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Ozark Highland Cunaxidae (Acari: Prostigmata): Descriptions And Keys To Genera Found To Occur In The Region And A New Phylogenetic Hypothesis For The Family, Michael Joseph Skvarla

Graduate Theses and Dissertations

Fourteen genera of Cunaxidae (Acari: Prostigmata) are reported from the Ozark Highlands for the first time. Descriptions, diagnoses, and illustrated keys to genera and world species are given. Five new species are described and illustrated and an additional 6 known species are recorded from the region. The first rigorous phylogenetic hypothesis for Cunaxidae is presented. Based on morphology, it suggests the current subfamilial classification scheme does not reflect the evolutionary history of the family. Unfortunately, bootstrap values and resolution are low, suggesting the need for further indepth molecular analyses.

Stability And Sensory Properties Of Rice Bran Peptide Fraction Incorporated Orange Juice, Mirna Georges Khairallah

Graduate Theses and Dissertations

Functional foods offer consumers added benefits beyond the sole nutritional content of the food. Food companies are aggressively seeking new and cheaper sources of functional ingredients. Kannan et al. (2008) characterized anticancer peptides and peptide fraction from rice bran. However, information about their application and stability in food is lacking. In this study the stability of the peptide fraction in water at pH 7.2, at pH 3.5, and in orange juice was studied. The effect of the addition of the peptide fraction on the quality parameters of orange juice including sensory was also assessed. The results showed that the peptide …

Protein Kinase Cδ And C-Abl Kinase Are Required For Transforming Growth Factor Β Induction Of Endothelial-Mesenchymal Transition In Vitro., Zhaodong Li, Sergio A. Jimenez

Department of Medicine Faculty Papers

OBJECTIVE: The origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through transdifferentiation of endothelial cells (ECs) into myofibroblasts via endothelial-mesenchymal transition (EndoMT) in vitro and to explore the signaling pathways involved in this process.

METHODS: Primary mouse pulmonary ECs isolated by immunomagnetic methods with sequential anti-CD34 and anti-CD102 antibody selection were cultured in monolayers. Cell morphology and diacetylated low-density lipoprotein uptake assays confirmed their EC characteristics. The induction of EndoMT was assessed by determination of α-smooth …

Incorporating Case Studies Into An Undergraduate Genetics Course, Marlene Murray

Faculty Publications

Genetics is considered one of the most challenging courses in the biology curricula at both the secondary and post secondary levels. Case based teaching has been shown to improve student perception and performance outcomes in both non-science and science courses. Thus in an effort to improve outcomes, case studies were integrated into an undergraduate genetics course as a supplement to lecture and replacement to recitation. Student perception and performance when case studies were used was compared to two previous years before the incorporation of case studies. Student course evaluations, pre and post surveys of student knowledge, and exam scores indicated …

Iron Limitation Of A Springtime Bacterial And Phytoplankton Community In The Ross Sea: Implications For Vitamin B12 Nutrition, Erin M. Bertrand, Mak A. Saito, Peter A. Lee, Robert B. Dunbar, Peter N. Sedwick, Giacomo R. Ditullio

OES Faculty Publications

The Ross Sea is home to some of the largest phytoplankton blooms in the Southern Ocean. Primary production in this system has previously been shown to be iron limited in the summer and periodically iron and vitamin B-12 colimited. In this study, we examined trace metal limitation of biological activity in the Ross Sea in the austral spring and considered possible implications for vitamin B-12 nutrition. Bottle incubation experiments demonstrated that iron limited phytoplankton growth in the austral spring while B-12, cobalt, and zinc did not. This is the first demonstration of iron limitation in a Phaeocystis antarctica-dominated, early …

Assessing The Influence Of Hemlock Mortality On Streams Due To Hemlock Woolly Adelgid Infestation, Celestine Che

All Theses

For the past 30 years eastern hemlock forests in the US have been declining rapidly due to damage caused by a destructive exotic insect pest, the hemlock woolly adelgid, Adelges tsugae Annand (Homoptera: Adelgidae), a native of the Far East. The impact of the loss of hemlocks, which occur naturally in cool hillside and ravine environments along streams, is poorly understood. The loss of these trees has the potential to cause significant environmental disturbance by changing energy inputs into streams, stream microclimates, and aquatic macroinvertebrate communities.
In May 2009, after hemlock mortality due to A. tsugae was already severe, I …

Analysis Of Dna Methylation Differerences Between High And Low Chill Peach (Prunus Persica [L. Batsch]), Sherri Hughes-Murphree

All Theses

Chilling requirement is a critically important phenological trait that controls the timing of vegetative bud break and floral bloom, and impacts the climatic distribution of temperate tree species. However, the molecular basis of the chilling requirement trait is not well understood. Analysis of chilling requirement QTL from peach and apricot has detected numerous genes known to modulate DNA and histone methylation pathways. Evidence from other plant systems suggests these types of epigenetic mechanisms may play a role in temperature-modulated plant developmental responses.
For this study, DNA from vegetative buds of overwintering peach trees was examined for changes in methylation status …

Nr1l: A Novel Nuclear Receptor Group Activated By Juvenile Hormone Analogs, Yangchun Li

All Theses

Annotation of the Daphnia pulex nuclear receptors revealed a novel group of three receptors designated NR1L, and named HR97a/b/g because of their similarity to the HR96 receptors involved in xenobiotic detection. We cloned and sequenced the three receptors from a related species often used in aquatic toxicology studies, Daphnia magna, and then analyzed their genomic structure and conducted phylogenetic studies. Phylogenetic studies confirmed that the HR97s do form a distinct group with HR97g being the precursor of HR97a and b. They also confirmed that the HR97 receptors are related to the HR96 (NR1J) receptors, and the VDR/CAR/PXR (NR1I) group. Mining …

Retrofit Solutions For Sealed Pervious Concrete Pavements, Gregory Bunting

All Theses

The goal of this research was to design, implement, and evaluate several retrofit solutions for sealed pervious concrete. Properly functioning pervious concrete pavements allow water to drain through the structure, eliminating the need for traditional drainage infrastructure. A recent study of South Carolina porous pavements (Putman 2010) revealed that some pervious concrete pavements are not properly draining, either because of sealing at the surface. Sealed pavements are generally a result of construction processes, and sealed pavements cannot be fixed with sediment removal techniques such as vacuuming and pressure washing. This study investigates a technique to increase infiltration of sealed pervious …

Going All The Way: Phylogeography And Trans-Pacific Divergence Genetics Of Nucella Lima, Lisa Cox

All Theses

Fluctuating climate over the last 2 million years (MY) has repeatedly caused latitudinal shifts in species distributions, fueling the hypothesis that the glacial-interglacial dynamics of the Pleistocene could have driven regional genetic differentiation and potentially speciation. For species whose distributions spanned the entire North Pacific, regional extinction of northern populations during cooler glacial periods may have resulted in isolation and genetic differentiation of eastern and western populations. To test this hypothesis, I gathered genetic data from a rocky shore intertidal gastropod, Nucella lima, whose current (i.e. warm interglacial) distribution spans the entire North Pacific. Mitochondrial DNA sequences are genetically structured …

Changes In Expression Of Akt Pathway Proteins Following Treatment With Rg3 In Vitro, Kathryn Schalkoff

All Theses

To assess changes in AKT pathway signaling, a recombinant protein of the G3 domain of rat laminin-5 (rG3) that specifically binds the alpha subunit of integrins α6β1 and α6β4 expressed on cancer cells (e.g., MDA-MB-231) was produced. This recombinant protein is believed to interrupt the intracellular signaling events of the AKT pathway, causing a decrease in proliferation and survival of cells after treatment. Viability assays confirmed an apoptotic effect of rG3 on cells in a dose-dependent manner. However, data from gene expression studies of Caspase-9, GRB10, and CDKNIB proved non-conclusive that rG3 is acting upon gene expression, leading to the …

Role Of Belowground Fungal Mutualisms And Nutrient Cycling Alteration In Invasion Success Of Polygonum Cuspidatum Sieb. & Zucc. (Polygonaceae) In The Eastern United States, Gretchen Addington

All Theses

Plant species invasion is problematic around the world due to its negative effects on native plant biodiversity, ecosystem function, and ecosystem stability. Understanding the mechanisms of plant species invasion is necessary to predict new invasions and to control current problematic species. Polygonum cuspidatum Sieb. & Zucc. (Polygonaceae, Japanese Knotweed) is an invasive species found in 40 of the 50 United States and listed as a noxious species in nine states. It is known to exclude native plant communities, and its eradication is nearly impossible. The extensive negative effects associated with this species make understanding its mechanism of invasion a prerogative. …

Sediment Based Turbidity Analyses For Representative South Carolina Soils, Katherine Resler

All Theses

Construction activities have been recognized to have significant impacts on the environment. Excess sediment from construction sites is frequently deposited into nearby surface waters, negatively altering the chemical, physical and biological properties of the water body. This environmental concern has led to strict laws concerning erosion and sediment control, such as imposing permit conditions that limit the concentration of suspended solids that can be present in effluent water from construction sites. However, sediment concentration measurements are not routinely used to detect and correct short-term problems or permit violations because laboratory analysis of sediment concentrations is time-consuming and costly. Nevertheless, timely, …

Substrate Topography Design And Fabrication For Osteoblast And Dental Pulp Stem Cells Studies, Gloria Chen

All Theses

Research for cell guidance based tissue engineering has rapidly grown due to the increasing interest in tissue engineering and reconstructive medicine applications, such as cranial reconstruction. Many research teams have begun the process of identifying what factors influence cell behavior (including cell growth, proliferation, alignment and spreading). Published studies have pointed to the influence of the cell medial pH, substrate stiffness, chemistry and topography. Conclusive results are often hard to identify since researchers often vary many of these factors simultaneously and it is hard to decouple individual factor influence. These reports also points out that the cellular response can be …

Heterogeneity, Control, Social Infrastructure, And Possibilities Of Participation: Their Interplay In Modern Understandings Of Heredity And In Interpretation Of Science, Peter J. Taylor

Working Papers on Science in a Changing World

This working paper is a prospectus for research, writing, and engagement. It consists of vignettes, sketches of lines of inquiry, and proposals for engagement, all of which concern modern understandings of heredity and development over the life course as well as the social interpretation of science. The various items address a range of areas of science and of its interpretation: heritability studies, the social uses of genetic information, gene-by-environment interaction, personalized medicine, IQ paradoxes, racial group membership, biobanks, and life events and difficulties research. Fresh perspectives in these areas are opened up by examining the ways that research and application …

Technical Assistance For The Revision Of The Conservation Agreement For The Spring Mountains National Recreation Area: Final Closeout Report, Public Lands Institute

Public Lands Institute Publications

Technical Assistance for the revision of the Conservation Agreement for the Spring Mountains National Recreation Area was cooperative agreement between the U.S. Fish and Wildlife Service (USFWS) and the Board of Regents of the Nevada System of Higher Education. The cooperator was the Public Lands Institute (PLI) of the University of Nevada, Las Vegas (UNLV) working directly with staff of the USFWS Southern Nevada Field Office and the U.S. Forest Service’s (USFS) Humboldt-Toiyabe National Forest. The mechanism of cooperation was a Cooperative Ecosystem Studies Unit (CESU) Task Agreement. The purpose of the project was to provide technical assistance to the …

Proceedings Of The Ii International Meeting In Exercise Physiology

International Journal of Exercise Science: Conference Proceedings

Proceedings of the II International Meeting in Exercise Physiology. Meeting held May 5-7, 2011. This meeting was promoted by the Exercise Physiology Laboratory / UFSCar, in collaboration with UNICAMP and UNIMEP universities. The event was designed to bring Brazilian scientists, especially from São Paulo state that work with Exercise Physiology and Health. The main objective was to put together these students and scientists interested in developing joint researches in this area.

2011 Summer Commencement, Harding University

Commencement Programs

Program for the Commencement on July 30.

Commencement Speaker: Milton R. Sewell

Does Physical Activity Influence Semantic Memory Activation In Amnestic Mild Cognitive Impairment?, J. Carson Smith, Kristy A. Nielson, John L. Woodard, Michael Seidenberg, Matthew D. Verber, Sally Durgerian, Piero Antuono, Alissa M. Butts, Nathan C. Hantke, Melissa A. Lancaster, Stephen M. Rao

Psychology Faculty Research and Publications

The effect of physical activity (PA) on functional brain activation for semantic memory in amnestic mild cognitive impairment (aMCI) was examined using event-related functional magnetic resonance imaging during fame discrimination. Significantly greater semantic memory activation occurred in the left caudate of High- versus Low-PA patients, (P=0.03), suggesting PA may enhance memory-related caudate activation in aMCI.

A Mathematician Weighs In On The Evolution Debate, Kris H. Green

Journal of Humanistic Mathematics

There are a variety of reasons underlying the lack of public acceptance for the theory of evolution in the United States. An overlooked cause is related to problems with the mathematics curriculum in the K-12 setting. In this essay, we examine this relationship and propose changes to the mathematics curriculum that could improve mathematical thinking while also providing a basis for understanding theories, like evolution, that are poorly understood.

Rumors Of Our Rarity Are Greatly Exaggerated: Bad Statistics About Women In Science, Cathy Kessel

Journal of Humanistic Mathematics

During the past few years, three bad statistics have been persistently used in discussions of women in science, technology, engineering, and mathematics (STEM). The first was questionable when it was published in 1983 and has since been widely used. The second came to prominence in 2006 – and now leads an international and perhaps eternal life on the Web. The third may have made its debut in 2007. Its variants occur in popular and academic books and journals, including the 2011 Proceedings of the National Academy of Sciences.

This report presents case histories of the three bad statistics, suggests writing …

Growing Out Of Adolescence: Conceptions Of Adulthood, Close Relationships, And Health Behaviors Of Emerging Adults With Hiv, Olivia Hsin

Open Access Dissertations

Objective: The current study examined conceptions of adulthood, close personal relationships, and health behaviors (dietary intake, substance use, sexual behaviors) of emerging adults aged 18-30 with horizontally-infected HIV. Emerging adults were expected to differ in levels of achievement of adulthood tasks. The quality of close relationships, and perceptions of close friends’ behaviors were hypothesized to be associated with health behaviors. Method: Utilizing a cross-sectional design, 48 emerging adults with HIV (64.6% female; M age = 22.59, SD = 3.17) from a youth-based clinic serving most of Miami-Dade County were recruited. Participants completed measures on markers of adulthood, close friend and …

Communication Deviance, Expressed Emotion, And Family Cohesion In Schizophrenia, Radha G. Carlson

Open Access Dissertations

Although schizophrenia is a biologically-based disorder, environmental stress (including stress within familial relationships) plays a major role in the onset and maintenance of symptoms. This study examined family variables that have implications for psychotherapeutic treatment of schizophrenia. Previous research has found Communication Deviance (CD), Expressed Emotion (EE), and family cohesion (FC) to be related to symptom severity. However, the exact nature of the relationship between these constructs is unclear. The current study tested a model whereby the tone and content of family member’s communication (EE) and the sense of family unity (FC) are hypothesized to mediate the relationship between CD …

Uab Scientist Hopes Plant Work Translates To Humans, Jim Bakken

Browse All News

No abstract provided.

Cistronic Stop Signal Ratio Of Mitochondrial Genes Suggests Multiple Waves Of Human Migrations In And Out Of Africa, Naby Yaya Sankhon

Electronic Theses and Dissertations Archive

The mitochondrial Cistronic Stop Signal Ratios (CSSR) is defined as a series of 12 numerals representing the ratio of TAA, TAG, AGG, and AGA nucleotide trimmers. Primate mitochondria use these nucleotide trimmers as stop codons and many of these trimmers are also found on the 2nd and 3rd reading frames of a cistron. We showed that the average value of the CSSR of all the 13 protein coding genes in mitochondria (genomic CSSR) could be used to define the phylogenetic relationship between the primates. However, the genic CSSR of most human mitochondria are essentially identical, except for the CSSR of …

Synergistic Combination Of Hyperoxygenation And Radiotherapy By Repeated Assessments Of Tumor Po2 With Epr Oximetry, Huagang Hou, Ruhong Dong, Jean P. Lariviere, Sriram P. Mupparaju, Harold M. Swartz, Nadeem Khan

Dartmouth Scholarship

The effect of hyperoxygenation with carbogen (95% O₂ + 5% CO₂) inhalation on RIF-1 tumor pO₂and its consequence on growth inhibition with fractionated radiotherapy is reported. The temporal changes in the tumor pO₂ were assessed by in vivo Electron Paramagnetic Resonance (EPR) oximetry in mice breathing 30% O₂ or carbogen and the tumors were irradiated with 4 Gy/day for 5 consecutive days; a protocol that emulates the clinical application of carbogen. The RIF-1 tumors were hypoxic with a tissue pO₂ of 5–9 mmHg. Carbogen (CB) breathing significantly increased tumor pO₂, …

Graduate Commencement, Philadelphia (2011), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus Graduate Program Commencement program, Class of 2011. Degrees include Doctor of Psychology in Clinical Psychology, Doctor of Psychology in School Psychology, Educational Specialist in School Psychology, Master of Science in School Psychology, Master of Science in Counseling and Clinical Health Psychology, Master of Science in Organizational Development and Leadership, Master of Science in Forensic Medicine, Master of Science in Biomedical Sciences, and Master of Science in Health Sciences – Physician Assistant Studies.

Protection And Attachment Of Vibrio Cholerae Mediated By The Toxin-Coregulated Pilus In The Infant Mouse Model, Shelly J. Krebs, Ronald K. Taylor

Dartmouth Scholarship

Colonization of the human small intestine by Vibrio cholerae is an essential step in pathogenesis that requires the type IV toxin-coregulated pilus (TCP). To date, three functions of TCP have been characterized: it serves as the CTXΦ receptor, secretes the colonization factor TcpF, and functions in microcolony formation by mediating bacterium-bacterium interactions. Although type IV pili in other pathogenic bacteria have been characterized as playing a major role in attachment to epithelial cells, there are very few studies to suggest that TCP acts as an attachment factor. Taking this into consideration, we investigated the function of TCP in attachment to …

Transcriptome Analysis Of Epithelial And Stromal Contributions To Mammogenesis In Three Week Prepartum Cows., Theresa Casey, Heather Dover, James Liesman, Lindsey Devries, Matti Kiupel, Michael Vandehaar, Karen Plaut

Department of Animal Sciences Faculty Publications

Transcriptome analysis of bovine mammary development has provided insight into regulation of mammogenesis. However, previous studies primarily examined expression of epithelial and stromal tissues combined, and consequently did not account for tissue specific contribution to mammary development. Our objective was to identify differences in gene expression in epithelial and intralobular stromal compartments. Tissue was biopsied from non-lactating dairy cows 3 weeks prepartum, cut into explants and incubated for 2 hr with insulin and hydrocortisone. Epithelial and intralobular stromal tissues were isolated with laser capture microdissection. Global gene expression was measured with Bovine Affymetrix GeneChips, and data were preprocessed using RMA …

Evolution Of Trefoil Factor(S): Genetic And Spatio-Temporal Expression Of Trefoil Factor 2 In The Chicken (Gallus Gallus Domesticus)., Zhengyu Jiang, Amy C. Lossie, Todd J. Applegate

Department of Animal Sciences Faculty Publications

Trefoil factors are essential healing initiators participating in mucosal reconstitution and tissue morphogenesis, especially on the surfaces of the gastrointestinal tract. This family has been cloned and characterized predominantly from mammals and amphibians. Avian species ingest stone and grit to help digest food, which may expose their gut to severe physical conditions. To further the understanding of the function of the TFF gene family across species, we undertook this research to clone, sequence, and characterize the spatio-temporal expression patterns of chicken TFF2 (ChTFF2) cDNA. Bioinformatics analysis of the promoter region and deduced amino acid sequence demonstrated that ChTFF2 …