Digital Commons Network^™

There's Something In The Water: The Inadequacy Of International Anti-Dumping Laws As Applied To The Fukushima Daiichi Radioactive Water Discharge, Darian Ghorbi

American University International Law Review

No abstract provided.

Integrating Sexual Objectification With Object Versus Person Recognition: The Sexualized-Body-Inversion Hypothesis, Philippe Bernard, Sarah J. Gervais, Jill Allen, Sophie Campomizzi, Olivier Klein

Department of Psychology: Faculty Publications

In the study reported here, we tested the novel sexualized-body-inversion hypothesis. Integrating research and theory on objectification and person versus object recognition, we examined whether sexualized women, but not sexualized men, are recognized in the same way as objects are. According to objectification theory (Fredrickson & Roberts, 1997), female bodies are scrutinized and evaluated to a greater degree than male bodies are, which leads to sexual objectification of women. Defined as viewing or treating an individual as a sexualized body, or as sexualized body parts, available for satisfying the needs and desires of other people (Bartky, 1990), sexual objectification has …

Dangerous Separation: An Ecosystem And Way Of Life In The West Bank At The Brink Of Destruction, Elena Katz Mink

PEEL Alumni Scholarship

Israel is currently planning to build the separation wall on the edge of Battir, separating farmers from their fields. If the wall is constructed, residents face the specter of abandoning their way of life and severely restricting their movement, while at the same time the hydrology and ecology of the area will become severely imperiled. In early December, the Israeli Supreme Court (ISC) issued an interim decision ordering the Israeli Defense Ministry (IDM) to submit plans for an alternate route for the wall within ninety days, indicating that the Court is not willing to let Israeli’s security interests override consideration …

Papers Of Shelhamer Family Arc2008-003 - Finding Aid, Shelhamer Family

Finding Aids

No abstract provided.

Out Of One Closet And Into Another: Why Abused Homosexual Males Refrain From Reporting Their Abuse And What To Do About It, Joshua D. Talicska

The Modern American

No abstract provided.

Aesthetics And Art Of Friendship, Sheila Lintott

Faculty Contributions to Books

In the spirit of exploring fresh perspectives, I offer this investigation into the aesthetic aspects of personal relationships with a focus on friendship.1 Glossing the aesthetic aspects of friendship, as we too often do, impoverishes our understanding of the value and meaning of friendships, relationships which give shape and content to our lives, which animate our lives or, as Nancy Sherman (1993) puts it, relationships which structure the good life. The friendships we forge and those we forgo, the loves we cultivate and those we lose, these varying and variable relations broaden (or impoverish) our experiences, intensify (or diminish) our …

Janb2012, Robert Kelly

Robert Kelly Manuscripts

From January 2012 Robert Kelly Archives

Aqueous-Methanolic Extract Of Sweet Flag (Acorus Calamus) Possesses Cardiac Depressant And Endothelial-Derived Hyperpolarizing Factor-Mediated Coronary Vasodilator Effects., Abdul Jabbar Shah, Anwar Gilani

Department of Biological & Biomedical Sciences

This investigation was aimed to probe the pharmacological base of medicinal use of Acorus calamus in ischemic heart diseases. Effect on heart parameters was studied in isolated rabbit heart while coronary vasodilator effect was studied in isolated bovine coronary arterial rings, suspended in tissue baths filled with Krebs solution, maintained at 37degreesC, aerated with carbogen and responses were measured on PowerLab data acquisition system. In Langendorrf's perfused rabbit heart, the crude extract of Acorus calamus (Ac.Cr) at 0.01-10 mg/mL partially suppressed force of ventricular contractions (FVC), heart rate (HR) and coronary flow (CF). The ethylacetate fraction completely suppressed FVC, partially …

Intestinal, Airway, And Cardiovascular Relaxant Activities Of Thymoquinone, Muhammad Nabeel Ghayur, Anwar Hussain Gilani, Luke Jeffrey Janssen

Department of Biological & Biomedical Sciences

Thymoquinone (TQ) is a bioactive component found in many medicinal herbs. In this study, we report the smooth and cardiac muscle relaxant activities of this compound. TQ concentration dependently suppressed spontaneously contracting rabbit jejunum while also relaxed high K+-(80 mM) induced contractions in jejunum and guinea-pig ileum, indicating activity at voltage-operated Ca++ channels (VOCC). Further, TQ displaced Ca++ concentration-response curves, obtained in a Ca++-free environment, to the right, showing blockade of VOCC. Similar activity was observed with verapamil, a standard VOCC blocker. TQ also exhibited nonadrenergic relaxation of agonist-induced contractions in guinea-pig trachea. When tested in fluo-4-loaded mouse lung slices, …

Evaluation Of Gut Modulatory And Bronchodilator Activities Of Amaranthus Spinosus Linn, Mueen Ahmad Chaudhary, Imran Imran, Samra Bashir, Hassan Mehmood, Najeeb-Ur Rehman, Anwarul-Hassan Gilani

Department of Biological & Biomedical Sciences

Background: The aqueous-methanolic extract of Amaranthus spinosus (A. spinosus Linn.,) whole plant, was studied for its laxative, spasmolytic and bronchodilator activities to validate some of its medicinal uses.
Methods: The crude extract of A. spinosus was studied in-vivo for bronchodilator and laxative activities and in-vitro using isolated tissue preparations which were mounted in tissue baths assembly containing physiological salt solutions, maintained at 37°C and aerated with carbogen, to assess the spasmolytic effect and to find out the possible underlying mechanisms.
Results: In the in-vivo experiments in mice, the administration of A. spinosus increased fecal output at doses of 100 …

Not The Power To Destroy: An Effects Theory Of The Tax Power, Neil S. Siegel, Robert D. Cooter

Faculty Scholarship

The Supreme Court’s “new federalism” decisions impose modest limits on the regulatory authority of Congress under the Commerce Clause. According to those decisions, the Commerce Clause empowers Congress to use penalties to regulate interstate commerce, but not to regulate noncommercial conduct. What prevents Congress from penalizing non-commercial conduct by calling a penalty a tax and invoking the Taxing Clause? The only obstacle is the distinction between a penalty and a tax for purposes of Article I, Section 8. In National Federation of Independent Business v. Sebelius (NFIB), the Court considered whether the minimum coverage provision in the Patient …

The Liberty Of Free Riders: The Minimum Coverage Provision, Mill’S “Harm Principle,” And American Social Morality, Jedediah Purdy, Neil S. Siegel

Faculty Scholarship

In this Article, the authors show that cost-shifting and adverse selection problems link the federalism dimension of the debate over the Affordable Care Act to the doctrinally separate and suppressed individual rights dimension. As the scope of these free-rider problems justifies federal power to require individuals to obtain health insurance coverage, so the very existence of the free-rider problems illuminates the difficulty of arguing directly — as opposed to indirectly through the Commerce Clause — that the minimum coverage provision infringes individual liberty. The interdependence between some people’s decisions to forgo insurance and the well-being of other people means that …

Sorrell V. Ims Health And The End Of The Constitutional Double Standard, Ernest A. Young

Faculty Scholarship

No abstract provided.

Not Your Parents' Law Library: A Tale Of Two Academic Law Libraries, Julian Aiken, Femi Cadmus, Fred Shapiro

Faculty Scholarship

As academic law libraries continue to face the inevitability of a rapidly changing landscape which includes a new breed of digital users with sophisticated technological needs, it remains to be seen what libraries will look like in years to come. It is certain that libraries as we know them today will have changed, but to what extent? An ability to remain adaptable and to anticipate the evolving needs of users in a dynamic environment will continue to be key for libraries to remain relevant, and even to survive, in the 21st century; vital to this endeavor will also be an …

Factors Controlling Macondo Oil Biodegraqdation On A Rapidly Eroding Coastal Headlands Beach, Marilany G. Urbano

LSU Master's Theses

Fourchon Beach, located along the southeast Louisiana coast, was affected by the oil leaking from the British Petroleum’s Deepwater Horizon Oil rig explosion in 2010. The oil, labeled MC252 oil, came ashore in a stable emulsion form, contaminating the sand, salt pan, marsh and mangroves along the beach. A unique oil form, labeled SSRB (small surface residue ball) was formed from the MC252 oil and a combination of environmental factors. The SSRB is an aggregate of sand and emulsified oil, and forms a large portion of the oil still present on the supratidal zone of Fourchon Beach. SSRBs have not …

Instability In A Generalized Keller–Segel Model, Patrick De Leenheer, Jay Gopalakrishnan, Erica Zuhr

Mathematics and Statistics Faculty Publications and Presentations

We present a generalized Keller–Segel model where an arbitrary number of chemical compounds react, some of which are produced by a species, and one of which is a chemoattractant for the species. To investigate the stability of homogeneous stationary states of this generalized model, we consider the eigenvalues of a linearized system. We are able to reduce this infinite dimensional eigenproblem to a parametrized finite dimensional eigenproblem. By matrix theoretic tools, we then provide easily verifiable sufficient conditions for destabilizing the homogeneous stationary states. In particular, one of the sufficient conditions is that the chemotactic feedback is sufficiently strong. Although …

Second Things First: What Free Speech Can And Can’T Say About Guns, Joseph Blocher

Faculty Scholarship

Professor Blocher responds to Gregory Magarian’s article on the implications of the First Amendment for the Second.

Antimicrobial Peptides As Therapeutic Agents., Mathew Upton, Paul Cotter, John Tagg

School of Biomedical Sciences

No abstract provided.

Huntington's Disease And Its Therapeutic Target Genes: A Global Functional Profile Based On The Hd Research Crossroads Database, Ravi Kiran R. Kalathur, Miguel A. Hernández-Prieto, Matthias E. Futschik

School of Biomedical Sciences

Abstract Background Huntington’s disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pathogenesis. To obtain a systematic overview of these genes, which may serve as therapeutic targets, CHDI Foundation has recently established the HD Research Crossroads database. With currently over 800 cataloged genes, this web-based resource constitutes the most extensive curation of genes relevant to HD. It provides us with an unprecedented opportunity to survey molecular mechanisms …

Personality And Metamorphosis: Is Behavioral Variation Consistent Across Ontogenetic Niche Shifts?, Alexander D.M. Wilson, Jens Krause

School of Biological and Marine Sciences

No abstract provided.

Moving Image Production And The Pedagogical Development Of Media Literacy, K Parker, L French, S Moore

School of Art, Design and Architecture

No abstract provided.

Towards Sustainable Communities And Human Security: Challenges Of The College Of Public Affairs And Development University Of The Philippines Los Baños, Agnes C. Rola, Josefina T. Dizon, Maria Ana T. Quimbo, Wilfredo B. Carada

Journal of Public Affairs and Development

The College of Public Affairs (CPAf) in the University of the Philippines Los Baños (UPLB) evolved as a unit of the University with the mandate to raise the bar of applied social science scholarship by developing transdisciplinary methods in the resolution of public issues such as food security, land reform and land use, governance, population, and education. The creation of CPAf in 1998 was prompted “by the need to attune academic programs in the pursuit of UP’s mission to promote nationalism and development in the face of profound changes occurring in the global environment.” In 2011, it was renamed as …

Ecotoxicology, Valery E. Forbes, Peter Calow

Valery Forbes Publications

Ecotoxicology is concerned with describing, understanding, and predicting the effects of chemicals used by people, either from natural sources (such as metals) or from synthetic processes (agrochemicals, pharmaceuticals, industrial chemicals), on ecological systems. It provides the basis for ecological risk assessment, predicting likely impacts of chemicals on ecological systems, and is an important contributor to environmental protection legislation. ...

Theoretical models have an important part to play in ecotoxicology, because it is extremely difficult to predict the likely effects of chemicals in complex ecological systems simply on the basis of observation. Ecological models that incorporate mechanistic understanding of the appropriate …

Keratinocyte-Targeted Expression Of Human Laminin Γ2 Rescues Skin Blistering And Early Lethality Of Laminin Γ2 Deficient Mice., Tracy L Adair-Kirk, Gail L Griffin, Michelle J Meyer, Diane G Kelley, Jeffrey H Miner, Douglas R Keene, M Peter Marinkovich, J Michael Ruppert, Jouni Uitto, Robert M Senior

Department of Dermatology and Cutaneous Biology Faculty Papers

Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and adult tissues. In skin, laminin-332 is secreted by keratinocytes and is a key component of hemidesmosomes connecting the keratinocytes to the underlying dermis. In mice, lack of expression of any of the three Laminin-332 chains result in impaired anchorage and detachment of the epidermis, similar to that seen in human junctional epidermolysis bullosa, and death occurs within a few days after birth. To bypass the early …

Administration Of Bone Marrow Derived Mesenchymal Stem Cells Into The Liver: Potential To Rescue Pseudoxanthoma Elasticum In A Mouse Model (Abcc6-/-)., Qiujie Jiang, Shunsuke Takahagi, Jouni Uitto

Department of Dermatology and Cutaneous Biology Faculty Papers

Pseudoxanthoma elasticum (PXE) is a heritable ectopic mineralization disorder caused by loss-of-function mutations in the ABCC6 gene which is primarily expressed in the liver. There is currently no effective treatment for PXE. In this study, we characterized bone marrow derived mesenchymal stem cells (MSCs) and evaluated their ability to contribute to liver regeneration, with the aim to rescue PXE phenotype. The MSCs, isolated from GFP-transgenic mice by magnetic cell sorting, were shown to have high potential for hepatic differentiation, with expression of Abcc6, in culture. These cells were transplanted into the livers of 4-week-old immunodeficient Abcc6⁻/⁻ mice by intrasplenic injection …

The Role Of Ecological Models In Linking Ecological Risk Assessment To Ecosystem Services In Agroecosystems, Nika Galic, Amelie Schmolke, Valery E. Forbes, Hans Baveco, Paul Van Den Brink

Valery Forbes Publications

Agricultural practices are essential for sustaining the human population, but at the same time they can directly disrupt ecosystem functioning. Ecological risk assessment (ERA) aims to estimate possible adverse effects of human activities on ecosystems and their parts. Current ERA practices, however, incorporate very little ecology and base the risk estimates on the results of standard tests with several standard species. The main obstacles for a more ecologically relevant ERA are the lack of clear protection goals and the inherent complexity of ecosystems that is hard to approach empirically. In this paper, we argue that the ecosystem services framework offers …

Effects Of Sediment-Associated Copper To The Deposit-Feeding Snail, Potamopyrgus Antipodarum: A Comparison Of Cu Added In Aqueous Form Or As Nano- And Micro-Cuo Particles, Chengfang Pang, Henriette Selck, Superb K. Misra, Deborah Berhanu, Agnieszka Dybowska, Eugenia Valsami-Jones, Valery E. Forbes

Valery Forbes Publications

Increasing use of engineered nanoparticles (NPs) is likely to result in release of these particles to the aquatic environment where the NPs may eventually accumulate in sediment. However, little is known about the potential ecotoxicity of sediment-associated engineered NPs. We here consider the case of metal oxide NPs using CuO to understand if the effects of NPs differ from micron-sized particles of CuO and aqueous Cu (CuCl₂). To address this issue, we compared effects of copper added to the sediment as aqueous Cu, nano- (6 nm) and micro- (μm) CuO particles on the deposit-feeding snail, Potamopyrgus antipodarum. …

Development Of A Framework Based On An Ecosystem Services Approach For Deriving Specific Protection Goals For Environmental Risk Assessment Of Pesticides, Karin M. Nienstedt, Theo C. M. Brock, Joke Van Wensem, Mark Montforts, Andy Hart, Alf Aagaard, Anne Alix, Joes Boesten, Stephanie K. Bopp, Colin Brown, Ettore Capri, Valery E. Forbes, Herbert Köpp, Matthias Liess, Robert Luttik, Lorraine Maltby, José P. Sousa, Franz Streissl, Anthony R. Hardy

Valery Forbes Publications

General protection goals for the environmental risk assessment (ERA) of plant protection products are stated in European legislation but specific protection goals (SPGs) are often not precisely defined. These are however crucial for designing appropriate risk assessment schemes. The process followed by the Panel on Plant Protection Products and their Residues (PPR) of the European Food Safety Authority (EFSA) as well as examples of resulting SPGs obtained so far for environmental risk assessment (ERA) of pesticides is presented. The ecosystem services approach was used as an overarching concept for the development of SPGs, which will likely facilitate communication with stakeholders …

Transnational Conservation Contracts, Natasha Affolder

All Faculty Publications

Transnational environmental law is the subject of growing scholarly interest. Yet, much work remains to be done to fill in both the conceptual and empirical contours of this field. One methodological challenge that transnational law poses is the need to look beyond traditional sources of international and national law. This article contributes to efforts to understand transnational law's multilayered architecture by drawing attention to the use of transnational contracts as a mechanism to protect habitats and species. The diverse and proliferating examples of conservation contracts discussed in this article – which include forest carbon agreements, conservation concessions, debt-for-nature swaps, conservation …

Transport And Partitioning Of Organochlorine Pollutants In The Open Oceans, Lin Zhang

Open Access Dissertations

Remote open oceans were traditionally considered as sinks of persistent organic pollutants (POPs) such as industrial chemicals (PCBs) and organochlorine pesticides (OCPs). In the context of reduced primary emissions as well as global warming, previous polluted reservoirs such as soil, large water bodies, and glaciers may act as secondary sources returning these POPs back to the atmosphere and ocean. It was also hypothesized that biogeochemical activities associated with phytoplankton in the water column would lead to the coupling of air-plankton systems to draw down the lipophilic POPs from the overlying atmosphere, similar to the biological pump taking up CO_{2 …}