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2012

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A Symbiotic View Of Life: We Have Never Been Individuals, Scott F. Gilbert, J. Sapp, A. I. Tauber Dec 2012

A Symbiotic View Of Life: We Have Never Been Individuals, Scott F. Gilbert, J. Sapp, A. I. Tauber

Biology Faculty Works

The notion of the "biological individual" is crucial to studies of genetics, immunology, evolution, development, anatomy, and physiology. Each of these biological subdisciplines has a specific conception of individuality, which has historically provided conceptual contexts for integrating newly acquired data. During the past decade, nucleic acid analysis, especially genomic sequencing and high-throughput RNA techniques, has challenged each of these disciplinary definitions by finding significant interactions of animals and plants with symbiotic microorganisms that disrupt the boundaries that heretofore had characterized the biological individual. Animals cannot be considered individuals by anatomical or physiological criteria because a diversity of symbionts are both …

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Review Of "Fifty Animals That Changed The Course Of History" By E. Chaline, John B. Jenkins Dec 2012

Review Of "Fifty Animals That Changed The Course Of History" By E. Chaline, John B. Jenkins

Biology Faculty Works

No abstract provided.

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How Crucial Are Multi-Cultural Texts To Social Awareness And Acceptance In The Universal Pre-Kindergarten Setting?: A Study On Views On Family Structure, Elisabeth Addyman Dec 2012

How Crucial Are Multi-Cultural Texts To Social Awareness And Acceptance In The Universal Pre-Kindergarten Setting?: A Study On Views On Family Structure, Elisabeth Addyman

Education Masters

This study examined the impact that multi-cultural picture books have on students’ views on different family structures in the Universal Pre-Kindergarten setting. Research was conducted in a Universal Pre-Kindergarten classroom in a whole and small group setting. Data was collected through informal observations, student work, and pre and post interviews. The findings showed that the students could benefit greatly from multi-cultural picture books when coupled with meaningful discussions and/or extending activities. In order to determine the full potential of using multi-cultural picture books within the classroom to impact students’ views on different family structures, more research needs to be conducted.

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The Impact Of Student Interest And Instructor Effectiveness On Student Performance, Kate Sauer Dec 2012

The Impact Of Student Interest And Instructor Effectiveness On Student Performance, Kate Sauer

Education Masters

This research project began by asking if and how student interest and instructor effectiveness impacted student performance. Research was conducted with two middle school students. The data was gathered by administering questionnaires, collecting student work, and recording observations. Findings revealed that students’ interest and their relationship with the instructor were contributing factors in successful academic performance. Therefore, the data implied that teachers need consider student interest and develop a relationship with them in order to foster student growth and success.

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Using Technology As A Teacher Differentiation Tool To Increase Students' High Frequency Word Recognition, Shannon Mclaughlin Dec 2012

Using Technology As A Teacher Differentiation Tool To Increase Students' High Frequency Word Recognition, Shannon Mclaughlin

Education Masters

This research asked, “how does technology, as a teacher assistive differentiation tool, increase students high frequency word recognition?” Research was conducted in Greenville, New York with a group of nine first grade students all classified with a disability. Students were placed in either an iPad or flash card group. Quantitative and qualitative data was collected through questionnaires/interviews, student observations, and assessment. Findings revealed that both the groups increased their word recognition; however, the iPad group revealed a greater percentage increase when compared to the flash card group. The data implies there is a correlation among students with disabilities and using …

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Characterization Of Novel Extracellular Matrix (Ecm) Proteins (Mgp And Lumican) And Their Implications In Vascular Development, Angiogenesis, And Cancer, Bikram Sharma Dec 2012

Characterization Of Novel Extracellular Matrix (Ecm) Proteins (Mgp And Lumican) And Their Implications In Vascular Development, Angiogenesis, And Cancer, Bikram Sharma

All-Inclusive List of Electronic Theses and Dissertations

No abstract provided.

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Zoomorphic Penannular Brooches In 6th And 7th Century Ireland, Esther G. Ward Dec 2012

Zoomorphic Penannular Brooches In 6th And 7th Century Ireland, Esther G. Ward

School of Art, Art History, and Design: Theses and Student Creative Work

In this thesis the author examines the evolution, manufacture, and societal significance of zoomorphic penannular brooches, a type of metal dress fastener used in early medieval Ireland that is often decorated. The brooches examined are dated to the 6th and 7th centuries, during which the Irish underwent a process of religious conversion from Celtic paganism to Christianity, and social rank was paramount. It is in this social context that the brooches are examined. Despite the significance of this time of social change, brooches from this period tend to be overlooked by scholarship in favor of the more ornate …

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Cd4+ Regulatory And Effector/Memory T Cell Subsets Profile Motor Dysfunction In Parkinson’S Disease, Jessica A. Hutter Saunders, Katherine A. Estes, Lisa M. Kosloski, Heather E. Allen, Kathryn Dempsey Cooper, Diego R. Torres-Russotto, Jane L. Meza, Pamela M. Santamaria, John M. Bertoni, Daniel L. Murman, Hesham Ali, David G. Standaert, R. Lee Mosley, Howard E. Gendelman Dec 2012

Cd4+ Regulatory And Effector/Memory T Cell Subsets Profile Motor Dysfunction In Parkinson’S Disease, Jessica A. Hutter Saunders, Katherine A. Estes, Lisa M. Kosloski, Heather E. Allen, Kathryn Dempsey Cooper, Diego R. Torres-Russotto, Jane L. Meza, Pamela M. Santamaria, John M. Bertoni, Daniel L. Murman, Hesham Ali, David G. Standaert, R. Lee Mosley, Howard E. Gendelman

Interdisciplinary Informatics Faculty Publications

Animal models and clinical studies have linked the innate and adaptive immune system to the pathology of Parkinson’s disease (PD). Despite such progress, the specific immune responses that influence disease progression have eluded investigators. Herein, we assessed relationships between T cell phenotype and function with PD progression. Peripheral blood lymphocytes from two separate cohorts, a discovery cohort and a validation cohort, totaling 113 PD patients and 96 age- and environment-matched caregivers were examined by flow cytometric analysis and T cell proliferation assays. Increased effector/memory T cells (Tem), defined as CD45RO+ and FAS+ CD4+ T cells and decreased CD31+ and α4β7+ …

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Competing Sovereignties: Corporate Social Responsibility, Oil Extraction, And Indigenous Subjectivity In Ecuador, Emily Billo Dec 2012

Competing Sovereignties: Corporate Social Responsibility, Oil Extraction, And Indigenous Subjectivity In Ecuador, Emily Billo

Geography and the Environment - Dissertations

Corporate social responsibility (CSR) programs developed in recent years as the business response to social and environmental criticism of corporate operations, and are most debated in those societies where neoliberalism emerged most prominently, the United States and the United Kingdom. My dissertation expands these debates investigating the CSR programs of a Spanish-owned multinational oil company, Repsol-YPF operating in the Ecuadorian Amazon region. It explores CSR programs as institutions that can facilitate ongoing resource extraction, and particular technologies of rule that serve to discipline indigenous peoples at the point of extraction. I conducted an institutional ethnography to examine the social relationships …

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Indigenous Peoples And Epistemic Injustice: Science, Ethics, And Human Rights, Rebecca Tsosie Dec 2012

Indigenous Peoples And Epistemic Injustice: Science, Ethics, And Human Rights, Rebecca Tsosie

Washington Law Review

This Article explores the use of science as a tool of public policy and examines how science policy impacts indigenous peoples in the areas of environmental protection, public health, and repatriation. Professor Tsosie draws on Miranda Fricker’s account of “epistemic injustice” to show how indigenous peoples have been harmed by the domestic legal system and the policies that guide the implementation of the law in those three arenas. Professor Tsosie argues that the theme of “discovery,” which is pivotal to scientific inquiry, has governed the violation of indigenous peoples’ human rights since the colonial era. Today, science policy is overtly …

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Pc-Based Automated Control System For Jordan Northern Grain Silo, Salem Al-Agtash Dec 2012

Pc-Based Automated Control System For Jordan Northern Grain Silo, Salem Al-Agtash

Computer Science and Engineering

This paper presents a PC-based automated control system operation of the Northern Grain Silo of Jordan. The system connects to a PLC (programmable logic controller) device, and combines operator interface, PLC programming and monitoring functions into one platform. The PLC portion handles direct operations control, while the PC portion handles interfacing and data intensive functions. A simulation package is developed. The package generates a graphical user interface for real-time graphic animations of the Grain Silo operation. We discuss anticipated benefits of such a system and phases of implementation.

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The Body Machinic: Technology, Labor, And Mechanized Bodies In Victorian Culture, Jessica Kuskey Dec 2012

The Body Machinic: Technology, Labor, And Mechanized Bodies In Victorian Culture, Jessica Kuskey

English - Dissertations

While recent scholarship focuses on the fluidity or dissolution of the boundary between body and machine, "The Body Machinic" historicizes the emergence of the categories of "human" and "mechanical" labor. Beginning with nineteenth-century debates about the mechanized labor process, these categories became defined in opposition to each other, providing the ideological foundation for a dichotomy that continues to structure thinking about our relation to technology. These perspectives are polarized into technophobic fears of dehumanization and machines "taking over," or technological determinist celebrations of new technologies as improvements to human life, offering the tempting promise of maximizing human efficiency. "The Body …

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The Risks Of Outsourcing Security: Foreign Security Forces In United States National Security Policy, Eric Rittinger Dec 2012

The Risks Of Outsourcing Security: Foreign Security Forces In United States National Security Policy, Eric Rittinger

Political Science - Dissertations

This study combines insights from international relations, diplomatic history, and civil-military relations to improve our understanding of the tenuous arrangement between the United States and its foreign military proxies. For over a century, the U.S. has armed and trained these proxies to assume responsibilities that its own military might otherwise have to bear. But throughout that time, critics have doubted whether the U.S. could or should delegate sensitive security responsibilities to "dubious" foreign soldiers. Such doubt highlights an international analog to the principal-agent problem normally associated with domestic civil-military relations. I examine why this international principal-agent problem arose, how it …

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Ecology Of Zoonoses: Natural And Unnatural Histories, William B. Karesh, Andy Dobson, James O. Lloyd-Smith, Juan Lubroth, Matthew A. Dixon, Malcolm Bennett, Stephen Aldrich, Todd Harrington, Pierre Formenty, Elizabeth H. Loh, Catherine C. Machalaba, Mathew Jason Thomas, David L. Heymann Dec 2012

Ecology Of Zoonoses: Natural And Unnatural Histories, William B. Karesh, Andy Dobson, James O. Lloyd-Smith, Juan Lubroth, Matthew A. Dixon, Malcolm Bennett, Stephen Aldrich, Todd Harrington, Pierre Formenty, Elizabeth H. Loh, Catherine C. Machalaba, Mathew Jason Thomas, David L. Heymann

United States Public Health Resources

More than 60% of human infectious diseases are caused by pathogens shared with wild or domestic animals. Zoonotic disease organisms include those that are endemic in human populations or enzootic in animal populations with frequent cross-species transmission to people. Some of these diseases have only emerged recently. Together, these organisms are responsible for a substantial burden of disease, with endemic and enzootic zoonoses causing about a billion cases of illness in people and millions of deaths every year. Emerging zoonoses are a growing threat to global health and have caused hundreds of billions of US dollars of economic damage in …

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Collaborating To Improve Inquiry-Based Teaching In Elementary Science And Mathematics Methods Courses, Paula A. Magee, Ryan Flessner Dec 2012

Collaborating To Improve Inquiry-Based Teaching In Elementary Science And Mathematics Methods Courses, Paula A. Magee, Ryan Flessner

Scholarship and Professional Work – Education

This study examines the effect of promoting inquiry-based teaching (IBT) through collaboration between a science methods course and mathematics methods course in an elementary teacher education program. During the collaboration, preservice elementary teacher (PST) candidates experienced 3 different types of inquiry as a way to foster increased understanding of inquiry based teaching (IBT). The experiences included a PST driven science inquiry and a mathematics inquiry where PSTs were learners and a science inquiry where PSTs were teachers. During and following the semester of the collaboration, data were collected to assess the impact of the inquiry experiences on the PSTs’ understanding …

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Leopold's Last Talk, Eric T. Freyfogle Dec 2012

Leopold's Last Talk, Eric T. Freyfogle

Washington Journal of Environmental Law & Policy

During the last decade of his life, Aldo Leopold (1887–1948) delivered more than 100 conservation talks to various popular, professional, and student audiences. In them, he set forth plainly the central elements of his conservation thought. By studying the extensive archival records of these talks one sees clearly the core elements of Leopold’s mature thinking, which centered not on specific land-use practices (good or bad), but instead on what he saw as deep flaws in American culture. Leopold’s sharp cultural criticism—more clear in these talks than in his lyrical, muted classic, A Sand County Almanac—called into question not just …

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Oil Development In Anwr: The Precautionary Principle Is Compatible With The Fish And Wildlife Service's Statutory Mandate, Trisna Tanus Dec 2012

Oil Development In Anwr: The Precautionary Principle Is Compatible With The Fish And Wildlife Service's Statutory Mandate, Trisna Tanus

Washington Journal of Environmental Law & Policy

The potential for oil production in the Arctic National Wildlife Refuge (ANWR) coastal plain, otherwise known as the 1002 Area, is significant, with a current value of $770 billion. Yet, there are considerable knowledge gaps and disagreements over the environmental impacts of oil development in ANWR. The Fish and Wildlife Service (FWS) manages ANWR and is tasked with advancing the refuge’s mission of ecological conservation. Before it can approve oil development in ANWR, the FWS is statutorily required to ensure that oil development is compatible with ANWR’s mission. This Comment argues that the precautionary principle is embedded within the laws …

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Tennessee Forestry Commission Fy 2012 Annual Report, Tennessee. Department Of Agriculture. Dec 2012

Tennessee Forestry Commission Fy 2012 Annual Report, Tennessee. Department Of Agriculture.

Forestry Commission Annual Report

No abstract provided.

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Causes And Effects Of Epithelial Morphogenesis In Pancreatitis And Pancreatic Cancer, Kathleen Elizabeth Delgiorno Dec 2012

Causes And Effects Of Epithelial Morphogenesis In Pancreatitis And Pancreatic Cancer, Kathleen Elizabeth Delgiorno

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease due to lack of early detection, making the study of initiating events, intrinsic and extrinsic, invaluable. An aberrant epithelial structure consistently associated with PDAC development is the metaplastic ductal lesion (MDL), formed as a result of acinar to ductal metaplasia (ADM) and hypothesized to be pre-neoplastic. Through lineage tracing and immunohistochemistry I have determined that MDLs derive from acinar cells that have converted to structures resembling the developmentally related biliary duct gland. Consistent with this process, MDLs co-express the transcription factors PDX1 and SOX17, a molecular signature reserved for pancreatobiliary progenitor …

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The Expressive Cost Of Corporate Immunity, Gregory M. Gilchrist Dec 2012

The Expressive Cost Of Corporate Immunity, Gregory M. Gilchrist

UC Law Journal

Is it possible to justify imposing criminal liability on corporations? Two basic aspects of criminal law have no application to corporations: Corporations cannot be jailed and they cannot form mental states. Moreover, there is reason to think that much of the deterrent effect generated by corporate criminal liability could be generated more efficiently by civil liability. Still, the demand for criminal prosecution of corporations remains high. This Article seeks to understand why we have corporate criminal liability, and it concludes that expressivism is necessary to justify the practice. Expressivism justifies punishment by reference to the benefits of a statement of …

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Nullomer Derived Anticancer Peptides (Nullops): Differential Lethal Effects On Normal And Cancer Cells In Vitro, Abdelkrim Alileche, Jayita Goswami, William Bourland, Mike Davis, Greg Hampikian Dec 2012

Nullomer Derived Anticancer Peptides (Nullops): Differential Lethal Effects On Normal And Cancer Cells In Vitro, Abdelkrim Alileche, Jayita Goswami, William Bourland, Mike Davis, Greg Hampikian

Biology Faculty Publications and Presentations

We demonstrate the first use of the nullomer (absent sequences) approach to drug discovery and development. Nullomers are the shortest absent sequences determined in a species, or group of species. By identifying the shortest absent peptide sequences from the NCBI databases, we screened several potential anti-cancer peptides. In order to improve cell penetration and solubility we added short poly arginine tails (5Rs), and initially solubilized the peptides in1M trehalose. The results for one of the absent sequences 9R (RRRRRNWMWC), and its scrambled version 9S1R (RRRRRWCMNW) are reported here. We refer to these peptides derived from nullomers as PolyArgNulloPs. A control …

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A Node Based Volume Modeling And Rendering Toolkit For Python, Robert Kern Dec 2012

A Node Based Volume Modeling And Rendering Toolkit For Python, Robert Kern

All Theses

This thesis covers the implementation and use of a node based volume modeling and ren- dering toolkit for python. The first part of the thesis covers the code structure of the toolkit, the implementation of the nodes, and how they are evaluated. Operator graphs are built from nodes to create and shape volumes. During volume rendering these graphs are evaluated for the density and color values. The second part of the thesis covers how the toolkit was used to create and render volumetric effects by emulating an effect seen in a movie. The animation of the effect, the use of …

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Creche Herald Vol. 16, No. 4, Rita B. Bocher Dec 2012

Creche Herald Vol. 16, No. 4, Rita B. Bocher

Creche Herald

The Winter 2012-13 publication features nativity sets and personal reflections from members in the organization; information about nativities and nativity exhibits; and information about the Friends of the Creche annual meeting.

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Decf2012, Robert Kelly Dec 2012

Decf2012, Robert Kelly

Robert Kelly Manuscripts

From December 2012 Robert Kelly Archives

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Dece2012, Robert Kelly Dec 2012

Dece2012, Robert Kelly

Robert Kelly Manuscripts

From December 2012 Robert Kelly Archives

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Evans's 'The Turducken' And Chekhov's 'The Seagull', Brian R. Johnson Dec 2012

Evans's 'The Turducken' And Chekhov's 'The Seagull', Brian R. Johnson

Russian Faculty Works

In his article "Evans's The Turducken and Chekhov's The Seagull" Brian R. Johnson approaches The Turducken as a travesty of The Seagull, examining six iconic scenes from The Seagull, in order to explore the satirical effect of the altered scenes. In December of 2008, Bedlam Theatre of Minneapolis presented The Turducken, "a holiday dinner theater spectacular inspired by Anton Chekhov's The Seagull." Playwright Josef Evans takes Chekhov's 1895 work and turns the classic piece into a musical and farcical satire. The plot of The Turducken follows the plot of The Seagull, and some scenes in The Turducken are recognizable as …

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Fak Is A Critical Regulator Of Neuroblastoma Liver Metastasis, Sora Lee, Jingbo Qiao, Pritha Paul, Kathleen L. O'Connor, B. Mark Evers, Dai H. Chung Dec 2012

Fak Is A Critical Regulator Of Neuroblastoma Liver Metastasis, Sora Lee, Jingbo Qiao, Pritha Paul, Kathleen L. O'Connor, B. Mark Evers, Dai H. Chung

Surgery Faculty Publications

Neuroblastomas express increased levels of gastrin-releasing peptide receptor (GRP-R). However, the exact molecular mechanisms involved in GRP-R-mediated cell signaling in neuroblastoma growth and metastasis are unknown. Here, we report that focal adhesion kinase (FAK), as a critical downstream target of GRP-R, is an important regulator of neuroblastoma tumorigenicity. We found that FAK expression correlates with GRP-R expression in human neuroblastoma sections and cell lines. GRP-R overexpression in SK-N-SH cells increased FAK, integrin α3 and β1 expressions and cell migration. These cells demonstrated flatter cell morphology with broad lamellae, in which intense FAK expression was localized to the leading edges of …

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Can Law And Literature Be Practical? The Crucible And The Federal Rules Of Evidence, Martin H. Pritikin Dec 2012

Can Law And Literature Be Practical? The Crucible And The Federal Rules Of Evidence, Martin H. Pritikin

West Virginia Law Review

Counter-intuitively, one of the best ways to learn the practice-oriented topic of evidence may be by studying a work of fiction-specifically, Arthur Miller's The Crucible, which dramatizes the seventeenth-century Salem witch trials. The play puts the reader in the position of legal advocate, and invites strategic analysis of evidentiary issues. A close analysis of the dialogue presents an opportunity to explore both the doctrinal nuances of and policy considerations underlying the most important topics covered by the Federal Rules of Evidence, including the mode and order of interrogation, relevance, character evidence and impeachment, opinion testimony, and hearsay.

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Introduction, Ernest Caldwell, Terry Nardin Dec 2012

Introduction, Ernest Caldwell, Terry Nardin

Chicago-Kent Law Review

No abstract provided.

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Journeys To Others And Lessons Of Self: Carlos Castaneda In Camposcape, Ageeth Sluis Dec 2012

Journeys To Others And Lessons Of Self: Carlos Castaneda In Camposcape, Ageeth Sluis

Scholarship and Professional Work - LAS

Drawing on Michel Foucault’s concept of heterotopia, this article examines the importance of place and gender within constructions of race politics in Carlos Castaneda’s series on shamanism. Championing a “separate reality” predicated on an indigenous worldview, Castaneda’s lessons invited transnational middle-class youth to "journey" alongside him to camposcape—an anachronistic and idealized countryside—as a means to escape the bourgeois values of their homelands and find spiritual fulfillment in a timeless and "authentic" Mexico. Castaneda’s work proposed new viable spaces of difference in Mexico, yet inscribed these spaces with a masculinist discourse that served to neutralize the gender trouble within the counterculture …

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