colonic explants. Animals developed moderate (2.2 ± 0.3 WT) to severe (3.6 ± 0.5 IL-10 deficient) colonic pathology; and ADI-PEG treatment significantly improved the severity of colitis (P < 0.05). Marked infiltration of CD68+ macrophages and iNOS expression were detected in colonic submucosa in colitic animals but not detected in ADI-PEG-treated animals.

CONCLUSION: ADI-PEG attenuated inflammatory responses by suppression of macrophage infiltration and iNOS expression in colitic animals. ADI-PEG can serve as a potential therapeutic value in IBD.

Chilean Cultural Identity: A Case Study Of Contemporary Mapuche Poetry, La Identidad Cultural Chilena: Un Caso De Estudio De La Poesía Mapuche Contemporánea, Christopher Culbertson

Senior Independent Study Theses

The topic is approached in three different manners: hybrid theory, academic perspectives, and poetry analysis. An application of hybrid theory facilitates the understanding of cultural identity within Chile. A discussion by three Chilean professors reveals the important themes of geographic location, generation, and language in both the production and reception of written contemporary Mapuche poetry. An analysis of selected of written Mapuche poetry depicts the unique conceptualizations of identity by contemporary Mapuche poets. As a result, this independent study shows how written contemporary Mapuche poetry is an appropriate indicator of the evolution of Mapuche hybrid identity.

Intervention: Reality Tv, Whiteness, And Narratives Of Addiction, Jessie Daniels

Publications and Research

Purpose – Reality TV shows that feature embodied “transformations” are popular, including Intervention, a program that depicts therapeutic recovery from addiction to “health.” The purpose of this chapter is to address the ways whiteness constitutes narratives of addiction on Intervention.

Methodology – This analysis uses a mixed methodology. I conducted a systematic analysis of nine (9) seasons of one hundred and forty-seven (147) episodes featuring one hundred and fifty-seven individual “addicts” (157) and logged details, including race and gender. For the qualitative analysis, I watched each episode more than once (some, I watched several times) and took extensive notes on …

Formalism In The Music Theory Classroom, Roger Mathew Grant

Journal of Music Theory Pedagogy

Music theory pedagogy has anticipated the recent trend for alternatives to the careful historicism and contextual scholarship of the past few decades. In recent years, many scholars in the fields of literature and the arts have urged a reinvestment in the study of form and in formalist analysis. This "New Formalism" employs a diverse array of methods in order to redress a perceived neglect of the forms, styles, techniques, and material dimensions of the cultural products under consideration. Although some of our methods have changed, theorists remain committed to the technical vocabulary and formal abstraction necessary to understand musical systems. …