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2012

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Articles 5101 - 5130 of 19169

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Conditional Over-Expression Of Pitx1 Causes Skeletal Muscle Dystrophy In Mice, Sachchida Nand Pandey, Jennifer Cabotage, Rongye Shi, Manjusha Dixit, Margaret L. Sutherland, Jian Liu, Stephanie Muger, Scott Q. Harper, Kanneboyina Nagaraju, Yi-Wen Chen Jul 2012

Conditional Over-Expression Of Pitx1 Causes Skeletal Muscle Dystrophy In Mice, Sachchida Nand Pandey, Jennifer Cabotage, Rongye Shi, Manjusha Dixit, Margaret L. Sutherland, Jian Liu, Stephanie Muger, Scott Q. Harper, Kanneboyina Nagaraju, Yi-Wen Chen

Genomics and Precision Medicine Faculty Publications

Paired-like homeodomain transcription factor 1 (PITX1) was specifically up-regulated in patients with facioscapulohumeral muscular dystrophy (FSHD) by comparing the genome-wide mRNA expression profiles of 12 neuromuscular disorders. In addition, it is the only known direct transcriptional target of the double homeobox protein 4 (DUX4) of which aberrant expression has been shown to be the cause of FSHD. To test the hypothesis that up-regulation of PITX1 contributes to the skeletal muscle atrophy seen in patients with FSHD, we generated a tet-repressible muscle-specific Pitx1 transgenic mouse model in which expression of PITX1 in skeletal muscle can be controlled by oral administration of …

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Perceptual Modelling Of Environmental Indicators To Assess Land Uses Impacts On Water Quality, Nathalie Lalande, Flavie Cernesson, Marie-George Tournoud Jul 2012

Perceptual Modelling Of Environmental Indicators To Assess Land Uses Impacts On Water Quality, Nathalie Lalande, Flavie Cernesson, Marie-George Tournoud

International Congress on Environmental Modelling and Software

The stream functioning is closely influenced by land uses, along thestream itself and throughout the catchment. Land uses can be seen as both theexpression of the natural environment and the result of increasing human activities.Land uses generate various (in kind and intensity) pressures (positive or negative)that alter river water quality at different scales of time and space. The objective ofthis research is to conceptualize and quantify the interactions between river waterquality and land use through spatial modelling. Our methodology is based on (i) thedesign of a system of indicators using the DPSIR framework and (ii) thedevelopment of the relevant environmental …

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Museu.M. News, No. 34, University Of Montana--Missoula. Philip L. Wright Zoological Museum Jul 2012

Museu.M. News, No. 34, University Of Montana--Missoula. Philip L. Wright Zoological Museum

Philip L. Wright Zoological Museum (UMZM) Newsletters

Recent Accessions -- Museum Art Show -- Follow the Museum's Blog! -- The Museum in the News -- Friends of Museum Dues are DUE!

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Crown Of The Continent Magazine - Summer 2012, University Of Montana, Missoula Jul 2012

Crown Of The Continent Magazine - Summer 2012, University Of Montana, Missoula

Crown of the Continent and the Greater Yellowstone Magazine

Table of Contents: Introduction -- The Crown of the Continent - Floods of June 1964 and a Pulitzer Prize -- Piegans in Paradise -- Photography Spotlight -- Crown of the Continent Weather Extremes and Records -- The Scapegoat Wilderness Celebrates 40 Years

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2012/2013 University Of The Pacific [Stockton] Graduate Catalog, University Of The Pacific Jul 2012

2012/2013 University Of The Pacific [Stockton] Graduate Catalog, University Of The Pacific

Catalogue, Bulletin, Catalog

No abstract provided.

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Ict, Integral Models And New Methods Support Farmer´S And Forester´S Integration Into Environmental Caretaking And Risk-Management, H Mayer Di Walte Jul 2012

Ict, Integral Models And New Methods Support Farmer´S And Forester´S Integration Into Environmental Caretaking And Risk-Management, H Mayer Di Walte

International Congress on Environmental Modelling and Software

Farmers and foresters – in total worldwide more than 2 billion people - manage large parts of most of the countries, in some 90% or more. Rich, risk-exposure countries with beautiful nature like Austria or Switzerland due to mountains did a lot of excellent environmental caretaking because of intensive tourism and reduced with the help of government existing risks, supported by legislation, avalanche-, torrent- or river- departments, land consolidation units, Chambers of Agriculture, Ministerial departments etc. and were supported by farmers with a general concept: Managing a farm or forest correctly, manages also the environment well. EC´s GAP (Good Agricultural …

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Developing And Integrating A Simulation Model Of Water Resources Supply And Demand Within An On-Going Governance Building Process : A Case Study In Thau Catchment, South Of France., Geraldine Abrami, Audrey Richard-Ferroudji, Sylvain Barone, Olivier Barreteau, Camille Tessier Jul 2012

Developing And Integrating A Simulation Model Of Water Resources Supply And Demand Within An On-Going Governance Building Process : A Case Study In Thau Catchment, South Of France., Geraldine Abrami, Audrey Richard-Ferroudji, Sylvain Barone, Olivier Barreteau, Camille Tessier

International Congress on Environmental Modelling and Software

A companion modeling process about water resources supply and demand at the scale of a catchment in partnership with the catchment management institution and with intermediary level stakeholders of the different sectors of water use, production and distribution in the territory is being held in the Thau catchment, near Montpellier in South of France. This companion modeling process has been shaped by both a scientific questioning about interactions between land and water dynamics and governance within a catchment and the history of collaborations between the research team and the case study partners. It was initiated by the catchment management institution’s …

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Modelling Trade-Offs Between Ecosystem Services And Agricultural Production In Western Australia, Marit E. Kragt, Michael J. Robertson Jul 2012

Modelling Trade-Offs Between Ecosystem Services And Agricultural Production In Western Australia, Marit E. Kragt, Michael J. Robertson

International Congress on Environmental Modelling and Software

The concept of ecosystem services (ES) is widely used to highlight theinterdependencies between agricultural and environmental systems. Many ESprovide direct production benefits to agriculture-even those that are not directlyproducing agricultural commodities, such as pollination, water regulation, and soilretention. Farm management practices may produce ES or ‘disservices’, such asnutrient pollution or greenhouse gas emissions. Few studies have attempted toquantify the potential of agriculture to produce multiple ES, and to estimate thepossibilities for joint production of marketed and non-marketed ES. A quantificationof the trade-offs between ES provision and production of farm commodities canhelp to better target agricultural policies.We use a well-established biophysical …

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Phosphorus Use And Management Strategies: Exploring Scenarios Of Smallholder’S Soil Fertility, Food Production And Livelihood With A Multi-Agent System Model, Quang Bao Le, Roland W. Scholz, Roman Seidl, Quyet Manh Vu, Tien Minh Tran Jul 2012

Phosphorus Use And Management Strategies: Exploring Scenarios Of Smallholder’S Soil Fertility, Food Production And Livelihood With A Multi-Agent System Model, Quang Bao Le, Roland W. Scholz, Roman Seidl, Quyet Manh Vu, Tien Minh Tran

International Congress on Environmental Modelling and Software

Phosphorus (P) is a key nutrient for food production. However, excess P use, e.g. in form of inorganic fertilizer application, can lead to environmental pollution, biodiversity losses and low profitability. Continuous cultivation with underuse of P fertilizer results in low food productivity and soil degradation due to soil nutrient mining or soil erosion. The concern is most serious for smallholder farmers in developing countries whose food production and livelihood is tied directly to their access to and efficient use of P as key nutrient for plant growth. This paper introduces a multi-agent system modeling framework for assessing long-term impacts of …

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Participatory Land Use Modeling With Bayesian Networks: A Focus On Subjective Validation, Enrico Celio, Sibyl H. Brunner, Adrienne Grêt-Regamey Jul 2012

Participatory Land Use Modeling With Bayesian Networks: A Focus On Subjective Validation, Enrico Celio, Sibyl H. Brunner, Adrienne Grêt-Regamey

International Congress on Environmental Modelling and Software

Taking into account land use models in spatial planning processes would be a valuable support for facilitating the development and the acceptance of innovative land use management strategies. But, the utilization of such models in spatial planning processes is rarely done. One condition for implementation is trust and credibility in the model, which can be increased through validation. We argue that subjective validation can be a major contribution to efforts advancing the implementation of models. The presented land use model applies Bayesian networks (BN) and incorporates secondary data as well as local actors’ characteristics. Stakeholders from the study area and …

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End Matter, Religious Educator Jul 2012

End Matter, Religious Educator

Religious Educator: Perspectives on the Restored Gospel

No abstract provided.

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Family Affairs Newsletter 2012-07-01, Zack Paakkonen Jul 2012

Family Affairs Newsletter 2012-07-01, Zack Paakkonen

Family Affairs newsletter (2004-2016)

FAMILY AFFAIRS was a free, twice-a-month, social activities newsletter for the GLBTQI (gay/lesbian/bisexual/trans/queer/intersex) community, sent out around the 1st and 15th of each month. It covered the State of Maine only. The list was begun and maintained for many years by Jean Vermette in Bangor, and later operated by Zack Paakkonen of Portland. Over the years it evolved from a social activities newsletter into a business directory, classified ad service, and community bulletin board.

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Germline Transgenesis And Insertional Mutagenesis In Schistosoma Mansoni Mediated By Murine Leukemia Virus, Gabriel Rinaldi, Sabine E. Eckert, Isheng J. Tsai, Suttas Suttiprapa, Kristine J. Kines, Jose F. Tort, Victoria H. Mann, Daniel J. Turner, Matthew Berriman, Paul J. Brindley Jul 2012

Germline Transgenesis And Insertional Mutagenesis In Schistosoma Mansoni Mediated By Murine Leukemia Virus, Gabriel Rinaldi, Sabine E. Eckert, Isheng J. Tsai, Suttas Suttiprapa, Kristine J. Kines, Jose F. Tort, Victoria H. Mann, Daniel J. Turner, Matthew Berriman, Paul J. Brindley

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium. To develop transgenesis as a functional approach for these pathogens, we previously demonstrated that pseudotyped murine leukemia virus (MLV) can transduce schistosomes leading to chromosomal integration of reporter transgenes and short hairpin RNA cassettes. Here we investigated vertical transmission of transgenes through the developmental cycle of S. mansoni after introducing transgenes into eggs. Although MLV infection of schistosome eggs from mouse livers was efficient in terms of snail infectivity, >10-fold higher transgene copy …

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Macalester Today Summer 2012, Macalester College Jul 2012

Macalester Today Summer 2012, Macalester College

Macalester Today

No abstract provided.

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Attorneys And Entrepreneurs: Creating Value For Small Business Startups, Laurie A. Lucas, Griffin T. Pivateau Jul 2012

Attorneys And Entrepreneurs: Creating Value For Small Business Startups, Laurie A. Lucas, Griffin T. Pivateau

Texas Wesleyan Law Review

The attorney who understands an entrepreneurial organization at different stages of growth may be better able to anticipate the problems the organization may face over the long term. Legal issues for small businesses, for example, generally include the appropriate choice of business structure, protection and management of intellectual property, and effective management of human resources, which have all been affected by the technologies that are reshaping American society and its workforce. The attorney who understands the stages of smallbusiness growth, even in a general sense, may have a more effective lens" for providing legal assistance to a small business. This …

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Pornography And Rape Myths In Paranormal Romance Novels, Lesley Erin Dennis Jul 2012

Pornography And Rape Myths In Paranormal Romance Novels, Lesley Erin Dennis

Morehead State Theses and Dissertations

A thesis presented to the faculty of the Caudill College of Humanities, Arts and Social Sciences at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Arts by Lesley Erin Dennis in July of 2012.

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Jax Archives Complete Inventory List, The Jackson Laborarory Archives Jul 2012

Jax Archives Complete Inventory List, The Jackson Laborarory Archives

Complete Inventory

No abstract provided.

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Condition And Brightness Of Structural Blue-Green: Motmot Tail-Racket Brightness Is Related To Speed Of Feather Growth In Males, But Not In Females, Troy G. Murphy, Tiffany T. Pham Jul 2012

Condition And Brightness Of Structural Blue-Green: Motmot Tail-Racket Brightness Is Related To Speed Of Feather Growth In Males, But Not In Females, Troy G. Murphy, Tiffany T. Pham

Biology Faculty Research

Coloration plays an important role in sexual and social communication, and in many avian species both males and females maintain elaborate colours. Recent research has provided strong support for the hypothesis that elaborate female traits can be maintained by sexual or social selection; however, most research on female ornamentation has focused on pigment-based colours, and less is known about how structural colours are maintained. Both sexes of the turquoise-browed motmot (Eumomota superciliosa) have a blue-green racket-tipped tail, and it remains unknown if tail coloration serves as a sexual or social signal in one or both sexes. Here, we …

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Julk2012, Robert Kelly Jul 2012

Julk2012, Robert Kelly

Robert Kelly Manuscripts

From July 2012 Robert Kelly Archives

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Southern Register. 2012.3 (Summer 2012), University Of Mississippi. Center For The Study Of Southern Culture Jul 2012

Southern Register. 2012.3 (Summer 2012), University Of Mississippi. Center For The Study Of Southern Culture

Southern Register

No abstract provided.

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The Proteomics Of Lipid Droplets: Structure, Dynamics, And Functions Of The Organelle Conserved From Bacteria To Humans., Li Yang, Yunfeng Ding, Yong Chen, Shuyan Zhang, Chaoxing Huo, Yang Wang, Jinhai Yu, Peng Zhang, Huimin Na, Huina Zhang, Yanbin Ma, Pingsheng Liu Jul 2012

The Proteomics Of Lipid Droplets: Structure, Dynamics, And Functions Of The Organelle Conserved From Bacteria To Humans., Li Yang, Yunfeng Ding, Yong Chen, Shuyan Zhang, Chaoxing Huo, Yang Wang, Jinhai Yu, Peng Zhang, Huimin Na, Huina Zhang, Yanbin Ma, Pingsheng Liu

College of Science & Mathematics Departmental Research

Lipid droplets are cellular organelles that consists of a neutral lipid core covered by a monolayer of phospholipids and many proteins. They are thought to function in the storage, transport, and metabolism of lipids, in signaling, and as a specialized microenvironment for metabolism in most types of cells from prokaryotic to eukaryotic organisms. Lipid droplets have received a lot of attention in the last 10 years as they are linked to the progression of many metabolic diseases and hold great potential for the development of neutral lipid-derived products, such as biofuels, food supplements, hormones, and medicines. Proteomic analysis of lipid …

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Existentialism, Phenomenology, And Education, James Magrini Jul 2012

Existentialism, Phenomenology, And Education, James Magrini

Philosophy Scholarship

No abstract provided.

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The Influence Of Carl Jung’S Archetype Of The Shadow On Early 20th Century Literature, Dana Brook Thurmond Jul 2012

The Influence Of Carl Jung’S Archetype Of The Shadow On Early 20th Century Literature, Dana Brook Thurmond

Master of Liberal Studies Theses

This thesis seeks to establish a direct relationship between the archetypes of Carl Jung, primarily the Shadow, and early 20th century literature. The Shadow is best described as our darker selves, the primitive unconsciousness that subtly invades our waking moments. Modern society has sought to suppress this Shadow, which has led to repression and potential psychoses. Many authors of the late Victorian and early modern period address the problems with societal expectations in their works. This thesis will explore the writing of Henry James, Bram Stoker, Robert Louis Stevenson, and T. S. Eliot to see how they deal with Jung's …

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The Human Phosphotyrosine Signaling Network: Evolution And Hotspots Of Hijacking In Cancer., Lei Li, Chabane Tibiche, Cong Fu, Tomonori Kaneko, Michael F. Moran, Martin Schiller, Shawn Shun-Cheng Li, Edwin Wang Jul 2012

The Human Phosphotyrosine Signaling Network: Evolution And Hotspots Of Hijacking In Cancer., Lei Li, Chabane Tibiche, Cong Fu, Tomonori Kaneko, Michael F. Moran, Martin Schiller, Shawn Shun-Cheng Li, Edwin Wang

Life Sciences Faculty Research

Phosphotyrosine (pTyr) signaling, which plays a central role in cell-cell and cell-environment interactions, has been considered to be an evolutionary innovation in multicellular metazoans. However, neither the emergence nor the evolution of the human pTyr signaling system is currently understood. Tyrosine kinase (TK) circuits, each of which consists of a TK writer, a kinase substrate, and a related reader, such as Src homology (SH) 2 domains and pTyr-binding (PTB) domains, comprise the core machinery of the pTyr signaling network. In this study, we analyzed the evolutionary trajectories of 583 literature-derived and 50,000 computationally predicted human TK circuits in 19 representative …

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Violencia Y Apocalipsis En El Día Señalado De Manuel Mejía Vallejo, Virginia Capote Diaz Jul 2012

Violencia Y Apocalipsis En El Día Señalado De Manuel Mejía Vallejo, Virginia Capote Diaz

Hipertexto

No abstract provided.

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El Viejo Puente, El Río Y El Mercado: Avatares De La Subjetivación En "Gregorio" Del Grupo Chaski, Pablo Salinas Jul 2012

El Viejo Puente, El Río Y El Mercado: Avatares De La Subjetivación En "Gregorio" Del Grupo Chaski, Pablo Salinas

Hipertexto

No abstract provided.

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Terrestrial Ecosystem Carbon Fluxes Predicted From Modis Satellite Data And Large-Scale Disturbance Modeling, Christopher Potter, Steven Klooster, Vanessa Genovese, Cyrus Hiatt, Shyam Boriah, Vipin Kumar, Varun Mithal, Ashish Garg Jul 2012

Terrestrial Ecosystem Carbon Fluxes Predicted From Modis Satellite Data And Large-Scale Disturbance Modeling, Christopher Potter, Steven Klooster, Vanessa Genovese, Cyrus Hiatt, Shyam Boriah, Vipin Kumar, Varun Mithal, Ashish Garg

School of Natural Sciences Faculty Publications and Presentations

The CASA (Carnegie-Ames-Stanford) ecosystem model based on satellite greenness observations has been used to estimate monthly carbon fluxes in terrestrial ecosystems from 2000 to 2009. The CASA model was driven by NASA Moderate Resolution Imaging Spectroradiometer (MODIS) vegetation cover properties and large-scale (1-km resolution) disturbance events detected in biweekly time series data. This modeling framework has been implemented to estimate historical as well as current monthly patterns in plant carbon fixation, living biomass increments, and long-term decay of woody (slash) pools before, during, and after land cover disturbance events. Results showed that CASA model predictions closely followed the seasonal timing …

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The Frequency Of Ch /ʧ/ In Contemporary Mexican Highland Spanish, Daniel Nappo Jul 2012

The Frequency Of Ch /ʧ/ In Contemporary Mexican Highland Spanish, Daniel Nappo

Hipertexto

That particular sounds are characteristic of different languages is widely understood. For example, studies of Amerindian languages of the Amazon basin have discovered sounds as unique as a ―voiced, lateralized apical-alveolar/sublaminal-labial double flap with egressive lung air‖ [L,], exhibited only in Pirahã, an isolated language spoken by approximately one hundred people (Everett 92). English has an apparent proclivity for the phoneme /ʃ /, which, as Baugh and Cable point out, may be produced by twelve different spellings (14). This paper argues that the phoneme /ʧ /, represented exclusively in Spanish by the digraph ch, may be viewed as one of …

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Moulinet: An Action Quarterly, Volume 13, Issue 3, Moulinet Staff Jul 2012

Moulinet: An Action Quarterly, Volume 13, Issue 3, Moulinet Staff

Moulinet: An Action Quarterly

No abstract provided.

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Does Terrain Slope Really Dominate Goal Searching?, Daniele Nardi Jul 2012

Does Terrain Slope Really Dominate Goal Searching?, Daniele Nardi

Faculty Research and Creative Activity

If you can locate a target by using one reliable source of information, why would you use an unreliable one? A similar question has been faced in a recent study on homing pigeons, in which, despite the presence of better predictors of the goal location, the slope of the floor in an arena dominated the searching process. This piece of evidence seems to contradict straightforward accounts of associative learning, according to which behavior should be controlled by the stimulus that best predicts the reward, and has fueled interest toward one question that, to date, has received scarce attention in the …

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