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Brain-Derived Neurotrophic Factor Levels In D2 Receptor Primed Adolescent Rats Given Twice Daily Nicotine Administrations., Josie Minnigh

Undergraduate Honors Theses

Nicotine use is very prevalent in the schizophrenic population, which is a 2.5 fold greater than the general population. In the present study, the drug quinpirole (dopamine D2/D3 agonist) or saline was given neonatally to 25 Sprague-Dawley male and female rats. Rats were randomly assigned to condition. Beginning postnatal day 33 animals were given twice daily administrations of nicotine (0.5 mg/kg free base). After the first of the daily injections they were placed in a locomotor arena every other day for behavioral testing. One day after behavioral testing, the dorsal striatum and nucleus accumbens were removed for brain-derived neurotrophic factor …

Animal Companionship And Identity Construction In The Middle English "Ywain And Gawain", Robert E. Byers

English

As a relatively recent field within literary cultural studies, "animal studies" has the potential to ask sophisticated new questions about the central and privileged place of the humanist "cogito." Through an examination of the human-animal companionship found in the Middle English romance "Ywain and Gawain", this thesis aims to contribute to the project of animal studies by tracing how questions about humanity and animality both construct and deconstruct a subject's identity. In the poem, Ywain, a knight in Arthur's court, is exiled from society and befriends a lion, who travels and fights alongside him. The dynamics of their bond highlight …

Chancellor's Report 2011-12, John Pugh

Chancellor's Report

No abstract provided.

Using Local Knowledge, Hydrologic, And Climate Data To Develop A Driftwood Harvest Model In Interior Alaska, Chas Jones, Larry D. Hinzman, Knut Kielland

Research Posters

Rural Alaskan residents are concerned that the character of the summer discharge in the Yukon River is changing, which is affecting their ability to harvest driftwood. The Yukon River flows northwesterly through British Columbia and the Yukon Territory before flowing southwest through Alaska. In most summers, residents of Tanana, Alaska harvest driftwood from the Yukon River during two different periods. Typically, driftwood accompanies high flows on the Yukon River associated with spring break‐up. A few weeks later, a second series of driftwood appears, associated with the “2nd rise,” which is reported to occur during early June. This study examines the …

Hydrographic Controls And Seasonal Variability On The Carbonate System In The Northern Gulf Of Alaska, Kristen L. Shake

Marine Biology

The Northern Gulf of Alaska (GOA) supports a dynamic and economically viable marine ecosystem. One notable potential stressor to this ecosystem is ocean acidification (OA), a byproduct of the increased uptake of anthropogenic carbon dioxide (CO₂) by the ocean. Measurements of dissolved inorganic carbon (DIC) and total alkalinity (TA) were made along the continental shelf of the northern GOA and in Prince William Sound (PWS) and used to calculate seawater pH and the saturation state of aragonite Warp). Observations showed a high degree of seasonal variability in DIC concentrations in surface and bottom waters. TA was depleted relative to DIC …

The Role Of The Nascent Polypeptide-Associated Complex In Caenorhabditis Elegans, Paul T. Arsenovic

Masters Theses, 2010-2019

The nascent polypeptide-associated complex (NAC) is a highly conserved protein complex known to play an important role in the development of metazoan organisms, but its molecular function is not well understood. Recent evidence from experiments using Saccharomyces cerevisiae as model supported the hypothesis that the NAC is either a chaperone or a component of the cytosolic chaperone network that interacts with nascent peptides emerging from the ribosome. We tested this model in C. elegans and found that the homologues of the NAC , icd-1 and icd-2, behave like chaperones in the worm. Lack of icd-1 or icd-2 altered the worms …

A Case Study In Wetlands Conservation: Identifying Best Management Practices For Landowner Stewardship, Allison M. Bredbenner

Masters Theses, 2010-2019

This research explores wetlands conservation techniques employed by private landowners owning 1,000 or more acres who were recipients of an Environmental Law Institute National Wetlands Award. Study of private landowner stewardship is timely and important because in the United States, 75 percent of all wetlands are under private ownership. Given that wetlands provide a suite of valuable ecosystem services such as water filtration, flood abatement, and carbon storage, their conservation is critical to a healthy environment and productive economy. To accomplish this research, landowner files were processed into a digital archive and sub-categorized for research purposes. Telephone interviews were conducted …

The Examination Of The Feasibility Of Implementing A Biosphere Reserve In The Maltese Islands : Applying A Conservation Value Evaluation Framework, Alexander Borg

Masters Theses, 2010-2019

Biosphere reserves are protected areas which are internationally recognized within the United Nations Educational, Scientific and Cultural Organisation’s Man and the Biosphere Programme for promoting and establishing a balanced relationship between people and nature. Biosphere reserve management is guided by principles of biodiversity conservation; sustainable development; local, national and international partnership and support; local capacity-building; research and monitoring and co-operative management that is multidisciplinary, multi-stakeholder and locally-based. The research evaluated the feasibility of implementing the biosphere reserve concept in the Maltese Islands. This was studied by applying a conservation framework which consisted of holistic conservation value appraisal criteria – incorporating …

Investigating Hydrogen Enhanced Combustion In A Sustainability Context, Glenn Zammit

Masters Theses, 2010-2019

Since their invention, internal combustion engines have played a major role in the social and economic development of many countries by allowing people and goods to move from one place to another for longer distances and in shorter times. However, the negative environmental impacts of the widespread use of internal combustion engines in private and commercial vehicles have reached alarming values, with future prospects being much worse. In addition, fuel consumption and the dependency on oil imports of many countries have increased sharply in the past years as vehicle populations and use increased. The current trends are clearly unsustainable and …

Synthesis Of Resveratrol Esters And Aliphatic Acids., Stanley Mofor Jing

Electronic Theses and Dissertations

Resveratrol (RV) is a naturally occurring phytoalexin of the stilbenoid family produced by some plant species, and present in grape skin, peanuts, and red wine. It has been found to exhibit anti-cancer, anti-inflammatory, anti-viral, anti-aging, cardio protective, and anti-oxidant properties. Bioavailability is a huge setback that limits the potentials of RV. As a result, efforts have been made to design and synthesize RV esters and aliphatic acids in an attempt to increase its bioavailability, solubility in water, and possibly improving its biological activities. Resveratrol esters, 3,5,4'-triacetyloxystilbene (2) and Methyl 1,1',1''- (3,4',5-stilbenyl)-1,6-hexanedioate (3) have been synthesized. Compound 3 is a new …

Isolation Of A Rhodococcus Soil Bacterium That Produces A Strong Antibacterial Compound., Ralitsa Bogomilova Borisova

Electronic Theses and Dissertations

Rhodococci are notable for their ability to degrade a variety of natural and xenobiotic compounds. Recently, interest in Rhodococcus has increased due to the discovery of a large number of genes for secondary metabolism. Only a few secondary metabolites have been characterized from the rhodococci (including 3 recently described antibiotics). Twenty-four new Rhodococcus strains were isolated from soils in East Tennessee using acetonitrile enrichment culturing and identified using 16S rRNA analysis. Forty-seven Rhodococcus strains were screened for antibiotic production using a growth inhibition assay. One strain, MTM3W5.2, had 90% similarity to the Rhodococcus opacus 16S rRNA gene sequence and produced …

Determination Of Select Metal Ions In Commercially Available Conventional And Organic Baby Foods., Neva S. Winters

Electronic Theses and Dissertations

The goal of this study is to determine whether or not there is an appreciable difference between concentrations of various metal ions present in conventionally grown and processed and organically grown and processed baby foods. Two prominent, commercially available brands were chosen to undergo comparative studies between both their own conventional and organic varieties of second stage green beans and carrots. Samples were tested for cadmium, calcium, iron, lead, nickel, and zinc. Two containers of each variety of baby food were sampled in triplicate, with purchases of foods being made in separate areas to ensure that each set came from …

Genome-Wide Association Analysis Of Major Depressive Disorder And Its Related Phenotypes., Nagesh Ramarao Aragam

Electronic Theses and Dissertations

Major Depressive Disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. Thirteen to 14 million adults in the U.S. are believed to have MDD and an estimated 75% attempt suicide making MDD a major public health problem. Recently several genome-wide association (GWA) studies of MDD have been reported; however, few GWA studies focus on the analysis for MDD related phenotypes such as neuroticism and age at onset of MDD. The purpose of this study is to determine risk factors for MDD, identify genome-wide genetic variants affecting neuroticism and age at onset as quantitative …

Modified Organoclay Containing Chelating Ligand For Adsorption Of Heavy Metals In Solution., Mary Akuyea Addy

Electronic Theses and Dissertations

Presence of a chelating ligand in the clay structure significantly improves its ability to immobilize heavy metals from contaminated sludge or wastewater. Two-step modification procedure comprising sequential pillaring and grafting of chelating agent to the modified clay is involved.

Montmorillonite and kaolin were chosen as typical examples of expandable and non-expandable clays, correspondingly. Modifications with silica and ferric oxide were targeted on development of mesoporous structure. Laboratory tests of the organoclay efficiency for purification of wastewater were conducted with the most promising sample, i.e. organoclay with the highest specific loading of chelating agent. Experiments were conducted with model wastewater containing …

A Study Of The Effects Of Titanium Dioxide Nanoparticles On The Fluorescent Intensity Of Fluorescent Compounds In The Presence Of Known Quenchers., Vivian Dzigbodi Koka

Electronic Theses and Dissertations

Titanium Dioxide is a naturally occurring oxide of titanium. It has a wide range of uses in commercial products for providing whiteness and opacity. It has photocatalytic properties and can also be used to produce electricity in its nanoparticles form. This research is focused on investigating the effect of titanium dioxide nanoparticles in analysis of compounds using luminescence-based techniques. Quenching, which is one of the basic problems of fluorescent measurements, was studied in the presence of molecular oxygen and methyl iodide. The rutile phase of titanium dioxide nanoparticles was synthesized by the acid hydrolysis of titanium isobutoxide at low temperatures …

Does Ses Moderate The Relationship Between Temperament And Emotional And Behavioral Disorders?., Jessica L. Scott

Electronic Theses and Dissertations

This study explored whether the relationship between temperament and emotional and behavioral disorders (EBDs) is moderated by socioeconomic status (SES) in a sample of 73 children ages 5 through 15 years. Caregivers completed the Rothbart temperament surveys and the Child Behavior Checklist (CBCL). Indicators of SES included total household income and occupational status, while indicators of EBDs included the Internalizing Problems, Externalizing Problems, and Total Problems scales of the CBCL. Temperament variables included Fear, Frustration, Sadness, and Shyness. Hierarchical regression analyses revealed 4 regressions significant for moderation. A conclusion gleaned from these results is that the relationship between particular temperament …

Using Electrochemical Method To Study The Interaction Between Dna And A Compound Known To Have Anticancer Property., Alexander Kamasah

Electronic Theses and Dissertations

The interaction of 4-(1'-[8'-(1''-pyrenyl)naphthyl])-2,6-diaminopyridine bis-glycamide bishydrocholride known to have anticancer properties with deoxyribonucleic acid (DNA) had been studied on a modified gold electrode by self-assembled monolayer using cyclic voltammetry. K₄Fe (CN)₆ was used as a probe to obtain electrochemical information on the electrode surface.

A bare gold (Au) electrode was modified with cysteamine and our results showed no change in the limiting steady state current as compared to the bare Au electrode. There was a reduction in the steady state current after the modification of the gold electrode with DNA. Immobilization of the DNA modified gold electrode …

Synthesis Of Resveratrol Ester Derivatives Using Selective Enzymatic Hydrolysis., Marian Osei-Mensah

Electronic Theses and Dissertations

Resveratrol, a naturally derived stilbene, is an interesting compound mostly talked about recently because for its anti-cancer properties. Unfortunately it has some shortcomings due to its low bioavailability and low solubility in water. For this reason, my research is to overcome resveratrol's drawbacks by improving its bioavailability and hydrophilicity. My research is focused on syntheses of novel derivatives of resveratrol such as 3, 5-di-O-isobutyroyl resveratrol and 3, 5-di-O-hexanoyl resveratrol using lipase catalyzed hydrolysis. Therefore, the tri-acylated resveratrols 3, 5, 4'-tri-O-isobutyroyl resveratrol and 3, 5,4'-tri-O-hexanoyl resveratrol were first synthesized.

3,5,4'-tri-O-isobutyroyl resveratrol and 3,5,4'-tri-O-hexanoyl resveratrol were then hydrolyzed using lipase (C. …

Play Therapists’ Practice Patterns And Perceptions Of The Factors That Influence Caregiver Engagement In Play Therapy, Adrianne R. Lolan

LSU New Orleans Theses and Dissertations

Much effort has been expended to increase the awareness and understanding of play therapy among consumers and practitioners (Landreth, 1991) since its introduction by Virginia Axline during the 1940s. As with any form of counseling, Leblanc and Ritchie (1999) have noted there are factors considered key to successful play therapy treatment outcomes. Play therapy research shows a positive relationship between parent's involvement in play therapy and successful outcomes (LeBlanc & Ritchie, 1999; Bratton, Ray, Rhine, & Jones, 2005) but little research exists to document specific practice patterns and perceptions of play therapists in relation to achieving caregiver engagement. The purpose …

Ecosystem Management And Its Application At The Local Level: Apnep, Cama And Local Land Use Planning In North Carolina, Traci L. Birch

LSU New Orleans Theses and Dissertations

A fundamental purpose of state-mandated growth management has been to infuse regional environmental concerns into local land use planning. Similarly, collaborative ecosystem planning efforts have attempted to encourage local communities to participate in regional planning efforts, and to adopt regional environmental goals and objectives into local land use plans. This paper presents results from a study of state-mandated local planning and collaborative regional planning, addressing in particular local ability to adopt and implement ecosystem planning initiatives for development management.

I found that a state mandate not only achieves plans from communities that would not otherwise plan, but also the plans …

Multivariate Models And Algorithms For Systems Biology, Lipi Rani Acharya

LSU New Orleans Theses and Dissertations

Rapid advances in high-throughput data acquisition technologies, such as microarraysand next-generation sequencing, have enabled the scientists to interrogate the expression levels of tens of thousands of genes simultaneously. However, challenges remain in developingeffective computational methods for analyzing data generated from such platforms. In thisdissertation, we address some of these challenges. We divide our work into two parts. Inthe first part, we present a suite of multivariate approaches for a reliable discovery of geneclusters, often interpreted as pathway components, from molecular profiling data with replicated measurements. We translate our goal into learning an optimal correlation structure from replicated complete and incomplete …

Development Of A Novel Electron-Transfer Secondary Reaction Matrix, Characterization Of The Site–Specificity Of Novel Bilin-Lyase, And Fundulus Grandis Protein Expression Investigation Using Mass Spectrometry, Mohamed N. Boutaghou

LSU New Orleans Theses and Dissertations

Reported in this dissertation are the results of investigations performed at the New Orleans Center for Mass Spectrometry at the University of New Orleans. The projects that are detailed in the coming pages take on a variety of subjects, but a common thread is that each employs matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to solve a problem. Fundamental aspects of MALDI in-plume ionization are implicated in the introduction of a newly developed electron-transfer secondary ionization matrix. The remaining projects are related to the ever expanding field of proteomics. Mass spectrometry was used to investigate the site specificity of a newly …

Analysis Of Biomass/Coal Co-Gasification For Integrated Gasification Combined Cycle (Igcc) Systems With Carbon Capture, Henry A. Long Iii

LSU New Orleans Theses and Dissertations

In recent years, Integrated Gasification Combined Cycle Technology (IGCC) has become more common in clean coal power operations with carbon capture and sequestration (CCS). Great efforts have been spent on investigating ways to improve the efficiency, reduce costs, and further reduce greenhouse gas emissions. This study focuses on investigating two approaches to achieve these goals. First, replace the subcritical Rankine steam cycle with a supercritical steam cycle. Second, add different amounts of biomass as feedstock to reduce emissions. Finally, implement several types of CCS, including sweet- and sour-shift pre-combustion and post-combustion.

Using the software, Thermoflow®, this study shows that utilizing …

Habitat Characteristics Affecting Site Occupation In Wintering Henslow’S Sparrows At Mississippi Sandhill Crane National Wildlife Refuge, Mary E. Nicholson

LSU New Orleans Theses and Dissertations

Henslow’s sparrow (Ammodramus henslowii) winters in recently burned sites in pine savannas of the Southeastern United States. Previous studies have suggested that factors such as seed abundance and litter depth are important to wintering Henslow’s sparrows. My study asked how habitat variables including vegetation structure, seed abundance, and arthropod abundance predict Henslow’s sparrow site occupancy at Mississippi Sandhill Crane National Wildlife Refuge. In this study, Henslow’s sparrow more often occupied sites burned one growing season earlier than sites burned two growing seasons earlier, and did not occupy sites burned three or more growing seasons earlier. Data indicated that mass …

Self-Assemblies Driven By The Hydrophobic Effect, Haiying Gan

LSU New Orleans Theses and Dissertations

Water is a simple molecule but is an essential part of life. One key aspect of the properties of water is the hydrophobic effect, and whilst there is an appreciation of this phenomenon at the macro-scale (raindrops falling off leaves) and the micro-scale (the structure of cellular systems), a complete understanding at the molecular level still eludes science. Addressing this issue, our studies involve synthetic supramolecular compounds that assemble in water via the hydrophobic effect.

First of all, a novel water-soluble deep-cavity cavitand was synthesized. It possesses four endo methyl groups on top rim of the cavitand, eight water-solubilizing carboxylic …

Synthesis And Biological Evaluation Of Aeruginosin Based Compounds And Self-Assembly Of Glucosamine Based Compounds, Navneet Goyal

LSU New Orleans Theses and Dissertations

Aeruginosins are a family of marine natural products containing mostly non-proteogenic amino acids. These compounds contain a common 2-carboxy-6-hydroxy-octaindole (Choi) rigid bicyclic structure. Many aeruginosins are inhibitors for enzymes involved in the blood coagulation cascade, such as thrombin and Factor VIIa. In order to understand the structure activity relationship (SAR) of the aeruginosins and to discover novel anticoagulants with potentially improved inhibitory and pharmacokinetic properties, in the first part of my thesis I have discussed, synthesis of a series of novel analogs of aeruginosin 298-A, in which the Choi will be replaced with L-proline and oxygenated Choi analogs, and the …

Merely Misunderstood: Expressive, Receptive, And Pragmatic Language In Children With Disruptive Behavior Disorders, Monica L. Gremillion

LSU New Orleans Theses and Dissertations

Children with Disruptive Behavior Disorders (DBD), including Attention-Deficit/Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder (ODD) have poorer language skills compared to typically developing children; however, language as a potential risk factor for DBD has received little empirical attention or evaluation. Receptive, expressive, and pragmatic language skills in preschoolers with DBD were examined. Participants were 82 preschool-age children and their primary caregivers. Primary caregivers completed a semi-structured interview and symptom and language questionnaires. Preschoolers completed measures of receptive and expressive language. Results indicated that preschoolers with DBD were more impaired on receptive, expressive, and pragmatic language compared to non-DBD children. Pragmatic …

The Women And Peace Hypothesis In The Age Of Nancy Pelosi: Can Female Leaders Bring About World Peace?, Jeannette Haynie

LSU New Orleans Theses and Dissertations

The women and peace hypothesis suggests that women are more likely than men to choose peace and compromise over violent conflict, whether as ordinary citizens or as government leaders. I test this concept by analyzing the percent of women in the parliaments and executive cabinets of 93 nations over a 31-year-period, comparing these figures to the presence of violent interstate conflicts for each country-year. Controlling for wealth, democratic status, national capabilities, military expenditures, and contiguity, I find moderate support for the women and peace hypothesis. This support continues when democratic system type is interacted with the measured office. While women …

The Romani Place In Kosovar Space: Nationalism And Kosovo’S Roma, Melissa Hughes

LSU New Orleans Theses and Dissertations

On February 17, 2008,Kosovo declared its independence. The path to independence and the claim to Kosovo was a long process that developed in three primary phases: A) the fostering of territorial solidarity under direct rule and an emphasis on historical ties to the territory; B) the foundation of the national idea within the realms of proto-nationalism; and C) the emergence of peripheral and mass nationalism. This research seeks to define the development of nationalist ideologies in Kosovo and to explore where Roma fit within those ideologies. An historical and sociological approach to nationalism in Kosovo is critical in understanding the …

Evolutionary Relationships Among Duiker Antelope (Bovidae: Cephalophinae), Anne Johnston

LSU New Orleans Theses and Dissertations

Duikers are a species rich subfamily of threatened African antelope whose recent origin poses a challenge to the molecular identification of taxa and estimation of their phylogeny. I test the ability of DNA barcodes to identify all taxa within this group. I then use mitochondrial and nuclear genes to estimate a multi-locus species tree and to date divergence times. DNA barcodes are unable to distinguish many sister taxa, calling into question the utility of barcodes for the regulation of duiker trade or in identification of field-collected feces. The multi-locus phylogeny provides support for the relationships among major duiker lineages and …