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Ankle Injuries In The Growing Skeleton. A Review Of The Recent Literature, Marwan M. Zamzami

Saudi Medical Journal

Ankle injuries arise with significant frequency in the pediatric population, although diagnosis is rarely straightforward. Contact sports, such as football are widely practiced in Saudi athletes, little is carried out to educate them of measures regarding playing conditions and prophylactic steps like foot wear, warming up, and similarly. The usual potential complications associated with trauma to mature skeleton, as well as immature selection includes post-traumatic arthritis, stiffness, reflex sympathetic dystrophy, as well as those seen with physeal damage including leg length discrepancy, angular deformities, or a combination. Knowledge of these injuries, as well as the differences between children and adult …

Protective Efficacy Of Immunoglobulins Y Prepared Against Cerastes Cerastes Snake Venom In The Kingdom Of Saudi Arabia, Ihab M. Moussa, Ashgan M. Hessan, Abdulaziz M. Aleisa, Abdullah A. Al-Arfaj, Mounier M. Salem-Bekhit, Salim A. Alrejai

Saudi Medical Journal

OBJECTIVE: To prepare and evaluate the protective efficacy of immunoglobulin Y (IgY) prepared against local Saudi Cerastes cerastes snake venom. METHODS: The study was conducted between October 2009 and October 2011 at the Center of Excellence in Biotechnology Research, King Saud University, Riyadh, Kingdom of Saudi Arabia. The study designed as follow; 4 groups of 8 chickens were immunized intramuscularly with Cerastes cerastes snake venoms mixed with Freund9s complete adjuvant. Three weeks later, the injections were repeated with the venoms with incomplete Freund9s adjuvant. Three boosters were given with the venoms at 3 weeks intervals. The IgY was extracted by …

Management Of Invasive Coqui Frog Populations In Hawaii, William C. Pitt, Karen H. Beard, Rogelio E. Doratt

United States Department of Agriculture Wildlife Services: Staff Publications

During the last 25 years, two species of Eleutherodactylus frogs, coqui and greenhouse frogs, have become established in Hawaii and other Pacific Islands. Coqui frogs, Eleutherodactylus coqui, were introduced to Hawaii prior to 1988 via the horticultural trade (Kraus & Campbell 2002). Since their introduction, the number and size of coqui frog infestations have rapidly increased and frogs have spread throughout the four main Hawaiian Islands with the largest infestation on the island of Hawaii. Coqui frogs are small (<65 mm in length) nocturnal tree frogs that are endemic to the island Puerto Rico (Beard et al. 2008). They are completely terrestrial and do not need open water for development because the frogs …

Sheep And Wool In Nineteenth-Century Falmouth, Ma: Examining The Collapse Of A Cape Cod Industry, Leo Patrick Ledwell

Graduate Masters Theses

This thesis examines the collapse of the sheep industry in Falmouth, Massachusetts in the 1830s. The documentary evidence for the collapse is examined through both the lens of microhistory and that of the traditional model for the collapse, one set forth by the American Geographical Society. The traditional model suggests that the importation of cheap agricultural goods from western states like Ohio caused the collapse of commercial farming in New England. An examination of the local evidence, however, suggests that the real reasons for the collapse of the sheep industry in Falmouth are much more complex, leaving open the possibility …

Zifazah: A Scientific Visualization Language For Tensor Field Visualizations, Haipeng Cai

Master's Theses

This thesis presents the design and prototype implementation of a scientific visualization language called Zifazah for composing and exploring 3D visualizations of diffusion tensor magnetic resonance imaging (DT-MRI or DTI) data. Unlike existing tools allowing flexible customization of data visualizations that are programmer-oriented, Zifazah focuses on domain scientists as end users in order to enable them to freely compose visualizations of their scientific data set. Verbal descriptions of end users about how they would build and explore DTI visualizations are analyzed to collect syntax, semantics, and control structures of the language. Zifazah makes use of the initial set of lexical …

Improved Detection Methods For Selected Vibrio Species In The Marine Aquatic Environment, Kimberly Jordan Griffitt

Master's Theses

Vibrio vulnificus, Vibrio cholerae, and Vibrio parahaemolyticus are the three most commonly encountered human pathogens in the Vibrio genus. They are frequent agents of foodborne illness contracted from seafood. The work presented here focuses on three aspects of detection of these bacteria. First is a novel agar formulation designed to isolate and directly enumerate V. vulnificus from oyster tissue by using x-gal, a chromogenic analog to lactose, as a carbon source and agent of differential morphological colony growth. Second is a field study on the relative abundance of the three main pathogenic Vibrios following the opening of the …

Photo-Poetics: Photographic Narratives In The New Journalism, John David Hosemann Jr.

Master's Theses

Americans today have come to remember the unrest of the 1960s through the many shocking photographic images that emerged during that time. Images of assassinations, war, murders, and social upheaval have come to characterize this decade as particularly (perhaps perversely) photogenic. Further, these images have revealed the photographic medium as uniquely suited for confirming a violent reality that, at the time, seemed incomprehensible to an increasingly disillusioned public. In this discussion I seek to develop an understanding of photography as a theoretical process that can illuminate how we represent violent subject matter. In doing so, I apply these concepts to …

Panic Behind The Mask: The Spanish Influenza Epidemic Of 1918 In New Orleans, Sarah Theresa Savage

Master's Theses

As part of the most devastating influenza pandemic in modern history, the Spanish Influenza epidemic in New Orleans left the city emotionally and physically crippled as residents struggled to resume daily life after thousands succumbed to a bloody cough and painful death in October 1918. When New Orleans public health officials reacted to the explosion of Spanish Influenza cases on October 10, 1918, the virus had already traveled throughout the population. Unlike previous influenza outbreaks, the 1918 epidemic killed primarily young healthy adults, the backbones of the working force and families. In an attempt to quarantine the ill from the …

Is Local Food In Your Future?: An Analysis Of The Viability Of The Local Food Movement, Jennifer A. Sliney

Pell Scholars and Senior Theses

The Local Food Movement has arisen in recent decades as a proposed solution to problems in the current food distribution system. Proponents of the movement look to solve problems such as unsustainable farming practices, greenhouse gas emissions, and unhealthy communities. Skeptics raise questions as to whether local food is truly capable of accomplishing any of those. The author proposes that as a solution, aspects of the Local Food Movement such as urban agriculture and attempts at community development should be taken more seriously in order to create a better future for the land and people alike.

Darkness In The City Of Light: The Great Roundup Of 1942 & France’S Role In The Shoah., Benjamin T.C. Mead

Pell Scholars and Senior Theses

This thesis explores the incident of the Vel d'Hiv Roundup in Paris in July of 1942. It was the largest roundup of Jews in France during WWII, and remains a topic that is still very taboo, but due to books like "Sarah's Key" and rising interest, other nation's roles in the Holocaust are being explored. The author drawing upon three focuses of study-- majors in History, Religious & Theological Studies, and a French minor-- attempts to show how the Holocaust impacted a nation who's national motto is "Liberty, Equality, Brotherhood."

African Slavery In Colonial Veracruz: The Factors That Aided Its Creation And Expansion, Veronica Nohemi Duran

Theses and Dissertations - UTB/UTPA

The focal point of this study is to prove that it was the simultaneous presence of five factors during the 16th and 17th centuries that allowed African enslavement in Veracruz to expand. I built upon previous works and authors to support my claim that it was the decline in native population, economic profits, religious apathy on the subject, social acceptance and government support that pushed for the systems creation and expansion. By discussing each of these factors in a chapter of their own, I concluded that in an almost cause and effect manner these factors are responsible for the expansion …

Comparisons Of Emotional Reactivity In Two Variations Of Schedules Of Reinforcement, Mayra A. Aguillon

Theses and Dissertations - UTB/UTPA

Operant conditioning is a type of learning in which the frequency of behavior is affected by its consequences (Powell, Symbaluk & Honey 2009).The main focus of the study was to compare two different schedules of reinforcement: gradual group versus the abrupt group (FI-20 sec).Both groups were used to observe emotional reactivity in 8 Sprague Dawley female rats from the Behavioral Neuroscience lab at UTPA. The hypothesis presented was that animals will reveal less emotional reactivity in the gradual than in the abrupt. According to Skinner, behavior is affected more by the consequence that is followed. Results suggested that the abrupt …

A History Of Labor Degradation On The Border, Hidalgo County, Texas, 1920-1970s, Edward David Avila

Theses and Dissertations - UTB/UTPA

Between 1920 and 1970 laborers in Hidalgo County were degraded and ranked among the lowest paid workers in the nation. Colonizers including land developers seeking to exploit the commercial agriculture potential of the Rio Grande Valley divided the working poor along race, gender, and class lines. Such labor strategy allowed Anglo Americans and in some cases elite Mexicans to subjugate working class Mexicans and Mexican Americans to substandard wages and miserable working conditions. This thesis argues the origin of the degradation of the working poor by analyzing wages, work conditions, race relations, and gendered dimensions of labor in the region. …

The Geographies Of Religious Conversion, Orlando Woods

Research Collection School of Social Sciences

The paper reviews the corpus of research that attempts to explain the process of religious conversion, and explores the ways in which geographers can add new perspectives to the discourse. It argues that religious conversion is a phenomenon that goes beyond the reorientation of individual belief, and is instead a process of change that involves the (re)definition of self and other. Five conceptual frames are proposed - (1) conversion of space; (2) spaces of conversion; (3) spaces of negotiation; (4) the (im)mobile convert; and (5) the (dis)embodied convert - which are used to help define the geographies of religious conversion.

A Narrative Life Story Of Activist Phyllis Lyon And Her Reflections On A Life With Del Martin, Dianna Lee Johnson

Masters Theses

Phyllis Lyon met the love of her life in 1953. Her name was Del Martin. When they fell in love, homosexuality was an illness that needed to be cured, a sin to be confessed and an illegal act that should be punished. Del Martin and Phyllis Lyon are legendary in the lesbian community for originating the Daughters of Bilitis--an underground lesbian social club in San Francisco formed in the 1950s. They spent the next 55 years together confronting society and policy about the inequity of gays, lesbians, and women. In each of these social movements, however, they were the minority …

The 9/11 Cancer Conundrum: The Law, Policy, & Politics Of The Zadroga Act, Kimberly Gordy

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

The Modern Sex Doll-Owner: A Descriptive Analysis, Sarah Hatheway Valverde

Master's Theses

Over the last fifteen years, the sex doll industry has grown from producing inexpensive novelty items to creating a multimillion-dollar global industry featuring high- quality, realistic love dolls. These dolls are designed and advertised for sexual stimulation, companionship, artistic representations of human fantasy, and other creative pursuits, such as photography. Made of flesh-like silicone, modern sex dolls sell from $3,500-$10,000.

The use of human simulacra for sexual stimulation is an enduring practice. However, the psychological community has said little on the subject. Early sexologists briefly reference Agalmatophilia or Statuphilia, a rare sexual attachment to statues. Today, the sex doll …

Nutritional Content Of Rhinoceros Auklet (Cerorhinca Monocerata) Bill Loads, Dustin Taylor, Ron Heintz

STAR Program Research Presentations

Nutritional Content of Rhinoceros Auklet Bill Loads

Dustin E Taylor

Abstract

An adult Rhinoceros Auklet (Cerorhinca monocerata) can only catch and carry a limited amount of prey to their nestlings after a foraging trip. The auklets therefore must maximize their efficiency by bringing back the most proportionally nutritious prey items to their nestlings. The prey carried back to the nesting sites (known as a ‘bill load’) can contain whole fish, as well as parts, most commonly fish heads. This study is aimed to determine whether returning with just heads to the nestlings was proportionally more nutritious than bringing …

Effects Of Pristane On Growth Of Pink Salmon (Oncorhynchus Gorbuscha), Brielle D. Kemis, Bonita Nelson

STAR Program Research Presentations

Pristane is a naturally occurring hydrocarbon that is generated by copepods in marine ecosystems. Organisms that eat copepods do not readily metabolize pristane, which causes it to accumulate throughout the marine food web. Understanding how pristane affects marine fish is essential because pristane is often used as a bioindicator in lab studies and may be influencing results in those studies. Also, this hydrocarbon may significantly reduce growth of marine fish in the wild. A previous study indicated that pristane is an appetite suppressant and growth retardant in fish. However, the study implemented a feeding regime with unnaturally high levels of …

Il-22 Signaling Contributes To West Nile Encephalitis Pathogenesis, Fengwei Bai, Penghua Wang, Lauren A. Zenewicz, Jianfeng Dai, David Gate, Gong Cheng, Long Yang, Feng Qian, Xiaoling Yuan, Ruth R. Montgomery, Richard A. Flavell, Terrence Town, Erol Fikrig

Faculty Publications

The Th17 cytokine, IL-22, regulates host immune responses to extracellular pathogens. Whether IL-22 plays a role in viral infection, however, is poorly understood. We report here that Il22^-/- mice were more resistant to lethal West Nile virus (WNV) encephalitis, but had similar viral loads in the periphery compared to wild type (WT) mice. Viral loads, leukocyte infiltrates, proinflammatory cytokines and apoptotic cells in the central nervous system (CNS) of Il22^-/- mice were also strikingly reduced. Further examination showed that Cxcr2, a chemokine receptor that plays a non-redundant role in mediating neutrophil migration, was significantly reduced in Il22^{-/- …}

Perceptions And Satisfaction Of Healthy Food Choices Among College-Aged Females In A Self-Serve Dining Facility Setting, Kristin Timken

Theses

AN ABSTRACT OF THE THESIS OF Kristin Timken, for the Master of Science degree in Food & Nutrition, presented on November 21, 2011, at Southern Illinois University Carbondale. TITLE: PERCEPTIONS & SATISFACTION OF HEALTHY FOOD CHOICES AMONG COLLEGE-AGED FEMALES IN A SELF-SERVE DINING FACILITY SETTING MAJOR PROFESSOR: Dr. Sara Long Roth Objective: The purpose of this study was to measure perceptions of healthy food choices and satisfaction of menu choices among members of a sorority house. Design: Three surveys were used in this experiment, two pre-tests and one post-test. Subjects and Setting: The study consisted of a self-selected sample of …

Synthetic Biology: Does Re-Writing Nature Require Re-Writing Regulation?, Jordan Paradise, Ethan Fitzpatrick

Penn State Law Review (2003 - Present)

No abstract provided.

Characterization And Treatment Of A Novel Mouse Model Of Tsc-Associated Autism, Rachel Michelle Reith

Dissertations and Theses (Open Access)

Tuberous sclerosis complex (TSC) is a dominant tumor suppressor disorder caused by mutations in either TSC1 or TSC2. The proteins of these genes form a complex to inhibit the mammalian target of rapamycin complex 1 (mTORC1), which controls protein translation and cell growth. TSC causes substantial neuropathology, often leading to autism spectrum disorders (ASDs) in up to 60% of patients. The anatomic and neurophysiologic links between these two disorders are not well understood. However, both disorders share cerebellar abnormalities. Therefore, we have characterized a novel mouse model in which the Tsc2 gene was selectively deleted from cerebellar Purkinje cells (Tsc2f/-;Cre). …

The New Role Of Proprotein Convertase Subtilisin/Kexin Type 9: A Connection Of Proprotein Convertase Subtilisin/Kexin Type 9, Apolipoprotein B, And Autophagy, Hua Sun

Dissertations and Theses (Open Access)

Plasma low-density lipoprotein (LDL) levels are positively correlated with the incidence of coronary artery disease. In the circulation, the plasma LDL clearance is mainly achieved by the uptake via LDL receptor (LDLR). Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a newly discovered gene, playing an important role in LDL metabolism. Gain-of-function mutations of PCSK9 lead to hypercholesterolemia and loss-of-function mutations of PCSK9 are associated with decrease of LDL cholesterol. The effects of PCSK9 on cholesterol levels are the consequence of a strong interaction between the catalytic domain of PCSK9 and epidermal growth factor-like repeat A (EGF-A) domain of …

Low Reactive Oxygen Species And High Glycolysis In Glioblastoma Stem Cells:Mechanisms And Therapeutic Implications, Feng Wang

Dissertations and Theses (Open Access)

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor with poor prognosis due in part to drug resistance and high incidence of tumor recurrence. The drug resistant and cancer recurrence phenotype may be ascribed to the presence of glioblastoma stem cells (GSCs), which seem to reside in special stem-cell niches in vivo and require special culture conditions including certain growth factors and serum-free medium to maintain their stemness in vitro. Exposure of GSCs to fetal bovine serum (FBS) can cause their differentiation, the underlying mechanism of which remains unknown. Reactive oxygen species (ROS) play an important role …

Role Of Stat3 In Keratinocyte Stem Cells During Skin Tumorigenesis, Dharanija Rao

Dissertations and Theses (Open Access)

STATs play crucial roles in a wide variety of biological functions, including development, proliferation, differentiation, migration and in cancer development. In the present study, we examined the impact of Stat3 deletion or activation on behavior of keratinocytes, including keratinocyte stem cells (KSCs). Deletion of Stat3 specifically in the bulge region of the hair follicle using K15.CrePR1 X Stat3^fl/fl mice led to decreased tumor development by altering survival of bulge region KSCs. To further understand the role of KSCs in skin tumorigenesis, K5.Stat3C transgenic (Tg) mice which express a constitutively active/dimerized form of Stat3 called Stat3C via the bovine keratin …

Targeting Akt/Mtor Signaling Pathways During Murine Skin Tumor Promotion And The Impact Of Dietary Energy Balance Manipulation, Laura A. Checkley

Dissertations and Theses (Open Access)

The prevalence of obesity has continued to rise over the last several decades in the United States lending to overall increases in risk for chronic diseases including many types of cancer. In contrast, reduction in energy consumption via calorie restriction (CR) has been shown to be a potent inhibitor of carcinogenesis across a broad range of species and tumor types. Previous data has demonstrated differential signaling through Akt and mTOR via the IGF-1R and other growth factor receptors across the diet-induced obesity (DIO)/CR spectrum. Furthermore, mTORC1 is known to be regulated directly via nutrient availability, supporting its role in the …

The Functional Organization Of Synaptic Vesicle Pools In A Retinal Bipolar Neuron, Proleta Datta

Dissertations and Theses (Open Access)

Ribbon synapses are found in sensory systems and are characterized by ‘ribbon-like’ organelles that tether synaptic vesicles. The synaptic ribbons co-localize with sites of calcium entry and vesicle fusion, forming ribbon-style active zones. The ability of ribbon synapses to maintain rapid and sustained neurotransmission is critical for vision, hearing and balance. At retinal ribbon synapses, three vesicle pools have been proposed. A rapid pool of vesicles that are docked at the plasma membrane, and whose fusion is limited only by calcium entry, a releasable pool of ATP-primed vesicles whose size also correlates with the number of ribbon-tethered vesicles, and a …

Phenothiazines Induce Abortive Autophagy Leading To Cancer Cell Death, Catherine T. Charles

Dissertations and Theses (Open Access)

Autophagy is an evolutionarily conserved process that functions to maintain homeostasis and provides energy during nutrient deprivation and environmental stresses for the survival of cells by delivering cytoplasmic contents to the lysosomes for recycling and energy generation. Dysregulation of this process has been linked to human diseases including immune disorders, neurodegenerative muscular diseases and cancer.

Autophagy is a double edged sword in that it has both pro-survival and pro-death roles in cancer cells. Its cancer suppressive roles include the clearance of damaged organelles, which could otherwise lead to inflammation and therefore promote tumorigenesis. In its pro-survival role, autophagy allows cancer …

Adherens Junctions And The Actomyosin Network Regulate Organ Growth By Modulating Hippo Pathway Activity In Drosophila, Chih-Chao Yang

Dissertations and Theses (Open Access)

Adherens junctions (AJs) and basolateral modules are important for the establishment and maintenance of apico-basal polarity. Loss of AJs and basolateral module members lead to tumor formation, as well as poor prognosis for metastasis. Recently, in mammalian studies it has been shown that loss of either AJ or basolateral module members deregulate Yorkie activity, the downstream transcriptional effector of the Hippo pathway. Importantly, it is unclear if AJ and basolateral components act through the same or parallel mechanisms to regulate Yorkie activity.

Here, we dissect how loss of AJ and basolateral components affects Hippo signaling in Drosophila. Surprisingly, while …