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2011

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Friction And Leakage Characteristics Of Inflatable Structures In Tunnels, Joshua J. Sill Jan 2011

Friction And Leakage Characteristics Of Inflatable Structures In Tunnels, Joshua J. Sill

Graduate Theses, Dissertations, and Problem Reports (ETD)

Inflatable technology has become a popular alternative for replacing conventional ways of building structures. Inflatable structures offer the benefits of being lightweight and portable while maintaining needed rigidity and reducing production costs. These benefits have prompted the use of inflatables in confined spaces such as pipes and tunnels to act as barriers with minimal infrastructure modification. This work focuses on using these inflatables, or plugs, in transportation subway tunnels as a way to mitigate threats such as floods.;In order to stop the flow of water, the plug must be capable of being pressurized and apply enough pressure on the tunnel …


Demographic Response Of American Ginseng (Panax Quinquefolius L.) To Climate Change, Sara Souther Jan 2011

Demographic Response Of American Ginseng (Panax Quinquefolius L.) To Climate Change, Sara Souther

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ecological response to recent climate change has been documented for a multitude of species worldwide. Climate models predict further increases in temperature, as much as 8 times the degree of warming that has already occurred. Given observations of species response to contemporary climate change and the unprecedented degree of warming expected over the next century, climate change will no doubt determine future ecosystem composition and affect global species diversity. In order to prevent loss of biodiversity, it is necessary to understand and accurately project species' response to climate, and to identify species that are vulnerable to climate change driven extinctions. …


Molecular Phylogeny Of The Oestroidea, Baneshwar Singh Jan 2011

Molecular Phylogeny Of The Oestroidea, Baneshwar Singh

Graduate Theses, Dissertations, and Problem Reports (ETD)

The superfamily Oestroidea includes approximately 9% (≈14,000 spp.) of the order Diptera. Many members of the superfamily are of medical, veterinary, agricultural, and forensic importance. Although Oestroidea has been the subject of much scientific scrutiny, the exact patterns of phylogenetic relationships among the key groups of the superfamily are unresolved and controversial. For a better understanding of oestroid evolutionary hypotheses, phylogenies of Oestroidea were reconstructed at several taxonomic levels using DNA sequence data. The specific aims were to determine the phylogeny of the 1) genus Chrysomya (Chrysomyinae); 2) subfamily Chrysomyinae (Calliphoridae); 3) family Oestridae (Oestroidea); and 4) family Calliphoridae (Oestroidea). …


Comparison Of Parent-Child Interactions In Abusive And Control Families: An Observational Study, Jocelyn F. O. Stokes Jan 2011

Comparison Of Parent-Child Interactions In Abusive And Control Families: An Observational Study, Jocelyn F. O. Stokes

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study sought to identify differences in caregiver-child interactions between caregivers with and without prior reports of child physical abuse. Data for the abuse group were made available for secondary analyses by the National Archive for Child Abuse and Neglect via Cornell University. Data for the comparison group were collected for a previous study at West Virginia University. For both studies, caregiver-child dyads participated in a 5---minute, videotaped observation in a situation in which the parent had to exert moderate control over the child. Data that had been coded using the Dyadic Parent---Child Interaction Coding System (Eyberg, et al., 1994; …


Emotional Pain And Acute Nociception, Alison M. Vargovich Jan 2011

Emotional Pain And Acute Nociception, Alison M. Vargovich

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined differences and similarities in responses to acute nociception in adults with a significant history of emotional pain relative to matched controls with a significant past positive life experience and a sample of chronic pain patients. Using 28 volunteers who responded to advertisements (n = 14, emotional pain group; n = 14, positive life experience group), and 14 chronic pain patients from a prior study, this investigation utilized measures of pain threshold and tolerance during a laboratory finger pressure pain induction experiment. Each participant experienced two levels of pressure pain (i.e., high and low) and two levels of …


Computational Hybrid Systems For Identifying Prognostic Gene Markers Of Lung Cancer, Ying-Wooi Wan Jan 2011

Computational Hybrid Systems For Identifying Prognostic Gene Markers Of Lung Cancer, Ying-Wooi Wan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lung cancer is the most fatal cancer around the world. Current lung cancer prognosis and treatment is based on tumor stage population statistics and could not reliably assess the risk for developing recurrence in individual patients. Biomarkers enable treatment options to be tailored to individual patients based on their tumor molecular characteristics. To date, there is no clinically applied molecular prognostic model for lung cancer. Statistics and feature selection methods identify gene candidates by ranking the association between gene expression and disease outcome, but do not account for the interactions among genes. Computational network methods could model interactions, but have …


Development Of An Emotional Pain Interview, Ben Weinstein Jan 2011

Development Of An Emotional Pain Interview, Ben Weinstein

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study developed and tested the Emotional Pain Interview (EPI), a semi-structured interview measuring emotional pain, using community dwelling adults with a significant history of emotional pain (n = 16; emotional pain group) relative to matched controls reporting a prior significant positive life experience (n = 16; positive life experience group). The EPI and a matching positive life event interview were used to assess all participants regarding prior emotionally painful and positive life experiences. Participants completed measures of anxiety sensitivity, depression, and posttraumatic stress disorder. Ratings of emotional responding (i.e., Valence, Arousal, and Control/Dominance) were made for prior emotionally painful …


Formulating A Conceptual Framework To Understand Native American Perceptions Of Place And Identity: A Temporal Examination Of The Spatio-Social Effects Of Uneven Development Through Accumulation By Dispossession, Denyse Wyskup Jan 2011

Formulating A Conceptual Framework To Understand Native American Perceptions Of Place And Identity: A Temporal Examination Of The Spatio-Social Effects Of Uneven Development Through Accumulation By Dispossession, Denyse Wyskup

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research dialectically conceptualizes how capitalist uneven development and subsequent occurrences has shaped, and continues to shape, Native American perceptions of place and identity. Specifically, this research focuses on accumulation by dispossession, a key component of uneven development, and the spatio-historic effects this form of dispossession has had on Native American lifeworlds. This research focuses primarily upon federal legislation in the form of treaties, acts, and court rulings as the predominant component sustaining accumulation by dispossession and, in turn, perpetuating uneven development within Native American communities. In order to more holistically conceptualize the impacts of accumulation by dispossession three Native …


De Novo Asymmetric Syntheses Of Bioactive Natural Products And Carbohydrate Motifs, Yalan Xing Jan 2011

De Novo Asymmetric Syntheses Of Bioactive Natural Products And Carbohydrate Motifs, Yalan Xing

Graduate Theses, Dissertations, and Problem Reports (ETD)

De novo asymmetric syntheses of daumone I-1 and the fluorescent analog have been described. This route took advantage of the Noyori asymmetric hydrogenation of acetyl furan and alkynyl ketone, the Pd-catalyzed glycosylation and various post-glycosylation transformations to finish the total synthesis of Daumone I-1, which provided materials for mechanism of action studies.;In an effort to mimics natures use of rare sugars in the synthesis of biologically important natural products (e.g., the carbohydrate portion of Daumone I-1), the O'Doherty group has been interested in developing new methods for practical and stereoselective synthesis. As part of these efforts, a concise synthesis of …


Protein Surface Characterization Using An Invariant Descriptor, Zainab Abu Deeb Jan 2011

Protein Surface Characterization Using An Invariant Descriptor, Zainab Abu Deeb

Graduate Theses, Dissertations, and Problem Reports (ETD)

A novel descriptor to characterize protein surfaces, and hence classify functionally similar proteins into functional families is proposed. The descriptor exploits the protein tertiary structure surface, locally and globally, to identify intra-family proteins. By using only sparse data based on the C-alpha atoms on the protein surface, we characterize the surface using different invariant descriptors, namely, distance distributions, residue co-occurrences, and distance-residue co-occurrences between all atoms confined to a particular patch. Using the method, proteins with very low sequence similarity were successfully classified into their functional families with a high degree of accuracy.


The Effects Of Expertise And Demographic Characteristics On Public Administrators' Attitudes To E-Government, Raji Msail Alsharari Jan 2011

The Effects Of Expertise And Demographic Characteristics On Public Administrators' Attitudes To E-Government, Raji Msail Alsharari

Graduate Theses, Dissertations, and Problem Reports (ETD)

Due to recent advancements in electronic technology (e-technology), research on the developing field has become important for understanding how this technology affects the population and how the population affects this technology. Research on e-technology reveals that demographic characteristics (age, gender, location, and education) and expertise are factors affecting e-technology attitudes and performance. One of the emerging e-technology fields is electronic government (e-government). After reviewing historical research in e-technology, this study reviewed existing e-government literature to determine key obstacles for public administrators to implement e-government. This study used a survey questionnaire, based on e-government attitude surveys conducted by Moon (2002) and …


An Epidemiological Assessment Of Lung Function Decline As A Predictor Of Morbidity And Mortality, Penelope J. Baughman Jan 2011

An Epidemiological Assessment Of Lung Function Decline As A Predictor Of Morbidity And Mortality, Penelope J. Baughman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Excessive lung function decline is associated with increased risks of respiratory morbidity and mortality outcomes including chronic obstructive pulmonary disease (COPD). COPD is a disease afflicting approximately 80 million people worldwide and as of 2002, the fifth leading cause of death. COPD is an increasing problem, with substantial increases projected in COPD deaths if there is no reduction of the causal risk factors. By 2030, COPD is projected to be the third leading cause of death worldwide, an increase mainly due to extended life expectancies and that COPD deaths occur at older ages. COPD is also largely underdiagnosed, partially due …


Parameterized Strings: Algorithms And Data Structures, Richard A. Beal Jan 2011

Parameterized Strings: Algorithms And Data Structures, Richard A. Beal

Graduate Theses, Dissertations, and Problem Reports (ETD)

A parameterized string (p-string) T = T[1] T[2]...T[n] is a sophisticated string of length n composed of symbols from a constant alphabet Sigma and a parameter alphabet pi. Given a pair of p-strings S and T, the parameterized pattern matching (p-match) problem is to verify whether the individual constant symbols match and whether there exists a bijection between the parameter symbols of S and T. If the two conditions are met, S is said to be a p-match of T. A significant breakthrough in the p-match area is the prev encoding, which is proven to identify a p-match between S …


Immune System Based Control And Intelligent Agent Design For Power System Applications, Rabie Belkacemi Jan 2011

Immune System Based Control And Intelligent Agent Design For Power System Applications, Rabie Belkacemi

Graduate Theses, Dissertations, and Problem Reports (ETD)

The National Academy of Engineering has selected the US Electric Power Grid as the supreme engineering achievement of the 20th century. Yet, this same grid is struggling to keep up with the increasing demand for electricity, its quality and cost. A growing recognition of the need to modernize the grid to meet future challenges has found articulation in the vision of a Smart Grid in using new control strategies that are intelligent, distributed, and adaptive. The objective of this work is to develop smart control systems inspired from the biological Human Immune System to better manage the power grid at …


Temporal Changes In Soil Carbon Concentration And Quality In A Reclaimed Minesoil Chronosequence, Sriroop Chaudhuri Jan 2011

Temporal Changes In Soil Carbon Concentration And Quality In A Reclaimed Minesoil Chronosequence, Sriroop Chaudhuri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Atmospheric carbon dioxide (CO2) concentrations have increased significantly over the last half century causing erratic changes in global climate and the ecological balance of the earth. With proper land management practices, reclaimed minesoils can act as CO2- sinks, thus contributing to the terrestrial carbon sequestration efforts to mitigate effects of increased atmospheric CO2 concentrations. The objective of this research was to determine temporal changes in soil organic carbon (SOC) geochemistry and contents in a reclaimed minesoil chronosequence. The study area comprised four reclaimed minesoils in Monongalia County, West Virginia, with time since reclamation ranging between 2 to 21 years. A …


New Methodologies For In Vitro Analysis Of Binding And Functional Activity Of Sigma Receptor Ligands, James A. Fishback Jan 2011

New Methodologies For In Vitro Analysis Of Binding And Functional Activity Of Sigma Receptor Ligands, James A. Fishback

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sigma receptors represent a promising drug development target for a number of therapeutic indications including cancer, depression, psychostimulant abuse and stroke. To date, two subtypes of sigma receptors have been identified; sigma1 and sigma2. Their respective roles in normal physiology and in disease processes are a subject of ongoing studies. Consequently, the discovery and development of subtype specific agonist and antagonist ligands remains a key research goal. To date, no in vitro functional assay suitable for routine screening of putative sigma ligands has been reported. As a result, radioligand binding assays are used as a primary screen. Therefore, to support …


Mechano-Enzymatic Pretreatment Of Lignocellulosic Biomass, Bibu Philip George Jan 2011

Mechano-Enzymatic Pretreatment Of Lignocellulosic Biomass, Bibu Philip George

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recalcitrance of lignocellulosic cell wall is a major hurdle that needs to be disrupted for biochemical refinery to be successful. Pretreatment of lignocellulosic materials play a key role for the conversion of lignocellulosic feed stocks to fermentable sugars. At present, various pretreatment technologies mainly achieved by empirical methods are available for the production of sugars from lignocellulosic polysaccharides. These methods depend largely upon the "demolition" of the cell wall by strong chemicals or using high energy input. As a result, these processes release "smaller compounds" as by-products or end products which inhibits downstream fermentation of monomeric sugars.;This project is a …


Expression Of The Cytosolic Phospholipase A2 Isozymes In The Human Breast Cancer Cell Line Models Mda-Mb 231 And Mcf-7 And The Normal Breast Cell Line Model Mcf-10a, Debolina Ganguly Jan 2011

Expression Of The Cytosolic Phospholipase A2 Isozymes In The Human Breast Cancer Cell Line Models Mda-Mb 231 And Mcf-7 And The Normal Breast Cell Line Model Mcf-10a, Debolina Ganguly

Graduate Theses, Dissertations, and Problem Reports (ETD)

Breast cancer remains one of the leading causes of cancer related death among women worldwide. Numerous reports have provided evidence of a role of inflammation in the onset and progression of many cancers, including breast cancer. A mechanism that leads to inflammation involves the arachidonic acid (AA) pathway, which leads to the production of a group of pro-inflammatory bioactive lipids, collectively known as the eicosanoids. Despite evidence of AA and the eicosanoids in cancer, limited work has been done on the enzyme cytosolic phospholipase A2 (cPLA2) that provides the unesterified AA that can be used for eicosanoid generation. The present …


Diet Induced Alterations And Distribution Of Indices Of Lysine Catabolism, Stephanie K. Gatrell Jan 2011

Diet Induced Alterations And Distribution Of Indices Of Lysine Catabolism, Stephanie K. Gatrell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lysine is thought to be oxidized primarily by lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are restricted to the mitochondrial matrix. Lysine is presumably transported through the plasma membrane by isoforms(s) of a cationic amino acid transporter (CAT). Although the mechanism(s) of lysine transport through the inner mitochondrial membrane is not known, it is presumptively transported by one or both mitochondrial "ornithine transporters" (ORC-1/ORC-2). Tissue distribution of LKR and the mechanism(s) responsible for alterations in hepatic lysine catabolism in swine are unclear. Also, the roles of the alternative pathways of lysine degradation, the L-amino acid oxidase-dependent (LAAO), in …


Feeding Behavior Of Podisus Maculiventris (Say) (Hemiptera: Pentatomidae): Implications For Mass Rearing And Biological Control, Sudan Gyawaly Jan 2011

Feeding Behavior Of Podisus Maculiventris (Say) (Hemiptera: Pentatomidae): Implications For Mass Rearing And Biological Control, Sudan Gyawaly

Graduate Theses, Dissertations, and Problem Reports (ETD)

Spined soldier bug, Podisus maculiventris (Say) (Hemiptera: Pentatomidae), is a generalist predator feeding on more than 70 different insect species. P. maculiventris is noted for its potential for augmentative release against coleopteran and lepidopteran larvae. Successful mass rearing and determination of potential prey of a biological control agent are crucial factors that need consideration for success of a biological control agent in augmentative biological control. Firstly, study was conducted to investigate feeding behavior of P. maculiventris using yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae). Using different life stages of T. molitor that P. maculiventris could potentially feed on in mass rearing …


Modeling Of Roughness And Dissipation Of Actuated Polymer Films, Joaquin Maria Gutierrez Jan 2011

Modeling Of Roughness And Dissipation Of Actuated Polymer Films, Joaquin Maria Gutierrez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Actuated polymer films (APF) are a novel kind of material with several possible applications (e.g., dynamic roughness for aerodynamic flow control, tactile responsive touch panels, dust mitigation systems for solar panels and other devices, and tunable hydrophobicity surfaces). The development of the required analytical and numerical tools for the design and analysis of APF's is addressed in this research.;A hyperelastic hysteretic material model (Bergstrom-Boyce) is used to model the APF. A program to calibrate the Bergstrom-Boyce material parameters from experimental data is developed using MATLABRTM. The soundness of this calibration tool is assessed using experimental data from the literature.;To calculate …


Intelligent Reservoir Modeling Of Lower Huron Shale, Ognjen Grujic Jan 2011

Intelligent Reservoir Modeling Of Lower Huron Shale, Ognjen Grujic

Graduate Theses, Dissertations, and Problem Reports (ETD)

The work presented in this thesis is an intelligent reservoir modeling and analysis of Lower Huron Shale in eastern Kentucky. Methodology used for this analysis is a recently developed Top Down Intelligent Reservoir Modeling, that couples artificial intelligence and data mining techniques with conventional reservoir engineering methods. A total of 77 wells completed in Lower Huron Shale in eastern Kentucky were used in this study. Well production data was obtained from the company operating the wells, while completion reports and well logs were downloaded from publicly available database at Kentucky Geological Surveys website. The downloaded well logs were digitized, and …


Contraceptive Effect Of A Vaccine Targeting Leukemia Inhibitory Factor That Is Vital For Implantation, Angela Rae Lemons Jan 2011

Contraceptive Effect Of A Vaccine Targeting Leukemia Inhibitory Factor That Is Vital For Implantation, Angela Rae Lemons

Graduate Theses, Dissertations, and Problem Reports (ETD)

Immunomodulation at the fetal-maternal interface is essential for the establishment and maintenance of pregnancy. Several interleukins have been shown to be key in this process. Leukemia inhibitory factor (LIF), a member of the interleukin-6 family of proteins, is vital for blastocyst implantation in both humans and mice. LIF is expressed by the uterine epithelium and stromal cells surrounding the blastocyst prior to implantation and acts via binding to the LIF receptor expressed on the endometrium. This study investigates the contraceptive effect of a vaccine prepared with peptides derived from LIF and LIF receptor in the murine model. The vaccine was …


Understanding The Role Of Ascorbic Acid And Gdp-Mannose Pyrophosphorylase Affecting Ammonium Sensitivity, Genome Stability And Flowering Time In Arabidopsis Thaliana, Chase F. Kempinski Jan 2011

Understanding The Role Of Ascorbic Acid And Gdp-Mannose Pyrophosphorylase Affecting Ammonium Sensitivity, Genome Stability And Flowering Time In Arabidopsis Thaliana, Chase F. Kempinski

Graduate Theses, Dissertations, and Problem Reports (ETD)

L-ascorbic acid is an important antioxidant in both plants and animals. In plants, it is important for detoxifying reactive oxygen species that are produced during photosynthesis and cellular metabolism. It also contributes to several facets of plant growth as an enzyme cofactor, signaling molecule, and a precursor to several other metabolites. It has been implicated in the control of flowering time and senescence as well as several other growth processes largely through work with the ascorbic acid-deficient vtc mutants of Arabidopsis thaliana. Biochemical and genetic experiments have identified several pathways contributing to ascorbic acid biosynthesis, with the D-mannose/L-galactose pathway predominantly …


Metabolic Syndrome And Its Associations With Psychological Distress And Subclinical Cardiovascular Disease Among Police Officers, Tara Autumn Hartley Jan 2011

Metabolic Syndrome And Its Associations With Psychological Distress And Subclinical Cardiovascular Disease Among Police Officers, Tara Autumn Hartley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Police officers are a vital part of every community in the U.S. Officers are routinely exposed to numerous types of stressors, including traumatic events, shift work and organizational issues. The impact of this exposure can lead to chronic physical and psychological health problems. Police officers have been reported to have higher rates of cardiovascular disease (CVD). Previous studies have found associations between work stress and CVD, and this association may be mediated by the metabolic syndrome (MetSyn). MetSyn is a clustering of metabolic abnormalities, including abdominal obesity, hypertension, glucose intolerance and dyslipidemia, that has been associated with CVD and Type …


Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui Jan 2011

Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui

All ETDs from UAB

The unfolded protein response is one mechanism utilized by endoplasmic reticulum (ER) to maintain the homeostasis between ER protein folding machinery and ER proteins. UPR is induced by three ER transmembrane sensors: IRE1, ATF6 and PERK. PKR-like ER kinase (PERK) can sense the ER stress signal through its luminal domain to activate its cytoplasmic kinase domain catalytic activity. PERK kinase domain belongs to the eIF2α family. Members in this family are activated after being autophosphorylated at their activation loops and then specifically phosphorylate eIF2α at its Ser51 position. Phosphorylation of eIF2α can shutdown the cytosol protein translation from the initiation …


Osteogenic Differentiation Of Human Mesenchymal Stem Cells Enhanced By Bone Ecm Analogous Nanomatrix Composites, Jeremy Benton Vines Jan 2011

Osteogenic Differentiation Of Human Mesenchymal Stem Cells Enhanced By Bone Ecm Analogous Nanomatrix Composites, Jeremy Benton Vines

All ETDs from UAB

A growing trend in the area of bone tissue engineering is the development of materials that mimic the native bone extracellular matrix (ECM). This need is typically met through the creation of composites, which attempt to recapitulate both the organic and inorganic components of the native bone ECM. However, few composites have been created with organic ECM analogous components that are functionalized to direct cellular behaviors. Furthermore, a majority of these studies do not investigate how the ratio of the inorganic and organic components affects cellular behaviors. To address this issue, hydroxyapatite nanoparticles (HANPs) were dispersed within peptide amphiphile (PA) …


Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram Jan 2011

Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Successful treatment of breast cancer directly correlates with tumor stage and grade at diagnosis. Early diagnosis leads to a five-year relative survival rate of 96.8% as opposed to only a 22.5% five-year survival rate when diagnosed at late stage. Cancer-specific mechanisms need to be extended to enable cancer detection in an individual patient, in particular, the metastatic burden that currently cannot be assessed by conventional imaging. This approach for cancer detection would remove the biases of patient characteristics, permit immediate diagnostic feedback, improve sensitivity for early detection of small metastatic lesions, and be cost effective. Toward this goal, the cancer-specific …


Sustainable Urban Design Practices That Mitigate Urban Heat Islands And Reduce Energy Consumption, Candace Joy Watson Jan 2011

Sustainable Urban Design Practices That Mitigate Urban Heat Islands And Reduce Energy Consumption, Candace Joy Watson

All ETDs from UAB

Urban cities are the largest consumers of energy. As global populations continue to increase in these areas, energy consumption is a growing concern for global leaders. Cities in developed countries are expanding beyond their central city-centers, resulting in increased natural resource consumption. This method of population management is referred to as urban sprawl and is the reason for increased consumption from expanding transportation networks, building materials, and fuel resources. In addition to increases in energy consumption, in recent years, built-up areas have experienced higher temperatures than surrounding rural areas. According to the Environmental Protection Agency, these differences can be as …


Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White Jan 2011

Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

The virus Eastern Equine Encephalitis virus (EEEV) is a highly pathogenic arthropod-borne virus (arbovirus) present in the US. The virus is listed as a reportable illness to the Centers of Disease Control and Prevention (CDC) and is also listed as a select agent by Human Health and Services (HHS). Studies on EEEV starting back in the 1930's have determined many important facets of the ecology, transmission and evolution of the virus. It is understood that in many endemic foci, the mosquito Culiseta melanura is the primary enzootic vector of the virus. EEEV is thus maintained in an enzootic cycle between …