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Evaluation Of The Reproductive And Developmental Risks Of Caffeine., Robert L Brent, Mildred S Christian, Robert M Diener

Department of Pediatrics Faculty Papers

A risk analysis of in utero caffeine exposure is presented utilizing epidemiological studies and animal studies dealing with congenital malformation, pregnancy loss, and weight reduction. These effects are of interest to teratologists, because animal studies are useful in their evaluation. Many of the epidemiology studies did not evaluate the impact of the "pregnancy signal," which identifies healthy pregnancies and permits investigators to identify subjects with low pregnancy risks. The spontaneous abortion epidemiology studies were inconsistent and the majority did not consider the confounding introduced by not considering the pregnancy signal. The animal studies do not support the concept that caffeine …

Rapid Detection And E-Test Antimicrobial Susceptibility Testing Of Vibrio Parahaemolyticus Isolated From Seafood And Environmental Sources In Malaysia, Saleh M. Al-Othrubi, Alfizah Hanafiah, Son Radu, Humin Neoh, Rahaman Jamal

Saudi Medical Journal

OBJECTIVE: To find out the prevalence and antimicrobial susceptibility of Vibrio parahaemolyticus in seafoods and environmental sources. METHODS: The study was carried out at the Center of Excellence for Food Safety Research, University Putra Malaysia; Universiti Kebangsaan Malaysia; Medical Molecular Biology Institute; and University Kebansaan Malaysia Hospital, Malaysia between January 2006 and August 2008. One hundred and forty-four isolates from 400 samples of seafood (122 isolates) and seawater sources (22 isolates) were investigated for the presence of thermostable direct hemolysin (tdh+) and TDH-related hemolysin (trh+) genes using the standard methods. The E-test method was used to test the antimicrobial susceptibility. …

The Importance Of Immutability In Employment Discrimination Law, Sharona Hoffman

William & Mary Law Review

This Article argues that recent developments in employment discrimination law require a renewed focus on the concept of immutable characteristics. In 2009, two new laws took effect: the Genetic Information Nondiscrimination Act (GINA) and the Americans with Disabilities Act Amendments Act (ADAAA). This Article’s original contribution is an evaluation of the employment discrimination statutes as a corpus of law in light of these two additions.

The Article thoroughly explores the meaning of the term “immutable characteristic” in constitutional and employment discrimination jurisprudence. It postulates that immutability constitutes a unifying principle for all of the traits now covered by the employment …

Philosophy And Theology: Notes On Conscience Protections For Health Care Workers, Christopher Kaczor

Philosophy Faculty Works

The article reviews reports on the philosophy and theology of bio ethics, including "Is Conscientious Objection Incompatible with a Physician's Professional Obligations?" and "Negative and Positive Claims of Conscience," both by Mark R. Wicclair, published in the January 2009 issue of "Cambridge Quarterly of Health Care Ethics." Wicclair discusses the incompatibility thesis. The article also observes that the contemporary debate on conscience protection has intensified.

Eating For Two: A Study Of The Effects Of Obesity Upon The Health Of Pregnant Women And Their Infants, Michael Cochran-Boucher

Inquiry Journal 2011

No abstract provided.

Action And Applications Of Antibacterial Peptides, Kulwadee Phannachet

Asian Medical Journal and Alternative Medicine

Antibacterial peptides are produced by various organisms from insects to mammals. Modes of action of these peptides for killing bacteria depend on their structures, charges and amino acid compositions. Attraction and attachment of peptides on surface of bacteria by charge-charge interaction followed by cell membrane insertion. Bacteria death is caused either by the transmembrane pore-forming or intracellular killing mechanisms. Therapeutic uses of antibacterial peptides especially for dealing with antibiotic resistance problem are still in the preclinical phase and needed the intensively study on the advantages and disadvantages.

Some Women's Work: Domestic Work, Class, Race, Heteropatriarchy, And The Limits Of Legal Reform, Terri Nilliasca

Michigan Journal of Race and Law

This Note employs Critical Race, feminist, Marxist, and queer theory to analyze the underlying reasons for the exclusion of domestic workers from legal and regulatory systems. The Note begins with a discussion of the role of legal and regulatory systems in upholding and replicating White supremacy within the employer and domestic worker relationship. The Note then goes on to argue that the White, feminist movement's emphasis on access to wage labor further subjugated Black and immigrant domestic workers. Finally, I end with an in-depth legal analysis of New York's Domestic Worker Bill of Rights, the nation's first state law to …

Fitting Model Parameters To Patient Data Automatically Through Evolutionary Computation, Michael Wesley Sagan

Master's Theses (2009 -)

The Orthopaedic and Rehabilitation Engineering Center (O.R.E.C) has been studying two conditions which can wreak havoc on the human body's balance control system. The conditions being studied are cerebral palsy (CP) and adolescent idiopathic scoliosis (AIS)[1, 2, 3, 4, 5, 6]. A greater understanding of postural deficits in children with these conditions and the causes for these conditions may help researchers achieve better interventions and treatments [3]. A tool used to characterize postural stability is a bi-planar postural stability model. This model is designed where 10 parameter values have to be adjusted until the simulated data is statistically the same …

Bistro-Primer - Tool To Design And Validate Specific Pcr Primer Pairs For Phylogenetic Analysis, Praful Aggarwal

Master's Theses (2009 -)

Polymerase Chain Reaction is a widely used biological technique which helps in amplifying small quantities of DNA. These amplified DNA copies are then used in several other experiments like DNA sequencing, phylogenetic analysis, etc. PCR primers are short subsequences of nucleotides (basic unit of DNA) that help identify larger regions of the DNA sequence. They help in successfully amplifying the target DNA sequence by identifying complementary regions on the DNA template. Therefore, to successfully perform PCR it is imperative to design good quality primers.

PCR can be used for identifying the phylogenetic classification of an organism. For example, in an …

Reactivity Of Acyclic (Pentadienyl) Iron (1+) Cations With Phosphorous-Stabilized Carbon Nucleophiles And With Nitrogen Nucleophiles, Yuzhi Ma

Master's Theses (2009 -)

A lot of studies regard organoiron compounds have been made in recent years. Nucleophilic addition with soft nucleophiles such as malonate anions or phosphonate stabilized carbon nucleophiles, or harder nucleophiles such as organolithium or Grignard reagents to an acyclic (pentadienyl)iron cation results in the (pentenediyl)iron complexes.

Reaction of (pentadienyl)iron complexes with paraformaldehyde via Horner-Emmons olefination will give enolate complex. Oxidation of the enolate leads to the formation of cyclopropane carboxylates. Further oxidation of divinyl cyclopropane carboxylates can form cycloheptadiene.

The reactivity of acyclic (pentadienyl)iron cations with nitrogen nucleophiles such as potassium phthalimide were examined, which could be used as potential …

Potent Inhibition Of Heterotopic Ossification By Nuclear Retinoic Acid Receptor-Γ Agonists., Kengo Shimono, Wei-En Tung, Christine Macolino, Amber Hsu-Tsai Chi, Johanna H Didizian, Christina Mundy, Roshantha A Chandraratna, Yuji Mishina, Motomi Enomoto-Iwamoto, Maurizio Pacifici, Masahiro Iwamoto

Department of Orthopaedic Surgery Faculty Papers

Heterotopic ossification consists of ectopic bone formation within soft tissues after surgery or trauma. It can have debilitating consequences, but there is no definitive cure. Here we show that heterotopic ossification was essentially prevented in mice receiving a nuclear retinoic acid receptor-γ (RAR-γ) agonist. Side effects were minimal, and there was no significant rebound effect. To uncover the mechanisms of these responses, we treated mouse mesenchymal stem cells with an RAR-γ agonist and transplanted them into nude mice. Whereas control cells formed ectopic bone masses, cells that had been pretreated with the RAR-γ agonist did not, suggesting that they had …

A Conceptual Model For Employer Training To Manage Employee Counter-Productive Behaviors, Naomi Spickard Rock

STEMPS Theses & Dissertations

The purpose of this study was to develop a model for employer training to manage employees who possess counter-productive behaviors. With the increasing encouragement for employers to hire without discriminating, the number of individuals with disabilities in the workforce will rise. There is limited training in universities and businesses to teach how to deal with difficult individuals.

Qualitative research in the form of focus groups was conducted. The following research objectives were developed: 1) Identify components of counter-productive behaviors that need to be managed in the workplace. 2) Develop behavioral management strategies that need be learned by employers. 3) Integrate …

Modeling The Contagion Effect Of Foreclosures Within The Real Estate Market By Use Of Agent-Based Modeling And Simulation, Marshall William Gangel

Computational Modeling & Simulation Engineering Theses & Dissertations

Over the last several years, the US financial and real estate markets have experienced a significant recession. During this downturn, the number of real estate foreclosures rose drastically. Recent studies have empirically demonstrated a reduction in real estate values due to foreclosures. The observed reduction in the average value of real estate properties has been labeled the foreclosure contagion effect. The foreclosure contagion effect impacts healthy neighboring properties that surround the foreclosed property as a function of time and distance.

This study uses an agent-based modeling and simulation (ABMS} approach to explore the contagion effect of foreclosures. For this research, …

Resources Inventory Of Beef And Dairy Operations For The Use Of Ethanol Coproducts, Julie I. Navarro, Lori J. Unruh Snyder, Ronald P. Lemenager, Matthew C. Claeys

Journal of Extension

To remain competitive in the industry, beef and dairy producers in the Midwest need to adapt to the use of alternative feeds and take advantage of the expected abundance and favorable pricing of biofuel coproducts. Integrating the coproducts as feed ingredients could make the livestock industry significantly more attractive and competitive in domestic and global markets. A survey instrument was created to inventory resources that currently limit (or enable) the use of biofuel coproducts by small and medium-sized beef and dairy producers in the state of Indiana. Seventy-eight of Indiana's 92 counties were represented in the survey results.

Computational Investigation Of The Bioactive Selenium Compounds Ebselen And Selenious Acid, Sonia Antony

Chemistry & Biochemistry Theses & Dissertations

Selenium, a toxic element, is required in trace quantities for the proper functioning of biological systems. The experimental mechanistic study of the reactions of ebselen and selenious acid is difficult due to complexity of the reaction mixtures and the presence of short-lived intermediates. Computational modeling of the reactivity of these species can give us an insight into their mechanisms, but the process is complicated by proton exchanges associated with the mechanistic steps. In gas phase modeling, this may be corrected to a certain level using the solvent assisted proton exchange (SAPE) method. SAPE is a modeling technique that mimics solvent …

Deficits In Adults With Autism Spectrum Disorders When Processing Multiple Objects In Dynamic Scenes, Kirsten O'Hearn, Laura Lakusta, Elizabeth Schroer, Nancy Minshew, Beatriz Luna

Department of Psychology Faculty Scholarship and Creative Works

People with autism spectrum disorders (ASD) process visual information in a manner that is distinct from typically developing individuals. They may be less sensitive to people's goals and, more generally, focus on visual details instead of the entire scene. To examine these differences, people with and without ASD were asked to detect changes in dynamic scenes with multiple elements. Participants viewed a brief video of a person or an inanimate object (the "figure") moving from one object to another; after a delay, they reported whether a second video was the same or different. Possible changes included the figure, the object …

Law For The Common Man: An Individual-Level Theory Of Values, Expanded Rationality, And The Law , Amir N. Licht

Law and Contemporary Problems

This article makes an admittedly bold attempt at outlining an analytical framework for addressing this question. Instead of looking at the legal implications of bounded rationality -- an exercise highly worthy in its own right -- this article advances a theory of expanded rationality. This theory retains the element of rationality in that people respond to incentives in an attempt to attain utility, and it does not question the observation that decision-making is often bounded due to various factors.

From Divergence To Convergence? A Comparative And International Law Analysis Of Lgbti Rights In The Context Of Race And Post-Colonialism, James D. Wilets

Duke Journal of Comparative & International Law

No abstract provided.

Environmental Health Science For Regulatory Decisionmaking, Linda S. Birnbaum, Paul Jung, Sheila A. Newton

Duke Environmental Law & Policy Forum

No abstract provided.

Epa At 40: Reflections On The Office Of Research And Development, Bernard D. Goldstein Md

Duke Environmental Law & Policy Forum

No abstract provided.

How Reins Would Improve Environmental Protection, David Schoenbrod

Duke Environmental Law & Policy Forum

No abstract provided.

Innovation In The Auto Industry: The Role Of The U.S. Environmental Protection Agency, Sanya Carley, Natalie Messer Betts, John D. Graham

Duke Environmental Law & Policy Forum

No abstract provided.

Macro-Risks: The Challenge For Rational Risk Regulation, Michael P. Vandenbergh, Jonathan A. Gilligan

Duke Environmental Law & Policy Forum

No abstract provided.

The Women’S Convention, Reproductive Rights, And The Reproduction Of Gender, Barbara Stark

Duke Journal of Gender Law & Policy

No abstract provided.

The ‘State’ Of Surrogacy Laws: Determinations Of Legal Parenthood For Gay Fathers, Anne R. Dana

Duke Journal of Gender Law & Policy

No abstract provided.

Examining Gender Stereotypes In New Work/Family Reconciliation Policies: The Creation Of A New Paradigm For Egalitarian Legislation, Rangita De Silva De Alwis

Duke Journal of Gender Law & Policy

No abstract provided.

The New Uniform Probate Code’S Surprising Gender Inequities, Kristine S. Knaplund

Duke Journal of Gender Law & Policy

No abstract provided.

Cracks In The Cost Structure Of Agency Adoption, Andrea B. Carroll

Journal Articles

No abstract provided.

Tyranny, Marriage, And A New Market, William Holden

Anthós

This will be an explication of John Stuart Mill’s Autobiography along with a discussion of its relationship to the works of Jean Jacques Rousseau in regards to the models of gender and womanhood painted by each thinker in his texts. First, I will offer a quantified taxonomy of several formal structures in Mill’s text, including a summary of the uses of the phrase “my father” alongside a summary of the instances of Mill’s claims of having read an author. Next, I give a summary of the uses of the phrases “my wife” and “my daughter” alongside a discussion of the …

A Statistical Comparison Of First Time Praxis Ii Pass Rates Between Homegrown 4 Year Students And Transfer Students Of A Medium Size Suburban University: A Six Year Study, Jason Edward Holmes Jr.

Dissertations

In order to meet the federal mandate specified by the No Child Left Behind Act to demonstrate content competency for teaching certification, students must pass a written examination. Missouri and 37 other states chose the Praxis II to satisfy requirements. Presently, schools of education advertise the passing rate of the Praxis II as 100%, since students can take the Praxis II until they pass. This study examined only the first time Praxis II pass rates for undergraduate students in a medium sized university over a six year period. The quantitative, predictive non-experimental research study statistically analyzed first time Praxis II …