Digital Commons Network^™

Did The Fda Properly Assess The Safety Of Olestra As A Food Additive?, Leah Lebel

The Science Journal of the Lander College of Arts and Sciences

The following is an excerpt of the introduction to this article: Olestra, a fat-substitute comprised of sucrose that has been esterified with fatty acids (Blume 1995), has been the subject of much controversy ever since its creation. Olestra is not absorbed (Mattson and Nolen 1972) because it cannot be hydrolyzed by pancreatic lipases (Mattson and Volpenhein 1972) or taken up across the enterocyte microvillus membrane (Freston et al. 1997), and thus, cannot be utilized for energy. Olestra has physical and organoleptic properties similar to those of traditional triglycerides (Jandacek and Webb 1978) and is emulsified together with triglyceride (Freston et …

Alteplase: The Clot Buster, Mayer Goldberg

The Science Journal of the Lander College of Arts and Sciences

The following is an excerpt from the introduction of this article: The human body is defined by many complex and inconsistent characteristics. For example, the body forms blood clots in traumatic events, but blood clots are likewise associated with hazardous or fatal conditions. Platelets are small cells, derived from the precursor megakaryocytes, which are responsible for blood clotting to prevent bleeding from a ruptured blood vessel. Platelets fasten to each other and release a coagulation factor that solidifies around the ruptured area to prevent blood loss. A subordinate quantity of platelets can result in excessive bleeding. However, high platelet numbers …

Distribution And Properties Of Vesicular Horizons In The Western United States, Judith K. Turk, Robert C. Graham

Conservation and Survey Division: Faculty and Staff Publications

Vesicular horizons are thin (usuallycm) surface or near-surface horizons characterized by the predominance of vesicular porosity. Th ey are widespread in arid and semiarid lands, occurring on every continent and covering 156,000 km2 of the western United States. Vesicular horizons have critical implications for management due to their role in controlling surface hydrology and dust mobilization. Th is study evaluates the distribution and varia-tion in expression of vesicular horizons across the western United States using the soil databases available from the USDA. A vesicular horizon index (VHI) that incorporates vesicular horizon thickness and the size and quantity of vesicular pores …

Clinical And Functional Assessment Following Autologous Chondrocyte Implantation To The Knee: The Role Of Patient Reported Outcomes, Performance Based Assessment, And Response Shift, Jennifer Sebert Howard

Theses and Dissertations--Rehabilitation Sciences

Autologous chondrocyte implantation (ACI) is a cell based therapy for the treatment of articular cartilage defects. Numerous studies have reported outcomes following ACI using a variety of patient reported outcomes (PROs), but no clear recommendations exist regarding which PRO is the most responsive to changes following ACI. Few studies have documented changes in performance based assessments (PBAs) following ACI. Response shift theory proposes that residual changes in self-report measures occur over time. Failing to account for response shift may result in over or under reporting of outcomes from which clinical decisions are made. The purposes of this dissertation were 1) …

Acts-Hf: Attention, Cognition And Self-Care In Heart Failure, Catherine M. Murks

Dissertations

Background: Patients with heart failure (HF) are required to participate in self-care activities. This activities include taking prescribed medications, monitoring for symptoms, intervening appropriately and evaluating the response to the treatment. Cognitive impairment occurs relatively frequently in this population. Few studies have attempted to describe the nature of the relationship between self-care and cognitive impairment in this population.

Purpose:/ This study investigated the relationship between cognitive function and self-care ability in patients with HF. It also investigated the relationship between both self-care and cognitive function and subsequent hospital admission.

Methods:/ Participants were recruited from outpatient areas at two cardiology groups …

Supplementation With All Three Macular Carotenoids: Response, Stability, And Safety, Eithne Connolly, Stephen Beatty, James Loughman, Alan Howard, Michael Louw, John Nolan

Articles

Purpose This study was designed to investigate serum and macular response, and safety, to supplementation with meso-zeaxanthin (MZ), lutein (L) and zeaxanthin (Z), the carotenoids that constitute macular pigment (MP).

Materials and Methods 44 healthy subjects were recruited into this randomized, placebo-controlled, clinical trial. Subjects consumed one tablet per day containing 10.6 mg MZ, 5.9 mg L and 1.2 mg Z (Intervention, I group) or placebo (P group). The spatial profile of MP optical density (MPOD) was measured using heterochromatic flicker photometry (HFP), and serum concentrations of L and Z were quantified using high performance liquid chromatography (HPLC). Subjects …

Sage Collection, Ucf Libraries

Technology Fee Funded Projects

The UCF Libraries is requesting $124,450 to purchase the 2011 Sage Deep Backfile Collection. Sage Publications, Inc. is a respected academic publisher with strong content in business, humanities, social sciences, science, technology, and medicine. Sage journals, books, and electronic media are used by scholars, practitioners, researchers, and students. The UCF Libraries continues to pursue complete access to content from major academic publishers to meet current needs and to ensure long term access to the content. The Sage Deep Backfile Collection, with its strong humanities content, will complement the Complete Springer Archives, purchased with 2010 Technology Fee funding, which has a …

Legislative Control Of The Menhaden Fishery, Nicole M. Rovner, Matthew G. Curtis

Richmond Public Interest Law Review

This year, six menhaden- related bills were introduced in the Virginia General Assembly. Delegate John Cosgrove (RChesapeake) introduced legislation in the House of Delegates that was identical to Senate Bill 765, a bill that proposed to shift oversight of the menhaden fishery to the VMRC. This article aims to highlight the unique stance taken by Virginia's legislature and explain why this management is better left to the commission responsible for managing every other fishery in the Commonwealth. While there may not be a conclusive link between reduction industry practices and a decline in water quality, Virginia's legislators should recognize the …

Hidden Truth: The Perils And Protection Of Off-Label Drug And Medical Device Promotion, Gregory Conko

Health Matrix: The Journal of Law-Medicine

No abstract provided.

Preglimony, Shari Motro

Law Faculty Publications

Unmarried lovers who conceive are strangers in the eyes of the law. If the woman terminates the pregnancy, the man owes her nothing. If she takes the pregnancy to term, the man's obligation to support her is limited. The law reflects this lovers-as-strangers presumption by making a man's obligation towards a woman with whom he conceives derivative of his paternity-related obligations; his duty is towards his child, not towards the woman in her own right. Thus, a pregnant woman's lost wages and other personal costs are her private problem, and if there is no child at the end of the …

Strength Of The International Trade Commission As A Patent Venue, Christopher A. Cotropia

Law Faculty Publications

The data suggests that the ITC is here to stay and almost all patent enforcement actions will take place, at least in part, in the ITC. The landscape of patent enforcement has permanently changed, and the ITC is a solid part of it. This Article reaches these conclusions by first, in Part I, describing the unique features of the ITC that make it a favored venue of patentees. Part II describes the Federal Circuit's decision in Kyocera and the various postulates as to its impact. Part III describes the study, the specific data obtained, and the results. Part IV analyzes …

Sex Bias In Neuroscience And Biomedical Research, Annaliese K. Beery, Irving Zucker

Neuroscience: Faculty Publications

Female mammals have long been neglected in biomedical research. The NIH mandated enrollment of women in human clinical trials in 1993, but no similar initiatives exist to foster research on female animals. We reviewed sex bias in research on mammals in 10 biological fields for 2009 and their historical precedents. Male bias was evident in 8 disciplines and most prominent in neuroscience, with single-sex studies of male animals outnumbering those of females 5.5 to 1. In the past half-century, male bias in non-human studies has increased while declining in human studies. Studies of both sexes frequently fail to analyze results …

Synthesis, Self-Assembly And Biological Properties Of Self-Folding Cu(Ii) Coordination Polymers, Alejandro Arzola-Rubio

Open Access Theses & Dissertations

The synthesis of materials via molecular self-assembly is a powerful bottom-up approach for fabricating matter in the nano- and micro-meter scales. This methodology involves the spontaneous and reversible organization of small molecules that interact with one another to create larger structures driven by non-covalent interactions such as hydrogen bonding, hydrophobic forces and metal-ligand coordination interactions. In this thesis, the design, synthesis and characterization of a new set of molecules that spontaneously self-organize in water to form three-dimensional nanoscale toroidal structures was investigated. These supramolecular structures were designed with an intrinsic affinity to bind and condense DNA strands with the intent …

Accumulation, Speciation, And Distribution Of Metal(Loids) In Plants: Applications Of Synchrotron Techniques In Environmental Sciences, Hiram Castillo-Michel

Open Access Theses & Dissertations

In the last two decades, synchrotron based techniques have gained popularity and been increasingly used in environmental sciences. The present dissertation has relied significantly in the use of synchrotron based techniques to study the speciation, coordination, and distribution of toxic metal(loids) in plants. This study included three plant species: Parkinsonia florida, Prosopis juliflora, and Zea mays. P. florida is a plant species native to the semi-desert regions of North America. The cultivation characteristics of this shrub/tree suggest that it could be used for phytoremediation purposes in semiarid regions. P. florida plants were tested for their capacity to remove arsenic (As) …

Development Of A New Evolutionary Algorithm Based On Adaptive Echolocation Applied To A Multi Objective Version Of The Redundancy Allocation Problem, Karla Rocio Gutierrez

Open Access Theses & Dissertations

The intention of this research is to develop a new algorithm that it is mainly focus in the principle of echolocation or also called biosonar. This principle is active in many animals such as: birds, shrews, dolphins and bats, these last ones are going to be a fundamental part of our study. These animals use it as radar in order to find food, obstacles or just to locate objects.

These animals use ultrasound beams with a certain degree of angle and multiple receivers; such as the two ears that are located slightly apart, so at the time of the returning …

The Impact Of Sulfide Mineral Weathering On The Isotopic Signatures Of Fe And Cu In Metal-Rich Streams, Ana Lourdes Gutierrez

Open Access Theses & Dissertations

The oxidative weathering of sulfide minerals, like pyrite, at the Earth's surface controls the formation of acid mine drainage sites as well as the Fe isotope composition of these areas and the main processes taken place. In this study, water and rock samples were collected from acidic drainages (most from abandoned mining sites) from the St. Juan Mountains in Colorado. The water samples were measured in-situ for dissolved oxygen, dissolved Fe(II), pH, and conductivity. Filtered acidified, unfiltered acidified, and Fe-oxide samples were analyzed for their metal concentrations. Ion-exchange chromatography was applied to both water and digested oxide fractions in order …

Solving The Partial Differential Equation Of Vibrations With Interval Parameters Using The Interval Finite Difference Method, Brenda G. Medina

Open Access Theses & Dissertations

Accuracy and efficiency are among the main factors that drive today's innovative disciplines. As technology rapidly advances, efficiency takes on new meanings but what about accuracy? How accurate is accurate? Human error, uncertainties in measurement, and rounding errors are just some causes of inaccuracy. Interval Computations is an area that allows for such issues to be taken into account; for each measurement attained (for example), an interval can be built by considering the error associated with the measurement, and such an interval can be utilized in the mathematical computations of interest.

We consider the partial differential equation (PDE) of vibrations …

Biol 470.01: Ornithology, Richard L. Hutto

University of Montana Course Syllabi

No abstract provided.

Computational Methods Of Hidden Markov Models With Respect To Cpg Island Prediction In Dna Sequences, Roberto Angel Ortega

Open Access Theses & Dissertations

Hidden Markov models (HMM's) are a specific case of Markov models where, contrary to Markov chains, the observer is unaware of what state the model was in when the symbol is observed. Like Markov chains, HMM's assume that the future state of a sequence is dependent only on the current state of the sequence. The parameters associated with HMM's are transition and emission probabilities, where transition probabilities are associated with the probability of transitioning from one state to another, and emission probabilities are the probabilities associated with observing a symbol given it came from a specific state.

The structure of …

Wildlife Deterrent System: The "Scare Wave" Audio Deterrent System, Ferdd Mari C. Lansang, Kevin Wong

Electrical Engineering

The “Wildlife Deterrent System – The “SCARE WAVE” Audio Deterrent System” project involved working with a client, Mr. Robert Alberti, who requested the production of a device that would be used to scare away wildlife around his property, namely the Acorn Woodpecker. It was specified that this device be weatherproof and able to produce a 75 dB gunshot sound, when remotely triggered, which would cover a 30 ft radius circle of area. However, we have taken these specifications and went above and beyond with the final product. Our final product is weatherproofed and able to produce four user-specifiable, via provided …

Therapeutic Jurisprudence And Child Protection, Shelley Kierstead

Barry Law Review

No abstract provided.

Investigating Cell Line Identity And Gene Regulation In A Broad Array Of Human Hepatocellular Carcinoma, Ashley Mottar

Honors Capstones

Cultured cancer cell lines are a widely used approach in our biology research. Our lab uses several human liver cancer lines to study the role of two amino acid transporters (ASCT2 and LAT1) during growth. To validate the identity of each line for comparative results, a means of positive ID is needed. Short tandem repeat (STR) analysis is a method that uses the polymerase chain reaction (PCR) to examine 'w' specific DNA regions, called loci, which surround specific genes. Originally used in forensic analysis and paternity testing, STR analysis has recently become incorporated into research laboratories. The reason is due …

Testing The Advantage Of A Cancer-Associated Glutamine Transporter In Liver Cells, Arphy Roy

Honors Capstones

Neutral amino acid transporter ASCT2 is selectively over-expressed in cancerous liver cells. The purpose project was to test why this amino acid transporter was being expressed and to inquire the implicit advantage ASCT2 gives a cancer cell. This topic is of significance due to its relevance to cancer biology and of the prospect of designing cancer drug therapies that can exploit the ASCT2 transporter under inquiry. Growth study curves using varying concentrations of glutamine and cysteine with cell lines RLE human, rat, mouse and control empty vector were conducted to illustrate possible advantage in survival and growth. A Western blot …

The El Nino Southern Oscillation Climate System, Katherine Volk

Honors Capstones

The El Nino Southern Oscillation climate system, ENSO, is the largest coherent climate system on Earth. The variability of ENSO effects climate and environmental conditions across the globe, impacting the daily lives of hundreds of millions of people. There has been intensive study on the behavior of this system. While the mechanisms that control ENSO are now largely understood, the variability of these mechanisms is unknown. It is also unknown how ENSO will respond to global warming. Currently there is a void of data on the history of ENSO over the past several thousand years. A comprehensive record of ENSO …

The Role Of Lipoproteins/Cholesterol In Genomic Instability And Chromosome Mis-Segregation In Alzheimer's And Cardiovascular Disease, Antoneta Granic

USF Tampa Graduate Theses and Dissertations

Several lines of evidence link Alzheimer's disease (AD) to atherosclerosis (CVD), including that elevated low density lipoprotein (LDL)-cholesterol is a common risk factor. Development of genomic instability could also link the two diseases. Previous fluorescence in situ hybridization (FISH) analyses revealed a clonal expansion of aneuploid smooth muscle cells underlying atherosclerotic plaques. Likewise, cellular and mouse models of AD revealed tau-dependent mitotic defects and subsequent aneuploidy partly resulting from amyloid-beta (A&beta) interference with microtubule (MT) stability, and specific MT motors function. Moreover, AD patients develop aneuploid/hyperploid cells in brain and peripheral tissues, implicating similar mechanism that may lead to apoptosis …

Magneto-Dielectric Polymer Nanocomposite Engineered Substrate For Rf And Microwave Antennas, Cesar A. Morales

USF Tampa Graduate Theses and Dissertations

This dissertation presents the first reported systematic investigation on the implementation of multilayer patch antennas over Fe3O4-based polymer nanocomposite (PNC) magneto-dielectric substrates. The PNC substrate is created by the monodispersion of Fe3O4 nanopthesiss, with mean size of 7.5nm, in a polymeric matrix of Polydimethylsiloxane (PDMS).

Recently, magneto-dielectric substrates have been proposed by several researchers as a means for decreasing the size and increasing the bandwidth of planar antennas. Nevertheless, factors such as high loss and diminished control over magnetic and dielectric properties have hindered the optimal performance of antennas. In addition, the incompatibility and elevated complexity prevents integration of conventional …

Developmental Trajectories Of Self-Control: Assessing The Stability Hypothesis, James Vance Ray

USF Tampa Graduate Theses and Dissertations

A key proposition of Gottfredson and Hirschi's (1990) self-control theory is the stability hypothesis which suggests that an individual's level of self-control, once established between the ages of 8-10, is stable over the life course. Empirical results from examinations of the stability hypothesis have been mixed. Prior tests of the stability hypothesis have employed aggregate assessment methods (e.g., mean-level and correlational analyses). Such approaches fail to take into account the possibility that individual developmental pathways may differ. This study employs individual longitudinal data over a four year period for 3,249 7^th to 10^th grade subjects to assess the …

Evaluation Of Health Newsletters As A Motivational Tool To Promote Exercise, Jolene Schlegel

All Graduate Theses, Dissertations, and Other Capstone Projects

Little is known about the relationship between SagePlus newsletters and its effectiveness to motivate physical activity. The purpose of this study is to evaluate the impact of the SagePlus newsletter and its ability to motivate participants to achieve their goals to increase physical activity. A nonexperimental, descriptive correlational design was used in this study. Calls were made until the list of potential participants was exhausted. Forty English speaking participants were contacted and agreed to participate in the telephone survey from a potential list of 190 women enrolled in the SagePlus program. A modified questionnaire containing 19 multiple-choice and one open-ended …

Instructions For Authors, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Historical Perspectives On A Program For Mathematically Talented Students, Harvey B. Keynes, Jonathan Rogness

The Mathematics Enthusiast

The University of Minnesota Talented Youth Mathematics Program (UMTYMP) is a highly accelerated program for students who are extremely talented in mathematics. This paper describes our experiences running UMTYMP since its inception thirty years ago, the challenges in implementing such a program, and how changes in the student body have necessitated changes in the program over three decades.