Digital Commons Network^™

Bop5 Mutations Reveal New Roles For The Ic138 Phosphoprotein In The Regulation Of Flagellar Motility And Asymmetric Waveforms, Kristyn E. Vanderwaal, Ryosuke Yamamoto, Ken-Ichi Wakabayashi, Laura Fox, Ritsu Kamiya, Susan K. Dutcher, Phillip V. Bayly, Winfield S. Sale, Mary E. Porter

Open Access Publications

No abstract provided.

New Tools And Methods For Direct Programmatic Access To The Dbsnp Relational Database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, John P. Rice

Open Access Publications

No abstract provided.

2011 - 105th Annual Summit, "Enough: Isaiah 1:11-17", Abilene Christian University, Abilene Christian University

Lectureship and Summit Programs

No abstract provided.

Was Mechanization De-Skilling? The Origins Of Task-Biased Technical Change, James Bessen

Faculty Scholarship

Did nineteenth century technology reduce demand for skilled workers in contrast to modern technology? I obtain direct evidence on human capital investments and the returns to skill by using micro-data on individual weavers and an engineering production function. Weavers learned substantially on the job. While mechanization eliminated some tasks and the associated skills, it increased returns to skill on the remaining tasks. Technical change was task-biased, much as with computer technology. As more tasks were automated, weavers’ human capital increased substantially. Although technology increased the demand for skill like today, weavers’ wages eventually increased and inequality decreased, contrary to current …

Ethical Issues In Business And The Lawyer's Role, Robert Rhee, Carol Morgan, Tamar Frankel, Mark Fagan

Faculty Scholarship

Q&A with Robert Rhee, Carol Morgan, Tamar Frankel, and Mark Fagan regarding courses focused on business ethics.

/="/">

Good afternoon everyone. I am Carol Morgan. I am with the University of Georgia School of Law's Business Law and Ethics program. I'm joined today by very distinguished panelists, Tamar Frankel from Boston University and Robert Rhee from the University of Maryland. You will hear a lot more about them during our program today. I am glad to see this interest in the topic of business ethics. Law schools have not traditionally put a lot of attention or focus on the subject …

Type I Interferon Is Selectively Required By Dendritic Cells For Immune Rejection Of Tumors, Mark S. Diamond, Michelle Kinder, Hirokazu Matsushita, Mona Mashayekhi, Gavin P. Dunn, Jessica M. Archambault, Hsiaoju Lee, Cora D. Arthur, J Michael White, Ulrich Kalinke, Kenneth M. Murphy, Robert D. Schreiber

Open Access Publications

Cancer immunoediting is the process whereby the immune system suppresses neoplastic growth and shapes tumor immunogenicity. We previously reported that type I interferon (IFN-α/β) plays a central role in this process and that hematopoietic cells represent critical targets of type I IFN's actions. However, the specific cells affected by IFN-α/β and the functional processes that type I IFN induces remain undefined. Herein, we show that type I IFN is required to initiate the antitumor response and that its actions are temporally distinct from IFN-γ during cancer immunoediting. Using mixed bone marrow chimeric mice, we demonstrate that type I IFN sensitivity …

Cd103+ Pulmonary Dendritic Cells Preferentially Acquire And Present Apoptotic Cell-Associated Antigen, A Nicole Desch, Gwendalyn J. Randolph, Kenneth Murphy, Emmanuel L. Gautier, Ross M. Kedl, Mireille H. Lahoud, Irina Caminschi, Ken Shortman, Peter M. Henson, Claudia V. Jakubzick

Open Access Publications

Cells undergoing programmed cell death (apoptosis) are removed in situ by macrophages and dendritic cells (DCs) through a specialized form of phagocytosis (efferocytosis). In the lung, there are two primary DC subsets with the potential to migrate to the local lymph nodes (LNs) and initiate adaptive immune responses. In this study, we show that only CD103(+) DCs were able to acquire and transport apoptotic cells to the draining LNs and cross present apoptotic cell-associated antigen to CD8 T cells. In contrast, both the CD11b(hi) and the CD103(+) DCs were able to ingest and traffic latex beads or soluble antigen. CD103(+) …

Innate And Cytokine-Driven Signals, Rather Than Microbial Antigens, Dominate In Natural Killer T Cell Activation During Microbial Infection, Manfred Brigl, Raju V.V. Tatituri, Gerald F.M. Watts, Veemal Bhowruth, Elizabeth A. Leadbetter, Nathaniel Barton, Nadia R. Cohen, Fong-Fu Hsu, Gurdyal S. Besra, Michael B. Brenner

Open Access Publications

Invariant natural killer T cells (iNKT cells) are critical for host defense against a variety of microbial pathogens. However, the central question of how iNKT cells are activated by microbes has not been fully explained. The example of adaptive MHC-restricted T cells, studies using synthetic pharmacological α-galactosylceramides, and the recent discovery of microbial iNKT cell ligands have all suggested that recognition of foreign lipid antigens is the main driver for iNKT cell activation during infection. However, when we compared the role of microbial antigens versus innate cytokine-driven mechanisms, we found that iNKT cell interferon-γ production after in vitro stimulation or …

Barth Syndrome Mutations That Cause Tafazzin Complex Lability, Steven M. Claypool, Kevin Whited, Santi Srijumnong, Xianlin Han, Carla M. Koehler

Open Access Publications

Deficits in mitochondrial function result in many human diseases. The X-linked disease Barth syndrome (BTHS) is caused by mutations in the tafazzin gene TAZ1. Its product, Taz1p, participates in the metabolism of cardiolipin, the signature phospholipid of mitochondria. In this paper, a yeast BTHS mutant tafazzin panel is established, and 18 of the 21 tested BTHS missense mutations cannot functionally replace endogenous tafazzin. Four BTHS mutant tafazzins expressed at low levels are degraded by the intermembrane space AAA (i-AAA) protease, suggesting misfolding of the mutant polypeptides. Paradoxically, each of these mutant tafazzins assembles in normal protein complexes. Furthermore, in the …

Holiness Is Power, Acts 1:8, Part 2, Susie Cunninham Stanley

ATS Chapel Services

No abstract provided.

Bible Study: I Peter 2:18-3:7, C. K. Barrett

ATS Chapel Services

No abstract provided.

Bible Study: 1 Peter 3:8-22, C. K. Barrett

ATS Chapel Services

No abstract provided.

The Good Shepherd, John Slater

ATS Chapel Services

No abstract provided.

A Comparison And Cooperative Utilization Of Møller–Plesset Perturbation Theory And B3lyp Density Functional Theory On Weakly Bound Structures, Joshua Ryan Smith

Honors Theses

Harold Burson is the founder of Burson-Marsteller, a New York-based public relations firm, and has been recognized by PRWeek as "the century's most influential PR figure." He has received numerous awards from different organizations, run one of the largest public relations firm in the world, helped the field of public relations become a prominent profession and was one of the first individuals to push for international firms among other things. This thesis tries to reveal why so many see Harold Burson as a leader who has revolutionized the field. This is accomplished through interviewing friends, colleagues and family of Harold …

Examination Of The Consumer Ethics Of Students At The University Of Mississippi, Stephen Cole Wilkerson

Honors Theses

Consumer perceives a . in this a random sample of one hundred fifty-seven students reaction he study, in the College of Liberal Arts and the School of Business urveyed using the Consumer Ethics Scale devised by Vitell and Dr. James Muncy. Scale devised by Dr. Americus Reed and Dr. if any difference existed in the were s Dr. Scott The Moral Identity Karl Aquino was also used to see in which different majors perceive themselves. The results provided no significant there was a difference. way or want ot to perceive them. evidence that using a 0.05 hers significance level. There …

Viridis: Green Living In The South”, Mary Elizabeth White

Honors Theses

Viridis magazine is a Southern cooking and lifestyle magazine centered around food, products, and places that are good for the body, good for the Earth, and good for personal wellness. Each issue, Viridis highlights interesting people, places, recipes, and consumer products all over the Southern United States that reflect a green, eco-conscious lifestyle of eating and living. It aims at Southerners who are proud of their region of the country and love being southern, but still care about what they eat and how they live.

Genome-Wide Identification And Quantification Of Cis- And Trans-Regulated Genes Responding To Marek’S Disease Virus Infection Via Analysis Of Allele-Specific Expression, Sean Maceachern, William M. Muir, Seth D. Crosby, Hans H. Cheng

Open Access Publications

No abstract provided.

The Tumor Suppressor Gene Trp53 Protects The Mouse Lens Against Posterior Subcapsular Cataracts And The Bmp Receptor Acvr1 Acts As A Tumor Suppressor In The Lens, Luke A. Wiley, Ramya Rajagopal, Lisa K. Dattilo, David C. Beebe

Open Access Publications

No abstract provided.

Transforming Evil With Dr. King, Keith Jagger

ATS Chapel Services

No abstract provided.

Year In Review 2010: Critical Care- Neurocritical Care, Michael T. Scalfani, Michael N. Diringer

Open Access Publications

No abstract provided.

Secret In Suffering, Jeannine Brabon

ATS Chapel Services

No abstract provided.

Effect Of Supplementation During Pregnancy With L-Arginine And Antioxidant Vitamins In Medicalfood On Pre-Eclampsia In High Risk Population: Randomised Controlled Trial, Felipe Vadillo-Ortega, Otilia Perichant-Perera, Salvador Espino, Marco Antonio Avila-Vergara, Isabel Ibarra, Roberto Ahued, Myrna Godines, Samuel Parry, George Macones, Jerome F. Strauss

Open Access Publications

No abstract provided.

He Chief Prosecutor Is Sacked, Timothy C. Tennent

ATS Chapel Services

No abstract provided.

The Jonah Complex, George G. Hunter Iii

ATS Chapel Services

No abstract provided.

Seeing Only Jesus (February 09, 2010), Timothy C. Tennent

ATS Chapel Services

No abstract provided.

Seeing Only Jesus (March 23, 2010), Mike Watson

ATS Chapel Services

No abstract provided.

Bcl3 Prevents Acute Inflammatory Lung Injury In Mice By Restraining Emergency Granulopoiesis, Daniel Kreisel, Seiichiro Sugimoto, Jeremy Tietjens, Jihong Zhu, Sumiharu Yamamoto, Alexander S. Krupnick, Ruaidhri J. Carmody, Andrew E. Gelman

Open Access Publications

No abstract provided.

Rna Sensor-Induced Type I Ifn Prevents Diabetes Caused By A Β Cell-Tropic Virus In Mice, Stephen A. Mccartney, William Vermi, Silvia Lonardi, Cristina Rossini, Karel Otero, Boris Calderon, Susan Gilfillan, Michael S. Diamond, Emil R. Unanue, Marco Colonna

Open Access Publications

No abstract provided.

Notch1 Loss Of Heterozygosity Causes Vascular Tumors And Lethal Hemorrhage In Mice, Zhenyi Liu, Ahu Turkoz, Erin N. Jackson, Joseph C. Corbo, John A. Engelbach, Joel R. Garbow, David R. Piwnica-Worms, Raphael Kopan

Open Access Publications

No abstract provided.

Harvesting Intellectual Property: Inspired Beginnings And 'Work-Makes-Work,' Two Stages In The Creative Processes Of Artists And Innovators, Jessica Silbey

Faculty Scholarship

This Article is part of a larger empirical study based on face-to-face interviews with artists, scientists, engineers, their lawyers, agents, and business partners. The book-length project involves the collecting and analysis of stories from artists, scientists, and engineers about how and why they create and innovate. It also collects stories from their employers, business partners, managers, and lawyers about their role in facilitating the process of creating and innovating. The book’s aim is to make sense of the intersection between intellectual property law and creative and innovative activity, specifically to discern how intellectual property intervenes in the careers of the …