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Molecular And Genomic Approaches To Understanding Host-Virus Interactions In Shaping The Outcome Of Equine Arteritis Virus Infection, Yun Young Go

University of Kentucky Doctoral Dissertations

Equine arteritis virus (EAV) is the causal agent of equine viral arteritis, a disease of equids. During natural outbreaks of the disease, EAV can cause abortion in pregnant mares and persistent infection in stallions. Understanding how host cellular proteins interact with viral RNA and viral proteins, as well as their role in viral infection, will enable better characterization of the pathogenesis of EAV and establishment of persistent infection in stallions. Accordingly, we hypothesized that both viral factors and host genetically related factors could influence the outcome of EAV infection in horses. To test this hypothesis, we first combined contemporary molecular …

Appalachian Bridges To The Baccalaureate: The Influence Of Multiple Roles And Cultural Norms On The Baccalaureate Persistence Of Location-Bound Appalachian Women, Nancy Coldiron Preston

University of Kentucky Doctoral Dissertations

Too few Kentucky community college students transfer and persist to earn baccalaureate degrees. This is particularly true in Appalachia Kentucky which has a high rate of poverty and a low rate of baccalaureate attainment. Scholars and economists agree that the fastest way to decrease poverty within a geographical region is to increase the educational level of the citizens. Policy makers in the Commonwealth have established a goal of doubling the number of baccalaureate holders within the state by 2020.

This study is framed by a collaborative study which examined the ways in which institutional and student characteristics impact the pathway …

Appalachian Bridges To The Baccalaureate: Institutional Perceptions Of Community College Transfer Success, Christopher M. Phillips

University of Kentucky Doctoral Dissertations

Statement of the problem. Appalachian community colleges are dealing with a dynamic transfer policy environment and implementing practices that either foster or impede transfer student success. The problem in this dissertation is to discern how Appalachian community colleges are making sense of transfer policy changes and conducting practices to address student transfer success. Although individual factors must be considered by community colleges, they often are out of the control of the institution. This study focused on the institutional factors, including the ways that organizational structures and transfer policies contribute to the success of a community college’s transfer program.

Design. This …

Three Essays Evaluating Choices Of Teachers And Administrators In Kentucky Public Schools, Nathan Barrett

University of Kentucky Doctoral Dissertations

Public K-12 education is a large enterprise in the United States. Through local, state and federal sources, the U.S. allocated over $610 billion to K-12 public education in 2009 (NCES). Not only is the commitment of public funds for education substantial, the provision of K-12 education is primarily administered by the government in non-market settings through local school districts. It is this institutional environment that generates the impetus for evaluating how those in education make choices in the absence of markets.

Like traditional markets, non-market solutions often fail because the incentives facing individuals and agencies elicit choices which produce outcomes …

Conceptualizing And Improving Red Wine Grape Cultivars Grown In Kentucky, Matthew Simson

University of Kentucky Master's Theses

Wine sensory attributes are associated with quality of wines. Cabernet Franc did not possess good coloration of its wine. Therefore, in the 2009 and 2010 growing seasons, studies including the sampling of four red wine grape cultivars from the end of flowering throughout the rest of the season and applying treatments to Cabernet Franc grapevines at veraison were commenced to address suitability and color enhancement, respectively. The study examining Cabernet Franc, Cabernet Sauvignon, Chambourcin, and Norton looked at sampling their grapes at two-week intervals from times post-flowering to understand the demands of each cultivar during key stages of berry development, …

Polyamine Modulation In Alcoholism: Examination Using A Novel Screening Procedure Designed To Predict Anti-Relapse And Neuroprotective Efficacy, J. Ben Lewis

University of Kentucky Doctoral Dissertations

Alcohol dependence is a major public health concern. Despite the FDA’s approval of multiple anti-relapse drugs, relapse rates remain unacceptably high. Furthermore, cognitive deficits among chronic drinkers are evident and are suggested to contribute to relapse risk. Current evidence suggests that several critical features of alcoholism and alcohol-associated neurodegeneration are mechanistically linked to glutamatergic actions; specifically, they appear positively affected by glutamatergic inhibition, particularly inhibition via polyamine modulation of a subpopulation of n-methyl-d-aspartate receptors. The current project was designed to evaluate the performance of two putative polyamine modulators (JR-220 and CP-101,606) in a variety of screens designed …

“Obtuse Women”: Venereal Disease Control Policies And Maintaining A “Fit” Nation, 1920-1945, Evelyn Ashley Sorrell

University of Kentucky Master's Theses

Public health officials and social reformers grew concerned over the prevalence of gonorrhea and syphilis following World War I. The initiatives put in place by authorities to control the spread of venereal disease lacked any concern for women’s health and sought to control their newly found independence and mobility. This thesis examines public health policies related to venereal disease control from 1920-1945 and how these regulations affected women in the United States. Laws and social reform measures such as pre-marital blood tests, the Sheppard-Towner Maternity and Infancy Act, and the use of quarantining prostitutes during World War I and World …

Social Capital, Solidarity, And Cohort Effect —An Analysis Of The Production Of Social Capital Among Union Miners In Harlan County, Kentucky, Feng Hao

University of Kentucky Master's Theses

The coal industry exercises a pervasive influence on mining communities in Appalachia, even though it exerts enormous damages on the environment and makes limited contributions to employment and the advancement of the communities. One explanation for this paradox offered by Bell is a depletion of social capital among coalfield residents in Central Appalachia (2009). Her data suggests that the “ripping away” of the region’s strong union identity lead to a resocialization, “from a ‘we’ mentality to an ‘I’ mentality, thus demising the store of social capital” (2009:655). My research aims to interpret how social capital resources among union miners was …

Examining Gender Differences In Persistence In Higher Education Among African American Students, Yvonne Townsend

University of Kentucky Master's Theses

This Study examined issues related to persistence in higher education among African American students, using the prominent model proposed by Vincent Tinto. The intentions were to examine the growing gender gap among African American students. The study examines factors from the Tinto model such as high school GPA, College GPA, college social integration and academic integration to try and explain the effects of gender among African American students. This research also attempts to elaborate the Tinto model by considering high school extracurricular activities as a pre-entry attribute that has an effect on persistence in higher education. Use of the Tinto …

Analyzing Educational Attainments And Occupational Outcomes Of Tibetan Refugees Living In India, Tenzin Palkyi

University of Kentucky Master's Theses

Opportunities of mass education are a relatively new phenomenon in the Tibetan community. Following the incidents of 1959, the Dalai Lama and thousands of Tibetans fled into India. Mass education was implemented and sustained within the Tibetan community for the first time. The goal of this exploratory research is to study the impact of mass education on the first generations of Tibetans who experienced it in exile. This study analyzes the gendered pattern in subjects students choose to pursue, their educational attainment and the kinds of jobs they assume after graduation. The study presents a quantitative analysis of data spanning …

The Effect Of Loose Mix Aging On The Performance Properties Of Warm Asphalts, Thomas Martin Clements

University of Kentucky Master's Theses

Recent improvements in warm mix asphalt technologies have spurred an aggressive adoption of these new practices within the asphalt paving industry. Concerns have arisen among federal and state agencies about the effects of this line of products on the performance of asphalt pavements. An investigation of the effects of lowering mixing, aging and compactions temperatures while varying the loose mix aging time was performed. Hamburg Wheel Tracking, Flow Number, Dynamic Modulus and Fracture Energy testing were used to evaluate mechanistic properties of the materials.

The Response Of Tall Fescue And Its Fungal Endophyte To Climate Change, Glade Blythe Brosi

University of Kentucky Master's Theses

Tall fescue is the most common cool-season grass in the eastern USA, with broad economic and ecological importance to the region. Tall fescue is known to associate with a fungal endophyte, Neotyphodium coenophialum, whose presence can decrease biotic and abiotic stress experienced by the plant. This thesis evaluates the response of tall fescue and the fungal endophyte symbiosis to predicted climate change. I participated in two multi-factor climate change projects where I investigated the response of tall fescue tissue chemistry and growth to various climate change factors. Endophyte-infected (E+) tall fescue had decreased alkaloid production under elevated CO_{2 …}

Optimization Of Coagulation And Syneresis Processes In Cheesemaking Using A Light Backscatter Sensor Technology, Tatiana Gravena Ferreira

University of Kentucky Master's Theses

Curd syneresis, a critical step in cheesemaking, directly influences the quality of cheese. The syneresis process is empirically controlled in cheese manufacturing plants. A sensor technology for this step would improve process control and enhance cheese quality. A light backscatter sensor with a Large Field of View (LFV) was tested using a central composite design over a broad range of cheese process conditions including milk pH, calcium chloride addition level, milk fat to protein ratio, temperature, and a cutting time factor (β). The research objectives were to determine if the LFV sensor could monitor coagulation and syneresis steps …

A Classification Of Lower Paleozoic Carbonate-Bearing Rocks For Geotechnical Applications, Bethany L. Overfield

University of Kentucky Master's Theses

An empirically-based classification of lower Paleozoic carbonate-bearing rocks was created for field-based geotechnical applications. Geotechnical parameters were subsequently correlated to that classification. Seven hundred seventy-seven samples were used as the basis for the classification. Thirteen categories based on visual and tactile properties and a hydrochloric acid test were created. Samples were from central, north-central, and south-central Kentucky and represented the majority of Ordovician exposures in the state, and some Mississippian exposures. Few Silurian and Devonian units were included in the sample set. Geotechnical parameters, including density as well as elastic constants (shear and compression wave velocities, Poisson’s ratio, Young’s modulus, …

Analysis Of Student & Teacher Outcomes From Pre-Existing Data Obtained Through The Low Incidence Initiative: Teaching Academic Age-Appropriate Learning Via Communication Project, April M. Holman

University of Kentucky Master's Theses

Students with significant cognitive disabilities frequently exhibit reduced communicative and academic competence. The Low Incidence Initiative (LII) project was a professional development model designed to train school-based teams to facilitate increased communicative and academic competence with such students via distance-technology coaching. This study analyzed pre-existing data from year one of the LII. Data were analyzed to determine effectiveness of the project on communication status of students and on training school personnel to accurately identify student levels of communication, and for overall satisfaction with the project. Results indicated that all student participants demonstrated improvement in expressive communication output. 100% of students …

Effects Of Midstory Removal On Black Oak (Quercus Velutina) And White Oak (Quercus Alba) Regeneration, David Lee Parrott

University of Kentucky Master's Theses

The formation of dense understories in eastern forests has created low light environments that hinder the development of advance oak reproduction. Studies have shown that a midstory removal can enhance these light conditions and promote the development of competitive oak seedlings. Previous studies have been primarily focused on oaks found on productive sites, and there is little knowledge of this treatment’s potential on intermediate sites and the typically associated oak species. This study investigates the seven-year effects of midstory removal on natural and underplanted white (Quercus alba L.) and black oak (Quercus velutina L.) reproduction, as …

Investigation Of The Toxicity And Efflux Of Polychlorinated Biphenyls And Hydroxylated Polychlorinated Biphenyls In Escherichia Coli, Shen Geng

University of Kentucky Master's Theses

Polychlorinated biphenyls (PCBs) are persistent organic pollutants. Due to their properties, PCBs accumulate in the food-chain and post a threat to the health of human beings and wildlife. Hydroxylated PCBs (OH-PCBs) are oxidative metabolites of PCBs and are more hydrophilic than their parent PCBs. One of the best approaches to break down these contaminants is through bioremediation, which is an environmental friendly process that uses microorganisms to restore natural environment.

Towards this goal, we have investigated the toxicity and accumulation of PCBs and OH-PCBs in a Gram-negative bacterium, Escherichia coli. We have also determined the role played by a …

Use Of Copper Sulfate To Control Haemonchus Contortus Infestation In Hampshire Ewes, Melinda Mallory Simpson

University of Kentucky Master's Theses

Two studies were conducted to evaluate the effectiveness of using copper sulfate (CuSO₄) as a drench in Hampshire ewes to control stomach worms (Haemonchus contortus).

A study was conducted to assess the effectiveness of CuSO₄ to control gastrointestinal nematodes (GIN) over a three year period. Ewes were FAMACHA scored, hematocrit evaluated for packed cell volume (PCV), and fecal egg counts (FEC) were determined from 2007 through 2009. Ewes received only CuSO₄ to control GIN. Ewes with FEC exceeding 6,000 eggs/g feces were drenched.

A separate study during the summer of 2008 assessed the potential …

Constrained Volume Packing Of Deployable Wings For Unmanned Aircraft, Turner John Harris

University of Kentucky Master's Theses

UAVs are becoming an accepted tool for sensing. The benefits of deployable wings allow smaller transportation enclosures such as soldier back packs up to large rocket launched extraterrestrial UAVs. The packing of soft inflatable wings and Hybrid inflatable with rigid section wings is being studied at the University of Kentucky. Rigid wings are volume limited while inflatable wings are mass limited. The expected optimal wing design is a hybrid approach. Previous wing designs have been packed into different configurations in an attempt to determine the optimal stowed configurations. A comparison of rigid, hybrid, and inflatable wings will be presented. Also …

Small Mammal Populations In Switchgrass Stands Managed For Biomass Production Compared To Hay And Corn Fields In Kentucky, Laura Mary Jane Schwer

University of Kentucky Master's Theses

Switchgrass (Panicum virgatum), a native warm-season grass, has been investigated as a renewable energy crop that may provide viable wildlife habitat. This study investigated small mammal populations in switchgrass, hay, and corn to assess the relative habitat quality. Four, three-night trapping sessions were conducted at four locations in Kentucky using Sherman livetraps. Trapping occurred in spring (before first hay harvest), summer, fall (before switchgrass and corn harvest), and winter (post-harvest). Relative abundance of small mammals, calculated using a capture per unit effort index (per 100 trapnights), and mean taxonomic richness were used to compare habitats. Switchgrass had a …

“You’Re Surviving But I Don’T See How You’Re Living” Appalachian Women Talk About Tanf And Employment In Their Communities, Pon-Chu Tsou

University of Kentucky Master's Theses

This thesis studies qualitative data to examine the lived experiences of Kentucky Transitional Assistance Program (K-TAP) recipients in Appalachian Kentucky. This research suggests that PRWORA legislation utilize the importance of place-based analyses to implement and evaluate poverty policy. For women who are attempting to meet PRWORA’s goals, the local services available to the women and the barriers they face to employment highlight the role place has in this national policy discussion. Of the women interviewed, recipients who resided in economically distressed areas had fewer opportunities to participate in employment activities than women in at-risk or transitional areas. While many strived …

Nongovernmental Organizations And Sex Work In Cambodia: Development Perspectives And Feminist Agendas, Jessica Catherine Schmid

University of Kentucky Master's Theses

This project focuses on nongovernmental organizations (NGOs) in Cambodia that deal, either directly or indirectly, with sex work and sex workers. The NGOs outlined in this study have goals ranging from preventing Cambodian women from entering the commercial sex industry to empowering Cambodian sex workers through the formation of sex worker unions. Through the textual analysis of documents and web materials disseminated by these NGOs and from interviews with representatives from the NGOs, I seek to analyze how underlying assumptions about development and about the commercial sex industry shape the ways in which the personnel leading these NGOs think and …

An Investigation Of The Reynolds Number Dependence Of The Near-Wall Peak In Canonical Wall Bounded Turbulent Channel Flow, Bahareh Estejab

University of Kentucky Master's Theses

An experimental investigation into fully developed high aspect ratio channels was undertaken. A review of the literature reveals that there is a need for accurate measurement of the inner peak value of streamwise turbulence intensity despite the large number of studies already completed. The scattered data on this subject could be attributed either to insufficient channel size (aspect ratio or length) or to hot-wire spatial filtering.

A new, high quality, channel flow facility was designed and constructed, considering the most recent geometric limitation provided in the literature. To obtain accurate results, data were acquired using hot-wire probes with constant viscous-scale …

Fate Of Stable Isotope Label During Predation Of 15N-Tagged Wild-Type Escherichia Coli By Protozoa, Ashley M. Barton

University of Kentucky Master's Theses

Currently, bacterial movement in karst aquifers is not well understood. Use of stable isotopes to label non-pathogenic Escherichia coli as a particulate groundwater tracer in karst systems has been examined in previous studies. Loss of the stable isotope signal is anticipated in traces greater than 500 m in length. Potential loss of ¹⁵N due to predation by protozoa was examined. Filter-sterilized water from Royal Spring in Georgetown, Kentucky, was inoculated with a mixture of either Tetrahymena pyriformis or Colpoda steinii and ¹⁵N-enriched E. coli and stored in the dark at 14°C. Samples were analyzed for their nitrogen isotope …

Cultivating Miracle Perceptions: Cultivation Theory And Medical Dramas, Rachael A. Record

University of Kentucky Master's Theses

This thesis reports the results of a study designed to investigate the influence of exposure to televised medical dramas on perceptions of medical miracles. Four hundred and eighty-one college students participated in a survey in which they responded to different questions about their medical drama viewership and their different beliefs with regard to medical miracles. Results found that heavy medical drama viewers perceived belief in medical miracles to be less normal than non-viewers. Similarly, heavy viewers perceived medical miracles to occur less often than non-viewers. Interestingly, heavy viewers perceived medical dramas to be less credible than non-viewers. In addition, this …

Perceptions Of Support, Likelihood Of Retention, And Differences Between Places Of Origin Among First-Generation College Students, Teresa Radomski

University of Kentucky Master's Theses

First-generation college students are less likely to attend and complete college than their peers whose parents have completed college. Among the reasons cited for this disparity is lack of parental familiarity of the college admissions process and financial aid opportunities. First-generation youth wishing to pursue a college education must rely on others for this knowledge. This study examines first-generation college students' perceptions of support and whether their places of origin have any bearing on their future plans. The study examines interviews with participants through the lens of Tinto's (1993) model of student departure to examine whether their responses, and whether …

Determining Interstellar Reddening: A New Approach Using Spectroscopy And Photometry, Syed A. Uddin

University of Kentucky Master's Theses

The mystery of Canis Major overdensity is addressed. We discuss concurrent methods and their limitations on the determination of interstellar reddening. We establish a new way to determine line of sight interstellear reddening by observing stellar spectral lines and UBV colors. We observe and analyze spectra of 22 stars in different open clusters. We find that Hydrogen Balmer line at 4861 angstrom can predict the stellar atmospheric parameters and intrinsic colors with reasonable accuracy. Comparing with observed colors we derive the reddening of the stars. We compare our results with standard database WEBDA and find that within 90% probability limit …

The Effect Of Practice On Eye Movements In The 1/D Paradigm, Will Seidelman

University of Kentucky Master's Theses

Previous studies have demonstrated that observers may ignore highly salient feature singletons during a conjunction search task through focusing the attentional window (Belopolsky, Zwaan, Theeuwes, & Kramer, 2007), or by the suppression of bottom-up information (Treisman & Sato, 1990). In the current study, observers’ eye movements were monitored while performing a search task in which a feature singleton was present and corresponded with the target at a chance level. With practice, observers were less likely to make an initial saccade toward the singleton item, but initial saccades directed at the target were likely throughout. Results demonstrate that, in an effort …

“What’S Happening” @Twitter: A Uses And Gratifications Approach, Corey Leigh Ballard

University of Kentucky Master's Theses

The uses and gratifications approach places power in the hands of the audience and is a helpful perspective when trying to understand media usage, exposure, and effects. However, while the uses and gratifications approach has been applied regularly to traditional media, research explaining why people use new social media networks as well as the gratifications they obtain from them is scarce at best. This thesis provides a comprehensive overview of the uses and gratifications approach as well as the current literature about social media networks. An argument is built within the thesis to study Twitter as one social media network …

Teacher Disclosure: Developing Privacy Rules, Managing Boundaries And Building Relationships, Renee Monique Kaufmann

University of Kentucky Master's Theses

The roles and responsibilities of middle school teachers are never ending. From instructing students on state-mandated curriculum to the enrichment of character and inquiry, teachers make daily decisions about how and what to disclose to their students. The current study reexamines Hosek and Thompson’s (2009) study on how teachers develop privacy rules and coordinate boundaries using Petronio’s Communication Privacy Management as the theoretical framework. Studying middle school teachers, in lieu of college instructors, allows for a better understanding of how privacy rules and boundaries are constructed and used within the middle school. This provides a better understanding of the important …