Digital Commons Network^™

Neuroendocrine Function Of Female Youth With Callous-Unemotional Traits, Andrew Gostisha

LSU New Orleans Theses and Dissertations

Callous-unemotional (CU) traits have been shown to designate a particular subgroup of antisocial youth that are particularly violent, recidivistic, and more likely to continue offending in adulthood. Disordered neuroendocrine function may be a mechanism for the development of CU traits. We examined whether altered stress responsivity served as a mechanism linking stress exposure and the expression of CU traits. Participants were 15 incarcerated adolescent girls with CU traits. Measures of CU traits, stress exposure, and salivary cortisol were collected. Results revealed girls with CU traits had higher morning levels of cortisol, an intact cortisol awakening response (CAR), and flatter diurnal …

Dark Consciousness: Theory Of Mind And Henry James’S The Golden Bowl, Adam Maillet

LSU New Orleans Theses and Dissertations

Using the psychological concepts of Theory of Mind and embodied cognition, the author explores and questions the traditional readings of Henry James's novel, The Golden Bowl, and its protagonist, Maggie Verver. Although the majority of critics view her as a positive character, James takes great effort to subvert her thoughts and mislead the reader. Despite lacking a modern technical vocabulary, James remains acutely aware of how human cognitive structures both process a text and function within a social setting.

Metabolism And Cryo-Sensitivity Of Domestic Cat (Felis Catus) And Cheetah (Acinonyx Jubatus) Spermatozoa, Kimberly Terrell

LSU New Orleans Theses and Dissertations

Teratospermia (ejaculation of ≥ 60% structurally abnormal spermatozoa) is prevalent among felids facing extinction risk, including the cheetah. This trait also occurs in certain domestic cat populations, providing a valuable research model. Multiple components of sperm function are disrupted in teratospermic cats, and even structurally normal spermatozoa from these ejaculates may be functionally compromised. Teratospermic ejaculates are highly sensitive to damage during cryopreservation, limiting the success of genome resource banking programs for species conservation. Although both teratospermia and cryopreservation are linked to disruptions in multiple energy-dependent sperm processes, the metabolism of these cells has not been investigated. This project explored …

Ferritin Diversity: Mechanistic Studies, Disease Implications, And Materials Chemistry, Robert Joseph Hilton

Theses and Dissertations

The study of ferritin includes a rich history of discoveries and scientific progress. Initially, the composition of ferritin was determined. Soon, it was shown that ferritin is a spherical, hollow protein. Eventually, over several decades of research, the structure and some function of this interesting protein was elucidated. However, the ferritin field was not completely satisfied. Today, for example, researchers are interested in refining the details of ferritin function, in discovering the role of ferritin in a variety of diseases, and in using ferritin for materials chemistry applications. The work presented in this dissertation highlights the progress that we have …

Water In Protein Cavities: Free Energy, Entropy, Enthalpy, And Its Influences On Protein Structure And Flexibility, Hongtao Yu

LSU New Orleans Theses and Dissertations

Complexes of the antibiotics novobiocin and clorobiocin with DNA gyrase are illustrative of the importance of bound water to binding thermodynamics. Mutants resistantto novobiocin as well as those with a decreased affinity for novobiocin over clorobiocinboth involve a less favorable entropy of binding, which more than compensates for amore favorable enthalpy, and additional water molecules at the proteinligandinterface.Free energy, enthalpy, and entropy for these water molecules were calculated by thermodynamicintegration computer simulations. The calculations show that addition of thewater molecules is entropically unfavorable, with values that are comparable to the measuredentropy differences. The free energies and entropies correlate with the …

Synthesis Of Chiral Intermediates By Deritivization Of Monosaccharides, Sanjeeva Dodlapati

LSU New Orleans Theses and Dissertations

Conformationally constrained bicyclic amino acids are invaluable in the synthesis of natural products and peptidomimetics. Aeruginosins contain novel bicyclic amino acid, 2--‐carboxy--‐6--‐hydroxyl octahydrindole (Choi) as the core structure. Aeruginosins are tetra peptide serine protease inhibitors isolated from marine sponges and cyanobacterial water blooms. Rigid bicyclic amino acid(Choi)is an essential core structure, which strongly influences biological activity of aeruginosin family members. Aeruginosins showed promising inhibitory activity against thrombin, trypsin, and factor VIIa. Thrombin and factor VIIa play a major role in blood clotting cascade; excessive coagulation leads to thrombosis and other cardiovascular diseases. Several research groups have reported a number of …

Sea: A Novel Computational And Gui Software Pipeline For Detecting Activated Biological Sub-Pathways, Thair Judeh

LSU New Orleans Theses and Dissertations

With the ever increasing amount of high-throughput molecular profile data, biologists need versatile tools to enable them to quickly and succinctly analyze their data. Furthermore, pathway databases have grown increasingly robust with the KEGG database at the forefront. Previous tools have color-coded the genes on different pathways using differential expression analysis. Unfortunately, they do not adequately capture the relationships of the genes amongst one another. Structure Enrichment Analysis (SEA) thus seeks to take biological analysis to the next level. SEA accomplishes this goal by highlighting for users the sub-pathways of a biological pathways that best correspond to their molecular profile …

Characterization Of The Desorption Electrospray Ionization Mechanism Using Microscopic Imaging Of The Sample Surface, Michael Craig Wood

Theses and Dissertations

Desorption electrospray ionization (DESI) is an ambient ionization technique for mass spectrometry. This solvent based desorption ion source has wide applicability in surface analysis with minimal sample preparation. Interest in improving detection limits, broadening applications, and increasing the spatial resolution for chemical imaging has led to studies of the DESI mechanism. An inverted microscope has been used to image interactions between the DESI spray and test analytes on a glass surface. Microscopic images recorded with millisecond time resolution have provided important insights into the processes governing analyte transport and desorption. These insights are the basis of a rivulet-based model for …

Creating Online Tutorials At Your Libraries: Software Choices And Practical Implications, Maribeth Slebodnik, Catherine Fraser Riehle

Libraries Faculty and Staff Scholarship and Research

No abstract provided.

Mosaicism For Trisomy21: Utility Of Array-Based Technology For Its Detection And Its Influence On Telomere Length And The Frequency Of Acquired Chromosome Abnormalities, Chariyawan Charalsawadi

Theses and Dissertations

The primary aim of this study was to determine the effectiveness of array-based technology for detecting and quantifying the presence of mosaicism. This aim was achieved by studying individuals having mosaicism for Down syndrome. SNP arrays were performed on 13 samples from individuals with mosaicism for trisomy 21, 13 samples from individuals with normal chromosome 21complements (negative controls) and 5 samples from individuals with full or partial trisomy 21 (positive controls). In addition, BAC arrays were processed on 6 samples from individuals with mosaicism for trisomy 21, 3 negative controls and 1 positive control. These studies have shown that array-based …

Distributed Graduate Seminars: An Interdisciplinary Approach To Studying Land Conservation, Jessica Owley, Adena R. Rissman

Pace Environmental Law Review Online Companion

No abstract provided.

Teaching From The Dirt: Best Practices And Land Use Law Pedagogy, Keith H. Hirokawa

Pace Environmental Law Review Online Companion

No abstract provided.

Now We're Cooking!: Adding Practical Application To The Recipe For Teaching Sustainability, Jonathan Rosenbloom

Pace Environmental Law Review Online Companion

This essay explores the benefits and challenges presented by incorporating experiential learning into the Drake University Law School course, Sustainability & Its Application. The course combined academic inquiry with actual, practical experience to facilitate student professional development, enhance practice skills, and explore a new and rapidly developing area of law concerning sustainability. This essay provides the core details of the course, and hopefully serves as a guideline for similar courses.

Understanding The Origin And Rapid Diversification Of The Genus Anthurium Schott (Araceae), Integrating Molecular Phylogenetics, Morphology And Fossils, Monica Maria Carlsen

Dissertations

Anthurium is a strictly neotropical genus of Araceae ranging from southern Mexico to northern Argentina, including ca. 900 species and displaying an enormous variation in leaf morphology, growth habit, leaf venation pattern and inflorescence and fruit colors. Despite its immense diversity, its ecological importance in Neotropical forests, and a very long history of botanical collection, cultivation, and taxonomical research, Anthurium had been almost neglected in molecular phylogenies. This study combines chloroplast (trnG intron, trnH-psbA and trnC-ycf6 intergenic spacers) and nuclear (CHS first intron) DNA sequence data for 102 Anthurium species and uses maximum parsimony, likelihood and Bayesian phylogenetic analysis to …

2011 August 3 -- Agenda And Attachments

Agendas and Minutes

No abstract provided.

Minutes, 2011 August 3

Agendas and Minutes

No abstract provided.

Multiple Testing Of Local Maxima For Detection Of Peaks In Chip-Seq Data, Armin Schwartzman, Andrew Jaffe, Yulia Gavrilov, Clifford A. Meyer

Harvard University Biostatistics Working Paper Series

No abstract provided.

We Are...Marshall, August 3, 2011, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Deafdigest: Mid-Week Edition, August 3, 2011, Barry Strassler

DeafDigest Mid-Week 2011

No abstract provided.

August 3, 2011 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.

Spinal Reconstruction With Pedicle Screw-Based Instrumentation And Rhbmp-2 In Patients With Neurofibromatosis And Severe Dural Ectasia And Spinal Deformity: Report Of Two Cases And A Review Of The Literature, Samuel K. Cho, Geoffrey E. Stoker, Keith H. Bridwell

Open Access Publications

No abstract provided.

Volume 48, Number 50: August 03, 2011, University Of North Dakota

University Letter Archive

No abstract provided.

The Daily Gamecock, Wednesday, August 3, 2011, University Of South Carolina, Office Of Student Media

August

No abstract provided.

Senior Elise Porcher Receives Sda Award Of Excellence, University Relations

Campus News Archive

The art student's fiber art piece was accepted for the juried Confluence: 2011 International Surface Design Association Student Members’ Exhibition.

Reference Database Usage Statistics 2010-2011, Michael A. Cerbo Ii, Sarah Bannister

Technical Services Reports and Statistics

Statistics on the use of online reference databases at the University of Rhode Island during the period from July 2010 through June 2011. Includes COUNTER-compliant data on sessions, searches, turnaways, full text articles downloaded, cost per search, and other metrics.

Carotid Plaque Regression Following 6-Month Statin Therapy Assessed By 3t Cardiovascular Magnetic Resonance: Comparison With Ultrasound Intima Media Thickness, Raymond Q. Migrino, Mark Bowers, Leanne Harmann, Robert W. Prost, John F. Ladisa

Biomedical Engineering Faculty Research and Publications

Background

Cardiovascular magnetic resonance (CMR) allows volumetric carotid plaque measurement that has advantage over 2-dimensional ultrasound (US) intima-media thickness (IMT) in evaluating treatment response. We tested the hypothesis that 6-month statin treatment in patients with carotid plaque will lead to plaque regression when measured by 3 Tesla CMR but not by IMT.

Methods

Twenty-six subjects (67 ± 2 years, 7 females) with known carotid plaque (> 1.1 mm) and coronary or cerebrovascular atherosclerotic disease underwent 3T CMR (T1, T2, proton density and time of flight sequences) and US at baseline and following 6 months of statin therapy (6 had initiation, …

Utilizing Induced Voxel Correlation In Fmri Analysis, Daniel B. Rowe, Andrew S. Nencka

Mathematics, Statistics and Computer Science Faculty Research and Publications

No abstract provided.

Educational Attainment: Success To The Successful, Peter John Anthony, David Gould, Gina Smith

Higher Learning Research Communications

Systems archetypes are patterns of structure found in systems that are helpful in understanding some of the dynamics within them. The intent of this study was to examine educational attainment data using the success-to-the-successful archetype as a model to see if it helps to explain the inequality observed in the data. Data covering 1990 to 2009 was collected from the United States Census Bureau for the United States, as well as for the States of Georgia and Washington. Findings indicated that this archetype is useful in explaining the variation, and there are several other terms and concepts that are helpful …

The Characterization Of Avian Polyomavirus, Satellite Tobacco Mosaic Virus, And Bacteriophage Cw02 By Means Of Cryogenic Electron Microscopy, Peter S. Shen

Theses and Dissertations

Viruses are the most abundant biological entity in the biosphere and are known to infect hosts from all domains of life. The aim of my work is to identify conserved and non-conserved features among the capsid structures of related and divergent icosahedral viruses via cryogenic electron microscopy, sequence analysis, molecular modeling, and other techniques. Bird polyomaviruses often cause severe disease in their hosts whereas mammalian polyomaviruses generally do not. Avian polyomavirus is a type of bird polyomavirus with an unusually broad host range compared to the restricted tropism of other polyomaviruses. Although most polyomaviruses have a conserved, rigid capsid protein …

Benefits Of Physical Activity On Depression And Functional Quality Of Life During Treatment For Breast Cancer: Psychosocial Mechanisms., Jamie M. Stagl

Open Access Theses

Women who are post surgery for breast cancer (BCa) experience distressing side effects that negatively influence Quality of Life (QoL). Physical activity (PA) following a BCa diagnosis is associated with decreased mortality, reduced recurrence, increased functional capacity, less fatigue, and may improve depression and QoL. Furthermore, evidence suggests that a combined PA and psychotherapy intervention may reduce physically and emotionally distressing side effects associated with diagnosis and treatment. The purpose of the study is to examine relationships among PA, fatigue, clinician-rated depression, depressed mood, and QoL in women after undergoing surgery for BCa and to assess the continuity of these …