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2011

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An Exploration Of The Earthen Feminine : The Vessel., Sharon Madison 1955- May 2011

An Exploration Of The Earthen Feminine : The Vessel., Sharon Madison 1955-

Electronic Theses and Dissertations

Clay has been an integral part of my life from early childhood. The attempts of five-year-old hands to create vessels always ended up failures in my young eyes. Having had the blessings in my life to study under Richard Burns and the Master, Tom Marsh, I have learned to create, in permanency, the kinds of vessels my five-year-old heart yearned for. My exploration in the study of ceramics has been, and always will be, the center of my life in art. This exploration has brought me from the functional to an exaggeration of the functional. A way from the wheel, …

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A Predictive Model For Mssw Student Success., Angela Michele Napier May 2011

A Predictive Model For Mssw Student Success., Angela Michele Napier

Electronic Theses and Dissertations

This study tested a hypothetical model for predicting both graduate GPA and graduation of University of Louisville Kent School of Social Work Master of Science in Social Work (MSSW) students entering the program during the 2001-2005 school years. The preexisting characteristics of demographics, academic preparedness and culture shock along with the subjective experiences of academic stability and academic performance were studied. A hierarchical multiple regression analysis was used to determine the best predictors of final GPA. The best predictors were age, undergraduate GPA, differences between undergraduate and graduate institution size, continuity index, and the course completion ratio. A hierarchical logistic …

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Pattern Play : Pieced Works On Paper., Gweneth A. Dunleavy 1954- May 2011

Pattern Play : Pieced Works On Paper., Gweneth A. Dunleavy 1954-

Electronic Theses and Dissertations

This thesis explores pattern juxtaposition using traditional American quilt block designs as the compositional basis for nine works pieced from screen printed paper. In the 1970s, the quilt was celebrated for its apparent connection to Modernist design and was reclaimed by many feminist artists including Miriam Schapiro as a symbol of the exclusion of women's crafts from the arts hierarchy. The tension between these two perspectives continues today in the contemporary art quilt movement. Block designs are tightly organized, relying on grids and repeated geometric forms to communicate multiple patterns simultaneously. Controlled placement of light and dark pieces can create …

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Priest, Prophet, Pilgrim : Types And Distortions Of Spiritual Vocation In The Fiction Of Wendell Berry And Cormac Mccarthy., Todd Edmondson May 2011

Priest, Prophet, Pilgrim : Types And Distortions Of Spiritual Vocation In The Fiction Of Wendell Berry And Cormac Mccarthy., Todd Edmondson

Electronic Theses and Dissertations

This dissertation provides a reading of characters in the novels and short stories of two important contemporary American writers through the lens of spiritual theology. While spirituality has often been understood as necessitating a flight from the particular, the concrete, or the everyday, theologians such as Rowan Williams and Nicholas Lash have presented a more robust version of spirituality that understands the call to spirituality not as an invitation to flee from this world, but rather a vocation to a way of life that seeks reconciliation within this world, encountering and embracing God's presence within the contexts of such realities …

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Reconciliation Of Il-1ss Loss With Trif-Biased Tlr4 Signaling By Monophosphate Lipid A., Chelsea A. Embry May 2011

Reconciliation Of Il-1ss Loss With Trif-Biased Tlr4 Signaling By Monophosphate Lipid A., Chelsea A. Embry

Electronic Theses and Dissertations

Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased pattern of TLR4 signaling, resulting in reduced production of MyD88-dependent pro-inflammatory factors, and credited TRIF-bias for MPLA's reduced toxicity. A contemporary study showed that MPLA fails to promote maturation of the potent inflammatory cytokine IL-1ß. This dissertation seeks to reconcile MPLA's TRIF-biased signaling with IL-1 ß loss, and to determine the ultimate cause of MPLA's reduced toxicity compared to LPS. We find that …

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Teenage Pharmapocalypse? : An Exploratory Examination Of Prescription Drug Abuse., Lorin Brooke Friley May 2011

Teenage Pharmapocalypse? : An Exploratory Examination Of Prescription Drug Abuse., Lorin Brooke Friley

Electronic Theses and Dissertations

The purpose of this study was to examine the phenomenon of teenage prescription drug abuse in Jefferson County, Kentucky to gain a better understanding of the environment and characteristics of a teenager who abuses prescription drugs, and to gain insight into this situation through the perspectives of adult professionals who regularly work with teenagers. In-depth interviews were conducted with five professionals, and data analyses were performed to determine recurring themes. There were four primary emergent themes, including: profiling of a teenage prescription drug abuser; factors influencing likelihood of drug abuse; portfolio of mental, emotional, and social issues; and treatment processes. …

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Delinquency : A Trajectory Analysis Of African-American Males., Wyatt Brown 1985- May 2011

Delinquency : A Trajectory Analysis Of African-American Males., Wyatt Brown 1985-

Electronic Theses and Dissertations

The initial goals of this study include locating and identifying the taxonomic groups mentioned in Moffitt's (1993) (i.e. life-course persistent offenders, adolescent-limited offenders) using data from the National Longitudinal Survey 1997 (NLSY97). Further, this study compares the social demographics with the predictions of Moffitt (1993,1994) as her theory describes race, particularity those of African-American offenders. This study also examines the role of parental and peer relationships and their effect on the offender disparity among the typologies defined by Moffitt (1993). This study explores one hypothesis: there is a relationship between social bonds, particularly peer association and admittance into Moffitt's (1993) …

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The Lived Experience Of Mothering During Incarceration., Barbara M. Jackson May 2011

The Lived Experience Of Mothering During Incarceration., Barbara M. Jackson

Electronic Theses and Dissertations

A phenomenological study of the lived experience of mothering during incarceration was conducted at a women's multi-custody level prison in Kentucky. The purpose of the study was to explore and describe the experience of mothering among incarcerated women to address the gap within this body of literature. Semi-structured interviews, observation, and field notes from 24 participants were collected and analyzed to provide an in-depth understanding of the mothering experience for the participants. Burnard's method was used for analysis of the interview data. Two major themes emerged including: Living in the fire: The lived experience of incarcerated mothers which stemmed from …

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Invisible Woman : A Case Study On Black Women's Experiences In Graduate Degree Programs In Central Kentucky., Ciara Nicole Pierce May 2011

Invisible Woman : A Case Study On Black Women's Experiences In Graduate Degree Programs In Central Kentucky., Ciara Nicole Pierce

Electronic Theses and Dissertations

Using black feminist perspective and standpoint this study explored factors that affect black women's matriculation and retention in graduate degree programs by examining how experiences and opportunities connected to race, class, and gender inform their decision to pursue and persist through graduate education. Specifically the study sought to investigate how the outlined factors affect the decision to pursue and matriculate through a graduate degree program. Those factors include: (1) educational preparedness, aspirations, and attitudes; (2) economic opportunities and restraints; (3) family obligations and expectations; (4) networks and mentoring; (5) and perceptions of usefulness. Data was collected by way of qualitative …

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Sound Image And Organic Form In Höller's "Regen-Kanon" (Sphären, Iv)., Adriana Guzman 1977- May 2011

Sound Image And Organic Form In Höller's "Regen-Kanon" (Sphären, Iv)., Adriana Guzman 1977-

Electronic Theses and Dissertations

"Regen-Kanon" is the fourth of six pieces or "sound images" in the orchestral cycle Spharen, composed by York Holler between 2001 and 2006. The first four movements, namely "Wolkengesang" ("Song of the Clouds"), "Windspiel" ("Wind Chimes"), "Erdschichten" ("Layers of Earth"), and "Regen-Kanon" ("Rain Canon") are related to Holler's experiences of particular landscapes and consequently to associated impressions of nature, whereas the fifth and sixth movements, "Feuerwerk" ("Fireworks") and "Spharentrauer" ("Sorrow of the Spheres") convey different kinds of images. Holler cites the influence of the philosophers Empedocles, Henri Bergson, and Peter Sloterdijk on his musical language and on Spharen in particular. …

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Mixed-Effects Models For Modeling Cardiac Functions And Treatment Effects., Hyejeong Jang May 2011

Mixed-Effects Models For Modeling Cardiac Functions And Treatment Effects., Hyejeong Jang

Electronic Theses and Dissertations

Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all available data can be used in mixed-effects model provided data are missing at random. For this reason, we focus on applying mixed-effects models to the repeated measurements of cardiac function including heart rate, left ventricle developed pressure, and coronary flow in the Glutathione-S-transferase P (GSTP) gene knockout and wild-type mice following ischemial/reperfusion injury performed in the isolated, Langendorff-perfused heart. Cardiac function is measured …

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Fluid Dynamic Analysis Of Flow In Orbiting Dishes And The Effects Of Flow On Shear Stress And Endothelial Cellular Responses., Amlan Chakraborty 1976- May 2011

Fluid Dynamic Analysis Of Flow In Orbiting Dishes And The Effects Of Flow On Shear Stress And Endothelial Cellular Responses., Amlan Chakraborty 1976-

Electronic Theses and Dissertations

This work presents a novel comprehensive effort to understand the fluid dynamics within orbiting dishes and the effects of the resulting oscillating fluid flow on shear and endothelial cellular responses within the dishes. It is well documented that hemodynamic parameters, especially wall shear stress (WSS), have been shown to play important roles in altering various endothelial cellular responses, intracellular pathways and gene expression, and to have significant impacts on disease progression, such as atherosclerotic plaque development. In practice, wall shear stress (WSS) is oscillatory rather than steady due to the travelling waveform and varies across the surface of the dish …

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Survey Of Pediatric Residents Regarding Communication Disorders And Augmentative And Alternative Communication., Karen J. Coulter May 2011

Survey Of Pediatric Residents Regarding Communication Disorders And Augmentative And Alternative Communication., Karen J. Coulter

Electronic Theses and Dissertations

Children with general communication impairments as well as complex communication needs rely on pediatricians to prescribe the services of speech language pathologists. In light of this continuing and increasing need, it is important to ascertain whether medical residents are receiving the necessary training in their educational program to fulfill their role. We need to understand how pediatric residents perceive their current level of abilities particularly within the framework of the current ACGME competencies. The purpose of this dissertation was to identify possible differences across pediatric resident levels regarding competence within three constructs, Medical Education, Medical Knowledge and Professional Practice, with …

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The Collective Affiliation Of Community College, Commuter And Distance Education Students : Developmental Math And Dropout., Jeffrey Cody Davidson May 2011

The Collective Affiliation Of Community College, Commuter And Distance Education Students : Developmental Math And Dropout., Jeffrey Cody Davidson

Electronic Theses and Dissertations

From 1988 to 2006, between 40% and 60% of all first-time community college students are referred to and enroll in at least one developmental education course; some colleges reported as high as 80 percent (e.g. Attewell, Lavin, Domina, & Levey, 2006; Bers & Smith, 1991; Bettinger & Long, 2005; Boughan & Clagett, 1995; Brawer, 1996). More students begin college less prepared in math than any other developmental area (e.g. ACT, 2006, 2007, 2008, 2009; Attewell, Lavin, Domina, & Levey, 2006; Bettinger & Long, 2005; Cartnal, 1999). The purpose of this quantitative study was to examine the relationship between a set …

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High Dynamic Range Imaging For The Detection Of Motion., Jeffrey Robert Hay May 2011

High Dynamic Range Imaging For The Detection Of Motion., Jeffrey Robert Hay

Electronic Theses and Dissertations

High dynamic range imaging involves imaging at a bit depth higher than the typical 8-12 bits offered by standard video equipment. We propose a method of imaging a scene at high dynamic range, 14+ bits, to detect motion correlated with changes in the measured optical signal. Features within a scene, namely edges, can be tracked through a time sequence and produce a modulation in light levels associated with the edge moving across a region being sampled by the detector. The modulation in the signal is analyzed and a model is proposed that allows for an absolute measurement of the displacement …

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How Collaborative The Collaboration? : Assessing The Collaboration Of Services For Juvenile Offenders., James G. Dickerson May 2011

How Collaborative The Collaboration? : Assessing The Collaboration Of Services For Juvenile Offenders., James G. Dickerson

Electronic Theses and Dissertations

Juvenile delinquency with co-occurring substance abuse and mental health disorders has become an increasing problem within the United States. In part this can be attributed to the excessive number of delinquent youth entering the juvenile justice system with untreated substance abuse and/or mental health disorders-thus requiring juvenile justice to become a default system for substance abuse and mental health intervention and treatment services. In an effort to combat this problem, governmental, mental health, social support agencies, and school systems have formed interagency collaborations to provide more effective treatment services. One such interagency collaboration is the JETS Program, a court diversion …

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Holy Horror: A Quantitative Analysis Of The Use Of Religion In The Yearly Top Grossing Horror Films From 2000 To 2009, Jason Duane Wheeler May 2011

Holy Horror: A Quantitative Analysis Of The Use Of Religion In The Yearly Top Grossing Horror Films From 2000 To 2009, Jason Duane Wheeler

Masters Theses

The yearly top-grossing films from 2000 to 2009 were analyzed to see if correlation exists between overt religious content and box office success. Also, the films were analyzed to see if correlation exists between overt religious content and IMDb.com user ratings. Neither box office success nor IMDb.com user ratings were found to be correlated with over religious content.

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Pioneer, Popularizer And Politician: John Clark Ridpath As A Public Intellectual, Tyler Archer May 2011

Pioneer, Popularizer And Politician: John Clark Ridpath As A Public Intellectual, Tyler Archer

Student Research

On May 28, 1894, John Clark Ridpath wrote Indiana University Professor James Woodburn and described the effort he had expended to complete his most recent historical volumes. “I have just returned from a long absence in New York,” he wrote, “where I have been detained for eighteen months with the publication of my work on the Great Races of Mankind. More recently, I have been in the Bermudas, whither I went in early April, on account of a little break in my health, following quite illogically the completion of a task to which I have devoted five and a half …

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Pathway Semantics: An Algebraic Data Driven Algorithm To Generate Hypotheses About Molecular Patterns Underlying Disease Progression, Mary Frances Mcguire May 2011

Pathway Semantics: An Algebraic Data Driven Algorithm To Generate Hypotheses About Molecular Patterns Underlying Disease Progression, Mary Frances Mcguire

Dissertations and Theses (Open Access)

The overarching goal of the Pathway Semantics Algorithm (PSA) is to improve the in silico identification of clinically useful hypotheses about molecular patterns in disease progression. By framing biomedical questions within a variety of matrix representations, PSA has the flexibility to analyze combined quantitative and qualitative data over a wide range of stratifications. The resulting hypothetical answers can then move to in vitro and in vivo verification, research assay optimization, clinical validation, and commercialization. Herein PSA is shown to generate novel hypotheses about the significant biological pathways in two disease domains: shock / trauma and hemophilia A, and validated experimentally …

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Analysis Of Band 4.1b In Integrin-Mediated Cell Adhesion And Signaling, Youngsin Jung May 2011

Analysis Of Band 4.1b In Integrin-Mediated Cell Adhesion And Signaling, Youngsin Jung

Dissertations and Theses (Open Access)

Band 4.1B is a cytoskeletal adaptor protein that regulates various cellular behavior; however, the mechanisms by which Band 4.1B contributes to intracellular signaling are unclear. This project addresses in vivo and in vitro functions for Band 4.1B in integrin-mediated cell adhesion and signaling. Band 4.1B has been shown to bind to β8 integrin, although cooperative functions of these two proteins have not been determined. Here, functional links between β8 integrin and Band 4.1B were investigated using gene knockout strategies. Ablation of β8 integrin and Band 4.1B genes resulted in impaired cardiac morphogenesis, leading to embryonic lethality by E11.5. These embryos …

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Investigation Of Facet Joint Capsule Biomechanics Of The Lumbar Spine: A Finite Element Study, Denis Charles Evangelista May 2011

Investigation Of Facet Joint Capsule Biomechanics Of The Lumbar Spine: A Finite Element Study, Denis Charles Evangelista

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Low back pain is one of the most costly ailments in the world today. A key biological structure studied in the research of low back pain is the facet joint. The facet joint is thought to both play a role in the causation of low back pain through its response to noxious loading and in its relief through beneficial loading caused by spine manipulation. The purpose of these studies is to use a computational model to predict the biomechanical response of the facet joints to various loading parameters. This was accomplished using a linear 3D Finite Element model of the …

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The Study Of Xpg Domains That Regulate The Late Steps Of Nucleotide Excision Repair, Adebanke Fagbemi May 2011

The Study Of Xpg Domains That Regulate The Late Steps Of Nucleotide Excision Repair, Adebanke Fagbemi

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The human nucleotide excision repair (NER) pathway resolves a range of lesions in DNA including those caused by harmful UV light, environmental mutagens, and agents of chemotherapy. The pathway involves the concerted action of over 30 proteins that recognize the damage, excise it within an oligonucleotide, and fill in the resulting gap, restoring the DNA to its original form. The importance of NER is evident in impaired patients who suffer from a range of diseases with symptoms such as high predisposition to skin cancer, extreme sensitivity to sunlight, and neurological and developmental abnormalities. While the early steps in NER involving …

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Practical Reasoning With Transaction Logic Programming For Knowledge Base Dynamics, Paul Fodor May 2011

Practical Reasoning With Transaction Logic Programming For Knowledge Base Dynamics, Paul Fodor

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Transaction Logic is an extension of classical predicate calculus for representing declarative and procedural knowledge in logic programming, databases, and artificial intelligence. Since it provides a logical foundation for the phenomenon of state changes, it has been successful in areas as diverse as workflows, planning, reasoning about actions, Web services, security policies, active databases and more. Although a number of implementations of Transaction Logic exist, none is logically complete due to the time and space complexity of such implementations. In the first part of this thesis, we describe an approach for performing actions in the logic, which has better complexity …

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Computational Systems Analysis Of Deterministic Pair Rule Gene Network And Stochastic Bicoid Morphogen Gradient In Drosophila Melanogaster, Yu Feng Wu May 2011

Computational Systems Analysis Of Deterministic Pair Rule Gene Network And Stochastic Bicoid Morphogen Gradient In Drosophila Melanogaster, Yu Feng Wu

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Computational systems biology is an emerging field built upon advances in biological experimentation, computational tools, and joint interdisciplinary efforts from physical sciences to engineering. In this thesis, I solve two important problems in the developmental genetics of Drosophila melanogaster by means of two different computational systems approaches, one stochastic and the other deterministic. In the first problem I use exact simulations of a spatially extended Master Equation to analyze intrinsic fluctuations in the gradient of the Bicoid morphogen. These simulation results were in turn compared to quantitative experimental measurements of Bicoid levels performed in fixed tissue by immunostaining. We selected …

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The Effects Of Elevated Carbon Dioxide Concentrations On The Early Life History Of Bivalve Shellfish, Stephanie Carol Talmage May 2011

The Effects Of Elevated Carbon Dioxide Concentrations On The Early Life History Of Bivalve Shellfish, Stephanie Carol Talmage

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The combustion of fossil fuels has increased CO2 in the world's oceans and decreased pH. Ocean acidification may alter the growth, survival, and diversity of marine organisms that synthesize shells due to decreased carbonate ion availability. I examined the response of larvae and early juveniles from three species of commercially and ecologically valuable bivalve shellfish (Mercenaria mercenaria, Argopecten irradians, and Crassostrea virginica) exposed to past, pre-industrial levels (~250 ppm), present (~390 ppm), and future (~750, 1500 ppm) levels of CO2. Under higher CO2 concentrations, all three species experienced decreased growth, survival, and metamorphosis with C. virginica being the least affected. …

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The Role Of Beta-1 Integrin In Oligodendrocyte Development And Cns Myelination., Tom Thanh Van Nguyen May 2011

The Role Of Beta-1 Integrin In Oligodendrocyte Development And Cns Myelination., Tom Thanh Van Nguyen

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Myelin is essential for proper human neurophysiology, but the precise molecular mechanisms underlying the myelination process remain poorly understood. One potential effector molecule, the b1 integrin, has been suggested to play a critical role in CNS myelination. In support of this, a6b1 integrin has been shown to modulate oligodendrocyte development in vitro and the loss of an integrin ligand, laminin, causes myelin defects in vivo. Here, we use transgenic mice (b1-CNSko) engineered to excise the b1 integrin gene at the neural progenitor stage to study how b1 integrin modulates oligodendrocyte development and myelination. Electron micrographs of the spinal cord and …

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On The Fringe Of Notch: Mapping O-Fucose And O-Glucose Glycans At Specific Sites On The Extracellular Domains Of Notch Receptors Using Nano-Lc-Esi-Ms/Ms, Nadiaa. Rana May 2011

On The Fringe Of Notch: Mapping O-Fucose And O-Glucose Glycans At Specific Sites On The Extracellular Domains Of Notch Receptors Using Nano-Lc-Esi-Ms/Ms, Nadiaa. Rana

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Notch is an essential cell surface receptor whose proper functioning is critical during development in metazoans. Notch can be modified with two unique forms of O-linked glycosylation: O-fucose and O-glucose. Protein O-fucosyltransferase1 (Pofut1, OFUT1 in flies) and Protein O-glucosyltransferase (Poglut, Rumi in flies) are the glycosyltransferases that add O-fucose and O-glucose monosaccharides to Notch, respectively. Loss of Pofut1/Ofut1 or Poglut/rumi in mice or flies phenocopies Notch-null phenotypes, suggesting both forms of O-glycosylation are essential for Notch function. To gain insights into how these essential modifications impart functionality to the receptor, it is vital to identify sites of O-glycosylation, and structures …

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Power Analysis Of The Likelihood Ratio Test For Logistic Regression Mixtures, Minyoung Lee May 2011

Power Analysis Of The Likelihood Ratio Test For Logistic Regression Mixtures, Minyoung Lee

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Finite mixture models emerge in many applications, particularly in biology, psychology and genetics. This dissertation focused on detecting associations between a quantitative explanatory variable and a dichotomous response variable in a situation where the population consists of a mixture. That is, there is a fraction of the population for whom there is an association between the quantitative predictor and the response and there is a fraction of individuals for whom there is no association between the quantitative predictor and the response. We developed the Likelihood Ratio Test (LRT) in the context of ordinary logistic regression models and logistic regression mixture …

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Simulation Of Unexploded Ordnance Identification Using Tagged-Neutron Interrogation And Neural Networks, Xiaohai Zhu May 2011

Simulation Of Unexploded Ordnance Identification Using Tagged-Neutron Interrogation And Neural Networks, Xiaohai Zhu

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

This research is a collaboration between the Department of Mechanical Engineering at Stony Brook University and the Department of Environmental Sciences at Brookhaven National Laboratory. It is proposed to use 14 MeV neutrons tagged by the associated particle neutron time-of-flight technique (APnTOF) to identify the fillers of unexploded ordnances (UXO). The ultimate goal is to construct a prototype portable neutron interrogation probe that will search for UXO in a target volume, locate targets in three dimensions, and accurately identify the major elemental constituents. To facilitate the design of a prototype system, a preliminary simulation model was developed, using the Geant4 …

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Moment Propagation Methods For Stochastic Simulation Of Complex Biochemical Systems, Vibha Mane May 2011

Moment Propagation Methods For Stochastic Simulation Of Complex Biochemical Systems, Vibha Mane

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

We are interested in predicting the time dependent behavior of biochemical networks such as interaction between proteins. These networks are represented by a system of chemical reactions. In the forward problem, we have knowledge of all the reactions and the associated rate constants. We want to determine the joint probability density of the populations of all the molecular species at any time instant. The given biochemical system is a discrete state, continuous time Markov process, and the time evolution of its probability density function is described by the chemical master equation (CME). We want to obtain the solution of the …

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